Same-sex mating and the origin of the Vancouver Island Cryptococcus gattii outbreak

Nature

Volumn 437, Issue 7063, 2005, Pages 1360-1364

  Fraser, James A ^a   Giles, Steven S ^a   Wenink, Emily C ^a   Geunes Boyer, Scarlett G ^a   Wright, Jo Rae ^a   Diezmann, Stephanie ^a   Allen, Andria ^a   Stajich, Jason E ^a   Dietrich, Fred S ^a   Perfect, John R ^a   Heitman, Joseph ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; BIODIVERSITY; CELLS; GENES;

GENEALOGY; HUMAN PATHOGENS; MYOBACTERIUM LEPRAE; SAME-SEX MATING;

GENETIC ENGINEERING;

PATHOGEN;

ANIMAL EXPERIMENT; ARTICLE; CANADA; CRYPTOCOCCOSIS; CRYPTOCOCCUS; CRYPTOCOCCUS GATTII; FEMALE; FUNGAL VIRULENCE; FUNGUS SPORE; GENOTYPE; GEOGRAPHY; INBREEDING; MATING; MOUSE; NONHUMAN; PARENT; PATHOGENESIS; POPULATION; PRIORITY JOURNAL; PROGENY; REPRODUCTION; SAME SEX MATING;

ANIMALIA; FUNGI; MYCOBACTERIUM LEPRAE; TOXOPLASMA GONDII;

EID: 27644483074     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature04220     Document Type: Article

References (30)

1. Monot, M. et al. On the origin of leprosy. Science 308, 1040-1042 (2005).
2. Su, C. et al. Recent expansion of Toxoplasma through enhanced oral transmission. Science 299, 414-416 (2003).
3. Hoang, L. M., Maguire, J. A., Doyle, P., Fyfe, M. & Roscoe, D. L. Cryptococcus neoformans infections at Vancouver Hospital and Health Sciences Centre (1997-2002): epidemiology, microbiology and histopathology. J. Med. Microbiol. 53, 935-940 (2004).
4. Casadevall, A. & Perfect, J. R. Cryptococcus neoformans (ASM Press, Washington DC, 1998).
5. Kwon-Chung, K. J., Boekhout, T., Fell, J. W. & Diaz, M. Proposal to conserve the name Cryptococcus gattii against C. hondurianus and C. bacillisporus (Basidiomycota, Hymenomycetes, Tremellomycetiadae). Toxon 51, 804-806 (2002).
6. Ruiz, A. & Bulmer, G. S. Particle size of airborn Cryptococcus neoformans in a tower. Appl. Environ. Microbiol. 41, 1225-1229 (1981).
7. Sukroongreung, S., Kitiniyom, K., Nilakul, C. & Tantimavanich, S. Pathogenicity of basidiospores of Filobasidiella neoformans var. neoformans. Med. Mycol. 36, 419-424 (1998).
8. Hull, C. M. & Heitman, J. Genetics of Cryptococcus neoformans. Annu. Rev. Genet. 36, 557-615 (2002).
9. Fraser, J. A., Subaran, R. L., Nichols, C. B. & Heitman, J. Recapitulation of the sexual cycle of the primary fungal pathogen Cryptococcus neoformans var. gattii: implications for an outbreak on Vancouver Island, Canada. Eukaryot. Cell 2, 1036-1045 (2003).
10. Kidd, S. E. et al. A rare genotype of Cryptococcus gattii caused the cryptococcosis outbreak on Vancouver Island (British Columbia, Canada). Proc. Natl Acad. Sci. USA 101, 17258-17263 (2004).
11. Lin, X., Hull, C. M. & Heitman, J. Sexual reproduction between partners of the same mating type in Cryptococcus neoformans. Nature 434, 1017-1021 (2005).
12. Boekhout, T. et al. Hybrid genotypes in the pathogenic yeast Cryptococcus neoformans. Microbiol. 147, 891-907 (2001).
13. Litvintseva, A. P., Thakur, R., Vilgalys, R. & Mitchell, T. G. Multilocus sequence typing reveals three genetically distinct subpopulations of Cryptococcus neoformans var. grubii (serotype A), including a unique population in Botswana. Genetics (in the press).
14. Maiden, M. C. et al. Multilocus sequence typing: a portable approach to the identification of clones within populations of pathogenic microorganisms. Proc. Natl Acad. Sci. USA 95, 3140-3145 (1998).
15. Hull, C. M., Boily, M. J. & Heitman, J. Sex-specific homeodomain proteins Sxi1α and Sxi2a coordinately regulate sexual development in Cryptococcus neoformans. Eukaryot. Cell 4, 526-535 (2005).
16. Fraser, J. A. et al. Convergent evolution of chromosomal sex-determining regions in the animal and fungal kingdoms. PLoS Biol. 2, 2243-2255 (2004).
17. Diaz, M. R., Boekhout, T., Theelen, B. & Fell, J. W. Molecular sequence analyses of the intergenic spacer (IGS) associated with rDNA of the two varieties of the pathogenic yeast, Cryptococcus neoformans. Syst. Appl. Microbiol. 23, 535-545 (2000).
18. Campbell, L. T. et al. Clonality and recombination in genetically differentiated subgroups of Cryptococcus gattii. Eukaryot. Cell 4, 1403-1409 (2005).
19. Campbell, L. T. et al. Clinical and environmental isolates of Cryptococcus gattii from Australia that retain sexual fecundity. Eukaryot. Cell 4, 1410-1419 (2005).
20. Halliday, C. L. & Carter, D. A. Clonal reproduction and limited dispersal in an environmental population of Cryptococcus neoformans var. gattii isolates from Australia. J. Clin. Microbiol. 41, 703-711 (2003).
21. Loftus, B. J. et al. The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans. Science 307, 1321-1324 (2005).
22. Kwon-Chung, K. J. A new species of Filobasidiella, the sexual state of Cryptococcus neoformans B and C serotypes. Mycologia 68, 943-946 (1976).
23. Shimizu, K. K. et al. Darwinian selection on a selfing locus. Science 306, 2081-2084 (2004).
24. Wickes, B. L., Mayorga, M. E., Edman, U. & Edman, J. C. Dimorphism and haploid fruiting in Cryptococcus neoformans: association with the α-mating type. Proc. Natl Acad. Sci. USA 93, 7327-7331 (1996).
25. Grigg, M. E., Bonnefoy, S., Hehl, A. B., Suzuki, Y. & Boothroyd, J. C. Success and virulence in Toxoplasma as the result of sexual recombination between two distinct ancestries. Science 294, 161-165 (2001).
26. Thomas, C. F. Jr & Limper, A. H. Pneumocystis pneumonia. N. Engl. J. Med. 350, 2487-2498 (2004).
27. Gaunt, M. W. et al. Mechanism of genetic exchange in American trypanosomes. Nature 421, 936-939 (2003).
28. Alano, P. & Carter, R. Sexual differentiation in malaria parasites. Annu. Rev. Microbiol. 44, 429-449 (1990).
29. Thompson, J. D., Higgins, D. G. & Gibson, T. J. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22, 4673-4680 (1994).
30. Cox, G. M. et al. Superoxide dismutase influences the virulence of Cryptococcus neoformans by affecting growth within macrophages. Infect. Immun. 71, 173-180 (2003).