Capsules from pathogenic and non-pathogenic Cryptococcus spp. manifest significant differences in structure and ability to protect against phagocytic cells

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  de Araujo, Glauber S ^a,b   Fonseca, Fernanda L ^b   Pontes, Bruno ^b   Torres, Andre ^c   Cordero, Radames J B ^d   Zancopé Oliveira, Rosely M ^c   Casadevall, Arturo ^d   Viana, Nathan B ^b   Nimrichter, Leonardo ^b   Rodrigues, Marcio L ^b   Garcia, Eloi S ^a,e   de Souza, Wanderley ^a,b   Frases, Susana ^a,b  

^a INSTITUTO NACIONAL DE METROLOGIA   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c Funda??o Oswaldo Cruz   (Brazil)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^e INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

GALACTOSE; GLUCOSE; GLUCURONIC ACID; INDIAN INK; MANNOSE; N ACETYLGLUCOSAMINE; POLYSACCHARIDE; XYLOSE; FUNGAL PROTEIN; FUNGUS ANTIGEN; MONOCLONAL ANTIBODY; MONOSACCHARIDE;

AMOEBA (LIFE CYCLE STAGE); ANTIBODY LABELING; ANTIGEN SPECIFICITY; ARTICLE; CELL SURFACE; CONTROLLED STUDY; CRYPTOCOCCUS; CRYPTOCOCCUS LIQUEFACIENS; CRYPTOCOCCUS NEOFORMANS; FUNGAL STRUCTURES; FUNGAL VIRULENCE; FUNGUS GROWTH; FUNGUS IMMUNITY; FUNGUS ISOLATION; FUNGUS MUTANT; MACROMOLECULE; MICROMORPHOLOGY; MOLECULAR WEIGHT; NONHUMAN; PHAGOCYTE; SPECIES DIFFERENCE; STRUCTURE ANALYSIS; VISCOSITY; YEAST; YEAST CELL; YOUNG MODULUS; ZETA POTENTIAL; ACANTHAMOEBA CASTELLANII; ANIMAL; BACTERIAL MEMBRANE; CHEMISTRY; CYTOLOGY; ELASTICITY; GENETICS; GROWTH, DEVELOPMENT AND AGING; HYDRODYNAMICS; IMMUNOLOGY; ISOLATION AND PURIFICATION; KINETICS; LIGHT; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHAGOCYTOSIS; RADIATION SCATTERING; SEQUENCE ALIGNMENT; SNAIL;

AMOEBA (GENUS); BACTERIA (MICROORGANISMS); CRYPTOCOCCUS GATTII; CRYPTOCOCCUS LIQUEFACIENS; EUKARYOTA; FILOBASIDIELLA NEOFORMANS; MAMMALIA;

ACANTHAMOEBA CASTELLANII; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, FUNGAL; BACTERIAL CAPSULES; BASE SEQUENCE; CRYPTOCOCCUS; ELASTICITY; FUNGAL PROTEINS; HYDRODYNAMICS; KINETICS; LIGHT; MOLECULAR SEQUENCE DATA; MONOSACCHARIDES; PHAGOCYTES; PHAGOCYTOSIS; SCATTERING, RADIATION; SEQUENCE ALIGNMENT; SNAILS; VISCOSITY;

EID: 84855805898     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0029561     Document Type: Article

References (51)

1. Khawcharoenporn T, Apisarnthanarak A, Mundy LM, (2007) Non-neoformans cryptococcal infections: a systematic review. Infection 35: 51-8.
2. Petter R, Kang BS, Boekhout T, Davis BJ, Kwon-Chung KJ, (2001) A survey of heterobasidiomycetous yeasts for the presence of the genes homologous to virulence factors of Filobasidiella neoformans, CNLAC1 and CAP59. Microbiology 147: 2029-36.
3. Casadevall A, Perfect JR, (1998) Cryptococcus neoformans, vol. ASM Press.
4. Burnik C, Altintas ND, Ozkaya G, Serter T, Selcuk ZT, et al. (2007) Acute respiratory distress syndrome due to Cryptococcus albidus pneumonia: case report and review of the literature. Med Mycol 45: 469-73.
5. De Castro LE, Sarraf OA, Lally JM, Sandoval HP, Solomon KP, et al. (2005) Cryptococcus albidus keratitis after corneal transplantation. Cornea 24: 882-3.
6. Garelick JM, Khodabakhsh AJ, Lopez Y, Bamji M, Lister M, (2004) Scleral ulceration caused by Cryptococcus albidus in a patient with acquired immune deficiency syndrome. Cornea 23: 730-1.
7. Johnson LB, Bradley SF, Kauffman CA, (1998) Fungaemia due to Cryptococcus laurentii and a review of non-neoformans cryptococcaemia. Mycoses 41 (7-8): 277-80.
8. Garcia-Solache MA, Casadevall A, (2011) Global warming will bring new fungal diseases for mammals. MBio 1.
9. Bergman A, Casadevall A, (2011) Mammalian endothermy optimally restricts fungi and metabolic costs. MBio 1.
10. Dong ZM, Murphy JW, (1995) Effects of the two varieties of Cryptococcus neoformans cells and culture filtrate antigens on neutrophil locomotion. Infect Immun 63: 2632-44.
11. Kozel TR, Gulley WF, Cazin J, (1977) Immune response to Cryptococcus neoformans soluble polysaccharide: immunological unresponsiveness. Infect Immun 18: 701-7.
12. Murphy JW, Cozad GC, (1972) Immunological unresponsiveness induced by cryptococcal capsular polysaccharide assayed by the hemolytic plaque technique. Infect Immun 5: 896-901.
13. Pirofski LA, (2001) Polysaccharides, mimotopes and vaccines for fungal and encapsulated pathogens. Trends Microbiol 9: 445-51.
14. Vecchiarelli A, Retini C, Pietrella D, Monari C, Tascini C, et al. (1995) Downregulation by cryptococcal polysaccharide of tumor necrosis factor alpha and interleukin-1 beta secretion from human monocytes. Infect Immun 63: 2919-23.
15. Doering TL, (2000) How does Cryptococcus get its coat? Trends Microbiol 8: 547-53.
16. McFadden D, Zaragoza O, Casadevall A, (2006) The capsular dynamics of Cryptococcus neoformans. Trends Microbiol 14: 497-505.
17. Rodrigues ML, Fonseca FL, Frases S, Casadevall A, Nimrichter L, (2009) The still obscure attributes of cryptococcal glucuronoxylomannan. Med Mycol pp. 1-7.
18. Zaragoza O, Rodrigues ML, De Jesus M, Frases S, Dadachova E, et al. (2009) The capsule of the fungal pathogen Cryptococcus neoformans. Adv Appl Microbiol 68: 133-216.
19. Bacon BER, Cherniak K, Kwon-Chung J, Jacobson ES, (1996) Structure of the O-deacetylated glucuronoxylomannan from Cryptococcus neoformans Cap70 as determined by 2D NMR spectroscopy. Carbohydr Res 283: 95-110.
20. Cherniak R, Sundstrom JB, (1994) Polysaccharide antigens of the capsule of Cryptococcus neoformans. Infect Immun 62: 1507-12.
21. Cherniak R, Valafar H, Morris LC, Valafar F, (1998) Cryptococcus neoformans chemotyping by quantitative analysis of 1 H nuclear magnetic resonance spectra of glucuronoxylomannans with a computer-simulated artificial neural network. Clin Diagn Lab Immunol 5: 146-59.
22. McFadden DC, Fries BC, Wang F, Casadevall S, (2007) Capsule structural heterogeneity and antigenic variation in Cryptococcus neoformans. Eukaryot Cell 6: 1464-73.
23. Cordero RJ, Frases S, Guimaraes AJ, Rivera J, Casadevall A, (2011) Evidence for branching in cryptococcal capsular polysaccharides and consequences on its biological activity. Mol Microbiol 79: 1101-17.
24. Fonseca FL, Nohara LL, Cordero RJB, Frases S, Casadevall A, et al. (2011) Immunomodulatory effects of serotype B glucuronoxylomannan from Cryptococcus gattii correlate with polysaccharide diameter. Infect Immun 78: 3861-70.
25. Frases S, Nimrichter L, Viana NB, Nakouzi A, Casadevall A, (2008) Cryptococcus neoformans capsular polysaccharide and exopolysaccharide fractions manifest physical, chemical, and antigenic differences. Eukaryot Cell 7: 319-27.
26. Frases S, Pontes B, Nimrichter L, Rodrigues ML, Viana NB, et al. (2009) The elastic properties of the Cryptococcus neoformans capsule. Biophys J 97: 937-45.
27. Frases S, Pontes B, Nimrichter L, Viana NB, Rodrigues ML, et al. (2009) Capsule of Cryptococcus neoformans grows by enlargement of polysaccharide molecules. Proc Natl Acad Sci U S A 106: 1228-33.
28. Small JM, Mitchell TG, (1986) Binding of purified and radio iodinated capsular polysaccharides from Cryptococcus neoformans serotype A strains to capsule-free mutants. Infect Immun 54: 742-50.
29. Zerpa R, Huicho L, Guillen A, (1996) Modified India ink preparation for Cryptococcus neoformans in cerebrospinal fluid specimens. J Clin Microbiol 34: 2290-1.
30. Nimrichter L, Frases S, Cinelli LP, Viana NB, Nakouzi A, et al. (2007) Self-aggregation of Cryptococcus neoformans capsular glucuronoxylomannan is dependent on divalent cations. Eukaryot Cell 6: 1400-10.
31. Fonseca FL, Nimrichter L, Cordero RJ, Frases S, Rodrigues J, et al. (2009) Role for chitin and chitooligomers in the capsular architecture of Cryptococcus neoformans. Eukaryot Cell 8: 1543-53.
32. Rodrigues ML, Alvarez M, Fonseca FL, Casadevall A, (2008) Binding of the wheat germ lectin to Cryptococcus neoformans suggests an association of chitinlike structures with yeast budding and capsular glucuronoxylomannan. Eukaryot Cell 7: 602-9.
33. Fonseca FL, Frases S, Casadevall A, Fischman-Gompertz O, Nimrichter L, et al. (2009) Structural and functional properties of the Trichosporon asahii glucuronoxylomannan. Fungal Genet Biol 46: 496-505.
34. Melcher GP, Reed KD, Rinaldi MG, Lee JW, Pizzo PA, et al. (1991) Demonstration of a cell wall antigen cross-reacting with cryptococcal polysaccharide in experimental disseminated trichosporonosis. J Clin Microbiol 29: 192-6.
35. Casadevall A, Mukherjee J, Scharff MD, (1992) Monoclonal antibody based ELISAs for cryptococcal polysaccharide. J Immunol Methods 154: 27-35.
36. Nakouzi A, Valadon P, Nosanchuk J, Green N, Casadevall A, (2001) Molecular basis for immunoglobulin M specificity to epitopes in Cryptococcus neoformans polysaccharide that elicit protective and nonprotective antibodies. Infect Immun 69: 3398-409.
37. Bolanos B, Mitchell TG, (1989) Phagocytosis of Cryptococcus neoformans by rat alveolar macrophages. J Med Vet Mycol 27: 203-17.
38. Chrisman CJ, Alvarez M, Casadevall A, (2010) Phagocytosis and Non-Lytic Exocytosis of Cryptococcus neoformans by and from Acanthamoeba Castellanii. Appl Environ Microbiol.
39. Levitz SM, (1994) Macrophage-Cryptococcus interactions. Immunol Ser 60: 533-43.
40. Steenbergen JN, Nosanchuk JD, Malliaris SD, Casadevall A, (2003) Cryptococcus neoformans virulence is enhanced after growth in the genetically malleable host Dictyostelium discoideum. Infect Immun 71: 4862-72.
41. Steenbergen JN, Shuman HA, Casadevall A, (2001) Cryptococcus neoformans interactions with amoebae suggest an explanation for its virulence and intracellular pathogenic strategy in macrophages. Proc Natl Acad Sci U S A 98: 15245-50.
42. Zaragoza O, Alvarez M, Telzak A, Rivera J, Casadevall A, (2007) The relative susceptibility of mouse strains to pulmonary Cryptococcus neoformans infection is associated with pleiotropic differences in the immune response. Infect Immun 75: 2729-39.
43. Zaragoza O, Chrisman CJ, Castelli MV, Frases S, Cuenca-Estrella M, et al. (2008) Capsule enlargement in Cryptococcus neoformans confers resistance to oxidative stress suggesting a mechanism for intracellular survival. Cell Microbiol 10: 2043-57.
44. Mylonakis E, Casadevall A, Ausubel FM, (2007) Exploiting amoeboid and non-vertebrate animal model systems to study the virulence of human pathogenic fungi. PLoS Pathog 3: e101.
45. Martins-Sousa R, Negrao-Correa D, Bezerra F, Coelho P, (2001) Anesthesia of Biomphalaria spp. (Mollusca, Gastropoda): sodium pentobarbital is the drug of choice. Mem Inst Oswaldo Cruz 96: 391-2.
46. Woods JP, Kersulyte D, Goldman WE, Berg DE, (1993) Fast DNA isolation from Histoplasma capsulatum: methodology for arbitrary primer polymerase chain reaction-based epidemiological and clinical studies. J Clin Microbiol 31: 463-4.
47. Trost A, Graf B, Eucker J, Sezer O, Possinger K, et al. (2004) Identification of clinically relevant yeasts by PCR/RFLP. J Microbiol Methods 56: 201-11.
48. Bryan RA, Zaragoza O, Zhang T, Ortiz G, Casadevall E, et al. (2005) Radiological studies reveal radial differences in the architecture of the polysaccharide capsule of Cryptococcus neoformans. Eukaryot Cell 4: 465-75.
49. Reese AJ, Doering TL, (2003) Cell wall alpha-1,3-glucan is required to anchor the Cryptococcus neoformans capsule. Mol Microbiol 50: 1401-9.
50. McFadden DC, De Jesus M, Casadevall A, (2006) The physical properties of the capsular polysaccharides from Cryptococcus neoformans suggest features for capsule construction. J Biol Chem 281: 1868-75.
51. Viana NB, Rocha MS, Mesquita ON, Mazolli A, Maia Neto PA, et al. (2007) Towards absolute calibration of optical tweezers. Phys Rev E Stat Nonlin Soft Matter Phys 75: 021914.