-
1
-
-
41349116135
-
The eukaryotic genome as an rna machine
-
Amaral, P. P., Dinger, M. E., Mercer, T. R. & Mattick, J. S. The eukaryotic genome as an RNA machine. Science 319, 1787-1789 (2008
-
(2008)
Science
, vol.319
, pp. 1787-1789
-
-
Amaral, P.P.1
Dinger, M.E.2
Mercer, T.R.3
Mattick, J.S.4
-
2
-
-
0037012881
-
Large-scale transcriptional activity in chromosomes 21 and 22
-
Kapranov, P., et al
-
(2002)
Science
, vol.296
, pp. 916-919
-
-
Kapranov, P.1
-
3
-
-
22244442468
-
Examples of the complex architecture of the human transcriptome revealed by race and high-density tiling arrays
-
Kapranov, P., et al. Examples of the complex architecture of the human transcriptome revealed by RACE and high-density tiling arrays. Genome Res. 15, 987-997 (2005
-
(2005)
Genome Res
, vol.15
, pp. 987-997
-
-
Kapranov, P.1
-
4
-
-
33646501507
-
Natural antisense and noncoding rna transcripts as potential drug targets
-
Wahlestedt, C. Natural antisense and noncoding RNA transcripts as potential drug targets. Drug Discov. Today 11, 503-508 (2006
-
(2006)
Drug Discov. Today
, vol.11
, pp. 503-508
-
-
Wahlestedt, C.1
-
5
-
-
0035825662
-
Functional annotation of a full-length mouse cdna collection
-
Kawai, J., et al. Functional annotation of a full-length mouse cDNA collection. Nature 409, 685-690 (2001
-
(2001)
Nature
, vol.409
, pp. 685-690
-
-
Kawai, J.1
-
6
-
-
0142104045
-
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cdnas
-
Okazaki, Y., et al. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature 420, 563-573 (2002
-
(2002)
Nature
, vol.420
, pp. 563-573
-
-
Okazaki, Y.1
-
7
-
-
0037442493
-
The transcriptional activity of human chromosome 22
-
Rinn, J. L., et Al. the Transcriptional Activity of Human Chromosome 22. Genes Dev. 17, 529-540 (2003
-
(2003)
Genes dev
, vol.17
, pp. 529-540
-
-
Rinn, J.L.1
-
8
-
-
80052978224
-
Integrative annotation of human large intergenic noncoding rnas reveals global properties and specific subclasses
-
Cabili, M. N., et al. Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses. Genes Dev. 25, 1915-1927 (2011
-
(2011)
Genes Dev
, vol.25
, pp. 1915-1927
-
-
Cabili, M.N.1
-
9
-
-
79960655760
-
The dna sequence of human chromosome 22
-
Dunham, I., et al. The DNA Sequence of Human Chromosome 22. Nature 402, 489-495 (1999
-
(1999)
Nature
, vol.402
, pp. 489-495
-
-
Dunham, I.1
-
10
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
Lander, E. S., et al. Initial sequencing and analysis of the human genome. Nature 409, 860-921 (2001
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
Lander, E.S.1
-
11
-
-
10244230901
-
A gene map of the human genome
-
Schuler, G. D., et al. A gene map of the human genome. Science 274, 540-546 (1996
-
(1996)
Science
, vol.274
, pp. 540-546
-
-
Schuler, G.D.1
-
12
-
-
34250305146
-
Identification and analysis of functional elements in 1% of the human genome by the encode pilot project
-
ENCODE Project Consortium et a.l.
-
ENCODE Project Consortium et al. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 447, 799-816 (2007
-
(2007)
Nature
, vol.447
, pp. 799-816
-
-
-
13
-
-
84865727393
-
The gencode v7 catalog of human long noncoding rnas: Analysis of their gene structure, evolution, and expression
-
Derrien, T., et al. The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. Genome Res. 22, 1775-1789 (2012
-
(2012)
Genome Res
, vol.22
, pp. 1775-1789
-
-
Derrien, T.1
-
14
-
-
84865760395
-
Gencode: The reference human genome annotation for the encode project
-
Harrow, J., et al. GENCODE: the reference human genome annotation for the ENCODE Project. Genome Res. 22, 1760-1774 (2012
-
(2012)
Genome Res
, vol.22
, pp. 1760-1774
-
-
Harrow, J.1
-
15
-
-
84865790047
-
An integrated encyclopedia of dna elements in the human genome
-
ENCODE Project Consortium
-
ENCODE Project Consortium. An integrated encyclopedia of DNA elements in the human genome. Nature 489, 57-74 (2012
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
-
16
-
-
84879671055
-
Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding rnas
-
Hangauer, M. J., Vaughn, I. W. & McManus, M. T. Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs. PLoS Genet. 9, e1003569 (2013
-
(2013)
PLoS Genet
, vol.9
, pp. e1003569
-
-
Hangauer, M.J.1
Vaughn, I.W.2
McManus, M.T.3
-
17
-
-
70449953975
-
The complex eukaryotic transcriptome: Unexpected pervasive transcription and novel small rnas
-
Jacquier, A. The complex eukaryotic transcriptome: unexpected pervasive transcription and novel small RNAs. Nat. Rev. Genet. 10, 833-844 (2009
-
(2009)
Nat. Rev. Genet
, vol.10
, pp. 833-844
-
-
Jacquier, A.1
-
18
-
-
84865757142
-
Landscape of transcription in human cells
-
Djebali, S., et al. Landscape of transcription in human cells. Nature 489, 101-108 (2012
-
(2012)
Nature
, vol.489
, pp. 101-108
-
-
Djebali, S.1
-
19
-
-
19944376457
-
Global identification of human transcribed sequences with genome tiling arrays
-
Bertone, P., et al. Global identification of human transcribed sequences with genome tiling arrays. Science 306, 2242-2246 (2004
-
(2004)
Science
, vol.306
, pp. 2242-2246
-
-
Bertone, P.1
-
20
-
-
62249133709
-
Chromatin signature reveals over a thousand highly conserved large non-coding rnas in mammals
-
Guttman, M., et al. Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature 458, 223-227 (2009
-
(2009)
Nature
, vol.458
, pp. 223-227
-
-
Guttman, M.1
-
21
-
-
0030026001
-
Requirement for xist in x chromosome inactivation
-
Penny, G. D., Kay, G. F., Sheardown, S. A., Rastan, S. & Brockdorff, N. Requirement for Xist in X chromosome inactivation. Nature 379, 131-137 (1996
-
(1996)
Nature
, vol.379
, pp. 131-137
-
-
Penny, G.D.1
Kay, G.F.2
Sheardown, S.A.3
Rastan, S.4
Brockdorff, N.5
-
22
-
-
38049155825
-
Epigenetic silencing of tumour suppressor gene p15 by its antisense rna
-
Yu, W., et al. Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA. Nature 451, 202-206 (2008
-
(2008)
Nature
, vol.451
, pp. 202-206
-
-
Yu, W.1
-
23
-
-
77951118936
-
Long non-coding rna hotair reprograms chromatin state to promote cancer metastasis
-
Gupta, R. A., et al. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature 464, 1071-1076 (2010
-
(2010)
Nature
, vol.464
, pp. 1071-1076
-
-
Gupta, R.A.1
-
24
-
-
84872135457
-
Control of somatic tissue differentiation by the long non-coding rna tincr
-
Kretz, M., et al. Control of somatic tissue differentiation by the long non-coding RNA TINCR. Nature 493, 231-235 (2013
-
(2013)
Nature
, vol.493
, pp. 231-235
-
-
Kretz, M.1
-
25
-
-
0025012640
-
The product of the h19 gene may function as an rna
-
Brannan, C. I., Dees, E. C., Ingram, R. S. & Tilghman, S. M. The product of the H19 gene may function as an RNA. Mol. Cell. Biol. 10, 28-36 (1990
-
(1990)
Mol. Cell. Biol
, vol.10
, pp. 28-36
-
-
Brannan, C.I.1
Dees, E.C.2
Ingram, R.S.3
Tilghman, S.M.4
-
26
-
-
81055155799
-
Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes
-
Ingolia, N. T., Lareau, L. F. & Weissman, J. S. Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes. Cell 147, 789-802 (2011
-
(2011)
Cell
, vol.147
, pp. 789-802
-
-
Ingolia, N.T.1
Lareau, L.F.2
Weissman, J.S.3
-
27
-
-
84879969127
-
Ribosome profiling provides evidence that large noncoding rnas do not encode proteins
-
Guttman, M., et al. Ribosome profiling provides evidence that large noncoding RNAs do not encode proteins. Cell 154, 240-251 (2013
-
(2013)
Cell
, vol.154
, pp. 240-251
-
-
Guttman, M.1
-
28
-
-
84878865619
-
Ribosome profiling reveals resemblance between long non-coding rnas and 5' leaders of coding rnas
-
Chew, G. L., et al. Ribosome profiling reveals resemblance between long non-coding RNAs and 5' leaders of coding RNAs. Development 140, 2828-2834 (2013
-
(2013)
Development
, vol.140
, pp. 2828-2834
-
-
Chew, G.L.1
-
29
-
-
84899884309
-
Identification of small orfs in vertebrates using ribosome footprinting and evolutionary conservation
-
Bazzini, A. A., et al. Identification of small ORFs in vertebrates using ribosome footprinting and evolutionary conservation. EMBO J. 33, 981-993 (2014
-
(2014)
EMBO J.
, vol.33
, pp. 981-993
-
-
Bazzini, A.A.1
-
30
-
-
84922489184
-
Ribosome profiling reveals pervasive translation outside of annotated protein-coding genes
-
Ingolia, N. T., et al. Ribosome profiling reveals pervasive translation outside of annotated protein-coding genes. Cell Rep. 8, 1365-1379 (2014
-
(2014)
Cell Rep
, vol.8
, pp. 1365-1379
-
-
Ingolia, N.T.1
-
31
-
-
84897446230
-
Enhancer rnas and regulated transcriptional programs
-
Lam, M. T., Li, W., Rosenfeld, M. G. & Glass, C. K. Enhancer RNAs and regulated transcriptional programs. Trends Biochem. Sci. 39, 170-182 (2014
-
(2014)
Trends Biochem. Sci
, vol.39
, pp. 170-182
-
-
Lam, M.T.1
Li, W.2
Rosenfeld, M.G.3
Glass, C.K.4
-
32
-
-
84891711873
-
Extensive localization of long noncoding rnas to the cytosol and mono- and polyribosomal complexes
-
van Heesch, S., et al. Extensive localization of long noncoding RNAs to the cytosol and mono- And polyribosomal complexes. Genome Biol. 15, R6 (2014
-
(2014)
Genome Biol
, vol.15
, pp. R6
-
-
Van Heesch, S.1
-
33
-
-
84893115719
-
Global discovery of erythroid long noncoding rnas reveals novel regulators of red cell maturation
-
Alvarez-Dominguez, J. R., et al. Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation. Blood 123, 570-581 (2014
-
(2014)
Blood
, vol.123
, pp. 570-581
-
-
Alvarez-Dominguez, J.R.1
-
34
-
-
84895908120
-
The evolution of lncrna repertoires and expression patterns in tetrapods
-
Necsulea, A., et al. The evolution of lncRNA repertoires and expression patterns in tetrapods. Nature 505, 635-640 (2014
-
(2014)
Nature
, vol.505
, pp. 635-640
-
-
Necsulea, A.1
-
35
-
-
84897030160
-
The four dimensions of noncoding rna conservation
-
Diederichs, S. The four dimensions of noncoding RNA conservation. Trends Genet. 30, 121-123 (2014
-
(2014)
Trends Genet
, vol.30
, pp. 121-123
-
-
Diederichs, S.1
-
36
-
-
84864629645
-
Rapid turnover of long noncoding rnas and the evolution of gene expression
-
Kutter, C., et al. Rapid turnover of long noncoding RNAs and the evolution of gene expression. PLoS Genet. 8, e1002841 (2012
-
(2012)
PLoS Genet
, vol.8
, pp. e1002841
-
-
Kutter, C.1
-
37
-
-
84455206362
-
Conserved function of lincrnas in vertebrate embryonic development despite rapid sequence evolution
-
Ulitsky, I., Shkumatava, A., Jan, C. H., Sive, H. & Bartel, D. P. Conserved function of lincRNAs in vertebrate embryonic development despite rapid sequence evolution. Cell 147, 1537-1550 (2011
-
(2011)
Cell
, vol.147
, pp. 1537-1550
-
-
Ulitsky, I.1
Shkumatava, A.2
Jan, C.H.3
Sive, H.4
Bartel, D.P.5
-
38
-
-
33745590704
-
Thousands of corresponding human and mouse genomic regions unalignable in primary sequence contain common rna structure
-
Torarinsson, E., Sawera, M., Havgaard, J. H., Fredholm, M. & Gorodkin, J. Thousands of corresponding human and mouse genomic regions unalignable in primary sequence contain common RNA structure. Genome Res. 16, 885-889 (2006
-
(2006)
Genome Res
, vol.16
, pp. 885-889
-
-
Torarinsson, E.1
Sawera, M.2
Havgaard, J.H.3
Fredholm, M.4
Gorodkin, J.5
-
39
-
-
39049142999
-
Comparative genomics beyond sequence-based alignments: Rna structures in the encode regions
-
Torarinsson, E., et al. Comparative genomics beyond sequence-based alignments: RNA structures in the ENCODE regions. Genome Res. 18, 242-251 (2008
-
(2008)
Genome Res
, vol.18
, pp. 242-251
-
-
Torarinsson, E.1
-
40
-
-
84908606605
-
Expanding the functional role of long noncoding rnas
-
Johnsson, P. & Morris, K. V. Expanding the functional role of long noncoding RNAs. Cell Res. 24, 1284-1285 (2014
-
(2014)
Cell Res
, vol.24
, pp. 1284-1285
-
-
Johnsson, P.1
Morris, K.V.2
-
41
-
-
58249088751
-
Micrornas: Target recognition and regulatory functions
-
Bartel, D. P. MicroRNAs: target recognition and regulatory functions. Cell 136, 215-233 (2009
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
42
-
-
84861904178
-
Genome regulation by long noncoding rnas
-
Rinn, J. L. & Chang, H. Y. Genome regulation by long noncoding RNAs. Annu. Rev. Biochem. 81, 145-166 (2012
-
(2012)
Annu. Rev. Biochem
, vol.81
, pp. 145-166
-
-
Rinn, J.L.1
Chang, H.Y.2
-
43
-
-
77954572735
-
Long noncoding rna as modular scaffold of histone modification complexes
-
Tsai, M. C., et al. Long noncoding RNA as modular scaffold of histone modification complexes. Science 329, 689-693 (2010
-
(2010)
Science
, vol.329
, pp. 689-693
-
-
Tsai, M.C.1
-
44
-
-
77956927823
-
The nuclear-retained noncoding rna malat1 regulates alternative splicing by modulating sr splicing factor phosphorylation
-
Tripathi, V., et al. The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. Mol. Cell 39, 925-938 (2010
-
(2010)
Mol. Cell
, vol.39
, pp. 925-938
-
-
Tripathi, V.1
-
45
-
-
34250729138
-
Functional demarcation of active and silent chromatin domains in human hox loci by noncoding rnas
-
Rinn, J. L., et al. Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell 129, 1311-1323 (2007
-
(2007)
Cell
, vol.129
, pp. 1311-1323
-
-
Rinn, J.L.1
-
46
-
-
79953748673
-
A long noncoding rna maintains active chromatin to coordinate homeotic gene expression
-
Wang, K. C., et al. A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression. Nature 472, 120-124 (2011
-
(2011)
Nature
, vol.472
, pp. 120-124
-
-
Wang, K.C.1
-
47
-
-
84893767092
-
Topological organization of multichromosomal regions by the long intergenic noncoding rna firre
-
Hacisuleyman, E., et al. Topological organization of multichromosomal regions by the long intergenic noncoding RNA FIRRE. Nat. Struct. Mol. Biol. 21, 198-206 (2014
-
(2014)
Nat. Struct. Mol. Biol
, vol.21
, pp. 198-206
-
-
Hacisuleyman, E.1
-
48
-
-
80054681545
-
In vivo identification of tumor-suppressive pten cernas in an oncogenic braf-induced mouse model of melanoma
-
Karreth, F. A., et al. In vivo identification of tumor-suppressive PTEN ceRNAs in an oncogenic BRAF-induced mouse model of melanoma. Cell 147, 382-395 (2011
-
(2011)
Cell
, vol.147
, pp. 382-395
-
-
Karreth, F.A.1
-
49
-
-
84865379361
-
Lincrna p21 suppresses target mrna translation
-
Yoon, J. H., et al. LincRNA p21 suppresses target mRNA translation. Mol. Cell 47, 648-655 (2012
-
(2012)
Mol. Cell
, vol.47
, pp. 648-655
-
-
Yoon, J.H.1
-
50
-
-
79951495822
-
Lncrnas transactivate STAU1-mediated mrna decay by duplexing with 3' utrs via Alu elements
-
Gong, C. & Maquat, L. E. lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3' UTRs via Alu elements. Nature 470, 284-288 (2011
-
(2011)
Nature
, vol.470
, pp. 284-288
-
-
Gong, C.1
Maquat, L.E.2
-
51
-
-
84875372911
-
Natural rna circles function as efficient microrna sponges
-
Hansen, T. B., et al. Natural RNA circles function as efficient microRNA sponges. Nature 495, 384-388 (2013
-
(2013)
Nature
, vol.495
, pp. 384-388
-
-
Hansen, T.B.1
-
52
-
-
20244388812
-
Complement factor h variant increases the risk of age-related macular degeneration
-
Haines, J. L., et al. Complement factor H variant increases the risk of age-related macular degeneration. Science 308, 419-421 (2005
-
(2005)
Science
, vol.308
, pp. 419-421
-
-
Haines, J.L.1
-
53
-
-
67249117049
-
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
-
Hindorff, L. A., et al. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc. Natl Acad. Sci. USA 106, 9362-9367 (2009
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 9362-9367
-
-
Hindorff, L.A.1
-
54
-
-
84902161967
-
Dark matter rna illuminates the puzzle of genome-wide association studies
-
St Laurent, G., Vyatkin, Y. & Kapranov, P. Dark matter RNA illuminates the puzzle of genome-wide association studies. BMC Med. 12, 97 (2014
-
(2014)
BMC Med
, vol.12
, Issue.97
-
-
St Laurent, G.1
Vyatkin, Y.2
Kapranov, P.3
-
55
-
-
78650292831
-
The majority of total nuclear-encoded non-ribosomal rna in a human cell is 'dark matter' un-Annotated rna
-
Kapranov, P., et al. The majority of total nuclear-encoded non-ribosomal RNA in a human cell is 'dark matter' un-Annotated RNA. BMC Biol. 8, 149 (2010
-
(2010)
BMC Biol
, vol.8
, Issue.149
-
-
Kapranov, P.1
-
56
-
-
84873489136
-
Human disease-Associated genetic variation impacts large intergenic non-coding rna expression
-
Kumar, V., et al. Human disease-Associated genetic variation impacts large intergenic non-coding RNA expression. PLoS Genet. 9, e1003201 (2013
-
(2013)
PLoS Genet
, vol.9
, pp. e1003201
-
-
Kumar, V.1
-
57
-
-
84876125829
-
Lncrnadisease: A database for long non coding rna-Associated diseases
-
Chen, G., et al. LncRNADisease: a database for long non coding RNA-Associated diseases. Nucleic Acids Res. 41, D983-D986 (2013
-
(2013)
Nucleic Acids Res
, vol.41
, pp. D983-D986
-
-
Chen, G.1
-
58
-
-
84908318087
-
Genetic variation in the non-coding genome: Involvement of micro-rnas and long non-coding rnas in disease
-
Hrdlickova, B., de Almeida, R. C., Borek, Z. & Withoff, S. Genetic variation in the non-coding genome: Involvement of micro-RNAs and long non-coding RNAs in disease. Biochim. Biophys. Acta 1842, 1910-1922 (2014
-
(2014)
Biochim. Biophys. Acta
, vol.1842
, pp. 1910-1922
-
-
Hrdlickova, B.1
De Almeida, R.C.2
Borek, Z.3
Withoff, S.4
-
59
-
-
84901608759
-
Lincsnp: A database of linking disease-Associated snps to human large intergenic non-coding rnas
-
Ning, S., et al. LincSNP: a database of linking disease-Associated SNPs to human large intergenic non-coding RNAs. BMC Bioinformatics 15, 152 (2014
-
(2014)
BMC Bioinformatics
, vol.15
, pp. 152
-
-
Ning, S.1
-
60
-
-
84867070330
-
Human β cell transcriptome analysis uncovers lncrnas that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes
-
Moran, I., et al. Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes. Cell Metab. 16, 435-448 (2012
-
(2012)
Cell Metab
, vol.16
, pp. 435-448
-
-
Morán, I.1
-
61
-
-
33745268851
-
Mutations in glis3 are responsible for a rare syndrome with neonatal diabetes mellitus and congenital hypothyroidism
-
Senée, V., et al. Mutations in GLIS3 are responsible for a rare syndrome with neonatal diabetes mellitus and congenital hypothyroidism. Nat. Genet. 38, 682-687 (2006
-
(2006)
Nat. Genet
, vol.38
, pp. 682-687
-
-
Senée, V.1
-
62
-
-
84655162045
-
Meta-Analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east asians
-
Cho, Y. S., et al. Meta-Analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in East Asians. Nat. Genet. 44, 67-72 (2012
-
(2012)
Nat. Genet
, vol.44
, pp. 67-72
-
-
Cho, Y.S.1
-
63
-
-
84878507398
-
Glis3, a susceptibility gene for type 1 and type 2 diabetes, modulates pancreatic β cell apoptosis via regulation of a splice variant of the bh3-only protein bim
-
Nogueira, T. C., et al. GLIS3, a susceptibility gene for type 1 and type 2 diabetes, modulates pancreatic β cell apoptosis via regulation of a splice variant of the BH3-only protein Bim. PLoS Genet. 9, e1003532 (2013
-
(2013)
PLoS Genet
, vol.9
, pp. e1003532
-
-
Nogueira, T.C.1
-
64
-
-
84907222786
-
Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism
-
Fadista, J., et al. Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism. Proc. Natl Acad. Sci. USA 111, 13924-13929 (2014
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. 13924-13929
-
-
Fadista, J.1
-
65
-
-
84860599353
-
Transgenerational glucose intolerance with igf2/h19 epigenetic alterations in mouse islet induced by intrauterine hyperglycemia
-
Ding, G. L., et al. Transgenerational glucose intolerance with Igf2/H19 epigenetic alterations in mouse islet induced by intrauterine hyperglycemia. Diabetes 61, 1133-1142 (2012
-
(2012)
Diabetes
, vol.61
, pp. 1133-1142
-
-
Ding, G.L.1
-
66
-
-
34249888775
-
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
-
Diabetes Genetics Initiative of Broad Institute of Harvard and MIT et a.l.
-
Diabetes Genetics Initiative of Broad Institute of Harvard and MIT et al. Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 316, 1331-1336 (2007
-
(2007)
Science
, vol.316
, pp. 1331-1336
-
-
-
67
-
-
34249895023
-
Replication of genome-wide association signals in uk samples reveals risk loci for type 2 diabetes
-
Zeggini, E., et al. Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 316, 1336-1341 (2007
-
(2007)
Science
, vol.316
, pp. 1336-1341
-
-
Zeggini, E.1
-
68
-
-
34249885875
-
A genome-wide association study of type 2 diabetes in finns detects multiple susceptibility variants
-
Scott, L. J., et al. A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 316, 1341-1345 (2007
-
(2007)
Science
, vol.316
, pp. 1341-1345
-
-
Scott, L.J.1
-
69
-
-
79551623370
-
Anril a long, noncoding rna, is an unexpected major hotspot in gwas
-
Pasmant, E., Sabbagh, A., Vidaud, M. & Bièche, I. ANRIL, a long, noncoding RNA, is an unexpected major hotspot in GWAS. FASEB J. 25, 444-448 (2011
-
(2011)
FASEB J
, vol.25
, pp. 444-448
-
-
Pasmant, E.1
Sabbagh, A.2
Vidaud, M.3
Bièche, I.4
-
70
-
-
77953096072
-
Molecular interplay of the noncoding rna anril and methylated histone h3 lysine 27 by polycomb cbx7 in transcriptional silencing of ink4a
-
Yap, K. L., et al. Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a. Mol. Cell 38, 662-674 (2010
-
(2010)
Mol Cell
, vol.38
, pp. 662-674
-
-
Yap, K.L.1
-
71
-
-
33749187810
-
P16ink4a induces an age-dependent decline in islet regenerative potential
-
Krishnamurthy, J., et al. p16INK4a induces an age-dependent decline in islet regenerative potential. Nature 443, 453-457 (2006
-
(2006)
Nature
, vol.443
, pp. 453-457
-
-
Krishnamurthy, J.1
-
72
-
-
35948950608
-
Altered regulation of the PINK1 locus: A link between type 2 diabetes and neurodegeneration?
-
Scheele, C., et al. Altered Regulation of the PINK1 Locus: A Link between Type 2 Diabetes and Neurodegeneration?. FASEB J. 21, 3653-3665 (2007
-
(2007)
FASEB J
, vol.21
, pp. 3653-3665
-
-
Scheele, C.1
-
73
-
-
77954143522
-
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
-
Voight, B. F., et al. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat. Genet. 42, 579-589 (2010
-
(2010)
Nat. Genet
, vol.42
, pp. 579-589
-
-
Voight, B.F.1
-
74
-
-
73349115848
-
The imprinted dlk1-meg3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes
-
Wallace, C., et al. The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes. Nat. Genet. 42, 68-71 (2010
-
(2010)
Nat. Genet
, vol.42
, pp. 68-71
-
-
Wallace, C.1
-
75
-
-
80053238905
-
Silencing of the imprinted dlk1-meg3 locus in human clinically nonfunctioning pituitary adenomas
-
Cheunsuchon, P., et al. Silencing of the imprinted DLK1-MEG3 locus in human clinically nonfunctioning pituitary adenomas. Am. J. Pathol. 179, 2120-2130 (2011
-
(2011)
Am. J. Pathol
, vol.179
, pp. 2120-2130
-
-
Cheunsuchon, P.1
-
77
-
-
2442597244
-
The steroid receptor rna activator is the first functional rna encoding a protein
-
Chooniedass-Kothari, S., et al. The steroid receptor RNA activator is the first functional RNA encoding a protein. FEBS Lett. 566, 43-47 (2004
-
(2004)
FEBS Lett
, vol.566
, pp. 43-47
-
-
Chooniedass-Kothari, S.1
-
78
-
-
84874500772
-
Long noncoding rnas regulate adipogenesis
-
Sun, L., et al. Long noncoding RNAs regulate adipogenesis. Proc. Natl Acad. Sci. USA 110, 3387-3392 (2013
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 3387-3392
-
-
Sun, L.1
-
79
-
-
80053060584
-
Effect of peucedanum japonicum thunb on the expression of obesity-related genes in mice on a high-fat diet
-
Nukitrangsan, N., et al. Effect of Peucedanum japonicum Thunb on the expression of obesity-related genes in mice on a high-fat diet. J. Oleo Sci. 60, 527-536 (2011
-
(2011)
J. Oleo Sci
, vol.60
, pp. 527-536
-
-
Nukitrangsan, N.1
-
80
-
-
70350539531
-
Atf4 regulates obesity, glucose homeostasis, and energy expenditure
-
Seo, J., et al. Atf4 regulates obesity, glucose homeostasis, and energy expenditure. Diabetes 58, 2565-2573 (2009
-
(2009)
Diabetes
, vol.58
, pp. 2565-2573
-
-
Seo, J.1
-
81
-
-
11244318158
-
The malate-Aspartate nadh shuttle member aralar1 determines glucose metabolic fate, mitochondrial activity, and insulin secretion in β cells
-
Rubi, B., del Arco, A., Bartley, C., Satrustegui, J. & Maechler, P. The malate-Aspartate NADH shuttle member Aralar1 determines glucose metabolic fate, mitochondrial activity, and insulin secretion in β cells. J. Biol. Chem. 279, 55659-55666 (2004
-
(2004)
J. Biol. Chem
, vol.279
, pp. 55659-55666
-
-
Rubi, B.1
Del Arco, A.2
Bartley, C.3
Satrustegui, J.4
Maechler, P.5
-
82
-
-
79251544878
-
Mir 130 suppresses adipogenesis by inhibiting peroxisome proliferator-Activated receptor γ expression
-
Lee, E. K., et al. miR 130 suppresses adipogenesis by inhibiting peroxisome proliferator-Activated receptor γ expression. Mol. Cell. Biol. 31, 626-638 (2011
-
(2011)
Mol. Cell. Biol
, vol.31
, pp. 626-638
-
-
Lee, E.K.1
-
83
-
-
84905499238
-
A long noncoding rna transcriptional regulatory circuit drives thermogenic adipocyte differentiation
-
Zhao, X. Y., Li, S., Wang, G. X., Yu, Q. & Lin, J. D. A long noncoding RNA transcriptional regulatory circuit drives thermogenic adipocyte differentiation. Mol. Cell 55, 372-382 (2014
-
(2014)
Mol. Cell
, vol.55
, pp. 372-382
-
-
Zhao, X.Y.1
Li, S.2
Wang, G.X.3
Yu, Q.4
Lin, J.D.5
-
84
-
-
0028865142
-
Expression of the mitochondrial uncoupling protein gene from the ap2 gene promoter prevents genetic obesity
-
Kopecky, J., Clarke, G., Enerbäck, S., Spiegelman, B. & Kozak, L. P. Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity. J. Clin. Invest. 96, 2914-2923 (1995
-
(1995)
J. Clin. Invest
, vol.96
, pp. 2914-2923
-
-
Kopecky, J.1
Clarke, G.2
Enerbäck, S.3
Spiegelman, B.4
Kozak, L.P.5
-
85
-
-
63049123701
-
Dax 1 and steroid receptor rna activator (sra) function as transcriptional coactivators for steroidogenic factor 1 in steroidogenesis
-
Xu, B., et al. Dax 1 and steroid receptor RNA activator (SRA) function as transcriptional coactivators for steroidogenic factor 1 in steroidogenesis. Mol. Cell. Biol. 29, 1719-1734 (2009
-
(2009)
Mol. Cell. Biol
, vol.29
, pp. 1719-1734
-
-
Xu, B.1
-
86
-
-
0034751523
-
Persistent changes in gene expression induced by estrogen and progesterone in the rat mammary gland
-
Ginger, M. R., Gonzalez-Rimbau, M. F., Gay, J. P. & Rosen, J. M. Persistent changes in gene expression induced by estrogen and progesterone in the rat mammary gland. Mol. Endocrinol. 15, 1993-2009 (2001
-
(2001)
Mol. Endocrinol
, vol.15
, pp. 1993-2009
-
-
Ginger, M.R.1
Gonzalez-Rimbau, M.F.2
Gay, J.P.3
Rosen, J.M.4
-
87
-
-
33645823589
-
A noncoding rna is a potential marker of cell fate during mammary gland development
-
Ginger, M. R., et al. A noncoding RNA is a potential marker of cell fate during mammary gland development. Proc. Natl Acad. Sci. USA 103, 5781-5786 (2006
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 5781-5786
-
-
Ginger, M.R.1
-
88
-
-
84864607981
-
Pregnancy-induced noncoding rna (pinc) associates with polycomb repressive complex 2 and regulates mammary epithelial differentiation
-
Shore, A. N., et al. Pregnancy-induced noncoding RNA (PINC) associates with polycomb repressive complex 2 and regulates mammary epithelial differentiation. PLoS Genet. 8, e1002840 (2012
-
(2012)
PLoS Genet
, vol.8
, pp. e1002840
-
-
Shore, A.N.1
-
89
-
-
79955005458
-
Snord-host rna zfas1 is a regulator of mammary development and a potential marker for breast cancer
-
Askarian-Amiri, M. E., et al. SNORD-host RNA Zfas1 is a regulator of mammary development and a potential marker for breast cancer. RNA 17, 878-891 (2011
-
(2011)
RNA
, vol.17
, pp. 878-891
-
-
Askarian-Amiri, M.E.1
-
90
-
-
84865188054
-
Circadian changes in long noncoding rnas in the pineal gland
-
Coon, S. L., et al. Circadian changes in long noncoding RNAs in the pineal gland. Proc. Natl Acad. Sci. USA 109, 13319-13324 (2012
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 13319-13324
-
-
Coon, S.L.1
-
91
-
-
79955836460
-
A rapid, extensive, and transient transcriptional response to estrogen signaling in breast cancer cells
-
Hah, N., et al. A rapid, extensive, and transient transcriptional response to estrogen signaling in breast cancer cells. Cell 145, 622-634 (2011
-
(2011)
Cell
, vol.145
, pp. 622-634
-
-
Hah, N.1
-
92
-
-
84879695128
-
Functional roles of enhancer rnas for oestrogen-dependent transcriptional activation
-
Li, W., et al. Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation. Nature 498, 516-520 (2013
-
(2013)
Nature
, vol.498
, pp. 516-520
-
-
Li, W.1
-
93
-
-
84883762956
-
Antisense transcript long noncoding rna (lncrna) hotair is transcriptionally induced by estradiol
-
Bhan, A., et al. Antisense transcript long noncoding RNA (lncRNA) HOTAIR is transcriptionally induced by estradiol. J. Mol. Biol. 425, 3707-3722 (2013
-
(2013)
J. Mol. Biol
, vol.425
, pp. 3707-3722
-
-
Bhan, A.1
-
94
-
-
0035339146
-
Sharp, an inducible cofactor that integrates nuclear receptor repression and activation
-
Shi, Y., et al. Sharp, an inducible cofactor that integrates nuclear receptor repression and activation. Genes Dev. 15, 1140-1151 (2001
-
(2001)
Genes Dev
, vol.15
, pp. 1140-1151
-
-
Shi, Y.1
-
95
-
-
33744541544
-
Slirp, a small sra binding protein, is a nuclear receptor corepressor
-
Hatchell, E. C., et al. SLIRP, a small SRA binding protein, is a nuclear receptor corepressor. Mol. Cell 22, 657-668 (2006
-
(2006)
Mol. Cell
, vol.22
, pp. 657-668
-
-
Hatchell, E.C.1
-
96
-
-
77952952164
-
Identification of long stress-induced non-coding transcripts that have altered expression in cancer
-
Silva, J. M., et al. Identification of long stress-induced non-coding transcripts that have altered expression in cancer. Genomics 95, 355-362 (2010
-
(2010)
Genomics
, vol.95
, pp. 355-362
-
-
Silva, J.M.1
-
97
-
-
79956095811
-
Lsinct5 is over expressed in breast and ovarian cancer and affects cellular proliferation
-
Silva, J. M., Boczek, N. J., Berres, M. W., Ma, X. & Smith, D. I. LSINCT5 is over expressed in breast and ovarian cancer and affects cellular proliferation. RNA Biol. 8, 496-505 (2011
-
(2011)
RNA Biol
, vol.8
, pp. 496-505
-
-
Silva, J.M.1
Boczek, N.J.2
Berres, M.W.3
Ma, X.4
Smith, D.I.5
-
98
-
-
12944252955
-
Pcgem1, a prostate-specific gene, is overexpressed in prostate cancer
-
Srikantan, V., et al. PCGEM1, a prostate-specific gene, is overexpressed in prostate cancer. Proc. Natl Acad. Sci. USA 97, 12216-12221 (2000
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 12216-12221
-
-
Srikantan, V.1
-
99
-
-
78650200618
-
Association of a novel long non-coding rna in 8q24 with prostate cancer susceptibility
-
Chung, S., et al. Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility. Cancer Sci. 102, 245-252 (2011
-
(2011)
Cancer Sci
, vol.102
, pp. 245-252
-
-
Chung, S.1
-
100
-
-
84883132550
-
Lncrna-dependent mechanisms of androgen receptor regulated gene activation programs
-
Yang, L., et al. lncRNA-dependent mechanisms of androgen receptor regulated gene activation programs. Nature 500, 598-602 (2013
-
(2013)
Nature
, vol.500
, pp. 598-602
-
-
Yang, L.1
-
101
-
-
79961202865
-
Transcriptome sequencing across a prostate cancer cohort identifies pcat 1, an unannotated lincrna implicated in disease progression
-
Prensner, J. R., et al. Transcriptome sequencing across a prostate cancer cohort identifies PCAT 1, an unannotated lincRNA implicated in disease progression. Nat. Biotechnol. 29, 742-749 (2011
-
(2011)
Nat. Biotechnol
, vol.29
, pp. 742-749
-
-
Prensner, J.R.1
-
102
-
-
79551646237
-
Integration of cap analysis of gene expression and chromatin immunoprecipitation analysis on array reveals genome-wide androgen receptor signaling in prostate cancer cells
-
Takayama, K., et al. Integration of cap analysis of gene expression and chromatin immunoprecipitation analysis on array reveals genome-wide androgen receptor signaling in prostate cancer cells. Oncogene 30, 619-630 (2011
-
(2011)
Oncogene
, vol.30
, pp. 619-630
-
-
Takayama, K.1
-
103
-
-
84879462680
-
Androgen-responsive long noncoding rna ctbp1-As promotes prostate cancer
-
Takayama, K. I., et al. Androgen-responsive long noncoding RNA CTBP1-AS promotes prostate cancer. EMBO J. 32, 1665-1680 (2013
-
(2013)
EMBO J.
, vol.32
, pp. 1665-1680
-
-
Takayama, K.I.1
-
104
-
-
34548304069
-
Activation of p53 by meg3 non-coding rna
-
Zhou, Y., et al. Activation of p53 by MEG3 non-coding RNA. J. Biol. Chem. 282, 24731-24742 (2007
-
(2007)
J. Biol. Chem
, vol.282
, pp. 24731-24742
-
-
Zhou, Y.1
-
105
-
-
63449092713
-
Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in european populations
-
Gudmundsson, J., et al. Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations. Nat. Genet. 41, 460-464 (2009
-
(2009)
Nat. Genet
, vol.41
, pp. 460-464
-
-
Gudmundsson, J.1
-
106
-
-
84862777075
-
Discovery of common variants associated with low tsh levels and thyroid cancer risk
-
Gudmundsson, J., et al. Discovery of common variants associated with low TSH levels and thyroid cancer risk. Nat. Genet. 44, 319-322 (2012
-
(2012)
Nat. Genet
, vol.44
, pp. 319-322
-
-
Gudmundsson, J.1
-
107
-
-
84861862859
-
The polymorphism rs944289 predisposes to papillary thyroid carcinoma through a large intergenic noncoding rna gene of tumor suppressor type
-
Jendrzejewski, J., et al. The polymorphism rs944289 predisposes to papillary thyroid carcinoma through a large intergenic noncoding RNA gene of tumor suppressor type. Proc. Natl Acad. Sci. USA 109, 8646-8651 (2012
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 8646-8651
-
-
Jendrzejewski, J.1
-
108
-
-
34547093157
-
Identification of a novel noncoding rna gene, nama, that is downregulated in papillary thyroid carcinoma with braf mutation and associated with growth arrest
-
Yoon, H., et al. Identification of a novel noncoding RNA gene, NAMA, that is downregulated in papillary thyroid carcinoma with BRAF mutation and associated with growth arrest. Int. J. Cancer 121, 767-775 (2007
-
(2007)
Int. J. Cancer
, vol.121
, pp. 767-775
-
-
Yoon, H.1
-
109
-
-
58349088314
-
A susceptibility locus for papillary thyroid carcinoma on chromosome 8q24
-
He, H., et al. A Susceptibility Locus for Papillary Thyroid arcinoma on Chromosome 8q24. Cancer Res. 69, 625-631 (2009
-
(2009)
Cancer res
, vol.69
, pp. 625-631
-
-
He, H.1
-
110
-
-
77951638287
-
Noncoding rna gas5 is a growth arrest- and starvation-Associated repressor of the glucocorticoid receptor
-
ra8
-
Kino, T., Hurt, D. E., Ichijo, T., Nader, N. & Chrousos, G. P. Noncoding RNA gas5 is a growth arrest- And starvation-Associated repressor of the glucocorticoid receptor. Sci. Signal. 3, ra8 (2010
-
(2010)
Sci. Signal
, vol.3
-
-
Kino, T.1
Hurt, D.E.2
Ichijo, T.3
Nader, N.4
Chrousos, G.P.5
-
111
-
-
84893427735
-
In vivo genome-wide profiling of rna secondary structure reveals novel regulatory features
-
Ding, Y., et al. In vivo genome-wide profiling of RNA secondary structure reveals novel regulatory features. Nature 505, 696-700 (2014
-
(2014)
Nature
, vol.505
, pp. 696-700
-
-
Ding, Y.1
-
112
-
-
84893351549
-
Genome-wide probing of rna structure reveals active unfolding of mrna structures in vivo
-
Rouskin, S., Zubradt, M., Washietl, S., Kellis, M. & Weissman, J. S. Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo. Nature 505, 701-705 (2014
-
(2014)
Nature
, vol.505
, pp. 701-705
-
-
Rouskin, S.1
Zubradt, M.2
Washietl, S.3
Kellis, M.4
Weissman, J.S.5
-
113
-
-
84893358533
-
Landscape and variation of rna secondary structure across the human transcriptome
-
Wan, Y., et al. Landscape and variation of RNA secondary structure across the human transcriptome. Nature 505, 706-709 (2014
-
(2014)
Nature
, vol.505
, pp. 706-709
-
-
Wan, Y.1
-
114
-
-
84900001797
-
Noncoding rnas in endocrine malignancy
-
Kentwell, J., Gundara, J. S. & Sidhu, S. B. Noncoding RNAs in endocrine malignancy. Oncologist 19, 483-491 (2014
-
(2014)
Oncologist
, vol.19
, pp. 483-491
-
-
Kentwell, J.1
Gundara, J.S.2
Sidhu, S.B.3
-
115
-
-
84890568010
-
Analysis of the canine brain transcriptome with an emphasis on the hypothalamus and cerebral cortex
-
Roy, M., et al. Analysis of the canine brain transcriptome with an emphasis on the hypothalamus and cerebral cortex. Mamm. Genome 24, 484-499 (2013
-
(2013)
Mamm. Genome
, vol.24
, pp. 484-499
-
-
Roy, M.1
-
116
-
-
84875890253
-
Hotair is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer
-
Kim, K., et al. HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer. Oncogene 32, 1616-1625 (2013
-
(2013)
Oncogene
, vol.32
, pp. 1616-1625
-
-
Kim, K.1
-
117
-
-
78649955414
-
Multiple roles for the non-coding rna sra in regulation of adipogenesis and insulin sensitivity
-
Xu, B., et al. Multiple roles for the non-coding RNA SRA in regulation of adipogenesis and insulin sensitivity. PLoS ONE 5, e14199 (2010
-
(2010)
PLoS ONE
, vol.5
, pp. e14199
-
-
Xu, B.1
-
118
-
-
84900430009
-
Sra gene knockout protects against diet-induced obesity and improves glucose tolerance
-
Liu, S., et al. SRA gene knockout protects against diet-induced obesity and improves glucose tolerance. J. Biol. Chem. 289, 13000-13009 (2014
-
(2014)
J. Biol. Chem
, vol.289
, pp. 13000-13009
-
-
Liu, S.1
-
119
-
-
84885404224
-
Long non-coding rna expression profiling of mouse testis during postnatal development
-
Sun, J., Lin, Y. & Wu, J. Long non-coding RNA expression profiling of mouse testis during postnatal development. PLoS ONE 8, e75750 (2013
-
(2013)
PLoS ONE
, vol.8
, pp. e75750
-
-
Sun, J.1
Lin, Y.2
Wu, J.3
-
120
-
-
84890000516
-
Association between polymorphisms in long non-coding rna prncr1 in 8q24 and risk of colorectal cancer
-
Li, L., et al. Association between polymorphisms in long non-coding RNA PRNCR1 in 8q24 and risk of colorectal cancer. J. Exp. Clin. Cancer Res. 32, 104 (2013
-
(2013)
J. Exp. Clin. Cancer Res
, vol.32
, pp. 104
-
-
Li, L.1
|