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Volumn 306, Issue 5705, 2004, Pages 2242-2246

Global identification of human transcribed sequences with genome tiling arrays

Author keywords

[No Author keywords available]

Indexed keywords

DNA; PROTEINS; RNA; TISSUE;

EID: 19944376457     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1103388     Document Type: Article
Times cited : (897)

References (26)
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    • Materials and methods are available as supporting material on Science Online. Additional information can be found at http://transcriptome.gersteinlab. org. Experimental data and associated microarray designs are available in the NCBI Gene Expression Omnibus (GEO) under series GSE1904, sample records CSM34073 to CSM34213, and platform records CPL1539 to CPL1673.
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    • data not shown
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    • note
    • Each probe is assigned a value of 1 if its fluorescence intensity is greater than the median intensity of all probes on the array, and O otherwise. For a given gene, the expected count of 1's within annotated exons follows a binomial distribution; an unusually high count of 1's therefore yields low P values (sign test). Genes having P values < 0.05 were regarded as demonstrating positive hybridization.
  • 18
    • 11144301503 scopus 로고    scopus 로고
    • note
    • Polyadenylation signals are required to appear downstream of the 15th nucleotide of the 3′ oligonucleotide in the transcribed region. An additional 51 (46 + 5) downstream nucleotides are included in the calculation to ensure full coverage of the sequence.
  • 21
  • 25
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    • 11144253003 scopus 로고    scopus 로고
    • note
    • This work was supported by NIH grant P50 HG02357.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.