메뉴 건너뛰기




Volumn 6, Issue , 2015, Pages

Site- and allele-specific polycomb dysregulation in T-cell leukaemia

(28)  Navarro, Jean Marc a,b   Touzart, Aurore c   Pradel, Lydie C a,b,k   Loosveld, Marie a,b,d   Koubi, Myriam e   Fenouil, Romain a,b   Le Noir, Sandrine c   Maqbool, Muhammad Ahmad a,b,l   Morgado, Ester a,b   Gregoire, Claude a,b   Jaeger, Sebastien a,b   Mamessier, Emilie a,b   Pignon, Charles a,b   Hacein Bey Abina, Salima f   Malissen, Bernard a,b   Gut, Marta g   Gut, Ivo G g   Dombret, Hervé h   MacIntyre, Elizabeth A c   Howe, Steven J i   more..

b INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H3; TRANSCRIPTION FACTOR TAL1; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; DNA BINDING PROTEIN; HISTONE; HOMEODOMAIN PROTEIN; NUCLEAR PROTEIN; ONCOPROTEIN; POLYCOMB GROUP PROTEIN; RAG-1 PROTEIN; RAG2 PROTEIN, HUMAN; TAL1 PROTEIN, HUMAN;

EID: 84923096527     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7094     Document Type: Article
Times cited : (44)

References (44)
  • 1
    • 66149113692 scopus 로고    scopus 로고
    • Molecular genetics of acute lymphoblastic leukemia
    • Teitell, M. A. & Pandolfi, P. P. Molecular genetics of acute lymphoblastic leukemia. Annu. Rev. Pathol. 4, 175-198 (2009).
    • (2009) Annu. Rev. Pathol. , vol.4 , pp. 175-198
    • Teitell, M.A.1    Pandolfi, P.P.2
  • 2
    • 52749085175 scopus 로고    scopus 로고
    • Molecular-genetic insights in paediatric T-cell acute lymphoblastic leukaemia
    • Van Vlierberghe, P., Pieters, R., Beverloo, H. B. & Meijerink, J. P. Molecular-genetic insights in paediatric T-cell acute lymphoblastic leukaemia. Br. J. Haematol. 143, 153-168 (2008).
    • (2008) Br. J. Haematol. , vol.143 , pp. 153-168
    • Van Vlierberghe, P.1    Pieters, R.2    Beverloo, H.B.3    Meijerink, J.P.4
  • 3
    • 84865109759 scopus 로고    scopus 로고
    • Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia
    • Sanda, T. et al. Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia. Cancer Cell 22, 209-221 (2012).
    • (2012) Cancer Cell , vol.22 , pp. 209-221
    • Sanda, T.1
  • 4
    • 0027439641 scopus 로고
    • Expression of tal-1 and GATA-binding proteins during human hematopoiesis
    • Mouthon, M. A. et al. Expression of tal-1 and GATA-binding proteins during human hematopoiesis. Blood 81, 647-655 (1993).
    • (1993) Blood , vol.81 , pp. 647-655
    • Mouthon, M.A.1
  • 5
    • 0034252945 scopus 로고    scopus 로고
    • SCL and LMO1 alter thymocyte differentiation: Inhibition of E2A-HEB function and pre-T alpha chain expression
    • Herblot, S., Steff, A. M., Hugo, P., Aplan, P. D. & Hoang, T. SCL and LMO1 alter thymocyte differentiation: inhibition of E2A-HEB function and pre-T alpha chain expression. Nat. Immunol. 1, 138-144 (2000).
    • (2000) Nat. Immunol. , vol.1 , pp. 138-144
    • Herblot, S.1    Steff, A.M.2    Hugo, P.3    Aplan, P.D.4    Hoang, T.5
  • 6
    • 84859157183 scopus 로고    scopus 로고
    • Dynamic transformations of genome-wide epigenetic marking and transcriptional control establish T cell identity
    • Zhang, J. A., Mortazavi, A., Williams, B. A., Wold, B. J. & Rothenberg, E. V. Dynamic transformations of genome-wide epigenetic marking and transcriptional control establish T cell identity. Cell 149, 467-482 (2012).
    • (2012) Cell , vol.149 , pp. 467-482
    • Zhang, J.A.1    Mortazavi, A.2    Williams, B.A.3    Wold, B.J.4    Rothenberg, E.V.5
  • 7
    • 1442307956 scopus 로고    scopus 로고
    • Biallelic transcriptional activation of oncogenic transcription factors in T-cell acute lymphoblastic leukemia
    • Ferrando, A. A. et al. Biallelic transcriptional activation of oncogenic transcription factors in T-cell acute lymphoblastic leukemia. Blood 103, 1909-1911 (2004).
    • (2004) Blood , vol.103 , pp. 1909-1911
    • Ferrando, A.A.1
  • 8
    • 0032555758 scopus 로고    scopus 로고
    • DNA transposition by the RAG1 and RAG2 proteins: A possible source of oncogenic translocations
    • Hiom, K., Melek, M. & Gellert, M. DNA transposition by the RAG1 and RAG2 proteins: a possible source of oncogenic translocations. Cell 94, 463-470 (1998).
    • (1998) Cell , vol.94 , pp. 463-470
    • Hiom, K.1    Melek, M.2    Gellert, M.3
  • 9
    • 0032551829 scopus 로고    scopus 로고
    • Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system
    • Agrawal, A., Eastman, Q. M. & Schatz, D. G. Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system. Nature 394, 744-751 (1998).
    • (1998) Nature , vol.394 , pp. 744-751
    • Agrawal, A.1    Eastman, Q.M.2    Schatz, D.G.3
  • 10
    • 79961022267 scopus 로고    scopus 로고
    • Transcription initiation platforms and GTF recruitment at tissue-specific enhancers and promoters
    • Koch, F. et al. Transcription initiation platforms and GTF recruitment at tissue-specific enhancers and promoters. Nat. Struct. Mol. Biol. 18, 956-963 (2011).
    • (2011) Nat. Struct. Mol. Biol. , vol.18 , pp. 956-963
    • Koch, F.1
  • 11
    • 60149095014 scopus 로고    scopus 로고
    • Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains
    • Cuddapah, S. et al. Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains. Genome Res. 19, 24-32 (2009).
    • (2009) Genome Res. , vol.19 , pp. 24-32
    • Cuddapah, S.1
  • 12
    • 58049191558 scopus 로고    scopus 로고
    • Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation
    • Cui, K. et al. Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation. Cell Stem Cell 4, 80-93 (2009).
    • (2009) Cell Stem Cell , vol.4 , pp. 80-93
    • Cui, K.1
  • 13
    • 84894629080 scopus 로고    scopus 로고
    • Chromatin looping defines expression of TAL1, its flanking genes and regulation in T-ALL
    • Zhou, Y. et al. Chromatin looping defines expression of TAL1, its flanking genes and regulation in T-ALL. Blood 122, 4199-4209 (2013).
    • (2013) Blood , vol.122 , pp. 4199-4209
    • Zhou, Y.1
  • 14
    • 84870573126 scopus 로고    scopus 로고
    • EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations
    • McCabe, M. T. et al. EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations. Nature 492, 108-112 (2012).
    • (2012) Nature , vol.492 , pp. 108-112
    • McCabe, M.T.1
  • 15
    • 80054032532 scopus 로고    scopus 로고
    • TAL1/SCL is downregulated upon histone deacetylase inhibition in T-cell acute lymphoblastic leukemia cells
    • Cardoso, B. A. et al. TAL1/SCL is downregulated upon histone deacetylase inhibition in T-cell acute lymphoblastic leukemia cells. Leukaemia 25, 1578-1586 (2011).
    • (2011) Leukaemia , vol.25 , pp. 1578-1586
    • Cardoso, B.A.1
  • 16
    • 51349158298 scopus 로고    scopus 로고
    • Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients
    • Howe, S. J. et al. Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients. J. Clin. Invest. 118, 3143-3150 (2008).
    • (2008) J. Clin. Invest. , vol.118 , pp. 3143-3150
    • Howe, S.J.1
  • 17
    • 3242883717 scopus 로고    scopus 로고
    • V(D)J recombination: How to tame a transposase
    • Brandt, V. L. & Roth, D. B. V(D)J recombination: how to tame a transposase. Immunol. Rev. 200, 249-260 (2004).
    • (2004) Immunol. Rev. , vol.200 , pp. 249-260
    • Brandt, V.L.1    Roth, D.B.2
  • 18
    • 34548009617 scopus 로고    scopus 로고
    • The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL), the translocation defining a new T-ALL subtype in very young children
    • Clappier, E. et al. The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL), the translocation defining a new T-ALL subtype in very young children. Blood 110, 1251-1261 (2007).
    • (2007) Blood , vol.110 , pp. 1251-1261
    • Clappier, E.1
  • 19
    • 84856747744 scopus 로고    scopus 로고
    • Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia
    • Ntziachristos, P. et al. Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia. Nat Med. 18, 298-301 (2012).
    • (2012) Nat Med. , vol.18 , pp. 298-301
    • Ntziachristos, P.1
  • 20
    • 84859295400 scopus 로고    scopus 로고
    • A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia
    • Simon, C. et al. A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia. Genes Dev. (2012).
    • (2012) Genes Dev.
    • Simon, C.1
  • 21
    • 84862907593 scopus 로고    scopus 로고
    • The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
    • Zhang, J. et al. The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature 481, 157-163 (2012).
    • (2012) Nature , vol.481 , pp. 157-163
    • Zhang, J.1
  • 22
    • 84859510141 scopus 로고    scopus 로고
    • EZH2 mutations and their association with PICALM-MLLT10 positive acute leukaemia
    • Grossmann, V. et al. EZH2 mutations and their association with PICALM-MLLT10 positive acute leukaemia. Br. J. Haematol. 157, 387-390 (2012).
    • (2012) Br. J. Haematol. , vol.157 , pp. 387-390
    • Grossmann, V.1
  • 23
    • 84867179824 scopus 로고    scopus 로고
    • The molecular basis of T cell acute lymphoblastic leukemia
    • Van Vlierberghe, P. & Ferrando, A. The molecular basis of T cell acute lymphoblastic leukemia. J. Clin. Invest. 122, 3398-3406 (2012).
    • (2012) J. Clin. Invest. , vol.122 , pp. 3398-3406
    • Van Vlierberghe, P.1    Ferrando, A.2
  • 24
    • 0037033440 scopus 로고    scopus 로고
    • V(D)J-mediated translocations in lymphoid neoplasms: A functional assessment of genomic instability by cryptic sites
    • Marculescu, R., Le, T., Simon, P., Jaeger, U. & Nadel, B. V(D)J-mediated translocations in lymphoid neoplasms: a functional assessment of genomic instability by cryptic sites. J. Exp. Med. 195, 85-98 (2002).
    • (2002) J. Exp. Med. , vol.195 , pp. 85-98
    • Marculescu Le R, T.1    Simon, P.2    Jaeger, U.3    Nadel, B.4
  • 25
    • 84904888382 scopus 로고    scopus 로고
    • PTEN microdeletions in T-cell acute lymphoblastic leukemia are caused by illegitimate RAG-mediated recombination events
    • Mendes, R. D. et al. PTEN microdeletions in T-cell acute lymphoblastic leukemia are caused by illegitimate RAG-mediated recombination events. Blood 124, 567-578 (2014).
    • (2014) Blood , vol.124 , pp. 567-578
    • Mendes, R.D.1
  • 26
    • 0037370378 scopus 로고    scopus 로고
    • Distinct t(7;9)(q34;q32) breakpoints in healthy individuals and individuals with T-ALL
    • Marculescu, R. et al. Distinct t(7;9)(q34;q32) breakpoints in healthy individuals and individuals with T-ALL. Nat. Genet. 33, 342-344 (2003).
    • (2003) Nat. Genet. , vol.33 , pp. 342-344
    • Marculescu, R.1
  • 27
    • 33947231591 scopus 로고    scopus 로고
    • Vivo reinsertion of excised episomes by the V(D)J recombinase: A potential threat to genomic stability
    • Vanura, K. et al. In vivo reinsertion of excised episomes by the V(D)J recombinase: a potential threat to genomic stability. PLoS Biol. 5, e43 (2007).
    • (2007) PLoS Biol. , vol.5 , pp. e43
    • Vanura, K.1
  • 28
    • 33745132455 scopus 로고    scopus 로고
    • Genomic instability due to V(D)J recombination-associated transposition
    • Reddy, Y. V. R., Perkins, E. J. & Ramsden, D. A. Genomic instability due to V(D)J recombination-associated transposition. Genes Dev. 20, 1575-1582 (2006).
    • (2006) Genes Dev. , vol.20 , pp. 1575-1582
    • Reddy, Y.V.R.1    Perkins, E.J.2    Ramsden, D.A.3
  • 29
    • 34948844963 scopus 로고    scopus 로고
    • Chromosomal reinsertion of broken RSS ends during T cell development
    • Curry, J. D. et al. Chromosomal reinsertion of broken RSS ends during T cell development. J. Exp. Med. 204, 2293-2303 (2007).
    • (2007) J. Exp. Med. , vol.204 , pp. 2293-2303
    • Curry, J.D.1
  • 30
    • 0345146909 scopus 로고    scopus 로고
    • Vivo transposition mediated by V(D)J recombinase in human T lymphocytes
    • Messier, T. L., O'Neill, J. P., Hou, S. M., Nicklas, J. A. & Finette, B. A. In vivo transposition mediated by V(D)J recombinase in human T lymphocytes. EMBO J. 22, 1381-1388 (2003).
    • (2003) EMBO J. , vol.22 , pp. 1381-1388
    • Messier, T.L.1    O'Neill, J.P.2    Hou, S.M.3    Nicklas, J.A.4    Finette, B.A.5
  • 31
    • 0037129435 scopus 로고    scopus 로고
    • Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy
    • Hacein-Bey-Abina, S. et al. Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy. New Engl. J. Med. 346, 1185-1193 (2002).
    • (2002) New Engl. J. Med. , vol.346 , pp. 1185-1193
    • Hacein-Bey-Abina, S.1
  • 32
    • 0142084745 scopus 로고    scopus 로고
    • LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
    • Hacein-Bey-Abina, S. et al. LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science 302, 415-419 (2003).
    • (2003) Science , vol.302 , pp. 415-419
    • Hacein-Bey-Abina, S.1
  • 33
    • 84907526739 scopus 로고    scopus 로고
    • Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia
    • Ntziachristos, P. et al. Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia. Nature 514, 513-517 (2014).
    • (2014) Nature , vol.514 , pp. 513-517
    • Ntziachristos, P.1
  • 34
    • 70350500219 scopus 로고    scopus 로고
    • Polycomb group proteins: Navigators of lineage pathways led astray in cancer
    • Bracken, A. P. & Helin, K. Polycomb group proteins: navigators of lineage pathways led astray in cancer. Nat. Rev. Cancer 9, 773-784 (2009).
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 773-784
    • Bracken, A.P.1    Helin, K.2
  • 36
    • 84870485829 scopus 로고    scopus 로고
    • CpG islands and GC content dictate nucleosome depletion in a transcription-independent manner at mammalian promoters
    • Fenouil, R. et al. CpG islands and GC content dictate nucleosome depletion in a transcription-independent manner at mammalian promoters. Genome Res. 22, 2399-2408 (2012).
    • (2012) Genome Res. , vol.22 , pp. 2399-2408
    • Fenouil, R.1
  • 37
    • 33750531056 scopus 로고    scopus 로고
    • Follicular lymphoma-like B cells in healthy individuals: A novel intermediate step in early lymphomagenesis
    • Roulland, S. et al. Follicular lymphoma-like B cells in healthy individuals: a novel intermediate step in early lymphomagenesis. J. Exp. Med. 203, 2425-2431 (2006).
    • (2006) J. Exp. Med. , vol.203 , pp. 2425-2431
    • Roulland, S.1
  • 38
    • 0037769822 scopus 로고    scopus 로고
    • Analysis of TCR, pT alpha, and RAG-1 in T-acute lymphoblastic leukemias improves understanding of early human T-lymphoid lineage commitment
    • Asnafi, V. et al. Analysis of TCR, pT alpha, and RAG-1 in T-acute lymphoblastic leukemias improves understanding of early human T-lymphoid lineage commitment. Blood 101, 2693-2703 (2003).
    • (2003) Blood , vol.101 , pp. 2693-2703
    • Asnafi, V.1
  • 39
    • 10244224017 scopus 로고    scopus 로고
    • Age-related phenotypic and oncogenic differences in T-acute lymphoblastic leukemias may reflect thymic atrophy
    • Asnafi, V. et al. Age-related phenotypic and oncogenic differences in T-acute lymphoblastic leukemias may reflect thymic atrophy. Blood (2004).
    • (2004) Blood
    • Asnafi, V.1
  • 40
    • 34948873711 scopus 로고    scopus 로고
    • Prognostic and oncogenic relevance of TLX1/HOX11 expression level in T-ALLs
    • Bergeron, J. et al. Prognostic and oncogenic relevance of TLX1/HOX11 expression level in T-ALLs. Blood 110, 2324-2330 (2007).
    • (2007) Blood , vol.110 , pp. 2324-2330
    • Bergeron, J.1
  • 41
    • 84873729095 scopus 로고    scopus 로고
    • Multiplex genome engineering using CRISPR/Cas systems
    • Cong, L. et al. Multiplex genome engineering using CRISPR/Cas systems. Science 339, 819-823 (2013).
    • (2013) Science , vol.339 , pp. 819-823
    • Cong, L.1
  • 42
    • 84055218931 scopus 로고    scopus 로고
    • Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells
    • Mochizuki-Kashio, M. et al. Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells. Blood 118, 6553-6561 (2011).
    • (2011) Blood , vol.118 , pp. 6553-6561
    • Mochizuki-Kashio, M.1
  • 43
    • 7344231641 scopus 로고    scopus 로고
    • TAL1 expression does not occur in the majority of T-ALL blasts
    • Delabesse, E. et al. TAL1 expression does not occur in the majority of T-ALL blasts. Br. J. Haematol. 102, 449-457 (1998).
    • (1998) Br. J. Haematol. , vol.102 , pp. 449-457
    • Delabesse, E.1
  • 44
    • 0036242313 scopus 로고    scopus 로고
    • The V(D)J recombinase efficiently cleaves and transposes signal joints
    • Neiditch, M. B., Lee, G. S., Huye, L. E., Brandt, V. L. & Roth, D. B. The V(D)J recombinase efficiently cleaves and transposes signal joints. Mol. Cell 9, 871-878 (2002).
    • (2002) Mol. Cell , vol.9 , pp. 871-878
    • Neiditch, M.B.1    Lee, G.S.2    Huye, L.E.3    Brandt, V.L.4    Roth, D.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.