TAL1 expression does not occur in the majority of T-ALL blasts

British Journal of Haematology

Volumn 102, Issue 2, 1998, Pages 449-457

  Delabesse, Eric ^a,b   Bernard, Muriel ^a   Meyer, Valérie ^b   Smit, Linda ^a,f   Pulford, Karen ^c   Cayuela, Jean Michel ^d   Ritz, Jermoe ^e   Bourquelot, Priscille ^b   Strominger, Jack L ^e   Valensi, Françoise ^b   Macintyre, Elizabeth A ^a,b  

^a CNRS   (France)

^b HÔPITAL NECKER ENFANTS MALADES   (France)

^c Leukaemia Research Fund Immunodiagnostics Unit   (United Kingdom)

^d SAINT LOUIS HOSPITAL   (France)

^e DANA FARBER CANCER INSTITUTE   (United States)

^f NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

GATA1; SIL; T ALL; TAL1

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; TRANSCRIPTION FACTOR;

ACUTE LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ARTICLE; CHILD; GENE EXPRESSION; GENE LOCUS; HUMAN; HUMAN CELL; INFANT; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROGNOSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE;

ADOLESCENT; ADULT; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BLOTTING, SOUTHERN; CHILD; CHILD, PRESCHOOL; DNA-BINDING PROTEINS; ERYTHROID-SPECIFIC DNA-BINDING FACTORS; GATA1 TRANSCRIPTION FACTOR; GENE REARRANGEMENT, T-LYMPHOCYTE; HUMANS; IMMUNOHISTOCHEMISTRY; INFANT; INFANT, NEWBORN; LEUKEMIA, T-CELL, ACUTE; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS; RNA, MESSENGER; TRANSCRIPTION FACTORS;

EID: 7344231641     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1998.00807.x     Document Type: Article

References (40)

1. Aplan, P.D., Lombardi, D.P., Ginsberg, A.M., Cossman, J., Bertness, V.L. & Kirsch, I.R. (1990) Disruption of the human SCL locus by 'illegitimate' V-(D)-J recombinase activity. Science, 250, 1426-1429.
2. Aplan, P.D., Raimondi, S.C. & Kirsch, I.R. (1992) Description of the SCL gene by a a t(1:3) translocation in a patient with T-cell acute lymphoblastic leukemia. Journal of Experimental Medicine, 176, 1303-1310.
3. Baer, R. (1993) TAL1, TAL2 and LYL1 : a family of basic Helix-Loop-Helix proteins implicated in T-cell acute leukaemia. Seminars in Cancer Biology, 4, 341-347.
4. Bash, R.O., Crist, W.M., Shuster, J.J., Link, M.P., Amylon, M., Pullen, J., Carroll, A.J., Buchanan, G.R., Smith, R.G. & Baer, R. (1993) Clinical features and outcome of T-cell acute lymphoblastic leukemia in childhood with respect to alterations at the TAL1 locus, a Pediatric Oncology Group study. Blood, 81, 2110-2117.
5. Bash, R.O., Hall, S., Timmons, C.F., Crist, W.M., Amylon, M., Smith, R.G. & Baer, R. (1995) Does activation of the TAL1 gene occur in a majority of patients with T-cell acute lymphoblastic leukemia? a Pediatric Oncology Group study. Blood, 86, 666-676.
6. Begley, C.G., Aplan, P.A., Davey, M.P., Nakahara, K., Tchorz, K., Kurtzberg, J., Hershfield, M.S., Haynes, B.F., Cohen, D.I., Waldmann, T.A. & Kirsch, I.R. (1989) Chromosomal translocation in a human leukemic stem-cell line disrupts the T-cell antigen receptor δ-chain diversity region and results in a previously unreported fusion transcript. Proceedings of the National Academy of Sciences of the United States of America, 86, 2031-2035.
7. Bernard, O., Azogui, O., Lecointe., N., Mugneret, F., Berger, R., Larsen, C.J. & Mathieu-Mahul, D. (1992) A third TAL1 promoter is specifically used in human T-cell leukemias. Journal of Experimental Medicine, 176, 919-925.
8. Bernard., O., Gugliemi, P., Jonveaux, P., Cherif, D., Gisselbrecht, S., Mauchauffé, M., Berger, R., Larsen, C.-J. & Mathieu-Mahul, D. (1990) Two distinct mechanisms for the SCL gene activation in the t(1:14) translocations of T-cell leukemias. Genes, Chromosomes and Cancer, 1, 194-206.
9. Bernard, O., Lecointe, N., Jonveaux, P., Souyri, M., Mauchauffé, M., Berger, R., Larsen, C.-J. & Mathieu-Mahul, D. (1991) Two site-specific deletions and t(1:14) translocation restricted to human T-cell acute leukemias disrupt the 5′ part of the TAL1 gene. Oncogene, 6, 1477-1488.
10. Breit, T.M., Mol, E.J., Wolvers-Tettero, I.L.M., Ludwig, W.D., Vanwering, E.R. & Van Dongen, J.J.M. (1993) Site-specific deletions involving the TAL1 and SIL genes are restricted to cells of the T-cell receptor alpha/beta lineage: T-cell receptor-delta gene deletion mechanism affects multiple genes. Journal of Experimental Medicine, 177, 965-977.
11. Brown, L., Cheng, J.-T., Chen, Q., Siciliano, M., Crist, W., Buchanan, G. & Baer, R. (1990) Site specific recombination of the TAL1 gene is a common occurrence in human T cell leukemia. EMBO Journal, 9, 3343-3351.
12. Chen, Q., Cheng, J.-Y., Tsai, L-H., Schneider, N., Buchanan, G., Carroll, A., Crist, W., Ozanne, B., Siciliano, M. & Baer, R. (1990) The TAL1 gene undergoes chromosome translocation in a T-cell leukemia and potentially encodes a helix-loop-helix protein. EMBO Journal, 9, 415-424.
13. Cheng, J.T., Hsu, H.L., Hwang, L.Y. & Baer, R. (1993) Products of the TAL1 oncogene: basic helix-loop-helix proteins phosphorylated at serine residues. Oncogene, 8, 677-683.
14. Chetty, R., Pulford, K., Jones, M., Matheiu-Mahul, D., Close, P., Hussein, S., Pallesen, G., Ralfkiaer, E., Stein, H., Gatter, K. & Mason, D. (1995) SCL/TAL1 expression in T-acute lymphoblastic leukemia: an immunohistochemical and genotypic study. Human Pathology, 26, 994-998.
15. Chetty, R., Pulford, K., Jones, M., Matheiu-Mahul, D., Close, P., Hussein, S., Pallesen., G., Ralfkiaer, E., Stein, H., Gatter, K. & Mason, D. (1996) An immunohistochemical study of TAL1 protein expression in leukaemias and lymphomas with a novel monoclonal antibody, 2TL242. Journal of Pathology, 178, 311-315.
16. Condorelli, G., Vitelli, L., Valtieri, M., Marta, I., Montesoro, E., Lulli, V., Baer, R. & Peschle, C. (1995) Coordinate expression and developmental role of Id2 protein and TAL1/E2A heterodimer in erythroid progenitor differentiation. Blood, 86, 164-175.
17. d variants. British Journal of Haematology, 99, 901-907.
18. Elwood, N.J., Cook, W.D., Metcalf, D. & Begley, C.G. (1993) SCL, the gene implicated in human T-cell leukaemia, is oncogenic in a murine T-lymphocyte cell line. Oncogene, 8, 3093-3101.
19. Erber, W.N., Mynheer. L.C. & Mason, D.Y. (1986) APAAP labelling of blood and bone-marrow samples for phenotyping leukaemia. Lancet, i, 761-765.
20. Fischer, E.H., Charbonneau, H. & Tonks, N.K. (1991) Protein tyrosine phosphatases: a diverse family of intracellular and transmembrane enzymes. Science, 253, 401-406.
21. Fitzgerald, T.J., Neale, G.A.M., Raimondi, S.C. & Goorha, R.M. (1991) c-TAL, a helix-loop-helix is juxtaposed to the T-cell receptor β chain gene by a reciprocal translocation t(1:7) (p32;q35). Blood, 78, 2686-2691.
22. Goldfarb, A.N., Goueli, S., Mickelson, D. & Greenberg, J.M. (1992) T-cell acute lymphoblastic leukemia: the associated gene SCL/TAL codes for a 42 Kd nuclear phophoprotein. Blood, 80, 2858-2866.
23. Huang, W., Kuang, S.Q., Huang, Q.H., Dong, S., Zhang, T., Gu, L.J., Ching, L.M., Chen, S.J., Chang, L.C. & Chen, Z. (1995) RT/PCR detection of SIL-TAL1 fusion mRNA in Chinese T-cell acute lymphoblastic leukemia (T-ALL), Cancer Genetics and Cytogenetics, 81, 76-82.
24. Izraeli, S., Colaizzo-Anas, T., Bertness, V.L., Mani, K., Aplan, P.D. & Kirsch, I.R. (1997) Expression of the SIL gene is correlated with growth induction and cellular proliferation. Cell Growth and Differentiation, 8, 1171-1179.
25. Kallianpur, A.R., Jordan, J.E. & Brandt, S.J. (1994) The SCL/TAL1 gene is expressed in progenitors of both the hematopoietic and vascular systems during embryogenesis. Blood, 83, 1200-1208.
26. Larson, R.C., Lavenir, I., Larson, T.A., Baer, R., Warren, A.J., Wadman, I., Nottage, K. & Rabbitts, T.H. (1996) Protein dimerization between LMO2 (Rbtn2) and TAL1 alters thymocyte development and potentiates T-cell tumorigenesis in transgenic mice. EMBO Journal, 15, 1021-1027.
27. Leroy-Viard, K., Vinit, M.A., Lecointe, N., Jouault, H., Hibner, U., Romeo, P.H. & Matheiu-Mahul, D. (1995) Loss of TAL1 protein activity induces premature apoptosis of Jurkat leukemic T-cells upon medium depletion. EMBO Journal, 14, 2341-2349.
28. MacIntyre, E.A., Smit, L., Ritz, J., Kirsch, I.R. & Strominger, J.L. (1992) Disruption of the SCL locus in T-lymphoid malignancies correlates with commitment to the T-cell receptor αβ lineage. Blood, 80, 1511-1520.
29. Mouthon, M.A., Bernard, O., Mitjavila, M.T., Romeo, P.H., Vainchenker, W. & Mathieu-Mahul, D. (1993) Expression of TAL1 and GATA-binding proteins during human hematopoiesis. Blood, 81, 647-655.
30. Murrell, A.M., Bockamp, E.O., Gottgens, B., Chan, Y.S., Cross, M.A., Heyworth, C.M. & Green, A.R. (1995) Discordant regulation of SCL/TAL1 mRNA and protein during erythroid differentiation. Oncogene, 11, 131-139.
31. Neale, G.A., Rehg, J.E. & Goorha, R.M. (1997) Disruption of T-cell differentiation precedes T-cell tumor formation in LMO2 (rhombotin-2) transgenic mice. Leukemia, 11, (Suppl. 3), 289-290.
32. Newman, P.J., Berndt, M.C., Gorski, J., White, G.C., Lyman, S., Paddock, C. & Muller, W.A. (1990) PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. Science, 247, 1219-1222.
33. Orkin, S.H. (1992) GATA-binding transcription factors in hernatopoietic cells. Blood, 80, 575-581.
34. Poirel, H., Rack, K., Delabesse, E., Radford-Weiss, I., Troussard, X., Deberl, C., Leboeuf, D., Bastard, C., Picard, F., Veil-Buzyn, A., Flandrin, G., Bernard, O. & Macintyre, E. (1996) Incidence and characterization of MLL gene (11q23) rearrangements in acute myeloid leukemia M1 and M5. Blood, 87, 2496-2505.
35. Poirel, H., Radford-Weiss, I., Rack, K., Troussard, X., Veil, A., Valensi, F., Picard, F., Guesnu, M., Leboeuf, D., Melle, J., Dreyfus, F., Flandrin, G.& Macintryre, E. (1995) Detection of the chromosome 16 CBFβ-MYH11 fusion transcript in myelomonocytic leukemias. Blood, 85, 1313-1322.
36. Pulford, K., Lecointe, N., Leroy-Viard, K., Jones, M., Matheiu-Mahul, D. & Mason, D.Y. (1995) Expression of TAL1 proteins in human tissues. Blood, 85, 675-684.
37. Smit, L., Ritz, J., Strominger, J.L. & Macintyre, E.A. (1992) Expression of the SCL/TAL1 gene is common in T-ALL in the absence of any detectable disruption of the gene. Blood, 80, 303a.
38. Stockinger, H., Gadd, S.J., Eher, R., Majdic, O., Schreiber, W., Kasinrerk, W., Strass, B., Schnabl, E. & Knapp, W. (1990) Molecular characterization and functional analysis of the leukocyte surface protein CD31. Journal of Immunology, 145, 3889-3897.
39. Trainor, C.D., Evans, T., Felsenfeld, G. & Boguski, M.S. (1990) Structure and evolution of a human erythroid transcription factor. Nature, 343, 92-96.
40. Visvader, J. & Begley, C.G. (1991) Helix-loop-helix genes translocated in lymphoid leukemia. Trends in Biochemical Sciences, 16, 330-334.