EZH2 mutations and their association with PICALM-MLLT10 positive acute leukaemia

British Journal of Haematology

Volumn 157, Issue 3, 2012, Pages 387-390

  Grossmann, Vera ^a   Bacher, Ulrike ^b   Kohlmann, Alexander ^a   Artusi, Valentina ^a   Klein, Hans Ulrich ^c   Dugas, Martin ^c   Schnittger, Susanne ^a   Alpermann, Tamara ^a   Kern, Wolfgang ^a   Haferlach, Torsten ^a   Haferlach, Claudia ^a  

^a MLL MUNICH LEUKEMIA LABORATORY   (Germany)

^b UNIVERSITY OF HAMBURG   (Germany)

^c UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Deep sequencing; DNMT3A mutations; EZH2 mutations; T(10; 11)(p13; q14) PICALM MLLT10 rearrangement; T cell acute lymphoblastic leukaemia lymphoma (T ALL)

Indexed keywords

ALANINE; ARGININE; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; GLYCINE; HISTIDINE; LEUCINE; MIXED LINEAGE LEUKEMIA PROTEIN; NOTCH1 RECEPTOR; ONCOPROTEIN; PHENYLALANINE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PICALM PROTEIN; PROTEIN KINASE B; THREONINE; TRANSCRIPTION FACTOR EZH2; TYROSINE; UNCLASSIFIED DRUG; VALINE;

ACUTE GRANULOCYTIC LEUKEMIA; ADOLESCENT; ADULT; AGED; AMINO ACID SUBSTITUTION; CELL STRUCTURE; CHILD; CHROMOSOME BANDING PATTERN; CLINICAL ARTICLE; CONTROLLED STUDY; EZH2 GENE; FEMALE; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION PROFILING; GENE MUTATION; GENE REARRANGEMENT; GENETIC ASSOCIATION; HOX GENE; HUMAN; IMMUNOPHENOTYPING; LETTER; MALE; MISSENSE MUTATION; MUTATIONAL ANALYSIS; ONCOGENE; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCHOOL CHILD; SEQUENCE ANALYSIS; T CELL LEUKEMIA;

ACUTE DISEASE; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CHILD; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION PROFILING; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LEUKEMIA; MALE; MIDDLE AGED; MUTATION; NEOPLASM PROTEINS; ONCOGENE PROTEINS, FUSION; TRANSCRIPTION FACTORS; YOUNG ADULT;

EID: 84859510141     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2011.08986.x     Document Type: Letter

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