In vivo reinsertion of excised episomes by the V(D)J recombinase: A potential threat to genomic stability

PLoS Biology

Volumn 5, Issue 3, 2007, Pages 0515-0530

  Vanura, Katrina ^a   Montpellier, Bertrand ^b,c,d   Le, Trang ^a   Spicuglia, Salvatore ^b,c,d   Navarro, Jean Marc ^b,c,d   Cabaud, Olivier ^b,c,d   Roulland, Sandrine ^b,c,d   Vachez, Elodie ^b,c,d,e   Prinz, Immo ^b,c,d   Ferrier, Pierre ^b,c,d   Marculescu, Rodrig ^a,f   Jäger, Ulrich ^a   Nadel, Bertrand ^b,c,d  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

^c INSERM   (France)

^d CNRS   (France)

^e Parc Scientifique de Luminy   (France)

^f KRANKENANSTALT RUDOLFSTIFTUNG   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINASE;

ANIMAL CELL; ARTICLE; CHROMOSOME ABERRATION; CHROMOSOME BREAKAGE; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; EPISOME; EX VIVO STUDY; GENE INSERTION; GENE REARRANGEMENT; GENE TRANSLOCATION; GENETIC RECOMBINATION; GENOME; GENOMIC INSTABILITY; IN VIVO STUDY; LYMPHATIC LEUKEMIA; MOUSE; NONHUMAN; RECEPTOR GENE; T LYMPHOCYTE; ANIMAL; CELL CULTURE; GENETICS; METABOLISM; POLYMERASE CHAIN REACTION; T CELL LEUKEMIA;

ANIMALS; CELLS, CULTURED; GENOMIC INSTABILITY; LEUKEMIA, T-CELL, ACUTE; MICE; POLYMERASE CHAIN REACTION; RECOMBINATION, GENETIC; TRANSLOCATION, GENETIC; VDJ RECOMBINASES;

EID: 33947231591     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.0050043     Document Type: Article

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