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Volumn 25, Issue 6, 2014, Pages 805-819

Oxidative stress and genetic markers of suboptimal antioxidant defense in the aging brain: A theoretical review

Author keywords

Antioxidant defense enzymes; Brain aging; Genetic risk; Oxidative stress

Indexed keywords

ANTIOXIDANT; CATALASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; MYELIN; SUPEROXIDE DISMUTASE; GENETIC MARKER;

EID: 84922902834     PISSN: 03341763     EISSN: 21910200     Source Type: Journal    
DOI: 10.1515/revneuro-2014-0046     Document Type: Article
Times cited : (97)

References (179)
  • 1
    • 33646375416 scopus 로고    scopus 로고
    • T null and M null genotypes of the glutathione S-transferase gene are risk factor for CAD independent of smoking
    • Abu-Amero, K.K., Al-Boudari, O.M., Mohamed, G.H., and Dzimiri, N. (2006). T null and M null genotypes of the glutathione S-transferase gene are risk factor for CAD independent of smoking. BMC. Med. Gen. 1, 38.
    • (2006) BMC. Med. Gen. , vol.1 , pp. 38
    • Abu-Amero, K.K.1    Al-Boudari, O.M.2    Mohamed, G.H.3    Dzimiri, N.4
  • 2
    • 77249110320 scopus 로고    scopus 로고
    • Absolute diffusivities define the landscape of white matter degeneration in Alzheimer's disease
    • Acosta-Cabronero, J., Williams, G.B., Pengas, G., and Nestor, P.J. (2010). Absolute diffusivities define the landscape of white matter degeneration in Alzheimer's disease. Brain 133, 529-539.
    • (2010) Brain , vol.133 , pp. 529-539
    • Acosta-Cabronero, J.1    Williams, G.B.2    Pengas, G.3    Nestor, P.J.4
  • 3
    • 0033624419 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative stress in aging and neurodegenerative disease
    • Albers, D.S. and Beal, M.F. (2000). Mitochondrial dysfunction and oxidative stress in aging and neurodegenerative disease. Adv. Dement. Res. 59, 133-154.
    • (2000) Adv. Dement. Res. , vol.59 , pp. 133-154
    • Albers, D.S.1    Beal, M.F.2
  • 4
    • 0032469832 scopus 로고    scopus 로고
    • Oxidative stress and superoxide dismutase in development, aging and gene regulation
    • Allen, R.G. (1998). Oxidative stress and superoxide dismutase in development, aging and gene regulation. Age 21, 47-76.
    • (1998) Age , vol.21 , pp. 47-76
    • Allen, R.G.1
  • 5
  • 6
    • 75949121583 scopus 로고    scopus 로고
    • Oxidative stress in the progression of Alzheimer disease in the frontal cortex
    • Ansari, M.A. and Scheff, S.W. (2010). Oxidative stress in the progression of Alzheimer disease in the frontal cortex. J. Neuropathol. Exp. Neurol. 69, 155.
    • (2010) J. Neuropathol. Exp. Neurol. , vol.69 , pp. 155
    • Ansari, M.A.1    Scheff, S.W.2
  • 7
    • 56649105351 scopus 로고    scopus 로고
    • Regulation of neuronal glutathione synthesis
    • Aoyama, K., Watabe, M., and Nakaki, T. (2008). Regulation of neuronal glutathione synthesis. J. Pharmacol. Sci. 108, 227-238.
    • (2008) J. Pharmacol. Sci. , vol.108 , pp. 227-238
    • Aoyama, K.1    Watabe, M.2    Nakaki, T.3
  • 8
    • 33846634703 scopus 로고    scopus 로고
    • Exploratory voxel-based analysis of diffusion indices and hemispheric asymmetry in normal aging
    • Ardekani, S., Kumar, A., Bartzokis, G., and Sinha, U. (2007). Exploratory voxel-based analysis of diffusion indices and hemispheric asymmetry in normal aging. Magn. Reson. Imaging 25, 154-167.
    • (2007) Magn. Reson. Imaging , vol.25 , pp. 154-167
    • Ardekani, S.1    Kumar, A.2    Bartzokis, G.3    Sinha, U.4
  • 9
    • 84861309322 scopus 로고    scopus 로고
    • Therapeutic potential of targeting hydrogen peroxide metabolism in the treatment of brain ischaemia
    • Armogida, M., Nisticò, R., and Mercuri, N.B. (2012). Therapeutic potential of targeting hydrogen peroxide metabolism in the treatment of brain ischaemia. Br. J. Pharmacol. 166, 1211-1224.
    • (2012) Br. J. Pharmacol. , vol.166 , pp. 1211-1224
    • Armogida, M.1    Nisticò, R.2    Mercuri, N.B.3
  • 10
  • 11
    • 40749101520 scopus 로고    scopus 로고
    • Diffusion tensor imaging (DTI)- based white matter mapping in brain research: A review
    • Assaf, Y. and Pasternak, O. (2008). Diffusion tensor imaging (DTI)- based white matter mapping in brain research: A review. J. Mol. Neurosci. 34, 51-61.
    • (2008) J. Mol. Neurosci. , vol.34 , pp. 51-61
    • Assaf, Y.1    Pasternak, O.2
  • 12
    • 0030830935 scopus 로고    scopus 로고
    • Peroxide modulation of slow onset potentiation in rat hippocampus
    • Auerbach, J.M. and Segal, M. (1997). Peroxide modulation of slow onset potentiation in rat hippocampus. J. Neurosci. 17, 8695-8701.
    • (1997) J. Neurosci. , vol.17 , pp. 8695-8701
    • Auerbach, J.M.1    Segal, M.2
  • 14
    • 84889089505 scopus 로고    scopus 로고
    • Frequency of polymorphism-262 C/T in catalase gene and oxidative damage in Slovak children with bronchial asthma
    • Babusikova, E., Jesenak, M., Evinova, A., Banovcin, P., and Dobrota, D. (2013b). Frequency of polymorphism-262 C/T in catalase gene and oxidative damage in Slovak children with bronchial asthma. Arch. Bronconeumol. 49, 507-512.
    • (2013) Arch. Bronconeumol. , vol.49 , pp. 507-512
    • Babusikova, E.1    Jesenak, M.2    Evinova, A.3    Banovcin, P.4    Dobrota, D.5
  • 15
    • 0029102337 scopus 로고
    • An investigation of antioxidant status, DNA repair capacity and mutation as a function of age in humans
    • Barnett, Y.A. and King, C.M. (1995). An investigation of antioxidant status, DNA repair capacity and mutation as a function of age in humans. Mutation Res./DNAging 338, 115-128.
    • (1995) Mutation Res./DNAging , vol.338 , pp. 115-128
    • Barnett, Y.A.1    King, C.M.2
  • 16
    • 0346770038 scopus 로고    scopus 로고
    • Age-related myelin breakdown: A developmental model of cognitive decline and Alzheimer's disease
    • Bartzokis, G. (2004). Age-related myelin breakdown: A developmental model of cognitive decline and Alzheimer's disease. Neurobiol. Aging 25, 5-18.
    • (2004) Neurobiol. Aging , vol.25 , pp. 5-18
    • Bartzokis, G.1
  • 17
    • 84859413065 scopus 로고    scopus 로고
    • Microstructural and physiological features of tissues elucidated by quantitative-diffusiontensor MRI
    • Basser, P.J. and Pierpaoli, C. (2011). Microstructural and physiological features of tissues elucidated by quantitative-diffusiontensor MRI. J. Magn. Reson. 213, 560-570.
    • (2011) J. Magn. Reson. , vol.213 , pp. 560-570
    • Basser, P.J.1    Pierpaoli, C.2
  • 18
    • 84906790803 scopus 로고    scopus 로고
    • Disconnected aging: Cerebral white matter integrity and age-related differences in cognition
    • [Epub ahead of print]
    • Bennett, I.J. and Madden, D.J. (2013). Disconnected aging: Cerebral white matter integrity and age-related differences in cognition. Neuroscience. doi: 10.1016/j.neuroscience.2013.11.026. [Epub ahead of print].
    • (2013) Neuroscience
    • Bennett, I.J.1    Madden, D.J.2
  • 19
    • 77956353189 scopus 로고    scopus 로고
    • Association of glutathione S-transferase (GSTM1, T1 and P1) gene polymorphisms with type 2 diabetes mellitus in north Indian population
    • Bid, H.K., Konwar, R., Saxena, M., Chaudhari, P., Agrawal, C.G., and Banerjee, M. (2010). Association of glutathione S-transferase (GSTM1, T1 and P1) gene polymorphisms with type 2 diabetes mellitus in north Indian population. J. Postgrad. Med. 56, 176-81.
    • (2010) J. Postgrad. Med. , vol.56 , pp. 176-81
    • Bid, H.K.1    Konwar, R.2    Saxena, M.3    Chaudhari, P.4    Agrawal, C.G.5    Banerjee, M.6
  • 20
    • 0037373449 scopus 로고    scopus 로고
    • Mitochondria from females exhibit higher antioxidant gene expression and lower oxidative damage than males
    • Borrás, C., Sastre, J., García-Sala, D., Lloret, A., Pallardó, F.V., and Viña, J. (2003). Mitochondria from females exhibit higher antioxidant gene expression and lower oxidative damage than males. Free Radical Biol. Aging 34, 546-552.
    • (2003) Free Radical Biol. Aging , vol.34 , pp. 546-552
    • Borrás, C.1    Sastre, J.2    García-Sala, D.3    Lloret, A.4    Pallardó, F.V.5    Viña, J.6
  • 22
    • 78651084322 scopus 로고    scopus 로고
    • Review: Cerebral microvascular pathology in ageing and neurodegeneration
    • Brown, W.R. and Thore, C.R. (2011). Review: Cerebral microvascular pathology in ageing and neurodegeneration. Neuropathol. Appl. Neurobiol. 37, 56-74.
    • (2011) Neuropathol. Appl. Neurobiol. , vol.37 , pp. 56-74
    • Brown, W.R.1    Thore, C.R.2
  • 24
    • 33747036919 scopus 로고    scopus 로고
    • Oxidative stress in Alzheimer's disease brain: New insights from redox proteomics
    • Butterfield, D. A., Perluigi, M., & Sultana, R. (2006). Oxidative stress in Alzheimer's disease brain: New insights from redox proteomics. European journal of pharmacology, 545, 39-50.
    • (2006) European journal of pharmacology , vol.545 , pp. 39-50
    • Butterfield, D.A.1    Perluigi, M.2    Sultana, R.3
  • 25
    • 0031021275 scopus 로고    scopus 로고
    • A model for the coupling between cerebral blood flow and oxygen metabolism during neural stimulation
    • Buxton, R.B. and Frank, L.R. (1997). A model for the coupling between cerebral blood flow and oxygen metabolism during neural stimulation. J. Cereb. Blood Flow Metab. 17, 64-72.
    • (1997) J. Cereb. Blood Flow Metab. , vol.17 , pp. 64-72
    • Buxton, R.B.1    Frank, L.R.2
  • 27
    • 1842525777 scopus 로고    scopus 로고
    • Increased expression of heat shock proteins in rat brain during aging: Relationship with mitochondrial function and glutathione redox state
    • Calabrese, V., Scapagnini, G., Ravagna, A., Colombrita, C., Spadaro, F., Butterfield, D.A., and Giuffrida Stella, A.M. (2004). Increased expression of heat shock proteins in rat brain during aging: Relationship with mitochondrial function and glutathione redox state. Mech. Ageing Dev. 125, 325-335.
    • (2004) Mech. Ageing Dev. , vol.125 , pp. 325-335
    • Calabrese, V.1    Scapagnini, G.2    Ravagna, A.3    Colombrita, C.4    Spadaro, F.5    Butterfield, D.A.6    Giuffrida Stella, A.M.7
  • 28
    • 0034019969 scopus 로고    scopus 로고
    • Vascular endothelium is a site of free radical production and inflammation in areas of neuronal loss in thiamine-deficient brain
    • Calingasan, N.Y. and Gibson, G.E. (2000). Vascular endothelium is a site of free radical production and inflammation in areas of neuronal loss in thiamine-deficient brain. Ann. N.Y. Acad. Sci. 903, 353-356.
    • (2000) Ann. N.Y. Acad. Sci. , vol.903 , pp. 353-356
    • Calingasan, N.Y.1    Gibson, G.E.2
  • 30
    • 57049120497 scopus 로고    scopus 로고
    • GSTM1-null polymorphism as possible risk marker for hypertension: Results from the aging and longevity study in the Sirente Geographic Area (ilSIRENTE study
    • Capoluongo, E., Onder, G., Concolino, P., Russo, A., Santonocito, C., Bernabei, R., Zuppi, C., Ameglio, F., and Landi, F. (2009). GSTM1-null polymorphism as possible risk marker for hypertension: Results from the aging and longevity study in the Sirente Geographic Area (ilSIRENTE study). Clin. Chim. Acta 399, 92-96.
    • (2009) Clin. Chim. Acta , vol.399 , pp. 92-96
    • Capoluongo, E.1    Onder, G.2    Concolino, P.3    Russo, A.4    Santonocito, C.5    Bernabei, R.6    Zuppi, C.7    Ameglio, F.8    Landi, F.9
  • 31
    • 41349107780 scopus 로고    scopus 로고
    • Glutathione S-transferase M1 (GSTM1) polymorphisms and lung cancer: A literature-based systematic HuGE review and meta-analysis
    • Carlsten, C., Sagoo, G.S., Frodsham, A.J., Burke, W., and Higgins, J.P.T. (2008). Glutathione S-transferase M1 (GSTM1) polymorphisms and lung cancer: A literature-based systematic HuGE review and meta-analysis. Am. J. Epidemiol. 167, 759-774.
    • (2008) Am. J. Epidemiol. , vol.167 , pp. 759-774
    • Carlsten, C.1    Sagoo, G.S.2    Frodsham, A.J.3    Burke, W.4    Higgins, J.P.T.5
  • 32
    • 33646083956 scopus 로고    scopus 로고
    • The 262T?C promoter polymorphism of the catalase gene is associated with diabetic neuropathy in type 1 diabetic Russian patients
    • Chistiakov, D.A., Zotova, E.V., Savost'anov, K.V., Bursa, T.R., Galeev, I.V., Strokov, A., and Nosikov, V.V. (2006). The 262T?C promoter polymorphism of the catalase gene is associated with diabetic neuropathy in type 1 diabetic Russian patients. Diabetes Metab. 32, 63-68.
    • (2006) Diabetes Metab. , vol.32 , pp. 63-68
    • Chistiakov, D.A.1    Zotova, E.V.2    Savost'anov, K.V.3    Bursa, T.R.4    Galeev, I.V.5    Strokov, A.6    Nosikov, V.V.7
  • 34
    • 0030174825 scopus 로고    scopus 로고
    • Relationship of iron to oligondendrocytes and myelination
    • Connor, J.R. and Menzies, S.L. (1996). Relationship of iron to oligondendrocytes and myelination. Glia 17, 83-93.
    • (1996) Glia , vol.17 , pp. 83-93
    • Connor, J.R.1    Menzies, S.L.2
  • 35
    • 0034801462 scopus 로고    scopus 로고
    • Increased infarct size and exacerbated apoptosis in the glutathione peroxidase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injury
    • Crack, P.J., Taylor, J.M., Flentjar, N.J., De Haan, J., Hertzog, P., Iannello, R.C., and Kola, I. (2001). Increased infarct size and exacerbated apoptosis in the glutathione peroxidase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injury. J. Neurochem. 78, 1389-1399.
    • (2001) J. Neurochem. , vol.78 , pp. 1389-1399
    • Crack, P.J.1    Taylor, J.M.2    Flentjar, N.J.3    De Haan, J.4    Hertzog, P.5    Iannello, R.C.6    Kola, I.7
  • 37
    • 80054679916 scopus 로고    scopus 로고
    • Oxidative stress in vascular aging
    • (Springer Science+Business Media, LLC: Humana Press). Print
    • Csiszar, A. and Ungvari, Z. (2010). Oxidative stress in vascular aging. In Studies on Cardiovascular Disorders. (Springer Science+Business Media, LLC: Humana Press). pp. 245-261. Print ISBN: 978-1-60761-599-6, Online ISBN: 978-1-60761-600- 9. DOI: 10.1007/978-1-60761-600-9-13.
    • (2010) Studies on Cardiovascular Disorders , pp. 245-261
    • Csiszar, A.1    Ungvari, Z.2
  • 38
    • 55849118128 scopus 로고    scopus 로고
    • Apolipoprotein E and cholesterol in aging and disease in the brain
    • de Chaves, E.P. and Narayanaswami, V. (2008). Apolipoprotein E and cholesterol in aging and disease in the brain. Future Lipidol. 3, 505-530.
    • (2008) Future Lipidol. , vol.3 , pp. 505-530
    • De Chaves, E.P.1    Narayanaswami, V.2
  • 39
    • 0242268555 scopus 로고    scopus 로고
    • Alterations in the BOLD fMRI signal with ageing and disease: A challenge for neuroimaging
    • D'esposito, M., Deouell, L.Y., and Gazzaley, A. (2003). Alterations in the BOLD fMRI signal with ageing and disease: A challenge for neuroimaging. Nat. Rev. Neurosci. 4 863-872.
    • (2003) Nat. Rev. Neurosci. , vol.4 , pp. 863-872
    • D'esposito, M.1    Deouell, L.Y.2    Gazzaley, A.3
  • 40
    • 11144227402 scopus 로고    scopus 로고
    • Anatomical mapping of white matter hyperintensities (wmh) exploring the relationships between periventricular WMH, deep WMH, and total WMH burden
    • DeCarli, C., Fletcher, E., Ramey, V., Harvey, D., & Jagust, W. J. (2005). Anatomical mapping of white matter hyperintensities (wmh) exploring the relationships between periventricular WMH, deep WMH, and total WMH burden. Stroke, 36, 50-55.
    • (2005) Stroke , vol.36 , pp. 50-55
    • DeCarli, C.1    Fletcher, E.2    Ramey, V.3    Harvey, D.4    Jagust, W.J.5
  • 41
    • 0034672943 scopus 로고    scopus 로고
    • Metabolism and functions of glutathione in brain
    • Dringen, R. (2000). Metabolism and functions of glutathione in brain. Prog. Neurobiol. 62, 649-671.
    • (2000) Prog. Neurobiol. , vol.62 , pp. 649-671
    • Dringen, R.1
  • 42
    • 33745247801 scopus 로고    scopus 로고
    • Oxidative stress and ageing: Is ageing a cysteine deficiency syndrome?
    • Dröge, W. (2005). Oxidative stress and ageing: Is ageing a cysteine deficiency syndrome?. Philos. Trans. R. Soc. Lond. B Biol. Sci. 360, 2355-2372.
    • (2005) Philos. Trans. R. Soc. Lond. B Biol. Sci. , vol.360 , pp. 2355-2372
    • Dröge, W.1
  • 44
    • 84905367645 scopus 로고    scopus 로고
    • Mechanical properties of normal and diseased cerebrovascular system
    • Ebrahimi, A.P. (2009). Mechanical properties of normal and diseased cerebrovascular system. J. Vasc. Intervent. Dement. 2, 155.
    • (2009) J. Vasc. Intervent. Dement. , vol.2 , pp. 155
    • Ebrahimi, A.P.1
  • 45
    • 60549086571 scopus 로고    scopus 로고
    • Aging: An important factor for the pathogenesis of neurodegenerative diseases
    • Farooqui, T. and Farooqui, A.A. (2009). Aging: An important factor for the pathogenesis of neurodegenerative diseases. Mech. Aging Dev. 130, 203-215.
    • (2009) Mech. Aging Dev. , vol.130 , pp. 203-215
    • Farooqui, T.1    Farooqui, A.A.2
  • 47
    • 0031980129 scopus 로고    scopus 로고
    • Chronic dietary n-3 polyunsaturated fatty acids deficiency affects the fatty acid composition of plasmenylethanolamine and phosphatidylethanolamine differently in rat frontal cortex, striatum, and cerebellum
    • Favreliere, S., Barrier, L., Durand, G., Chalon, S., and Tallineau, C. (1998). Chronic dietary n-3 polyunsaturated fatty acids deficiency affects the fatty acid composition of plasmenylethanolamine and phosphatidylethanolamine differently in rat frontal cortex, striatum, and cerebellum. Lipids 33, 401-407.
    • (1998) Lipids , vol.33 , pp. 401-407
    • Favreliere, S.1    Barrier, L.2    Durand, G.3    Chalon, S.4    Tallineau, C.5
  • 48
    • 0016823810 scopus 로고
    • Mini-mental state" a practical method for grading the cognitive state of patients for the clinician
    • Folstein, M.F., Folstein, S.E., and McHugh, P.R. (1975). "Mini-mental state" a practical method for grading the cognitive state of patients for the clinician. J. Psychiatr. Res. 12, 189-198.
    • (1975) J. Psychiatr. Res. , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 49
    • 0035282473 scopus 로고    scopus 로고
    • A common functional CT substitution polymorphism in the promoter region of the human catalase gene influences transcription factor binding, reporter gene transcription and is correlated to blood catalase levels
    • Forsberg, L., Lyrenäs, L., Morgenstern, R., and de Faire, U. (2001). A common functional CT substitution polymorphism in the promoter region of the human catalase gene influences transcription factor binding, reporter gene transcription and is correlated to blood catalase levels. Free Radical Biol. Med. 30, 500-505.
    • (2001) Free Radical Biol. Med. , vol.30 , pp. 500-505
    • Forsberg, L.1    Lyrenäs, L.2    Morgenstern, R.3    De Faire, U.4
  • 50
    • 34249051111 scopus 로고    scopus 로고
    • Calcium homeostasis and modulation of synaptic plasticity in the aged brain
    • Foster, T.C. (2007). Calcium homeostasis and modulation of synaptic plasticity in the aged brain. Aging Cell. 6, 319-325.
    • (2007) Aging Cell. , vol.6 , pp. 319-325
    • Foster, T.C.1
  • 51
    • 0033231361 scopus 로고    scopus 로고
    • Regulation of antioxidant enzyme gene expression in response to oxidative stress and during differentiation of mouse skeletal muscle
    • Franco, A.A., Odom, R.S., and Rando, T.A. (1999). Regulation of antioxidant enzyme gene expression in response to oxidative stress and during differentiation of mouse skeletal muscle. Free Radical Biol. Med. 27, 1122-1132.
    • (1999) Free Radical Biol. Med. , vol.27 , pp. 1122-1132
    • Franco, A.A.1    Odom, R.S.2    Rando, T.A.3
  • 52
    • 62549085618 scopus 로고    scopus 로고
    • Human genetic variation and its contribution to complex traits
    • Frazer, K.A., Murray, S.S., Schork, N.J., and Topol, E.J. (2009). Human genetic variation and its contribution to complex traits. Nat. Rev. Genet. 10, 241-251.
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 241-251
    • Frazer, K.A.1    Murray, S.S.2    Schork, N.J.3    Topol, E.J.4
  • 53
    • 25844474404 scopus 로고    scopus 로고
    • Interactions of interleukin-1 with neurotrophic factors in the central nervous system
    • Friedman, W.J. (2005). Interactions of interleukin-1 with neurotrophic factors in the central nervous system. Mol. Neurobiol. 32, 133-144.
    • (2005) Mol. Neurobiol. , vol.32 , pp. 133-144
    • Friedman, W.J.1
  • 54
    • 15544377792 scopus 로고    scopus 로고
    • Neuroprotective effect of an antioxidant in ischemic brain injury
    • Fujimura, M., Tominaga, T., and Chan, P.H. (2005). Neuroprotective effect of an antioxidant in ischemic brain injury. Neurocrit. Care 2, 59-66.
    • (2005) Neurocrit. Care , vol.2 , pp. 59-66
    • Fujimura, M.1    Tominaga, T.2    Chan, P.H.3
  • 55
    • 0036069786 scopus 로고    scopus 로고
    • Extracellular superoxide dismutase and cardiovascular disease
    • Fukai, T., Folz, R.J., Landmesser, U., and Harrison, D.G. (2002). Extracellular superoxide dismutase and cardiovascular disease. Cardiovasc. Res. 55, 239-249.
    • (2002) Cardiovasc. Res. , vol.55 , pp. 239-249
    • Fukai, T.1    Folz, R.J.2    Landmesser, U.3    Harrison, D.G.4
  • 57
    • 0036734230 scopus 로고    scopus 로고
    • Age-related total gray matter and white matter changes in normal adult brain. Part I: Volumetric MR imaging analysis
    • Ge, Y., Grossman, R.I., Babb, J.S., Rabin, M.L., Mannon, L.J., and Kolson, D.L. (2002). Age-related total gray matter and white matter changes in normal adult brain. Part I: Volumetric MR imaging analysis. Am. J. Neuroradiol. 23, 1327-1333.
    • (2002) Am. J. Neuroradiol. , vol.23 , pp. 1327-1333
    • Ge, Y.1    Grossman, R.I.2    Babb, J.S.3    Rabin, M.L.4    Mannon, L.J.5    Kolson, D.L.6
  • 59
    • 33644649803 scopus 로고    scopus 로고
    • Neurovascular coupling in the normal brain and in hypertension, stroke, and Alzheimer disease
    • Girouard, H. and Iadecola, C. (2006). Neurovascular coupling in the normal brain and in hypertension, stroke, and Alzheimer disease. J. Appl. Physiol. 100, 328-335.
    • (2006) J. Appl. Physiol. , vol.100 , pp. 328-335
    • Girouard, H.1    Iadecola, C.2
  • 60
    • 54049149226 scopus 로고    scopus 로고
    • Changes in cognitive function in human aging
    • (Boca Raton, FL: CRC Press, Taylor & Francis(Group
    • Glisky, E.L. (2007). Changes in Cognitive Function in Human Aging. In Brain aging: Models, methods, and mechanisms, pp. 3-20.(Boca Raton, FL: CRC Press, Taylor & Francis Group).
    • (2007) Brain Aging: Models, Methods, and Mechanisms , pp. 3-20
    • Glisky, E.L.1
  • 62
    • 0029049291 scopus 로고
    • Behavioral disturbance and impairment of executive functions among the elderly
    • Grigsby, J., Kaye, K., and Robbins, L.J. (1995). Behavioral disturbance and impairment of executive functions among the elderly. Arch. Gerontol. Geriatr. 21, 167-177.
    • (1995) Arch. Gerontol. Geriatr. , vol.21 , pp. 167-177
    • Grigsby, J.1    Kaye, K.2    Robbins, L.J.3
  • 63
    • 0026322413 scopus 로고
    • Biological variability of superoxide dismutase, glutathione peroxidase, and catalase in blood
    • Guemouri, L.Y.B.C.G.G., Artur, Y., Herbeth, B., Jeandel, C., Cuny, G., and Siest, G. (1991). Biological variability of superoxide dismutase, glutathione peroxidase, and catalase in blood. Clin. Chem. 37, 1932-1937.
    • (1991) Clin. Chem. , vol.37 , pp. 1932-1937
    • Guemouri, L.Y.B.C.G.G.1    Artur, Y.2    Herbeth, B.3    Jeandel, C.4    Cuny, G.5    Siest, G.6
  • 64
    • 4344649455 scopus 로고    scopus 로고
    • Functional variants in the glutathione peroxidase-1 (GPx-1) gene are associated with increased intima-media thickness of carotid arteries and risk of macrovascular diseases in Japanese type 2 diabetic patients
    • Hamanishi, T., Furuta, H., Kato, H., Doi, A., Tamai, M., Shimomura, H., Sakagashira, S., Nishi, M., Sasaki, H., Sanke, T., and Nanjo, K. (2004). Functional variants in the glutathione peroxidase-1 (GPx-1) gene are associated with increased intima-media thickness of carotid arteries and risk of macrovascular diseases in Japanese type 2 diabetic patients. Diabetes 53, 2455-2460.
    • (2004) Diabetes , vol.53 , pp. 2455-2460
    • Hamanishi, T.1    Furuta, H.2    Kato, H.3    Doi, A.4    Tamai, M.5    Shimomura, H.6    Sakagashira, S.7    Nishi, M.8    Sasaki, H.9    Sanke, T.10    Nanjo, K.11
  • 66
    • 34547628342 scopus 로고    scopus 로고
    • A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition
    • Harris, S.E., Fox, H., Wright, A.F., Hayward, C., Starr, J.M., Whalley, L.J., and Deary, I.J. (2007). A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition. BMC Genet. 8, 43.
    • (2007) BMC Genet. , vol.8 , pp. 43
    • Harris, S.E.1    Fox, H.2    Wright, A.F.3    Hayward, C.4    Starr, J.M.5    Whalley, L.J.6    Deary, I.J.7
  • 67
    • 84903363379 scopus 로고    scopus 로고
    • High-field proton magnetic resonance spectroscopy reveals metabolic effects of normal brain aging
    • Harris, J.L., Yeh, H., Swerdlow, R.H., Choi, I., Lee, P., and Brooks, W.M. (2014). High-field proton magnetic resonance spectroscopy reveals metabolic effects of normal brain aging. Neurobiol. Aging 35, 1686.
    • (2014) Neurobiol. Aging , vol.35 , pp. 1686
    • Harris, J.L.1    Yeh, H.2    Swerdlow, R.H.3    Choi, I.4    Lee, P.5    Brooks, W.M.6
  • 68
    • 0033828113 scopus 로고    scopus 로고
    • Glutathione S-transferase polymorphisms and their biological consequences
    • Hayes, J.D. and Strange, R.C. (2000). Glutathione S-transferase polymorphisms and their biological consequences. Pharmacology 61, 154-166.
    • (2000) Pharmacology , vol.61 , pp. 154-166
    • Hayes, J.D.1    Strange, R.C.2
  • 70
    • 1942453876 scopus 로고    scopus 로고
    • Differential vulnerability of anterior white matter in nondemented aging with minimal acceleration in dementia of the Alzheimer type: Evidence from diffusion tensor imaging
    • Head, D., Buckner, R.L., Shimony, J.S., Williams, L.E., Akbudak, E., Conturo, T.E., McAvoy, M., Morris, J.C., and Snyder, A.Z. (2004). Differential vulnerability of anterior white matter in nondemented aging with minimal acceleration in dementia of the Alzheimer type: Evidence from diffusion tensor imaging. Cereb. Cortex 14, 410-423.
    • (2004) Cereb. Cortex , vol.14 , pp. 410-423
    • Head, D.1    Buckner, R.L.2    Shimony, J.S.3    Williams, L.E.4    Akbudak, E.5    Conturo, T.E.6    McAvoy, M.7    Morris, J.C.8    Snyder, A.Z.9
  • 72
    • 0141642104 scopus 로고    scopus 로고
    • Glutathione peroxidase overexpression inhibits cytochrome C release and proapoptotic mediators to protect neurons from experimental stroke
    • Hoehn, B., Yenari, M.A., Sapolsky, R.M., and Steinberg, G.K. (2003). Glutathione peroxidase overexpression inhibits cytochrome C release and proapoptotic mediators to protect neurons from experimental stroke. Stroke 34, 2489-2494.
    • (2003) Stroke , vol.34 , pp. 2489-2494
    • Hoehn, B.1    Yenari, M.A.2    Sapolsky, R.M.3    Steinberg, G.K.4
  • 74
    • 77955298346 scopus 로고    scopus 로고
    • Manganese superoxide dismutase versus p53: The mitochondrial center
    • Holley, A.K., Dhar, S.K., and St Clair, D.K. (2010). Manganese superoxide dismutase versus p53: The mitochondrial center. Ann. N.Y. Acad. Sci. 1201, 72-78.
    • (2010) Ann. N.Y. Acad. Sci. , vol.1201 , pp. 72-78
    • Holley, A.K.1    Dhar, S.K.2    St Clair, D.K.3
  • 75
    • 1842590611 scopus 로고    scopus 로고
    • The sensitivity of dual-task performance to cognitive status in aging
    • Holtzer, R., Burright, R.G., and Donovick, P.J. (2004). The sensitivity of dual-task performance to cognitive status in aging. J. Int. Neuropsychol. Soc. 10, 230-238.
    • (2004) J. Int. Neuropsychol. Soc. , vol.10 , pp. 230-238
    • Holtzer, R.1    Burright, R.G.2    Donovick, P.J.3
  • 76
    • 84925732137 scopus 로고    scopus 로고
    • Neurovascular Regulation in the Ischemic Brain. Antioxidants & redox signaling. Jozefczak, M., Remans, T., Vangronsveld, J., and Cuypers, A. (2012). Glutathione is a key player in metal-induced oxidative stress defenses
    • Jackman, K., & Iadecola, C. (2013). Neurovascular Regulation in the Ischemic Brain. Antioxidants & redox signaling. Jozefczak, M., Remans, T., Vangronsveld, J., and Cuypers, A. (2012). Glutathione is a key player in metal-induced oxidative stress defenses. Int. J. Mol. Sci. 13, 3145-3175.
    • (2013) Int. J. Mol. Sci. , vol.13 , pp. 3145-3175
    • Jackman, K.1    Iadecola, C.2
  • 78
    • 77952288461 scopus 로고    scopus 로고
    • Neural and vascular variability and the fMRI-BOLD response in normal aging
    • Kannurpatti, S.S., Motes, M.A., Rypma, B., and Biswal, B.B. (2010). Neural and vascular variability and the fMRI-BOLD response in normal aging. Magnet. Reson. Imaging 28, 466-476.
    • (2010) Magnet. Reson. Imaging , vol.28 , pp. 466-476
    • Kannurpatti, S.S.1    Motes, M.A.2    Rypma, B.3    Biswal, B.B.4
  • 79
    • 48149098204 scopus 로고    scopus 로고
    • Classification of white matter lesions on magnetic resonance imaging in elderly persons
    • Kim, K.W., MacFall, J.R., and Payne, M.E. (2008). Classification of white matter lesions on magnetic resonance imaging in elderly persons. Biol. Psychiatry 64, 273-280.
    • (2008) Biol. Psychiatry , vol.64 , pp. 273-280
    • Kim, K.W.1    MacFall, J.R.2    Payne, M.E.3
  • 80
    • 33846241298 scopus 로고    scopus 로고
    • Sources and targets of reactive oxygen species in synaptic plasticity and memory
    • Kishida, K.T. and Klann, E. (2007). Sources and targets of reactive oxygen species in synaptic plasticity and memory. Antioxid. Redox Signal. 9, 233-244.
    • (2007) Antioxid. Redox Signal. , vol.9 , pp. 233-244
    • Kishida, K.T.1    Klann, E.2
  • 81
    • 0036785151 scopus 로고    scopus 로고
    • Role of reactive oxygen species in hippocampal long-term potentiation: Contributory or inhibitory?
    • Knapp, L.T. and Klann, E. (2002). Role of reactive oxygen species in hippocampal long-term potentiation: Contributory or inhibitory? J. Neurosci. Res. 70, 1-7.
    • (2002) J. Neurosci. Res. , vol.70 , pp. 1-7
    • Knapp, L.T.1    Klann, E.2
  • 82
    • 26244454791 scopus 로고    scopus 로고
    • Oxidative stress promotes endothelial cell apoptosis and loss of microvessels in the spontaneously hypertensive rats
    • Kobayashi, N., DeLano, F.A., and Schmid-Schönbein, G.W. (2005). Oxidative stress promotes endothelial cell apoptosis and loss of microvessels in the spontaneously hypertensive rats. Artheroscler. Thromb. Vasc. Biol. 25, 2114-2121.
    • (2005) Artheroscler. Thromb. Vasc. Biol. , vol.25 , pp. 2114-2121
    • Kobayashi, N.1    DeLano, F.A.2    Schmid-Schönbein, G.W.3
  • 83
    • 34047203065 scopus 로고    scopus 로고
    • Elevated glucose concentrations promote receptor-independent activation of adherent human neutrophils: An experimental and computational approach
    • Kummer, U., Zobeley, J., Brasen, J.C., Fahmy, R., Kindzelskii, A.L., Petty, A.R., Clark, A. J., and Petty, H. R. (2007). Elevated glucose concentrations promote receptor-independent activation of adherent human neutrophils: An experimental and computational approach. Biophys. J. 92, 2597-2607.
    • (2007) Biophys. J. , vol.92 , pp. 2597-2607
    • Kummer, U.1    Zobeley, J.2    Brasen, J.C.3    Fahmy, R.4    Kindzelskii, A.L.5    Petty, A.R.6    Clark, A.J.7    Petty, H.R.8
  • 84
    • 45749088869 scopus 로고    scopus 로고
    • Glutathione peroxidase 1 Pro198Leu variant contributes to the metabolic syndrome in men in a large Japanese cohort
    • Kuzuya, M., Ando, F., Iguchi, A., and Shimokata, H. (2008). Glutathione peroxidase 1 Pro198Leu variant contributes to the metabolic syndrome in men in a large Japanese cohort. Am. J. Clin. Nutr. 87, 1939-1944.
    • (2008) Am. J. Clin. Nutr. , vol.87 , pp. 1939-1944
    • Kuzuya, M.1    Ando, F.2    Iguchi, A.3    Shimokata, H.4
  • 85
    • 0032777902 scopus 로고    scopus 로고
    • P53 Induction by tumor necrosis factor-Á and involvement of p53 in cell death of human oligodendrocytes
    • Ladiwala, U., Li, H., Antel, J.P., and Nalbantoglu, J. (1999). p53 Induction by tumor necrosis factor-á and involvement of p53 in cell death of human oligodendrocytes. J. Neurochem. 73, 605-611.
    • (1999) J. Neurochem. , vol.73 , pp. 605-611
    • Ladiwala, U.1    Li, H.2    Antel, J.P.3    Nalbantoglu, J.4
  • 86
    • 0032779847 scopus 로고    scopus 로고
    • Manganese-containing superoxide dismutase signal sequence polymorphism associated with sporadic motor neuron disease
    • Landeghem, G. F., Tabatabaie, P., Beckman, G., Beckman, L., & Andersen, P. M. (1999). Manganese-containing superoxide dismutase signal sequence polymorphism associated with sporadic motor neuron disease. European Journal of Neurology, 6, 639-644.
    • (1999) European Journal of Neurology , vol.6 , pp. 639-644
    • Landeghem, G.F.1    Tabatabaie, P.2    Beckman, G.3    Beckman, L.4    Andersen, P.M.5
  • 87
    • 0036172324 scopus 로고    scopus 로고
    • Age-associated cardiovascular changes in health: Impact on cardiovascular disease in older persons
    • Lakatta, E.G. (2002). Age-associated cardiovascular changes in health: Impact on cardiovascular disease in older persons. Heart Fail. Rev. 7, 29-49.
    • (2002) Heart Fail. Rev. , vol.7 , pp. 29-49
    • Lakatta, E.G.1
  • 89
    • 0032779847 scopus 로고    scopus 로고
    • Manganese-containing superoxide dismutase signal sequence polymorphism associated with sporadic motor neuron disease
    • Landeghem, G.F., Tabatabaie, P., Beckman, G., Beckman, L., and Andersen, P.M. (1999). Manganese-containing superoxide dismutase signal sequence polymorphism associated with sporadic motor neuron disease. Eur. J. Neurol. 6, 639-644.
    • (1999) Eur. J. Neurol. , vol.6 , pp. 639-644
    • Landeghem, G.F.1    Tabatabaie, P.2    Beckman, G.3    Beckman, L.4    Andersen, P.M.5
  • 91
    • 34247127167 scopus 로고    scopus 로고
    • Mitochondrial DNA repair: A critical player in the response of cells of the CNS to genotoxic insults
    • LeDoux, S. P., Druzhyna, N. M., Hollensworth, S. B., Harrison, J. F., & Wilson, G. L. (2007). Mitochondrial DNA repair: A critical player in the response of cells of the CNS to genotoxic insults. Neuroscience, 145, 1249-1259.
    • (2007) Neuroscience , vol.145 , pp. 1249-1259
    • LeDoux, S.P.1    Druzhyna, N.M.2    Hollensworth, S.B.3    Harrison, J.F.4    Wilson, G.L.5
  • 92
    • 33750347347 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
    • Lin, M.T. and Beal, M.F. (2006). Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 443, 787-795.
    • (2006) Nature , vol.443 , pp. 787-795
    • Lin, M.T.1    Beal, M.F.2
  • 93
    • 33747884571 scopus 로고    scopus 로고
    • Variability in cognitive aging: From taxonomy to theory
    • New York: Oxford University Press, Inc
    • Lindenberger, U. and von Oertzen, T. (2006). Variability in cognitive aging: From taxonomy to theory. Lifespan Cogn. Mech. Change 297-314. New York: Oxford University Press, Inc.
    • (2006) Lifespan Cogn. Mech. Change , pp. 297-314
    • Lindenberger, U.1    Von Oertzen, T.2
  • 94
    • 0029917723 scopus 로고    scopus 로고
    • Effect of liver cirrhosis and age on the glutathione concentration in the plasma, erythrocytes, and gastric mucosa of man
    • Loguercio, C., Taranto, D., Vitale, L.M., Beneduce, F., and Del Vecchio Blanco, C. (1996). Effect of liver cirrhosis and age on the glutathione concentration in the plasma, erythrocytes, and gastric mucosa of man. Free Radical Biol. Med. 20, 483-488.
    • (1996) Free Radical Biol. Med. , vol.20 , pp. 483-488
    • Loguercio, C.1    Taranto, D.2    Vitale, L.M.3    Beneduce, F.4    Del Vecchio Blanco, C.5
  • 96
    • 0032924640 scopus 로고    scopus 로고
    • Oxidative stress in brain ischemia
    • Love, S. (1999). Oxidative stress in brain ischemia. Brain Pathol. 9, 119-131.
    • (1999) Brain Pathol. , vol.9 , pp. 119-131
    • Love, S.1
  • 97
    • 3042631024 scopus 로고    scopus 로고
    • Gene regulation and DNA damage in the ageing human brain
    • Lu, T., Pan, Y., Kao, S.Y., Li, C., Kohane, I., Chan, J., and Yankner, B.A. (2004). Gene regulation and DNA damage in the ageing human brain. Nature 429, 883-891.
    • (2004) Nature , vol.429 , pp. 883-891
    • Lu, T.1    Pan, Y.2    Kao, S.Y.3    Li, C.4    Kohane, I.5    Chan, J.6    Yankner, B.A.7
  • 98
    • 80052000670 scopus 로고    scopus 로고
    • Glutathione peroxidase- 1 in health and disease: From molecular mechanisms to therapeutic opportunities
    • Lubos, E., Loscalzo, J., and Handy, D.E. (2011). Glutathione peroxidase- 1 in health and disease: From molecular mechanisms to therapeutic opportunities. Antioxid. Redox. Signal. 15, 1957-1997.
    • (2011) Antioxid. Redox. Signal. , vol.15 , pp. 1957-1997
    • Lubos, E.1    Loscalzo, J.2    Handy, D.E.3
  • 99
    • 0031750968 scopus 로고    scopus 로고
    • Analysis of the mechanisms underlying the agerelated impairment in long-term potentiation in the rat
    • Lynch, M.A. (1998). Analysis of the mechanisms underlying the agerelated impairment in long-term potentiation in the rat. Rev. Neurosci. 9, 169-202.
    • (1998) Rev. Neurosci. , vol.9 , pp. 169-202
    • Lynch, M.A.1
  • 100
    • 33746323949 scopus 로고    scopus 로고
    • Intra-individual variability in behavior: Links to brain structure, neurotransmission and neuronal activity
    • MacDonald, S.W., Nyberg, L., and Bäckman, L. (2006). Intra-individual variability in behavior: Links to brain structure, neurotransmission and neuronal activity. Trends Neurosci. 29, 474-480.
    • (2006) Trends Neurosci. , vol.29 , pp. 474-480
    • MacDonald, S.W.1    Nyberg, L.2    Bäckman, L.3
  • 102
    • 62949136613 scopus 로고    scopus 로고
    • Longitudinal follow-up of individual white matter hyperintensities in a large cohort of elderly
    • Maillard, P., Crivello, F., Dufouil, C., Tzourio-Mazoyer, N., Tzourio, C., and Mazoyer, B. (2009). Longitudinal follow-up of individual white matter hyperintensities in a large cohort of elderly. Neuroradiology 51, 209-220.
    • (2009) Neuroradiology , vol.51 , pp. 209-220
    • Maillard, P.1    Crivello, F.2    Dufouil, C.3    Tzourio-Mazoyer, N.4    Tzourio, C.5    Mazoyer, B.6
  • 103
    • 62649155340 scopus 로고    scopus 로고
    • Glutathione S-transferase T1-and M1-null genotypes and coronary artery disease risk in patients with type 2 diabetes mellitus
    • Manfredi, S., Calvi, D., del Fiandra, M., Botto, N., Biagini, A., and Andreassi, M.G. (2009). Glutathione S-transferase T1-and M1-null genotypes and coronary artery disease risk in patients with type 2 diabetes mellitus. Cardiovasc. Pharmacogen. 10, 29-34.
    • (2009) Cardiovasc. Pharmacogen. , vol.10 , pp. 29-34
    • Manfredi, S.1    Calvi, D.2    Del Fiandra, M.3    Botto, N.4    Biagini, A.5    Andreassi, M.G.6
  • 104
    • 27644485874 scopus 로고    scopus 로고
    • Oxidative stress in brain aging, neurodegenerative and vascular diseases: An overview
    • Mariani, E., Polidori, M.C., Cherubini, A., and Mecocci, P. (2005). Oxidative stress in brain aging, neurodegenerative and vascular diseases: An overview. J. Chromatogr. B 827, 65-75.
    • (2005) J. Chromatogr. B , vol.827 , pp. 65-75
    • Mariani, E.1    Polidori, M.C.2    Cherubini, A.3    Mecocci, P.4
  • 105
    • 0038467307 scopus 로고    scopus 로고
    • Marked loss of myelinated nerve fibers in the human brain with age
    • Marner, L., Nyengaard, J.R., Tang, Y., and Pakkenberg, B. (2003). Marked loss of myelinated nerve fibers in the human brain with age. J. Comp. Neurol. 462, 144-152.
    • (2003) J. Comp. Neurol. , vol.462 , pp. 144-152
    • Marner, L.1    Nyengaard, J.R.2    Tang, Y.3    Pakkenberg, B.4
  • 106
    • 25144482448 scopus 로고    scopus 로고
    • Novel mechanisms of natural antioxidant compounds in biological systems: Involvement of glutathione and glutathione-related enzymes
    • Masella, R., Di Benedetto, R., Varì, R., Filesi, C., and Giovannini, C. (2005). Novel mechanisms of natural antioxidant compounds in biological systems: Involvement of glutathione and glutathione-related enzymes. J. Nutr. Biochem. 16, 577-586.
    • (2005) J. Nutr. Biochem. , vol.16 , pp. 577-586
    • Masella, R.1    Di Benedetto, R.2    Varì, R.3    Filesi, C.4    Giovannini, C.5
  • 107
    • 0036304650 scopus 로고    scopus 로고
    • Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior
    • Mattson, M.P., Chan, S.L., and Duan, W. (2002). Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior. Physiol. Rev. 82, 637-672.
    • (2002) Physiol. Rev. , vol.82 , pp. 637-672
    • Mattson, M.P.1    Chan, S.L.2    Duan, W.3
  • 108
    • 82355160899 scopus 로고    scopus 로고
    • Heightened inflammasome activation is linked to age-related cognitive impairment in Fischer 344 rats
    • Mawhinney, L.J., de Rivero Vaccari, J.P., Dale, G.A., Keane, R.W., and Bramlett, H.M. (2011). Heightened inflammasome activation is linked to age-related cognitive impairment in Fischer 344 rats. BMC Neurosci. 12, 123.
    • (2011) BMC Neurosci. , vol.12 , pp. 123
    • Mawhinney, L.J.1    De Rivero Vaccari, J.P.2    Dale, G.A.3    Keane, R.W.4    Bramlett, H.M.5
  • 109
    • 51849102869 scopus 로고    scopus 로고
    • The life, death, and replacement of oligodendrocytes in the adult CNS
    • McTigue, D.M., and Tripathi, R.B. (2008). The life, death, and replacement of oligodendrocytes in the adult CNS. J. Neurochem. 107, 1-19.
    • (2008) J. Neurochem. , vol.107 , pp. 1-19
    • McTigue, D.M.1    Tripathi, R.B.2
  • 112
    • 0019223192 scopus 로고
    • Variation with age in the volumes of grey and white matter in the cerebral hemispheres of man: Measurements with an image analyser
    • Miller, A.K.H., Alston, R.L., and Corsellis, J.A.N. (1980). Variation with age in the volumes of grey and white matter in the cerebral hemispheres of man: Measurements with an image analyser. Neuropath. Appl. Neurobiol. 6, 119-132.
    • (1980) Neuropath. Appl. Neurobiol. , vol.6 , pp. 119-132
    • Miller, A.K.H.1    Alston, R.L.2    Corsellis, J.A.N.3
  • 113
    • 0025877740 scopus 로고
    • Changes in cognitive functioning associated with normal aging
    • Mitrushina, M. and Satz, P. (1991). Changes in cognitive functioning associated with normal aging. Arch. Clin. Neurol. 6, 49-60.
    • (1991) Arch. Clin. Neurol. , vol.6 , pp. 49-60
    • Mitrushina, M.1    Satz, P.2
  • 114
    • 0035241613 scopus 로고    scopus 로고
    • Hydrogen peroxide induces rapid digestion of oligodendrocyte chromatin into high molecular weight fragments
    • Mouzannar, R., Miric, S.J., Wiggins, R.C., and Konat, G.W. (2001). Hydrogen peroxide induces rapid digestion of oligodendrocyte chromatin into high molecular weight fragments. Neurochem. Int. 38, 9-15.
    • (2001) Neurochem. Int. , vol.38 , pp. 9-15
    • Mouzannar, R.1    Miric, S.J.2    Wiggins, R.C.3    Konat, G.W.4
  • 117
    • 25144454460 scopus 로고    scopus 로고
    • Brain white matter hyperintensities: Relative importance of vascular risk factors in nondemented elderly people 1
    • Murray, A. D., Staff, R. T., Shenkin, S. D., Deary, I. J., Starr, J. M., & Whalley, L. J. (2005). Brain White Matter Hyperintensities: Relative Importance of Vascular Risk Factors in Nondemented Elderly People 1. Radiology, 237, 251-257.
    • (2005) Radiology , vol.237 , pp. 251-257
    • Murray, A.D.1    Staff, R.T.2    Shenkin, S.D.3    Deary, I.J.4    Starr, J.M.5    Whalley, L.J.6
  • 118
    • 79961207643 scopus 로고    scopus 로고
    • Evaluation of markers of oxidative stress, antioxidant function and astrocytic proliferation in the striatum and frontal cortex of Parkinson's disease brains
    • Mythri, R.B., Venkateshappa, C., Harish, G., Mahadevan, A., Muthane, U.B., Yasha, T.C., Srinivas Bharath, M.M., and Shankar, S.K. (2011). Evaluation of markers of oxidative stress, antioxidant function and astrocytic proliferation in the striatum and frontal cortex of Parkinson's disease brains. Neurochem. Res. 36, 1452-1463.
    • (2011) Neurochem. Res. , vol.36 , pp. 1452-1463
    • Mythri, R.B.1    Venkateshappa, C.2    Harish, G.3    Mahadevan, A.4    Muthane, U.B.5    Yasha, T.C.6    Srinivas Bharath, M.M.7    Shankar, S.K.8
  • 119
    • 79961207643 scopus 로고    scopus 로고
    • Evaluation of markers of oxidative stress, antioxidant function and astrocytic proliferation in the striatum and frontal cortex of Parkinson's disease brains
    • Mythri, R. B., Venkateshappa, C., Harish, G., Mahadevan, A., Muthane, U. B., Yasha, T. C., Bharath, M.M., and Shankar, S. K. (2011). Evaluation of markers of oxidative stress, antioxidant function and astrocytic proliferation in the striatum and frontal cortex of Parkinson's disease brains. Neurochemical research, 36, 1452-1463.
    • (2011) Neurochemical research , vol.36 , pp. 1452-1463
    • Mythri, R.B.1    Venkateshappa, C.2    Harish, G.3    Mahadevan, A.4    Muthane, U.B.5    Yasha, T.C.6    Bharath, M.M.7    Shankar, S.K.8
  • 121
    • 43449095741 scopus 로고    scopus 로고
    • The early life origins of vascular ageing and cardiovascular risk: The EVA syndrome
    • Nilsson, P.M., Lurbe, E., and Laurent, S. (2008). The early life origins of vascular ageing and cardiovascular risk: The EVA syndrome. J. Hypertens. 26, 1049-1057.
    • (2008) J. Hypertens. , vol.26 , pp. 1049-1057
    • Nilsson, P.M.1    Lurbe, E.2    Laurent, S.3
  • 122
    • 0025630001 scopus 로고
    • Brain magnetic resonance imaging with contrast dependent on blood oxygenation
    • Ogawa, S., Lee, T.M., Kay, A.R., and Tank, D.W. (1990). Brain magnetic resonance imaging with contrast dependent on blood oxygenation. Proc. Natl. Acad. Sci. 87, 9868-9872.
    • (1990) Proc. Natl. Acad. Sci. , vol.87 , pp. 9868-9872
    • Ogawa, S.1    Lee, T.M.2    Kay, A.R.3    Tank, D.W.4
  • 123
    • 84856211599 scopus 로고    scopus 로고
    • Reactive oxygen species and ischemic cerebrovascular disease
    • Olmez, I. and Ozyurt, H. (2012). Reactive oxygen species and ischemic cerebrovascular disease. Neurochem. Int. 60, 208-212.
    • (2012) Neurochem. Int. , vol.60 , pp. 208-212
    • Olmez, I.1    Ozyurt, H.2
  • 125
    • 37549056972 scopus 로고    scopus 로고
    • Reduced mitochondrial SOD displays mortality characteristics reminiscent of natural aging
    • Paul, A., Belton, A., Nag, S., Martin, I., Grotewiel, M.S., and Duttaroy, A. (2007). Reduced mitochondrial SOD displays mortality characteristics reminiscent of natural aging. Mech. Aging Dev. 128, 706-716.
    • (2007) Mech. Aging Dev. , vol.128 , pp. 706-716
    • Paul, A.1    Belton, A.2    Nag, S.3    Martin, I.4    Grotewiel, M.S.5    Duttaroy, A.6
  • 126
    • 44449093153 scopus 로고    scopus 로고
    • Glutathione peroxidase 1 C593T polymorphism is associated with lobar intracerebral hemorrhage
    • Pera, J., Slowik, A., Dziedzic, T., Pulyk, R., Wloch, D., and Szczudlik, A. (2008). Glutathione peroxidase 1 C593T polymorphism is associated with lobar intracerebral hemorrhage. Cerebrovasc. Dis. 25, 445-449.
    • (2008) Cerebrovasc. Dis. , vol.25 , pp. 445-449
    • Pera, J.1    Slowik, A.2    Dziedzic, T.3    Pulyk, R.4    Wloch, D.5    Szczudlik, A.6
  • 127
    • 0025670273 scopus 로고
    • Blood activity of Cu/Zn superoxide dismutase, glutathione peroxidase and catalase in Alzheimer's disease: A case-control study
    • Perrin, R., Briancon, S., Jeandel, C., Artur, Y., Minn, A., Penin, F., and Siest, G. (1990). Blood activity of Cu/Zn superoxide dismutase, glutathione peroxidase and catalase in Alzheimer's disease: A case-control study. Gerontology 36, 306-313.
    • (1990) Gerontology , vol.36 , pp. 306-313
    • Perrin, R.1    Briancon, S.2    Jeandel, C.3    Artur, Y.4    Minn, A.5    Penin, F.6    Siest, G.7
  • 128
    • 0242658661 scopus 로고    scopus 로고
    • The effects of normal aging on myelin and nerve fibers: A review
    • Peters, A. (2002). The effects of normal aging on myelin and nerve fibers: A review. Journal of neurocytology, 31, 581-593.
    • (2002) Journal of neurocytology , vol.31 , pp. 581-593
    • Peters, A.1
  • 129
    • 84864386391 scopus 로고    scopus 로고
    • A review of the structural alterations in the cerebral hemispheres of the aging rhesus monkey
    • Peters, A., & Kemper, T. (2012). A review of the structural alterations in the cerebral hemispheres of the aging rhesus monkey. Neurobiology of aging, 33, 2357-2372.
    • (2012) Neurobiology of aging , vol.33 , pp. 2357-2372
    • Peters, A.1    Kemper, T.2
  • 130
    • 0028017540 scopus 로고
    • A quantitative magnetic resonance imaging study of changes in brain morphology from infancy to late adulthood
    • Pfefferbaum, A., Mathalon, D.H., Sullivan, E.V., Rawles, J.M., Zipursky, R.B., and Lim, K.O. (1994). A quantitative magnetic resonance imaging study of changes in brain morphology from infancy to late adulthood. Arch. Neurol. 51, 874-887.
    • (1994) Arch. Neurol. , vol.51 , pp. 874-887
    • Pfefferbaum, A.1    Mathalon, D.H.2    Sullivan, E.V.3    Rawles, J.M.4    Zipursky, R.B.5    Lim, K.O.6
  • 132
    • 57049169723 scopus 로고    scopus 로고
    • Cellular glutathione peroxidase in human brain: Cellular distribution, and its potential role in the degradation of Lewy bodies in Parkinson's disease and dementia with Lewy bodies
    • Power, J.H. and Blumbergs, P.C. (2009). Cellular glutathione peroxidase in human brain: Cellular distribution, and its potential role in the degradation of Lewy bodies in Parkinson's disease and dementia with Lewy bodies. Acta Neuropath. 117, 63-73.
    • (2009) Acta Neuropath. , vol.117 , pp. 63-73
    • Power, J.H.1    Blumbergs, P.C.2
  • 135
    • 0029055175 scopus 로고
    • Oxidative processes and antioxidative defense mechanisms in the aging brain
    • Reiter, R.J. (1995). Oxidative processes and antioxidative defense mechanisms in the aging brain. FASEB J. 9, 526-533.
    • (1995) FASEB J. , vol.9 , pp. 526-533
    • Reiter, R.J.1
  • 137
    • 84867005236 scopus 로고    scopus 로고
    • Measurement of nitric oxide and reactive oxygen species in the vascular wall
    • Rodriguez-Rodriguez, R., & Simonsen, U. (2012). Measurement of nitric oxide and reactive oxygen species in the vascular wall. Current Analytical Chemistry, 8, 485-494.
    • (2012) Current Analytical Chemistry , vol.8 , pp. 485-494
    • Rodriguez-Rodriguez, R.1    Simonsen, U.2
  • 138
    • 0035871761 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy of the human brain
    • Ross, B. and Bluml, S. (2001). Magnetic resonance spectroscopy of the human brain. Anat. Record. 265, 54-84.
    • (2001) Anat. Record. , vol.265 , pp. 54-84
    • Ross, B.1    Bluml, S.2
  • 139
    • 0034534995 scopus 로고    scopus 로고
    • Interleukin 1 in the brain: Biology, pathology and therapeutic target
    • Rothwell, N.J. and Luheshi, G.N. (2000). Interleukin 1 in the brain: Biology, pathology and therapeutic target. Trends Neurosci. 23, 618-625.
    • (2000) Trends Neurosci. , vol.23 , pp. 618-625
    • Rothwell, N.J.1    Luheshi, G.N.2
  • 141
    • 34249718795 scopus 로고    scopus 로고
    • Markers of oxidative stress in erythrocytes during aging in humans
    • Rizvi, S. I., & Maurya, P. K. (2007). Markers of oxidative stress in erythrocytes during aging in humans. Annals of the New York Academy of Sciences, 1100, 373-382.
    • (2007) Annals of the New York Academy of Sciences , vol.1100 , pp. 373-382
    • Rizvi, S.I.1    Maurya, P.K.2
  • 143
    • 65549139675 scopus 로고    scopus 로고
    • Regulation of the aging process by autophagy
    • Salminen, A. and Kaarniranta, K. (2009). Regulation of the aging process by autophagy. Trends Mol. Med. 15, 217-224.
    • (2009) Trends Mol. Med. , vol.15 , pp. 217-224
    • Salminen, A.1    Kaarniranta, K.2
  • 144
    • 41749098381 scopus 로고    scopus 로고
    • White matter hyperintensities in mid-adult life
    • Sachdev, P., Chen, X., & Wen, W. (2008). White matter hyperintensities in mid-adult life. Current opinion in psychiatry, 21, 268-274.
    • (2008) Current opinion in psychiatry , vol.21 , pp. 268-274
    • Sachdev, P.1    Chen, X.2    Wen, W.3
  • 145
    • 84863329778 scopus 로고    scopus 로고
    • Inflammaging: Disturbed interplay between autophagy and inflammasomes
    • Salminen, A., Kaarniranta, K., and Kauppinen, A. (2012). Inflammaging: Disturbed interplay between autophagy and inflammasomes. Aging 4, 166.
    • (2012) Aging , vol.4 , pp. 166
    • Salminen, A.1    Kaarniranta, K.2    Kauppinen, A.3
  • 146
    • 4043118287 scopus 로고    scopus 로고
    • What and when of cognitive aging
    • Salthouse, T.A. (2004). What and when of cognitive aging. Curr. Dir. Psychol. Sci. 13, 140-144.
    • (2004) Curr. Dir. Psychol. Sci. , vol.13 , pp. 140-144
    • Salthouse, T.A.1
  • 148
    • 8444227821 scopus 로고    scopus 로고
    • Reactive oxygen species and synaptic plasticity in the aging hippocampus
    • Serrano, F. and Klann, E. (2004). Reactive oxygen species and synaptic plasticity in the aging hippocampus. Ageing Res. Rev. 3, 431-443.
    • (2004) Ageing Res. Rev. , vol.3 , pp. 431-443
    • Serrano, F.1    Klann, E.2
  • 149
    • 1542619261 scopus 로고    scopus 로고
    • Antioxidant role of glutathione S transferases: Protection against oxidant toxicity and regulation of stress-mediated apoptosis
    • Sharma, R., Yang, Y., Sharma, A., Awasthi, S., and Awasthi, Y.C. (2004). Antioxidant role of glutathione S transferases: Protection against oxidant toxicity and regulation of stress-mediated apoptosis. Antioxid. Redox. Signal. 6, 289-300.
    • (2004) Antioxid. Redox. Signal. , vol.6 , pp. 289-300
    • Sharma, R.1    Yang, Y.2    Sharma, A.3    Awasthi, S.4    Awasthi, Y.C.5
  • 150
    • 0030582372 scopus 로고    scopus 로고
    • Structural dimorphism in the mitochondrial targeting sequence in the human manganese superoxide dismutase gene: A predictive evidence for conformational change to influence mitochondrial transport and a study of allelic association in Parkinson's disease
    • Shimoda-Matsubayashi, S., Matsumine, H., Kobayashi, T., Nakagawa- Hattori, Y., Shimizu, Y., and Mizuno, Y. (1996). Structural dimorphism in the mitochondrial targeting sequence in the human manganese superoxide dismutase gene: A predictive evidence for conformational change to influence mitochondrial transport and a study of allelic association in Parkinson's disease. Biochem. Biophys. Res. Commun. 226, 561-565.
    • (1996) Biochem. Biophys. Res. Commun. , vol.226 , pp. 561-565
    • Shimoda-Matsubayashi, S.1    Matsumine, H.2    Kobayashi, T.3    Nakagawa- Hattori, Y.4    Shimizu, Y.5    Mizuno, Y.6
  • 151
    • 79956203683 scopus 로고    scopus 로고
    • Vascular mechanisms in the pathogenesis of stroke
    • Sierra, C., Coca, A., and Schiffrin, E.L. (2011). Vascular mechanisms in the pathogenesis of stroke. Curr. Hypertens. Rep. 13, 200-207.
    • (2011) Curr. Hypertens. Rep. , vol.13 , pp. 200-207
    • Sierra, C.1    Coca, A.2    Schiffrin, E.L.3
  • 152
    • 0032950964 scopus 로고    scopus 로고
    • Demyelination: The role of reactive oxygen and nitrogen species
    • Smith, K.J., Kapoor, R., and Felts, P.A. (1999). Demyelination: The role of reactive oxygen and nitrogen species. Brain Pathol. 9, 69-92.
    • (1999) Brain Pathol. , vol.9 , pp. 69-92
    • Smith, K.J.1    Kapoor, R.2    Felts, P.A.3
  • 153
    • 57349134532 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy of the brain: Review of metabolites and clinical applications
    • Soares, D.P. and Law, M. (2009). Magnetic resonance spectroscopy of the brain: Review of metabolites and clinical applications. Clin. Radiol. 64, 12-21.
    • (2009) Clin. Radiol. , vol.64 , pp. 12-21
    • Soares, D.P.1    Law, M.2
  • 154
    • 63149135685 scopus 로고    scopus 로고
    • The Mn-superoxide dismutase single nucleotide polymorphism rs4880 and the glutathione peroxidase 1 single nucleotide polymorphism rs1050450 are associated with aging and longevity in the oldest old
    • Soerensen, M., Christensen, K., Stevnsner, T., and Christiansen, L. (2009). The Mn-superoxide dismutase single nucleotide polymorphism rs4880 and the glutathione peroxidase 1 single nucleotide polymorphism rs1050450 are associated with aging and longevity in the oldest old. Mech. Aging Dev. 130, 308-314.
    • (2009) Mech. Aging Dev. , vol.130 , pp. 308-314
    • Soerensen, M.1    Christensen, K.2    Stevnsner, T.3    Christiansen, L.4
  • 155
    • 0242300687 scopus 로고    scopus 로고
    • High prevalence of white matter hyperintensities in normal aging: Relation to blood pressure and cognition
    • Söderlund, H., Nyberg, L., Adolfsson, R., Nilsson, L. G., & Launer, L. J. (2003). High prevalence of white matter hyperintensities in normal aging: Relation to blood pressure and cognition. Cortex, 39, 1093-1105.
    • (2003) Cortex , vol.39 , pp. 1093-1105
    • Söderlund, H.1    Nyberg, L.2    Adolfsson, R.3    Nilsson, L.G.4    Launer, L.J.5
  • 157
    • 47649095408 scopus 로고    scopus 로고
    • Genetic variant in glutathione peroxidase 1 gene is associated with an increased risk of coronary artery disease in a Chinese population
    • Tang, N.P., Wang, L.S., Yang, L., Gu, H.J., Sun, Q.M., Cong, R.H., Zhou, B., Zhu, H.J., and Wang, B. (2008). Genetic variant in glutathione peroxidase 1 gene is associated with an increased risk of coronary artery disease in a Chinese population. Clin. Chim. Acta. 395, 89-93.
    • (2008) Clin. Chim. Acta. , vol.395 , pp. 89-93
    • Tang, N.P.1    Wang, L.S.2    Yang, L.3    Gu, H.J.4    Sun, Q.M.5    Cong, R.H.6    Zhou, B.7    Zhu, H.J.8    Wang, B.9
  • 160
    • 3242725278 scopus 로고    scopus 로고
    • Diffusion tensor imaging detects early Wallerian degeneration of the pyramidal tract after ischemic stroke
    • Thomalla, G., Glauche, V., Koch, M.A., Beaulieu, C., Weiller, C., and Röther, J. (2004). Diffusion tensor imaging detects early Wallerian degeneration of the pyramidal tract after ischemic stroke. Neuroimage 22, 1767-1774.
    • (2004) Neuroimage , vol.22 , pp. 1767-1774
    • Thomalla, G.1    Glauche, V.2    Koch, M.A.3    Beaulieu, C.4    Weiller, C.5    Röther, J.6
  • 161
    • 0033525375 scopus 로고    scopus 로고
    • Hydrogen peroxide induces nuclear translocation of p53 and apoptosis in cells of oligodendroglia origin
    • Uberti, D., Yavin, E., Gil, S., Ayasola, K.R., Goldfinger, N., and Rotter, V. (1999). Hydrogen peroxide induces nuclear translocation of p53 and apoptosis in cells of oligodendroglia origin. Mol. Brain Res. 65, 167-175.
    • (1999) Mol. Brain Res. , vol.65 , pp. 167-175
    • Uberti, D.1    Yavin, E.2    Gil, S.3    Ayasola, K.R.4    Goldfinger, N.5    Rotter, V.6
  • 162
    • 0034822916 scopus 로고    scopus 로고
    • Brain and hippocampus fatty acid composition in phospholipid classes of aged-relative cognitive deficit rats
    • Ulmann, L., Mimouni, V., Roux, S., Porsolt, R., and Poisson, J.P. (2001). Brain and hippocampus fatty acid composition in phospholipid classes of aged-relative cognitive deficit rats. Prostaglandins Leukot. Essent. Fatty Acids 64, 189-195.
    • (2001) Prostaglandins Leukot. Essent. Fatty Acids , vol.64 , pp. 189-195
    • Ulmann, L.1    Mimouni, V.2    Roux, S.3    Porsolt, R.4    Poisson, J.P.5
  • 163
    • 0030969328 scopus 로고    scopus 로고
    • Oxidative injury of synapse and alteration of antioxidative defense systems in rats, and its prevention by vitamin E
    • Urano, S., Asai, Y., Makabe, S., Matsuo, M., Izumiyama, N., Ohtsubo, K., and Endo, T. (1997). Oxidative injury of synapse and alteration of antioxidative defense systems in rats, and its prevention by vitamin E. Eur. J. Biochem. 245, 64-70.
    • (1997) Eur. J. Biochem. , vol.245 , pp. 64-70
    • Urano, S.1    Asai, Y.2    Makabe, S.3    Matsuo, M.4    Izumiyama, N.5    Ohtsubo, K.6    Endo, T.7
  • 165
    • 84864346149 scopus 로고    scopus 로고
    • Elevated oxidative stress and decreased antioxidant function in the human hippocampus and frontal cortex with increasing age: Implications for neurodegeneration in Alzheimer's disease
    • Venkateshappa, C., Harish, G., Mahadevan, A., Bharath, M.S., and Shankar, S.K. (2012a). Elevated oxidative stress and decreased antioxidant function in the human hippocampus and frontal cortex with increasing age: Implications for neurodegeneration in Alzheimer's disease. Neurochem. Res. 37, 1601-1614.
    • (2012) Neurochem. Res. , vol.37 , pp. 1601-1614
    • Venkateshappa, C.1    Harish, G.2    Mahadevan, A.3    Bharath, M.S.4    Shankar, S.K.5
  • 166
    • 84856372105 scopus 로고    scopus 로고
    • Increased oxidative damage and decreased antioxidant function in aging human substantia nigra compared to striatum: Implications for Parkinson's disease
    • Venkateshappa, C., Harish, G., Mythri, R.B., Mahadevan, A., Bharath, M.S., and Shankar, S.K. (2012b). Increased oxidative damage and decreased antioxidant function in aging human substantia nigra compared to striatum: Implications for Parkinson's disease. Neurochem. Res. 37, 358-369.
    • (2012) Neurochem. Res. , vol.37 , pp. 358-369
    • Venkateshappa, C.1    Harish, G.2    Mythri, R.B.3    Mahadevan, A.4    Bharath, M.S.5    Shankar, S.K.6
  • 167
    • 0030200307 scopus 로고    scopus 로고
    • Antioxidant activities and mRNA expression of superoxide dismutase, catalase, and glutathione peroxidase in normal and preeclamptic placentas
    • Wang, Y. and Walsh, S.W. (1996). Antioxidant activities and mRNA expression of superoxide dismutase, catalase, and glutathione peroxidase in normal and preeclamptic placentas. J. Soc. Gynecol. Investig. 3, 179-184.
    • (1996) J. Soc. Gynecol. Investig. , vol.3 , pp. 179-184
    • Wang, Y.1    Walsh, S.W.2
  • 168
    • 0037010291 scopus 로고    scopus 로고
    • Age-related deficits in long-term potentiation are insensitive to hydrogen peroxide: Coincidence with enhanced autophosphorylation of Ca2+/calmodulin-dependent protein kinase II
    • Watson, J.B., Khorasani, H., Persson, A., Huang, K.P., Huang, F.L., and O'Dell, T.J. (2002). Age-related deficits in long-term potentiation are insensitive to hydrogen peroxide: Coincidence with enhanced autophosphorylation of Ca2+/calmodulin-dependent protein kinase II. J. Neurosci. Res. 70, 298-308.
    • (2002) J. Neurosci. Res. , vol.70 , pp. 298-308
    • Watson, J.B.1    Khorasani, H.2    Persson, A.3    Huang, K.P.4    Huang, F.L.5    O'Dell, T.J.6
  • 169
    • 33750604229 scopus 로고    scopus 로고
    • Agedependent modulation of hippocampal long-term potentiation by antioxidant enzymes
    • Watson, J.B., Arnold, M.M., Ho, Y.S., and O'Dell, T.J. (2006). Agedependent modulation of hippocampal long-term potentiation by antioxidant enzymes. J. Neurosci. Res. 84, 1564-1574.
    • (2006) J. Neurosci. Res. , vol.84 , pp. 1564-1574
    • Watson, J.B.1    Arnold, M.M.2    Ho, Y.S.3    O'Dell, T.J.4
  • 170
    • 0036790385 scopus 로고    scopus 로고
    • Oxidative stress, mitochondrial DNA mutation, and impairment of antioxidant enzymes in aging
    • Wei, Y.H. and Lee, H.C. (2002). Oxidative stress, mitochondrial DNA mutation, and impairment of antioxidant enzymes in aging. Exp. Biol. Med. 227, 671-682.
    • (2002) Exp. Biol. Med. , vol.227 , pp. 671-682
    • Wei, Y.H.1    Lee, H.C.2
  • 171
    • 0031465419 scopus 로고    scopus 로고
    • Antioxidant defense of the brain: A role for astrocytes
    • Wilson, J.X. (1997). Antioxidant defense of the brain: A role for astrocytes. Can. J. Physiol. Pharmacol. 75, 1149-1163.
    • (1997) Can. J. Physiol. Pharmacol. , vol.75 , pp. 1149-1163
    • Wilson, J.X.1
  • 172
    • 35748948033 scopus 로고    scopus 로고
    • A polymorphism in SOD2 is associated with development of Alzheimer's disease
    • Wiener, H. W., Perry, R. T., Chen, Z., Harrell, L. E., & Go, R. C. P. (2007). A polymorphism in SOD2 is associated with development of Alzheimer's disease. Genes, Brain and Behavior, 6, 770-776.
    • (2007) Genes, Brain and Behavior , vol.6 , pp. 770-776
    • Wiener, H.W.1    Perry, R.T.2    Chen, Z.3    Harrell, L.E.4    Go, R.C.P.5
  • 175
    • 0036752552 scopus 로고    scopus 로고
    • The role of polyunsaturated fatty acids in restoring the aging neuronal membrane
    • Yehuda, S., Rabinovitz, S., Carasso, R.L., and Mostofsky, D.I. (2002). The role of polyunsaturated fatty acids in restoring the aging neuronal membrane. Neurobiol. Aging 23, 843-853.
    • (2002) Neurobiol. Aging , vol.23 , pp. 843-853
    • Yehuda, S.1    Rabinovitz, S.2    Carasso, R.L.3    Mostofsky, D.I.4
  • 177
    • 0030886714 scopus 로고    scopus 로고
    • Sixteen-year longitudinal and time lag changes in memory and cognition in older adults
    • Zelinski, E.M. and Burnight, K.P. (1997). Sixteen-year longitudinal and time lag changes in memory and cognition in older adults. Psychol. Aging 12, 503.
    • (1997) Psychol. Aging , vol.12 , pp. 503
    • Zelinski, E.M.1    Burnight, K.P.2
  • 179
    • 3442885177 scopus 로고    scopus 로고
    • Association of polymorphic markers of the antioxidant enzyme genes with diabetic polyneuropathy in type 1 diabetes mellitus
    • Zotova, E.V., Savost'yanov, K.V., Chistyakov, D.A., Bursa, T.R., Galeev, I.V., Strokov, I.A., and Nosikov, V.V. (2004). Association of polymorphic markers of the antioxidant enzyme genes with diabetic polyneuropathy in type 1 diabetes mellitus. Mol. Biol. 38, 200-204.
    • (2004) Mol. Biol. , vol.38 , pp. 200-204
    • Zotova, E.V.1    Savost'yanov, K.V.2    Chistyakov, D.A.3    Bursa, T.R.4    Galeev, I.V.5    Strokov, I.A.6    Nosikov, V.V.7


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