Hydrogen peroxide induces rapid digestion of oligodendrocyte chromatin into high molecular weight fragments

Neurochemistry International

Volumn 38, Issue 1, 2001, Pages 9-15

  Mouzannar, R ^a   Miric, S J ^a   Wiggins, R C ^a   Konat, G W ^a  

^a WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Genomic damage; Higher order chromatin fragmentation; Oligodendrocytes; Oxidative stress; Programmed cell death

Indexed keywords

DNA FRAGMENT; HYDROGEN PEROXIDE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CHROMATIN; CONTROLLED STUDY; DNA DAMAGE; GENOME; MOLECULAR WEIGHT; NONHUMAN; OLIGODENDROGLIA; OXIDATIVE STRESS; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; CASPASES; CELLS, CULTURED; CHROMATIN; DNA FRAGMENTATION; DNA, SINGLE-STRANDED; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, AGAR GEL; ENDOPEPTIDASES; HYDROGEN PEROXIDE; KINETICS; MOLECULAR WEIGHT; NUCLEAR PROTEINS; OLIGODENDROGLIA; OXIDATIVE STRESS; RATS;

EID: 0035241613     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-0186(00)00066-8     Document Type: Article

References (32)

1. Beere H.M., Chresta C.M., Alejo-Herberg A., Skladanowski A., Dive C., Larsen A.K., Hickman J.A. Investigation of the mechanism of higher order chromatin fragmentation observed in drug-induced apoptosis. Molecular Pharmacology. 47:1995;986-996.
2. Bode J., Kohwi Y., Dickinson L., Joh T., Klehr D., Mielke C., Kohwi-Shigematsu T. Biological significance of unwinding capability of nuclear matrix-associated DNAs. Science. 255:1992;195-197.
3. Brown D.G., Sun X.M., Cohen G.M. Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation. Journal of Biological Chemistry. 268:1993;3037-3039.
4. Casciola-Rosen L., Nicholson D.W., Chang T., Rowan K.R., Thomberry N.A., Miller D.K., Rosen A. Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death. Journal of Experimental Medicine. 183:1996;1957-1964.
5. Chinnayian A.M., Tepper C.G., Seldin M.F., O'Rourke K., Kischkel F.C., Helbard S., Krammer P.H., Peter M.E., Dixit V.M. FADD/MORT1 is a common mediator of CD95 (Fas/APO1) and tumor necrosis factor receptor-induced apoptosis. Journal of Biological Chemistry. 271:1996;4961-4965.
6. Cohen G.M., Sun X.M., Fearnhea H., MacFarlane M., Brown D.G., Snowden R.T., Dinsdale D. Formation of large molecular weight fragments of DNA is a key committed step of apoptosis in thymocytes. Journal of Immunology. 153:1994;507-516.
7. Dickinson L.A., Joh T., Kohwi Y., Kohwi-Shigematsu T. A tissue-specific MAR/SAR DNA-binding protein with unusual binding site recognition. Cell. 70:1992;631-645.
8. Greidinger E.L., Miller D.K., Yamin T.T., Casciola-Rosen L., Rosen A. Sequential activation of three distinct ICE-like activities in Fas-ligated Jurkat cells. FEBS Letters. 390:1996;299-303.
9. Grubinska B., Laszkiewicz I., Royland J.E., Wiggins R.C., Konat G.W. Differentiation-specific demethylation of myelin associated glycoprotein gene in cultured oligodendrocytes. Journal of Neuroscience Research. 39:1994;233-242.
10. Gu J., Royland J.E., Wiggins R.C., Konat G.W. Selenium is required for normal upregulation of myelin genes in differentiating oligodendrocytes. Journal of Neuroscience Research. 47:1997;626-635.
11. Hendzel M.J., Nishioka K., Raymond Y., Allis C.D., Bazett-Jones D.P., Th'ng P.H. Chromatin condensation is not associated with apoptosis. Journal of Biological Chemistry. 273:1998;24470-24478.
12. 2 in vitro. Brain Research. 671:1995;181-186.
13. Lagarkova M.A., Iarovaia O.V., Razin S.V. Large scale fragmentation of mammalian DNA in the course of apoptosis procedes via excision of chromosomal DNA loops and their oligomers. Journal of Biological Chemistry. 270:1995;20239-20245.
14. Laszkiewicz I., Mouzannar R., Wiggins R.C., Konat G.W. Delayed oligodendrocyte degeneration induced by brief exposure to hydrogen peroxide. Journal of Neuroscience Research. 55:1999;303-310.
15. Liu Q.Y., Padney S., Singh R.K., Lin W., Ribecco M., Borowy-Borowski H., Smith B., LeBlanc J., Walker P.R., Sikorska M. DNaseY: A rat DNase-like gene coding for a constitutively expressed chromatin-bound endonuclease. Biochemistry. 37:1998;10134-10143.
16. Mouzannar R., Laszkiewicz I., Wiggins R.C., Konat G.W. Chromatin fregmentation in oxidatively stressed oligodendrocytes. Journal of Neurochemistry. 72:1999;S6D.
17. Oberhammer F., Fritsch G., Schmeid M., Pavelka M., Printz D., Purchio T., Lassmann H., Schulte-Hermann R. Condensation of the chromatin at the membrane of an apoptotic nucleus is not associated with activation of activation of an endonuclease. Journal of Cell Science. 104:1993;317-326.
18. Oberhammer F., Wilson J.W., Dive C., Morris I.D., Hickman J.A., Wakeling A.E., Walker P.R., Sikorska M. Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation. EMBO Journal. 12:1993;3679-3684.
19. Pandey S., Walker P.R., Sikorska M. Separate pools of endonuclease activity are responsible for internucleosomal and high molecular mass DNA fragmentation during apoptosis. Biochemistry and Cell Biology. 72:1994;625-629.
20. Pantoni L., Garcia J.H., Gutierrez J.A. Cerebral white matter is highly vulnerable to ischemia. Stroke. 27:1996;1641-1646.
21. Peitch M.C., Muller C., Tschopp J. DNA fragmentation during apoptosis is caused by single-strand cuts. Nucleic Acid Research. 21:1993;4206-4209.
22. Petito C.K., Orlate J.P., Roberts B., Nowak T.S., Pulsinelli W.A. Selective glial vulnerability following transient global ischemia in rat brain. Journal of Neuropathology and Experimental Neurology. 57:1998;231-238.
23. Scott G.S., Williams K.I., Bolton C. Reactive oxygen species in experimental allergic encephalomyelitis. Biochemical Society Transactions. 25:1997;166S.
24. Sikorska M., Walker P.R. Endonuclease activities and apoptosis. Lockshin R.A., Zakeri Z., Tilly J.L. When Cells Die. A Comprehensive Evaluation of Apoptosis and Programmed Cell Death. 1998;211-242 Wiley-Liss, New York, Chichester, Weinheim, Brisbane, Singapore, Toronto.
25. 2+-dependent cleavage of DNA into kilobase pair fragments is responsible for the initial degradation of DNA in apoptosis. Journal of Biological Chemistry. 269:1994;14857-14860.
26. Sun X.M., Snowden R.T., Dinsdale D., Ormerod M.G., Cohen G.M. Changes in nuclear chromatin precede internucleosomal DNA cleavage in the induction of apoptosis by etoposide. Biochemical Pharmacology. 2:1993;187-195.
27. Walker P.R., LeBlanc J., Carson C., Sikorska M. Neither caspase-3 nor DNA fragmentation factor are required for high molecular weight DNA degradation in apoptosis. Annals of New York Academy of Sciences. 887:2000;48-60.
28. Walker P.R., LeBlanc J., Sikorska M. Evidence that DNA fragmentation in apoptosis is initiated and propagated by single-strand breaks. Cell Death and Differentiation. 4:1997;506-515.
29. Walker P.R., Pandey S., Sikorska M. Degradation of chromatin in apoptotic cells. Cell Death and Differentiation. 2:1995;97-104.
30. Walker P.R., Sikorska M. New aspects of the mechanisms of DNA fragmentation in apoptosis. Biochemistry and Cell Biology. 75:1997;287-299.
31. Weaver V.M., Carson C.E., Walker P.R., Chaly N., Lach B., Raymond Y., Sikorska M. Degradation of nuclear matrix and DNA cleavage in apoptotic thymocytes. Journal of Cell Science. 109:1996;45-56.
32. Zhivotovsky B., Cederall B., Jiang S., Nicotera P., Orrenius S. Involvement of Ca2+ in the formation of high molecular weight DNA fragments in thymocyte apoptosis. Biochemical and Biophysical Research Communications. 202:1994;120-127.