-
1
-
-
0036829433
-
Rate of generation of oxidative stress-related damage and animal longevity
-
Barja G. Rate of generation of oxidative stress-related damage and animal longevity. Free Radic. Biol. Med. 33 (2002) 1167-1172
-
(2002)
Free Radic. Biol. Med.
, vol.33
, pp. 1167-1172
-
-
Barja, G.1
-
2
-
-
27444442915
-
Enhanced catabolism of mitochondrial superoxide/hydrogen peroxide and aging in transgenic
-
Bayne V.A., Mockett R.J., Orr W.C., and Sohal R.S. Enhanced catabolism of mitochondrial superoxide/hydrogen peroxide and aging in transgenic. Drosophila Biochem. J. 391 (2005) 277-284
-
(2005)
Drosophila Biochem. J.
, vol.391
, pp. 277-284
-
-
Bayne, V.A.1
Mockett, R.J.2
Orr, W.C.3
Sohal, R.S.4
-
3
-
-
3142686745
-
The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes
-
Bellen H.J., Levis R.W., Liao G., He Y., Carlson J.W., Tsang G., Evans-Holm M., Hiesinger P.R., Schulze K.L., Rubin G.M., Hoskins R.A., and Spradling A.C. The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. Genetics 167 (2004) 761-781
-
(2004)
Genetics
, vol.167
, pp. 761-781
-
-
Bellen, H.J.1
Levis, R.W.2
Liao, G.3
He, Y.4
Carlson, J.W.5
Tsang, G.6
Evans-Holm, M.7
Hiesinger, P.R.8
Schulze, K.L.9
Rubin, G.M.10
Hoskins, R.A.11
Spradling, A.C.12
-
4
-
-
0037799688
-
Dissociation between functional senescence and oxidative stress resistance in Drosophila
-
Cook-Wiens E., and Grotewiel M.S. Dissociation between functional senescence and oxidative stress resistance in Drosophila. Exp. Gerontol. 37 (2002) 1347-1357
-
(2002)
Exp. Gerontol.
, vol.37
, pp. 1347-1357
-
-
Cook-Wiens, E.1
Grotewiel, M.S.2
-
5
-
-
0035890871
-
Selectivity of protein oxidative damage during aging in Drosophila melanogaster
-
Das N., Levine R.L., Orr W.C., and Sohal R.S. Selectivity of protein oxidative damage during aging in Drosophila melanogaster. Biochem. J. 360 (2001) 209-216
-
(2001)
Biochem. J.
, vol.360
, pp. 209-216
-
-
Das, N.1
Levine, R.L.2
Orr, W.C.3
Sohal, R.S.4
-
7
-
-
0346100684
-
A Sod2 null mutation confers severely reduced adult life span in Drosophila
-
Duttaroy A., Paul A., Kundu M., and Belton A. A Sod2 null mutation confers severely reduced adult life span in Drosophila. Genetics 165 (2003) 2295-2299
-
(2003)
Genetics
, vol.165
, pp. 2295-2299
-
-
Duttaroy, A.1
Paul, A.2
Kundu, M.3
Belton, A.4
-
8
-
-
33646922865
-
Reduction in mitochondrial superoxide dismutase modulates Alzheimer's disease-like pathology and accelerates the onset of behavioral changes in human amyloid precursor protein transgenic mice
-
Esposito L., Raber J., Kekonius L., Yan F., Yu G.Q., Bien-Ly N., Puolivali J., Scearce-Levie K., Masliah E., and Mucke L. Reduction in mitochondrial superoxide dismutase modulates Alzheimer's disease-like pathology and accelerates the onset of behavioral changes in human amyloid precursor protein transgenic mice. J. Neurosci. 26 (2006) 5167-5179
-
(2006)
J. Neurosci.
, vol.26
, pp. 5167-5179
-
-
Esposito, L.1
Raber, J.2
Kekonius, L.3
Yan, F.4
Yu, G.Q.5
Bien-Ly, N.6
Puolivali, J.7
Scearce-Levie, K.8
Masliah, E.9
Mucke, L.10
-
9
-
-
0034733807
-
Redox-dependent signal transduction
-
Finkel T. Redox-dependent signal transduction. FEBS Lett. 476 (2000) 52-54
-
(2000)
FEBS Lett.
, vol.476
, pp. 52-54
-
-
Finkel, T.1
-
10
-
-
34248580935
-
Alteration of Drosophila life span using conditional, tissue-specific expression of transgenes triggered by doxycyline or RU486/Mifepristone
-
Ford D., Hoe N., Landis G., Tozer K., Luu A., Bhole D., Badrinath A., and Tower J. Alteration of Drosophila life span using conditional, tissue-specific expression of transgenes triggered by doxycyline or RU486/Mifepristone. Exp. Gerontol. 42 (2007) 483-497
-
(2007)
Exp. Gerontol.
, vol.42
, pp. 483-497
-
-
Ford, D.1
Hoe, N.2
Landis, G.3
Tozer, K.4
Luu, A.5
Bhole, D.6
Badrinath, A.7
Tower, J.8
-
11
-
-
0026045587
-
Superoxide sensitivity of the Escherichia coli aconitase
-
Fridovich I., and Gardner P.R. Superoxide sensitivity of the Escherichia coli aconitase. J. Biol. Chem. 266 (1991) 19328-193233
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 19328-193233
-
-
Fridovich, I.1
Gardner, P.R.2
-
12
-
-
0028075773
-
Aconitase is a sensitive and critical target of oxygen poisioning in cultured mammalian cells and in rat lungs
-
Gardner P.R., Nguyen D.D., and White C.W. Aconitase is a sensitive and critical target of oxygen poisioning in cultured mammalian cells and in rat lungs. Proc. Natl. Acad. Sci. U.S.A. 91 (1994) 12248-12252
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 12248-12252
-
-
Gardner, P.R.1
Nguyen, D.D.2
White, C.W.3
-
13
-
-
0035710229
-
An overview of real-time quantitative PCR: applications to quantify cytokine gene expression
-
Giulietti A., Overburgh L., Valckx D., Decallonne B., Bouillon R., and Mathieu C. An overview of real-time quantitative PCR: applications to quantify cytokine gene expression. Methods 25 (2001) 386-401
-
(2001)
Methods
, vol.25
, pp. 386-401
-
-
Giulietti, A.1
Overburgh, L.2
Valckx, D.3
Decallonne, B.4
Bouillon, R.5
Mathieu, C.6
-
14
-
-
0003293418
-
On the nature of the function expressive of the law of human mortality and on a new mode of determining life contingencies
-
Gompertz B. On the nature of the function expressive of the law of human mortality and on a new mode of determining life contingencies. Philos. Trans. R. Soc. Lond. 115 (1825) 513-585
-
(1825)
Philos. Trans. R. Soc. Lond.
, vol.115
, pp. 513-585
-
-
Gompertz, B.1
-
16
-
-
33746344025
-
ROS as signalling molecules in T cells-evidence for abnormal redox signaling in the autoimmune disease, rheumatoid arthritis
-
Griffiths H.R. ROS as signalling molecules in T cells-evidence for abnormal redox signaling in the autoimmune disease, rheumatoid arthritis. Redox Rep. 10 (2005) 273-280
-
(2005)
Redox Rep.
, vol.10
, pp. 273-280
-
-
Griffiths, H.R.1
-
18
-
-
77049308856
-
Aging: a theory based on free radical and radiation chemistry
-
Harman D. Aging: a theory based on free radical and radiation chemistry. J. Gerontol. 11 (1956) 298-300
-
(1956)
J. Gerontol.
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
19
-
-
0015319592
-
The biologic clock: the mitochondria?
-
Harman D. The biologic clock: the mitochondria?. J. Am. Geriatr. Soc. 20 (1972) 145-147
-
(1972)
J. Am. Geriatr. Soc.
, vol.20
, pp. 145-147
-
-
Harman, D.1
-
20
-
-
33744478401
-
Free radical theory of aging: an update: increasing the functional life span
-
Harman D. Free radical theory of aging: an update: increasing the functional life span. Ann. NY Acad. Sci. (United States) 1067 (2006) 10-21
-
(2006)
Ann. NY Acad. Sci. (United States)
, vol.1067
, pp. 10-21
-
-
Harman, D.1
-
21
-
-
0037470539
-
Genetics and the specificity of the aging process
-
Hekimi S., and Guarente L. Genetics and the specificity of the aging process. Science 299 (2003) 1351-1354
-
(2003)
Science
, vol.299
, pp. 1351-1354
-
-
Hekimi, S.1
Guarente, L.2
-
22
-
-
0014198972
-
Purification and kinetic studies of beef liver cytoplasmic aconitase
-
Henson C.P., and Cleland W.W. Purification and kinetic studies of beef liver cytoplasmic aconitase. J. Biol. Chem. 242 (1967) 3833-3838
-
(1967)
J. Biol. Chem.
, vol.242
, pp. 3833-3838
-
-
Henson, C.P.1
Cleland, W.W.2
-
23
-
-
0942298545
-
Endogenous mitochondrial oxidative stress: neurodegeneration, proteomic analysis, specific respiratory chain defects, and efficacious antioxidant therapy in superoxide dismutase 2 null mice
-
Hinerfeld D., Traini M.D., Weinberger R.P., Cochran B., Doctrow S.R., Harry J., and Melov S. Endogenous mitochondrial oxidative stress: neurodegeneration, proteomic analysis, specific respiratory chain defects, and efficacious antioxidant therapy in superoxide dismutase 2 null mice. J. Neurochem. 88 (2004) 657-667
-
(2004)
J. Neurochem.
, vol.88
, pp. 657-667
-
-
Hinerfeld, D.1
Traini, M.D.2
Weinberger, R.P.3
Cochran, B.4
Doctrow, S.R.5
Harry, J.6
Melov, S.7
-
24
-
-
33846345418
-
Hippocampul long term potentiation, memory and longevity in mice that overexpress mitochondrial superoxide dismutase
-
Hu D., Cao P., Edda T., Chu C.T., Wu G.-Y., Oury D.T., and Klann E. Hippocampul long term potentiation, memory and longevity in mice that overexpress mitochondrial superoxide dismutase. Neurobiol. Learn. Mem. 87 (2007) 372-384
-
(2007)
Neurobiol. Learn. Mem.
, vol.87
, pp. 372-384
-
-
Hu, D.1
Cao, P.2
Edda, T.3
Chu, C.T.4
Wu, G.-Y.5
Oury, D.T.6
Klann, E.7
-
25
-
-
33645128441
-
Genetic modifiers of the phenotype of mice deficient in mitochondrial superoxide dismutase
-
Huang T.T., Naeemuddin M., Elchuri S., Yamaguchi M., Kozy H.M., Carlson E.J., and Epstein C.J. Genetic modifiers of the phenotype of mice deficient in mitochondrial superoxide dismutase. Hum. Mol. Genet. 15 (2006) 1187-1194
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 1187-1194
-
-
Huang, T.T.1
Naeemuddin, M.2
Elchuri, S.3
Yamaguchi, M.4
Kozy, H.M.5
Carlson, E.J.6
Epstein, C.J.7
-
26
-
-
0033886373
-
Oxidant signaling in vascular cell growth, death, and survival: a review of the roles of reactive oxygen species in smooth muscle and endothelial cell mitogenic and apoptotic signaling
-
Irani K. Oxidant signaling in vascular cell growth, death, and survival: a review of the roles of reactive oxygen species in smooth muscle and endothelial cell mitogenic and apoptotic signaling. Circ. Res. 87 (2000) 179-183
-
(2000)
Circ. Res.
, vol.87
, pp. 179-183
-
-
Irani, K.1
-
27
-
-
2942555103
-
Superoxide dismutase mimetics elevate superoxide dismutase activity in vivo but do not retard aging in the nematode Caenorhabditis elegans
-
Keaney M., Matthijssens F., Sharpe M., et al. Superoxide dismutase mimetics elevate superoxide dismutase activity in vivo but do not retard aging in the nematode Caenorhabditis elegans. Free Radic. Biol. Med. 37 (2004) 239-250
-
(2004)
Free Radic. Biol. Med.
, vol.37
, pp. 239-250
-
-
Keaney, M.1
Matthijssens, F.2
Sharpe, M.3
-
28
-
-
0037059057
-
RNA interference-mediated silencing of Sod2 in Drosophila leads to early adult-onset mortality and elevated endogenous oxidative stress
-
Kirby K., Hu J., Hilliker A.J., and Phillips J.P. RNA interference-mediated silencing of Sod2 in Drosophila leads to early adult-onset mortality and elevated endogenous oxidative stress. Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 16162-16167
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 16162-16167
-
-
Kirby, K.1
Hu, J.2
Hilliker, A.J.3
Phillips, J.P.4
-
29
-
-
0035956929
-
Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age related decli. ne of mitochondrial function culminating in increased apoptosis
-
Kokoszka J.E., Coskun P., Esposito L.A., and Wallace D.C. Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age related decli. ne of mitochondrial function culminating in increased apoptosis. Proc. Natl. Acad. Sci. USA 98 (2001) 2278-2283
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 2278-2283
-
-
Kokoszka, J.E.1
Coskun, P.2
Esposito, L.A.3
Wallace, D.C.4
-
30
-
-
0036085278
-
Lifespan does not measure ageing
-
Kowald A. Lifespan does not measure ageing. Biogerontology 3 (2002) 187-190
-
(2002)
Biogerontology
, vol.3
, pp. 187-190
-
-
Kowald, A.1
-
31
-
-
12344276944
-
Superoxide dismutase evolution and life span regulation
-
Landis G.N., and Tower J. Superoxide dismutase evolution and life span regulation. Mech. Ageing Dev. 126 (2005) 365-379
-
(2005)
Mech. Ageing Dev.
, vol.126
, pp. 365-379
-
-
Landis, G.N.1
Tower, J.2
-
32
-
-
0029838063
-
Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice
-
Lebovitz R.M., Zhang H., Vogel H., Cartwright Jr. J., Dionne L., Lu N., Huang S., and Matzuk M.M. Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice. Proc. Natl. Acad. Sci. U.S.A. 93 (1996) 9782-9787
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 9782-9787
-
-
Lebovitz, R.M.1
Zhang, H.2
Vogel, H.3
Cartwright Jr., J.4
Dionne, L.5
Lu, N.6
Huang, S.7
Matzuk, M.M.8
-
33
-
-
33646934067
-
A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span
-
Lehtinen M.K., Yuan Z., Boag P.R., Yang Y., Villen J., Becker E.B., DiBacco S., de la Iglesia N., Gygi S., Blackwell T.K., and Bonni A. A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span. Cell 125 (2006) 987-1001
-
(2006)
Cell
, vol.125
, pp. 987-1001
-
-
Lehtinen, M.K.1
Yuan, Z.2
Boag, P.R.3
Yang, Y.4
Villen, J.5
Becker, E.B.6
DiBacco, S.7
de la Iglesia, N.8
Gygi, S.9
Blackwell, T.K.10
Bonni, A.11
-
34
-
-
0028827252
-
Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
-
Li Y., Huang T.T., Carlson E.J., Melov S., Ursell P.C., Olson J.L., Noble L.J., Yoshimura M.P., Berger C., Chan P.H., et al. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nat. Genet. 11 (1995) 376-381
-
(1995)
Nat. Genet.
, vol.11
, pp. 376-381
-
-
Li, Y.1
Huang, T.T.2
Carlson, E.J.3
Melov, S.4
Ursell, P.C.5
Olson, J.L.6
Noble, L.J.7
Yoshimura, M.P.8
Berger, C.9
Chan, P.H.10
-
36
-
-
0037470488
-
Evolutionary medicine: from dwarf model systems to healthy centenarians?
-
Longo V.D., and Finch C.E. Evolutionary medicine: from dwarf model systems to healthy centenarians?. Science 299 (2003) 1342-1346
-
(2003)
Science
, vol.299
, pp. 1342-1346
-
-
Longo, V.D.1
Finch, C.E.2
-
37
-
-
13844253808
-
Selective neuronal vulnerability and inadequate stress response in superoxide dismutase mutant mice
-
Lynn S., Huang E.J., Elchuri S., Naeemuddin M., Nishinaka Y., Yodoi J., Ferriero D.M., Epstein C.J., and Huang T.T. Selective neuronal vulnerability and inadequate stress response in superoxide dismutase mutant mice. Free Radic. Biol. Med. 38 (2005) 817-828
-
(2005)
Free Radic. Biol. Med.
, vol.38
, pp. 817-828
-
-
Lynn, S.1
Huang, E.J.2
Elchuri, S.3
Naeemuddin, M.4
Nishinaka, Y.5
Yodoi, J.6
Ferriero, D.M.7
Epstein, C.J.8
Huang, T.T.9
-
38
-
-
18044363639
-
oxidative stress and human pathologies: a brief history and a future vision
-
McCord J.M., and Edeas M.A.S.O.D. oxidative stress and human pathologies: a brief history and a future vision. Biomed. Pharmacother. 59 (2005) 139-142
-
(2005)
Biomed. Pharmacother.
, vol.59
, pp. 139-142
-
-
McCord, J.M.1
Edeas, M.A.S.O.D.2
-
39
-
-
0031940986
-
A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase
-
Melov S., Schneider J.A., Day B.J., Hinerfeld D., Coskun P., Mirra S.S., Crapo J.D., and Wallace D.C. A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase. Nat. Genet. 18 (1998) 159-163
-
(1998)
Nat. Genet.
, vol.18
, pp. 159-163
-
-
Melov, S.1
Schneider, J.A.2
Day, B.J.3
Hinerfeld, D.4
Coskun, P.5
Mirra, S.S.6
Crapo, J.D.7
Wallace, D.C.8
-
40
-
-
13044285432
-
Mitochondrial disease in superoxide dismutase 2 mutant mice
-
Melov S., Coskun P., Patel M., Tuinstra R., Cottrell B., Jun A.S., Zastawny T.H., Dizdaroglu M., Goodman S.I., Huang T.T., Miziorko H., Epstein C.J., and Wallace D.C. Mitochondrial disease in superoxide dismutase 2 mutant mice. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 551-846
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 551-846
-
-
Melov, S.1
Coskun, P.2
Patel, M.3
Tuinstra, R.4
Cottrell, B.5
Jun, A.S.6
Zastawny, T.H.7
Dizdaroglu, M.8
Goodman, S.I.9
Huang, T.T.10
Miziorko, H.11
Epstein, C.J.12
Wallace, D.C.13
-
41
-
-
0035503501
-
Lifespan extension and rescue of spongiform encephalopathy in superoxide dismutase 2 nullizygous mice treated with superoxide dismutase-catalase mimetics
-
Melov S., Doctrow S.R., Schneider J.A., Haberson J., Patel M., Coskun P.E., Huffman K., Wallace D.C., and Malfroy B. Lifespan extension and rescue of spongiform encephalopathy in superoxide dismutase 2 nullizygous mice treated with superoxide dismutase-catalase mimetics. J. Neurosci. 21 (2001) 8348-8353
-
(2001)
J. Neurosci.
, vol.21
, pp. 8348-8353
-
-
Melov, S.1
Doctrow, S.R.2
Schneider, J.A.3
Haberson, J.4
Patel, M.5
Coskun, P.E.6
Huffman, K.7
Wallace, D.C.8
Malfroy, B.9
-
42
-
-
0033571777
-
Overexpression of Mn-containing superoxide dismutase in transgenic Drosophila melanogaster
-
Mockett R.J., Orr W.C., Rahmandar J.J., Benes J.J., Radyuk S.N., Klichko V.I., and Sohal R.S. Overexpression of Mn-containing superoxide dismutase in transgenic Drosophila melanogaster. Arch. Biochem. Biophys. 371 (1999) 260-269
-
(1999)
Arch. Biochem. Biophys.
, vol.371
, pp. 260-269
-
-
Mockett, R.J.1
Orr, W.C.2
Rahmandar, J.J.3
Benes, J.J.4
Radyuk, S.N.5
Klichko, V.I.6
Sohal, R.S.7
-
43
-
-
34447316414
-
Trends in oxidative aging theories
-
Muller F.L., Lustgarten M.S., Jang Y., Richardson A., and Van Remmen H. Trends in oxidative aging theories. Free Radic. Biol. Med. 43 (2007) 477-503
-
(2007)
Free Radic. Biol. Med.
, vol.43
, pp. 477-503
-
-
Muller, F.L.1
Lustgarten, M.S.2
Jang, Y.3
Richardson, A.4
Van Remmen, H.5
-
44
-
-
0042092531
-
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
-
Murphy C.T., McCarroll S.A., Bargmann C.I., Fraser A., Kamath R.S., Ahringer J., Li H., and Kenyon C. Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 424 (2003) 277-283
-
(2003)
Nature
, vol.424
, pp. 277-283
-
-
Murphy, C.T.1
McCarroll, S.A.2
Bargmann, C.I.3
Fraser, A.4
Kamath, R.S.5
Ahringer, J.6
Li, H.7
Kenyon, C.8
-
45
-
-
0028280787
-
The toxicity of high-dose superoxide dismutase suggests that superoxide can both initiate and terminate lipid peroxidation in the reperfused heart
-
Nelson S.K., Bose S.K., and McCord J.M. The toxicity of high-dose superoxide dismutase suggests that superoxide can both initiate and terminate lipid peroxidation in the reperfused heart. Free Radic. Biol. Med. 16 (1994) 195-200
-
(1994)
Free Radic. Biol. Med.
, vol.16
, pp. 195-200
-
-
Nelson, S.K.1
Bose, S.K.2
McCord, J.M.3
-
46
-
-
0038712734
-
Effects of overexpression of copper-zinc and manganese superoxide dismutases, catalase, and thioredoxin reductase genes on longevity in Drosophila melanogaster
-
Orr W.C., Mockett R.J., Benes J.J., and Sohal R.S. Effects of overexpression of copper-zinc and manganese superoxide dismutases, catalase, and thioredoxin reductase genes on longevity in Drosophila melanogaster. J. Biol. Chem. 278 (2003) 26418-26422
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 26418-26422
-
-
Orr, W.C.1
Mockett, R.J.2
Benes, J.J.3
Sohal, R.S.4
-
47
-
-
0032966938
-
Model fitting and hypothesis testing for age-specific mortality data
-
Pletcher S.D. Model fitting and hypothesis testing for age-specific mortality data. J. Evol. Biol. 12 (1999) 430-439
-
(1999)
J. Evol. Biol.
, vol.12
, pp. 430-439
-
-
Pletcher, S.D.1
-
48
-
-
0034535162
-
Why do life spans differ? Partitioning mean longevity differences in terms of age-specific mortality parameters
-
Pletcher S.D., Khazaeli A.A., and Curtsinger J.W. Why do life spans differ? Partitioning mean longevity differences in terms of age-specific mortality parameters. J. Gerontol. A: Biol. Sci. Med. Sci. 55 (2000) B381-B389
-
(2000)
J. Gerontol. A: Biol. Sci. Med. Sci.
, vol.55
-
-
Pletcher, S.D.1
Khazaeli, A.A.2
Curtsinger, J.W.3
-
49
-
-
0000342177
-
Spectrophotometric measurements of the enzymatic formation of fumaric and cis-aconitic acids
-
Racker E. Spectrophotometric measurements of the enzymatic formation of fumaric and cis-aconitic acids. Biochim. Biophys. Acta 4 (1950) 211-214
-
(1950)
Biochim. Biophys. Acta
, vol.4
, pp. 211-214
-
-
Racker, E.1
-
50
-
-
21144434217
-
Extension of murine life span by overexpression of catalase targeted to mitochondria
-
Schriner S.E., Linford N.J., Martin G.M., Treuting P., Ogburn C.E., Emond M., Coskun P.E., Ladiges W., Wolf N., Van Remmen H., Wallace D.C., and Rabinovitch P.S. Extension of murine life span by overexpression of catalase targeted to mitochondria. Science 24 308 (5730) (2005) 1909-1911
-
(2005)
Science
, vol.24
, Issue.308 5730
, pp. 1909-1911
-
-
Schriner, S.E.1
Linford, N.J.2
Martin, G.M.3
Treuting, P.4
Ogburn, C.E.5
Emond, M.6
Coskun, P.E.7
Ladiges, W.8
Wolf, N.9
Van Remmen, H.10
Wallace, D.C.11
Rabinovitch, P.S.12
-
51
-
-
28644442428
-
SOD2 overexpression: enhanced mitochondrial tolerance but absence of effect on UCP activity
-
Silva J.P., Shabalina I.G., Dufour E., Petrovic N., Backlund E.C., Hultenby K., Wibom1 R., Nedergaard J., Cannon B., and Larsson N.-G. SOD2 overexpression: enhanced mitochondrial tolerance but absence of effect on UCP activity. EMBO J. 24 (2005) 4061-4070
-
(2005)
EMBO J.
, vol.24
, pp. 4061-4070
-
-
Silva, J.P.1
Shabalina, I.G.2
Dufour, E.3
Petrovic, N.4
Backlund, E.C.5
Hultenby, K.6
Wibom1, R.7
Nedergaard, J.8
Cannon, B.9
Larsson, N.-G.10
-
52
-
-
0036709816
-
Oxidative stress hypothesis of aging
-
Sohal R.S. Oxidative stress hypothesis of aging. Free Radic. Biol. Med. 33 (2002) 573-574
-
(2002)
Free Radic. Biol. Med.
, vol.33
, pp. 573-574
-
-
Sohal, R.S.1
-
53
-
-
0028268734
-
Mitochondrial oxidative damage, hydrogen peroxide release, and aging
-
Sohal R.S., and Dubey A. Mitochondrial oxidative damage, hydrogen peroxide release, and aging. Free Radic. Biol. Med. 16 (1994) 621-626
-
(1994)
Free Radic. Biol. Med.
, vol.16
, pp. 621-626
-
-
Sohal, R.S.1
Dubey, A.2
-
54
-
-
0026023219
-
Hydrogen peroxide release by mitochondria increases during aging
-
Sohal R.S., and Sohal B.H. Hydrogen peroxide release by mitochondria increases during aging. Mech. Ageing Dev. 57 (1991) 187-202
-
(1991)
Mech. Ageing Dev.
, vol.57
, pp. 187-202
-
-
Sohal, R.S.1
Sohal, B.H.2
-
55
-
-
0030038103
-
Oxidative stress, caloric restriction, and aging
-
Sohal R.S., and Weindruch R. Oxidative stress, caloric restriction, and aging. Science 273 (1996) 59-63
-
(1996)
Science
, vol.273
, pp. 59-63
-
-
Sohal, R.S.1
Weindruch, R.2
-
56
-
-
0036710886
-
Mechanisms of aging: an appraisal of the oxidative stress hypothesis
-
Sohal R.S., Mockett R.J., and Orr W.C. Mechanisms of aging: an appraisal of the oxidative stress hypothesis. Free Radic. Biol. Med. 33 (2002) 575-586
-
(2002)
Free Radic. Biol. Med.
, vol.33
, pp. 575-586
-
-
Sohal, R.S.1
Mockett, R.J.2
Orr, W.C.3
-
58
-
-
0035989388
-
Induced overexpression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophila melanogaster
-
Sun J., Folk D., Bradley T.J., and Tower J. Induced overexpression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophila melanogaster. Genetics 161 (2002) 661-672
-
(2002)
Genetics
, vol.161
, pp. 661-672
-
-
Sun, J.1
Folk, D.2
Bradley, T.J.3
Tower, J.4
-
59
-
-
2342548187
-
Effects of simultaneous over-expression of Cu/ZnSOD and MnSOD on Drosophila melanogaster life span
-
Sun J., Molitor J., and Tower J. Effects of simultaneous over-expression of Cu/ZnSOD and MnSOD on Drosophila melanogaster life span. Mech. Aging Dev. 125 2004 (2004) 341-349
-
(2004)
Mech. Aging Dev.
, vol.125
, Issue.2004
, pp. 341-349
-
-
Sun, J.1
Molitor, J.2
Tower, J.3
-
60
-
-
0037470501
-
The endocrine regulation of aging by insulin-like signals
-
Tatar M., Bartke A., and Antebi A. The endocrine regulation of aging by insulin-like signals. Science 299 (2003) 1346-1351
-
(2003)
Science
, vol.299
, pp. 1346-1351
-
-
Tatar, M.1
Bartke, A.2
Antebi, A.3
-
61
-
-
0033102629
-
Characterization of the antioxidant status of the heterozygous manganese superoxide dismutase knockout mouse
-
Van Remmen H., Salvador C., Yang H., Huang T.T., Epstein C.J., and Richardson A. Characterization of the antioxidant status of the heterozygous manganese superoxide dismutase knockout mouse. Arch. Biochem. Biophys. 363 1 (1999) 91-97
-
(1999)
Arch. Biochem. Biophys.
, vol.363
, Issue.1
, pp. 91-97
-
-
Van Remmen, H.1
Salvador, C.2
Yang, H.3
Huang, T.T.4
Epstein, C.J.5
Richardson, A.6
-
62
-
-
0034838078
-
Knockout mice heterozygous for Sod2 show alterations in cardiac mitochondrial function and apoptosis
-
Van Remmen H., Williams M.D., Guo Z., Estlack L., Yang H., Carlson E.J., Epstein C.J., Huang T.T., and Richardson A. Knockout mice heterozygous for Sod2 show alterations in cardiac mitochondrial function and apoptosis. Am. J. Physiol. Heart Circ. Physiol. 281 (2001) H1422-H1432
-
(2001)
Am. J. Physiol. Heart Circ. Physiol.
, vol.281
-
-
Van Remmen, H.1
Williams, M.D.2
Guo, Z.3
Estlack, L.4
Yang, H.5
Carlson, E.J.6
Epstein, C.J.7
Huang, T.T.8
Richardson, A.9
-
63
-
-
12144288373
-
Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging
-
Van Remmen H., Ikeno Y., Hamilton M., et al. Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging. Physiol. Genomics 16 (2004) 29-37
-
(2004)
Physiol. Genomics
, vol.16
, pp. 29-37
-
-
Van Remmen, H.1
Ikeno, Y.2
Hamilton, M.3
-
64
-
-
0032561328
-
Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superocide dismutase knock out mice
-
Williams M.D., Van Remmen H., Conrad C.C., Huang T.T., Epstein C.J., and Richardson A. Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superocide dismutase knock out mice. J. Biol. Chem. 273 (1998) 28415-28510
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 28415-28510
-
-
Williams, M.D.1
Van Remmen, H.2
Conrad, C.C.3
Huang, T.T.4
Epstein, C.J.5
Richardson, A.6
-
65
-
-
33645788618
-
Pol II-expressed shRNA knocks down Sod2 gene expression and causes phenotypes of the gene knockout in mice
-
Xia X.G., Zhou H., Samper E., Melov S., and Xu Z. Pol II-expressed shRNA knocks down Sod2 gene expression and causes phenotypes of the gene knockout in mice. PLoS Genet. (2006) 2-10
-
(2006)
PLoS Genet.
, pp. 2-10
-
-
Xia, X.G.1
Zhou, H.2
Samper, E.3
Melov, S.4
Xu, Z.5
-
66
-
-
28244454785
-
Aconitase is the main functional target of aging in the citric acid cycle of kidney mitochondria from mice
-
Yarian C.S., Toroser D., and Sohal R.S. Aconitase is the main functional target of aging in the citric acid cycle of kidney mitochondria from mice. Mech. Ageing Dev. 127 (2006) 79-84
-
(2006)
Mech. Ageing Dev.
, vol.127
, pp. 79-84
-
-
Yarian, C.S.1
Toroser, D.2
Sohal, R.S.3
|