-
1
-
-
0024002527
-
On the discovery of glutathione
-
Meister A. On the discovery of glutathione. Trends Biochem Sci. 1988;13:185-188.
-
(1988)
Trends Biochem Sci
, vol.13
, pp. 185-188
-
-
Meister, A.1
-
2
-
-
0018195287
-
The glutathione status of cells
-
Kosower NS, Kosower EM. The glutathione status of cells. Int Rev Cytol. 1978;54:109-160.
-
(1978)
Int Rev Cytol
, vol.54
, pp. 109-160
-
-
Kosower, N.S.1
Kosower, E.M.2
-
3
-
-
0034672943
-
Metabolism and functions of glutathione in brain
-
Dringen R. Metabolism and functions of glutathione in brain. Prog Neurobiol. 2000;62:649-671.
-
(2000)
Prog Neurobiol
, vol.62
, pp. 649-671
-
-
Dringen, R.1
-
4
-
-
0018776894
-
Hydroperoxide metabolism in mammalian organs
-
Chance B, Sies H, Boveris A. Hydroperoxide metabolism in mammalian organs. Physiol Rev. 1979;59:527-605.
-
(1979)
Physiol Rev
, vol.59
, pp. 527-605
-
-
Chance, B.1
Sies, H.2
Boveris, A.3
-
5
-
-
84996111069
-
-
Youdim MB, Ben-Shachar D, Riederer P. Is Parkinson's disease a progressive siderosis of substantia nigra resulting in iron and melanin induced neurodegeneration? Acta Neurol Scand Suppl. 1989;126:47-54.
-
Youdim MB, Ben-Shachar D, Riederer P. Is Parkinson's disease a progressive siderosis of substantia nigra resulting in iron and melanin induced neurodegeneration? Acta Neurol Scand Suppl. 1989;126:47-54.
-
-
-
-
6
-
-
0033029717
-
Nitration modifying function of proteins, hormones and neurotransmitters
-
Nakaki T, Fujii T. Nitration modifying function of proteins, hormones and neurotransmitters. Jpn J Pharmacol. 1999;79:125-129.
-
(1999)
Jpn J Pharmacol
, vol.79
, pp. 125-129
-
-
Nakaki, T.1
Fujii, T.2
-
8
-
-
33846863589
-
Nitric oxide and peroxynitrite in health and disease
-
Pacher P, Beckman JS, Liaudet L. Nitric oxide and peroxynitrite in health and disease. Physiol Rev. 2007;87:315-424.
-
(2007)
Physiol Rev
, vol.87
, pp. 315-424
-
-
Pacher, P.1
Beckman, J.S.2
Liaudet, L.3
-
9
-
-
0028641246
-
Peroxynitrite versus hydroxyl radical: The role of nitric oxide in superoxide-dependent cerebral injury
-
Beckman JS. Peroxynitrite versus hydroxyl radical: the role of nitric oxide in superoxide-dependent cerebral injury. Ann N Y Acad Sci. 1994;738:69-75.
-
(1994)
Ann N Y Acad Sci
, vol.738
, pp. 69-75
-
-
Beckman, J.S.1
-
10
-
-
0025814980
-
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
-
Esterbauer H, Schaur RJ, Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med. 1991;11:81-128.
-
(1991)
Free Radic Biol Med
, vol.11
, pp. 81-128
-
-
Esterbauer, H.1
Schaur, R.J.2
Zollner, H.3
-
11
-
-
0032968517
-
4-Hydroxynonenal inhibits glutathione peroxidase: Protection by glutathione
-
Bosch-Morell F, Flohe L, Marin N, Romero FJ. 4-Hydroxynonenal inhibits glutathione peroxidase: protection by glutathione. Free Radic Biol Med. 1999;26:1383-1387.
-
(1999)
Free Radic Biol Med
, vol.26
, pp. 1383-1387
-
-
Bosch-Morell, F.1
Flohe, L.2
Marin, N.3
Romero, F.J.4
-
12
-
-
0029008428
-
Enzymes and transport systems involved in the formation and disposition of glutathione S-conjugates. Role in bioactivation and detoxication mechanisms of xenobiotics
-
Commandeur JN, Stijntjes GJ, Vermeulen NP. Enzymes and transport systems involved in the formation and disposition of glutathione S-conjugates. Role in bioactivation and detoxication mechanisms of xenobiotics. Pharmacol Rev. 1995;47:271-330.
-
(1995)
Pharmacol Rev
, vol.47
, pp. 271-330
-
-
Commandeur, J.N.1
Stijntjes, G.J.2
Vermeulen, N.P.3
-
13
-
-
0033948161
-
Cerebral antioxidant status and free radical generation following glutathione depletion and subsequent recovery
-
Gupta A, Gupta A, Datta M, Shukla GS. Cerebral antioxidant status and free radical generation following glutathione depletion and subsequent recovery. Mol Cell Biochem. 2000;209:55-61.
-
(2000)
Mol Cell Biochem
, vol.209
, pp. 55-61
-
-
Gupta, A.1
Gupta, A.2
Datta, M.3
Shukla, G.S.4
-
14
-
-
0025971259
-
Glutathione deficiency leads to mitochondrial damage in brain
-
Jain A, Martensson J, Stole E, Auld PA, Meister A. Glutathione deficiency leads to mitochondrial damage in brain. Proc Natl Acad Sci U S A. 1991;88:1913-1917.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 1913-1917
-
-
Jain, A.1
Martensson, J.2
Stole, E.3
Auld, P.A.4
Meister, A.5
-
15
-
-
34547490698
-
Role of endogenous glutathione in the secondary damage in experimental spinal cord injury in mice
-
Genovese T, Mazzon E, Esposito E, Muia C, Di Paola R, Di Bella P, et al. Role of endogenous glutathione in the secondary damage in experimental spinal cord injury in mice. Neurosci Lett. 2007;423:41-46.
-
(2007)
Neurosci Lett
, vol.423
, pp. 41-46
-
-
Genovese, T.1
Mazzon, E.2
Esposito, E.3
Muia, C.4
Di Paola, R.5
Di Bella, P.6
-
16
-
-
29444459269
-
Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse
-
Aoyama K, Suh SW, Hamby AM, Liu J, Chan WY, Chen Y, et al. Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse. Nat Neurosci. 2006;9:119-126.
-
(2006)
Nat Neurosci
, vol.9
, pp. 119-126
-
-
Aoyama, K.1
Suh, S.W.2
Hamby, A.M.3
Liu, J.4
Chan, W.Y.5
Chen, Y.6
-
17
-
-
0030792637
-
Multiple roles of glutathione in the central nervous system
-
Cooper AJ, Kristal BS. Multiple roles of glutathione in the central nervous system. Biol Chem. 1997;378:793-802.
-
(1997)
Biol Chem
, vol.378
, pp. 793-802
-
-
Cooper, A.J.1
Kristal, B.S.2
-
18
-
-
0028114890
-
The reaction of superoxide with reduced glutathione
-
Winterbourn CC, Metodiewa D. The reaction of superoxide with reduced glutathione. Arch Biochem Biophys. 1994;314:284-290.
-
(1994)
Arch Biochem Biophys
, vol.314
, pp. 284-290
-
-
Winterbourn, C.C.1
Metodiewa, D.2
-
19
-
-
0028287096
-
Nitric oxide reacts with intracellular glutathione and activates the hexose monophosphate shunt in human neutrophils: Evidence for S-nitrosoglutathione as a bioactive intermediary
-
Clancy RM, Levartovsky D, Leszczynska-Piziak J, Yegudin J, Abramson SB. Nitric oxide reacts with intracellular glutathione and activates the hexose monophosphate shunt in human neutrophils: evidence for S-nitrosoglutathione as a bioactive intermediary. Proc Natl Acad Sci U S A. 1994;91:3680-3684.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 3680-3684
-
-
Clancy, R.M.1
Levartovsky, D.2
Leszczynska-Piziak, J.3
Yegudin, J.4
Abramson, S.B.5
-
20
-
-
0031418498
-
Neurodegenerative disorders in humans: The role of glutathione in oxidative stress-mediated neuronal death
-
Bains JS, Shaw CA. Neurodegenerative disorders in humans: the role of glutathione in oxidative stress-mediated neuronal death. Brain Res Brain Res Rev. 1997;25:335-358.
-
(1997)
Brain Res Brain Res Rev
, vol.25
, pp. 335-358
-
-
Bains, J.S.1
Shaw, C.A.2
-
21
-
-
0032948006
-
Peroxynitrite-induced alterations in synaptosomal membrane proteins: Insight into oxidative stress in Alzheimer's disease
-
Koppal T, Drake J, Yatin S, Jordan B, Varadarajan S, Bettenhausen L, et al. Peroxynitrite-induced alterations in synaptosomal membrane proteins: insight into oxidative stress in Alzheimer's disease. J Neurochem. 1999;72:310-317.
-
(1999)
J Neurochem
, vol.72
, pp. 310-317
-
-
Koppal, T.1
Drake, J.2
Yatin, S.3
Jordan, B.4
Varadarajan, S.5
Bettenhausen, L.6
-
22
-
-
0030222319
-
Role of metallothionein and other antioxidants in scavenging superoxide radicals and their possible role in neuroprotection
-
Hussain S, Slikker W Jr, Ali SF. Role of metallothionein and other antioxidants in scavenging superoxide radicals and their possible role in neuroprotection. Neurochem Int. 1996;29:145-152.
-
(1996)
Neurochem Int
, vol.29
, pp. 145-152
-
-
Hussain, S.1
Slikker Jr, W.2
Ali, S.F.3
-
23
-
-
23644432822
-
The effects of stress and aging on glutathione metabolism
-
Maher P. The effects of stress and aging on glutathione metabolism. Ageing Res Rev. 2005;4:288-314.
-
(2005)
Ageing Res Rev
, vol.4
, pp. 288-314
-
-
Maher, P.1
-
24
-
-
0035371184
-
Redox environment of the cell as viewed through the redox state of the glutathione disulfide / glutathione couple
-
Schafer FQ, Buettner GR. Redox environment of the cell as viewed through the redox state of the glutathione disulfide / glutathione couple. Free Radic Biol Med. 2001;30:1191-1212.
-
(2001)
Free Radic Biol Med
, vol.30
, pp. 1191-1212
-
-
Schafer, F.Q.1
Buettner, G.R.2
-
25
-
-
0032533744
-
Glutathione transferase protects neuronal cultures against four hydroxynonenal toxicity
-
Xie C, Lovell MA, Markesbery WR. Glutathione transferase protects neuronal cultures against four hydroxynonenal toxicity. Free Radic Biol Med. 1998;25:979-988.
-
(1998)
Free Radic Biol Med
, vol.25
, pp. 979-988
-
-
Xie, C.1
Lovell, M.A.2
Markesbery, W.R.3
-
26
-
-
0034305689
-
Mechanisms of L-cysteine neurotoxicity
-
Janaky R, Varga V, Hermann A, Saransaari P, Oja SS. Mechanisms of L-cysteine neurotoxicity. Neurochem Res. 2000;25:1397-1405.
-
(2000)
Neurochem Res
, vol.25
, pp. 1397-1405
-
-
Janaky, R.1
Varga, V.2
Hermann, A.3
Saransaari, P.4
Oja, S.S.5
-
27
-
-
0017360297
-
Rat liver glutathione: Possible role as a reservoir of cysteine
-
Tateishi N, Higashi T, Naruse A, Nakashima K, Shiozaki H. Rat liver glutathione: possible role as a reservoir of cysteine. J Nutr. 1977;107:51-60.
-
(1977)
J Nutr
, vol.107
, pp. 51-60
-
-
Tateishi, N.1
Higashi, T.2
Naruse, A.3
Nakashima, K.4
Shiozaki, H.5
-
28
-
-
14044272119
-
S-glutathionylation: From redox regulation of protein functions to human diseases
-
Giustarini D, Rossi R, Milzani A, Colombo R, Dalle-Donne I. S-glutathionylation: from redox regulation of protein functions to human diseases. J Cell Mol Med. 2004;8:201-212.
-
(2004)
J Cell Mol Med
, vol.8
, pp. 201-212
-
-
Giustarini, D.1
Rossi, R.2
Milzani, A.3
Colombo, R.4
Dalle-Donne, I.5
-
29
-
-
0345329603
-
Glutathione and signal transduction in the mammalian CNS
-
Janaky R, Ogita K, Pasqualotto BA, Bains JS, Oja SS, Yoneda Y, et al. Glutathione and signal transduction in the mammalian CNS. J Neurochem. 1999;73:889-902.
-
(1999)
J Neurochem
, vol.73
, pp. 889-902
-
-
Janaky, R.1
Ogita, K.2
Pasqualotto, B.A.3
Bains, J.S.4
Oja, S.S.5
Yoneda, Y.6
-
30
-
-
0029780524
-
Mechanism of nitric oxide release from S-nitrosothiols
-
Singh RJ, Hogg N, Joseph J, Kalyanaraman B. Mechanism of nitric oxide release from S-nitrosothiols. J Biol Chem. 1996;271:18596-18603.
-
(1996)
J Biol Chem
, vol.271
, pp. 18596-18603
-
-
Singh, R.J.1
Hogg, N.2
Joseph, J.3
Kalyanaraman, B.4
-
31
-
-
0031889724
-
Neuroprotection by S-nitrosoglutathione of brain dopamine neurons from oxidative stress
-
Rauhala P, Lin AM, Chiueh CC. Neuroprotection by S-nitrosoglutathione of brain dopamine neurons from oxidative stress. FASEB J. 1998;12:165-173.
-
(1998)
FASEB J
, vol.12
, pp. 165-173
-
-
Rauhala, P.1
Lin, A.M.2
Chiueh, C.C.3
-
32
-
-
0029004836
-
De novo synthesis of glutathione is required for both entry into and progression through the cell cycle
-
Poot M, Teubert H, Rabinovitch PS, Kavanagh TJ. De novo synthesis of glutathione is required for both entry into and progression through the cell cycle. J Cell Physiol. 1995;163:555-560.
-
(1995)
J Cell Physiol
, vol.163
, pp. 555-560
-
-
Poot, M.1
Teubert, H.2
Rabinovitch, P.S.3
Kavanagh, T.J.4
-
33
-
-
36949024931
-
Glutathione induces neuronal differentiation in rat bone marrow stromal cells
-
Sagara J, Makino N. Glutathione induces neuronal differentiation in rat bone marrow stromal cells. Neurochem Res. 2008;33:16-21.
-
(2008)
Neurochem Res
, vol.33
, pp. 16-21
-
-
Sagara, J.1
Makino, N.2
-
34
-
-
0029033862
-
Mitochondrial changes associated with glutathione deficiency
-
Meister A. Mitochondrial changes associated with glutathione deficiency. Biochim Biophys Acta. 1995;1271:35-42.
-
(1995)
Biochim Biophys Acta
, vol.1271
, pp. 35-42
-
-
Meister, A.1
-
35
-
-
0020478933
-
Status of the mitochondrial pool of glutathione in the isolated hepatocyte
-
Meredith MJ, Reed DJ. Status of the mitochondrial pool of glutathione in the isolated hepatocyte. J Biol Chem. 1982;257:3747-3753.
-
(1982)
J Biol Chem
, vol.257
, pp. 3747-3753
-
-
Meredith, M.J.1
Reed, D.J.2
-
36
-
-
0016635533
-
Regulation of gamma-glutamylcysteine synthetase by nonallosteric feedback inhibition by glutathione
-
Richman PG, Meister A. Regulation of gamma-glutamylcysteine synthetase by nonallosteric feedback inhibition by glutathione. J Biol Chem. 1975;250:1422-1426.
-
(1975)
J Biol Chem
, vol.250
, pp. 1422-1426
-
-
Richman, P.G.1
Meister, A.2
-
37
-
-
0021149767
-
Reversible dissociation of gamma-glutamylcysteine synthetase into two subunits
-
Seelig GF, Simondsen RP, Meister A. Reversible dissociation of gamma-glutamylcysteine synthetase into two subunits. J Biol Chem. 1984;259:9345-9347.
-
(1984)
J Biol Chem
, vol.259
, pp. 9345-9347
-
-
Seelig, G.F.1
Simondsen, R.P.2
Meister, A.3
-
38
-
-
5344280431
-
Genetically altered mice to evaluate glutathione homeostasis in health and disease
-
Dalton TP, Chen Y, Schneider SN, Nebert DW, Shertzer HG. Genetically altered mice to evaluate glutathione homeostasis in health and disease. Free Radic Biol Med. 2004;37:1511-1526.
-
(2004)
Free Radic Biol Med
, vol.37
, pp. 1511-1526
-
-
Dalton, T.P.1
Chen, Y.2
Schneider, S.N.3
Nebert, D.W.4
Shertzer, H.G.5
-
39
-
-
0037147240
-
-
Yang Y, Dieter MZ, Chen Y, Shertzer HG, Nebert DW, Dalton TP. J Biol Chem. 2002;277:49446-49452.
-
(2002)
J Biol Chem
, vol.277
, pp. 49446-49452
-
-
Yang, Y.1
Dieter, M.Z.2
Chen, Y.3
Shertzer, H.G.4
Nebert, D.W.5
Dalton, T.P.6
-
40
-
-
0030600535
-
Transcriptional regulation of gamma-glutamylcysteine synthetase-heavy subunit by oxidants in human alveolar epithelial cells
-
Rahman I, Bel A, Mulier B, Lawson MF, Harrison DJ, Macnee W, et al. Transcriptional regulation of gamma-glutamylcysteine synthetase-heavy subunit by oxidants in human alveolar epithelial cells. Biochem Biophys Res Commun. 1996;229:832-837.
-
(1996)
Biochem Biophys Res Commun
, vol.229
, pp. 832-837
-
-
Rahman, I.1
Bel, A.2
Mulier, B.3
Lawson, M.F.4
Harrison, D.J.5
Macnee, W.6
-
41
-
-
0032951247
-
The induction of GSH synthesis by nanomolar concentrations of NO in endothelial cells: A role for gammaglutamylcysteine synthetase and gamma-glutamyl transpeptidase
-
Moellering D, Mc Andrew J, Patel RP, Forman HJ, Mulcahy RT, Jo H, et al. The induction of GSH synthesis by nanomolar concentrations of NO in endothelial cells: a role for gammaglutamylcysteine synthetase and gamma-glutamyl transpeptidase. FEBS Lett. 1999;448:292-296.
-
(1999)
FEBS Lett
, vol.448
, pp. 292-296
-
-
Moellering, D.1
Mc Andrew, J.2
Patel, R.P.3
Forman, H.J.4
Mulcahy, R.T.5
Jo, H.6
-
42
-
-
0033555806
-
Synthesis of the antioxidant glutathione in neurons: Supply by astrocytes of CysGly as precursor for neuronal glutathione
-
Dringen R, Pfeiffer B, Hamprecht B. Synthesis of the antioxidant glutathione in neurons: supply by astrocytes of CysGly as precursor for neuronal glutathione. J Neurosci. 1999;19:562-569.
-
(1999)
J Neurosci
, vol.19
, pp. 562-569
-
-
Dringen, R.1
Pfeiffer, B.2
Hamprecht, B.3
-
43
-
-
0030606289
-
Different preferences in the utilization of amino acids for glutathione synthesis in cultured neurons and astroglial cells derived from rat brain
-
Kranich O, Hamprecht B, Dringen R. Different preferences in the utilization of amino acids for glutathione synthesis in cultured neurons and astroglial cells derived from rat brain. Neurosci Lett. 1996;219:211-214.
-
(1996)
Neurosci Lett
, vol.219
, pp. 211-214
-
-
Kranich, O.1
Hamprecht, B.2
Dringen, R.3
-
44
-
-
0023907144
-
Glutaminase in neurons and astrocytes cultured from mouse brain: Kinetic properties and effects of phosphate, glutamate, and ammonia
-
Hogstad S, Svenneby G, Torgner IA, Kvamme E, Hertz L, Schousboe A. Glutaminase in neurons and astrocytes cultured from mouse brain: kinetic properties and effects of phosphate, glutamate, and ammonia. Neurochem Res. 1988;13:383-388.
-
(1988)
Neurochem Res
, vol.13
, pp. 383-388
-
-
Hogstad, S.1
Svenneby, G.2
Torgner, I.A.3
Kvamme, E.4
Hertz, L.5
Schousboe, A.6
-
45
-
-
0019165593
-
Involvement of the cystathionine pathway in the biosynthesis of glutathione by isolated rat hepatocytes
-
Beatty PW, Reed DJ. Involvement of the cystathionine pathway in the biosynthesis of glutathione by isolated rat hepatocytes. Arch Biochem Biophys. 1980;204:80-87.
-
(1980)
Arch Biochem Biophys
, vol.204
, pp. 80-87
-
-
Beatty, P.W.1
Reed, D.J.2
-
46
-
-
3142758491
-
Murine cystathionine gamma-lyase: Complete cDNA and genomic sequences, promoter activity, tissue distribution and developmental expression
-
Ishii I, Akahoshi N, Yu XN, Kobayashi Y, Namekata K, Komaki G, et al. Murine cystathionine gamma-lyase: complete cDNA and genomic sequences, promoter activity, tissue distribution and developmental expression. Biochem J. 2004;381:113-123.
-
(2004)
Biochem J
, vol.381
, pp. 113-123
-
-
Ishii, I.1
Akahoshi, N.2
Yu, X.N.3
Kobayashi, Y.4
Namekata, K.5
Komaki, G.6
-
47
-
-
0033534361
-
N-acetylcysteine, but not methionine or 2-oxothiazolidine-4-carboxylate, serves as cysteine donor for the synthesis of glutathione in cultured neurons derived from embryonal rat brain
-
Dringen R, Hamprecht B. N-acetylcysteine, but not methionine or 2-oxothiazolidine-4-carboxylate, serves as cysteine donor for the synthesis of glutathione in cultured neurons derived from embryonal rat brain. Neurosci Lett. 1999;259:79-82.
-
(1999)
Neurosci Lett
, vol.259
, pp. 79-82
-
-
Dringen, R.1
Hamprecht, B.2
-
48
-
-
0035369252
-
The uptake of cysteine in cultured primary astrocytes and neurons
-
Shanker G, Allen JW, Mutkus LA, Aschner M. The uptake of cysteine in cultured primary astrocytes and neurons. Brain Res. 2001;902:156-163.
-
(2001)
Brain Res
, vol.902
, pp. 156-163
-
-
Shanker, G.1
Allen, J.W.2
Mutkus, L.A.3
Aschner, M.4
-
49
-
-
0027176433
-
Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/ glutamate cotransporters
-
Shafqat S, Tamarappoo BK, Kilberg MS, Puranam RS, McNamara JO, Guadano-Ferraz A, et al. Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/ glutamate cotransporters. J Biol Chem. 1993;268:15351-15355.
-
(1993)
J Biol Chem
, vol.268
, pp. 15351-15355
-
-
Shafqat, S.1
Tamarappoo, B.K.2
Kilberg, M.S.3
Puranam, R.S.4
McNamara, J.O.5
Guadano-Ferraz, A.6
-
50
-
-
0029888341
-
Cloning and functional characterization of a system ASC-like Na+-dependent neutral amino acid transporter
-
Utsunomiya-Tate N, Endou H, Kanai Y. Cloning and functional characterization of a system ASC-like Na+-dependent neutral amino acid transporter. J Biol Chem. 1996;271:14883-14890.
-
(1996)
J Biol Chem
, vol.271
, pp. 14883-14890
-
-
Utsunomiya-Tate, N.1
Endou, H.2
Kanai, Y.3
-
51
-
-
0043238712
-
Characterization of rapid and high-affinity uptake of L-serine in neurons and astrocytes in primary culture
-
Yamamoto T, Nishizaki I, Furuya S, Hirabayashi Y, Takahashi K, Okuyama S, et al. Characterization of rapid and high-affinity uptake of L-serine in neurons and astrocytes in primary culture. FEBS Lett. 2003;548:69-73.
-
(2003)
FEBS Lett
, vol.548
, pp. 69-73
-
-
Yamamoto, T.1
Nishizaki, I.2
Furuya, S.3
Hirabayashi, Y.4
Takahashi, K.5
Okuyama, S.6
-
52
-
-
0037343974
-
The glutamate transporters EAAT2 and EAAT3 mediate cysteine uptake in cortical neuron cultures
-
Chen Y, Swanson RA. The glutamate transporters EAAT2 and EAAT3 mediate cysteine uptake in cortical neuron cultures. J Neurochem. 2003;84:1332-1339.
-
(2003)
J Neurochem
, vol.84
, pp. 1332-1339
-
-
Chen, Y.1
Swanson, R.A.2
-
53
-
-
0347991771
-
Role of neuronal glutamate transporter in the cysteine uptake and intracellular glutathione levels in cultured cortical neurons
-
Himi T, Ikeda M, Yasuhara T, Nishida M, Morita I. Role of neuronal glutamate transporter in the cysteine uptake and intracellular glutathione levels in cultured cortical neurons. J Neural Transm. 2003;110:1337-1348.
-
(2003)
J Neural Transm
, vol.110
, pp. 1337-1348
-
-
Himi, T.1
Ikeda, M.2
Yasuhara, T.3
Nishida, M.4
Morita, I.5
-
54
-
-
0027421350
-
Maintenance of neuronal glutathione by glial cells
-
Sagara JI, Miura K, Bannai S. Maintenance of neuronal glutathione by glial cells. J Neurochem. 1993;61:1672-1676.
-
(1993)
J Neurochem
, vol.61
, pp. 1672-1676
-
-
Sagara, J.I.1
Miura, K.2
Bannai, S.3
-
55
-
-
0031788839
-
Glutathione restoration as indicator for cellular metabolism of astroglial cells
-
Dringen R, Hamprecht B. Glutathione restoration as indicator for cellular metabolism of astroglial cells. Dev Neurosci. 1998;20:401-407.
-
(1998)
Dev Neurosci
, vol.20
, pp. 401-407
-
-
Dringen, R.1
Hamprecht, B.2
-
56
-
-
0001412747
-
Astrocytes provide cysteine to neurons by releasing glutathione
-
Wang XF, Cynader MS. Astrocytes provide cysteine to neurons by releasing glutathione. J Neurochem. 2000;74:1434-1442.
-
(2000)
J Neurochem
, vol.74
, pp. 1434-1442
-
-
Wang, X.F.1
Cynader, M.S.2
-
57
-
-
0031004608
-
The gamma-glutamyl transpeptidase inhibitor acivicin preserves glutathione released by astroglial cells in culture
-
Dringen R, Kranich O, Hamprecht B. The gamma-glutamyl transpeptidase inhibitor acivicin preserves glutathione released by astroglial cells in culture. Neurochem Res. 1997;22:727-733.
-
(1997)
Neurochem Res
, vol.22
, pp. 727-733
-
-
Dringen, R.1
Kranich, O.2
Hamprecht, B.3
-
58
-
-
0030749694
-
Use of dipeptides for the synthesis of glutathione by astroglia-rich primary cultures
-
Dringen R, Kranich O, Loschmann PA, Hamprecht B. Use of dipeptides for the synthesis of glutathione by astroglia-rich primary cultures. J Neurochem. 1997;69:868-874.
-
(1997)
J Neurochem
, vol.69
, pp. 868-874
-
-
Dringen, R.1
Kranich, O.2
Loschmann, P.A.3
Hamprecht, B.4
-
59
-
-
33847687710
-
Gap junction hemichannel-mediated release of glutathione from cultured rat astrocytes
-
Rana S, Dringen R. Gap junction hemichannel-mediated release of glutathione from cultured rat astrocytes. Neurosci Lett. 2007;415:45-48.
-
(2007)
Neurosci Lett
, vol.415
, pp. 45-48
-
-
Rana, S.1
Dringen, R.2
-
60
-
-
0035577287
-
Aminopeptidase N mediates the utilization of the GSH precursor CysGly by cultured neurons
-
Dringen R, Gutterer JM, Gros C, Hirrlinger J. Aminopeptidase N mediates the utilization of the GSH precursor CysGly by cultured neurons. J Neurosci Res. 2001;66:1003-1008.
-
(2001)
J Neurosci Res
, vol.66
, pp. 1003-1008
-
-
Dringen, R.1
Gutterer, J.M.2
Gros, C.3
Hirrlinger, J.4
-
61
-
-
33749831751
-
Cystine/glutamate exchange modulates glutathione supply for neuroprotection from oxidative stress and cell proliferation
-
Shih AY, Erb H, Sun X, Toda S, Kalivas PW, Murphy TH. Cystine/glutamate exchange modulates glutathione supply for neuroprotection from oxidative stress and cell proliferation. J Neurosci. 2006;26:10514-10523.
-
(2006)
J Neurosci
, vol.26
, pp. 10514-10523
-
-
Shih, A.Y.1
Erb, H.2
Sun, X.3
Toda, S.4
Kalivas, P.W.5
Murphy, T.H.6
-
62
-
-
0027489346
-
Cystine uptake and glutathione level in fetal brain cells in primary culture and in suspension
-
Sagara J, Miura K, Bannai S. Cystine uptake and glutathione level in fetal brain cells in primary culture and in suspension. J Neurochem. 1993;61:1667-1671.
-
(1993)
J Neurochem
, vol.61
, pp. 1667-1671
-
-
Sagara, J.1
Miura, K.2
Bannai, S.3
-
63
-
-
0035045391
-
Visualising the activity of the cystine-glutamate antiporter in glial cells using antibodies to aminoadipic acid, a selectively transported substrate
-
Pow DV. Visualising the activity of the cystine-glutamate antiporter in glial cells using antibodies to aminoadipic acid, a selectively transported substrate. Glia. 2001;34:27-38.
-
(2001)
Glia
, vol.34
, pp. 27-38
-
-
Pow, D.V.1
-
64
-
-
33645217828
-
System Xc- and apolipoprotein E expressed by microglia have opposite effects on the neurotoxicity of amyloid-beta peptide 1-40
-
Qin S, Colin C, Hinners I, Gervais A, Cheret C, Mallat M. System Xc- and apolipoprotein E expressed by microglia have opposite effects on the neurotoxicity of amyloid-beta peptide 1-40. J Neurosci. 2006;26:3345-3356.
-
(2006)
J Neurosci
, vol.26
, pp. 3345-3356
-
-
Qin, S.1
Colin, C.2
Hinners, I.3
Gervais, A.4
Cheret, C.5
Mallat, M.6
-
65
-
-
0033597349
-
Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins
-
Sato H, Tamba M, Ishii T, Bannai S. Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins. J Biol Chem. 1999;274:11455-11458.
-
(1999)
J Biol Chem
, vol.274
, pp. 11455-11458
-
-
Sato, H.1
Tamba, M.2
Ishii, T.3
Bannai, S.4
-
66
-
-
0037107162
-
Distribution of cystine/glutamate exchange transporter, system x(c)-, in the mouse brain
-
Sato H, Tamba M, Okuno S, Sato K, Keino-Masu K, Masu M, et al. Distribution of cystine/glutamate exchange transporter, system x(c)-, in the mouse brain. J Neurosci. 2002;22:8028-8033.
-
(2002)
J Neurosci
, vol.22
, pp. 8028-8033
-
-
Sato, H.1
Tamba, M.2
Okuno, S.3
Sato, K.4
Keino-Masu, K.5
Masu, M.6
-
67
-
-
27844530663
-
Redox imbalance in cystine/glutamate transporter-deficient mice
-
Sato H, Shiiya A, Kimata M, Maebara K, Tamba M, Sakakura Y, et al. Redox imbalance in cystine/glutamate transporter-deficient mice. J Biol Chem. 2005;280:37423-37429.
-
(2005)
J Biol Chem
, vol.280
, pp. 37423-37429
-
-
Sato, H.1
Shiiya, A.2
Kimata, M.3
Maebara, K.4
Tamba, M.5
Sakakura, Y.6
-
68
-
-
0025355933
-
Immature cortical neurons are uniquely sensitive to glutamate toxicity by inhibition of cystine uptake
-
Murphy TH, Schnaar RL, Coyle JT. Immature cortical neurons are uniquely sensitive to glutamate toxicity by inhibition of cystine uptake. FASEB J. 1990;4:1624-1633.
-
(1990)
FASEB J
, vol.4
, pp. 1624-1633
-
-
Murphy, T.H.1
Schnaar, R.L.2
Coyle, J.T.3
-
69
-
-
34248190113
-
Expression and developmental regulation of the cystine/glutamate exchanger (xc-) in the rat
-
La Bella V, Valentino F, Piccoli T, Piccoli F. Expression and developmental regulation of the cystine/glutamate exchanger (xc-) in the rat. Neurochem Res. 2007;32:1081-1090.
-
(2007)
Neurochem Res
, vol.32
, pp. 1081-1090
-
-
La Bella, V.1
Valentino, F.2
Piccoli, T.3
Piccoli, F.4
-
70
-
-
0242469279
-
The glutamate and neutral amino acid transporter family: Physiological and pharmacological implications
-
Kanai Y, Hediger MA. The glutamate and neutral amino acid transporter family: physiological and pharmacological implications. Eur J Pharmacol. 2003;479:237-247.
-
(2003)
Eur J Pharmacol
, vol.479
, pp. 237-247
-
-
Kanai, Y.1
Hediger, M.A.2
-
71
-
-
1842524064
-
Glutamate transporters: Animal models to neurologic disease
-
Maragakis NJ, Rothstein JD. Glutamate transporters: animal models to neurologic disease. Neurobiol Dis. 2004;15:461-473.
-
(2004)
Neurobiol Dis
, vol.15
, pp. 461-473
-
-
Maragakis, N.J.1
Rothstein, J.D.2
-
72
-
-
14044263640
-
Small-scale molecular motions accomplish glutamate uptake in human glutamate transporters
-
Koch HP, Larsson HP. Small-scale molecular motions accomplish glutamate uptake in human glutamate transporters. J Neurosci. 2005;25:1730-1736.
-
(2005)
J Neurosci
, vol.25
, pp. 1730-1736
-
-
Koch, H.P.1
Larsson, H.P.2
-
73
-
-
7244254186
-
Structure of a glutamate transporter homologue from Pyrococcus horikoshii
-
Yernool D, Boudker O, Jin Y, Gouaux E. Structure of a glutamate transporter homologue from Pyrococcus horikoshii. Nature. 2004;431:811-818.
-
(2004)
Nature
, vol.431
, pp. 811-818
-
-
Yernool, D.1
Boudker, O.2
Jin, Y.3
Gouaux, E.4
-
74
-
-
13344286293
-
Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate
-
Rothstein JD, Dykes-Hoberg M, Pardo CA, Bristol LA, Jin L, Kuncl RW, et al. Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate. Neuron. 1996;16:675-686.
-
(1996)
Neuron
, vol.16
, pp. 675-686
-
-
Rothstein, J.D.1
Dykes-Hoberg, M.2
Pardo, C.A.3
Bristol, L.A.4
Jin, L.5
Kuncl, R.W.6
-
75
-
-
0028060648
-
Localization of neuronal and glial glutamate transporters
-
Rothstein JD, Martin L, Levey AI, Dykes-Hoberg M, Jin L, Wu D, et al. Localization of neuronal and glial glutamate transporters. Neuron. 1994;13:713-725.
-
(1994)
Neuron
, vol.13
, pp. 713-725
-
-
Rothstein, J.D.1
Martin, L.2
Levey, A.I.3
Dykes-Hoberg, M.4
Jin, L.5
Wu, D.6
-
76
-
-
0029891464
-
Interaction of L-cysteine with a human excitatory amino acid transporter
-
Zerangue N, Kavanaugh MP. Interaction of L-cysteine with a human excitatory amino acid transporter. J Physiol. 1996;493 (Pt 2):419-423.
-
(1996)
J Physiol
, vol.493
, Issue.PART 2
, pp. 419-423
-
-
Zerangue, N.1
Kavanaugh, M.P.2
-
77
-
-
4544366121
-
Rapid trafficking of the neuronal glutamate transporter, EAAC1: Evidence for distinct trafficking pathways differentially regulated by protein kinase C and platelet-derived growth factor
-
Fournier KM, Gonzalez MI, Robinson MB. Rapid trafficking of the neuronal glutamate transporter, EAAC1: evidence for distinct trafficking pathways differentially regulated by protein kinase C and platelet-derived growth factor. J Biol Chem. 2004;279:34505-34513.
-
(2004)
J Biol Chem
, vol.279
, pp. 34505-34513
-
-
Fournier, K.M.1
Gonzalez, M.I.2
Robinson, M.B.3
-
78
-
-
0032053985
-
Multiple signaling pathways regulate cell surface expression and activity of the excitatory amino acid carrier 1 subtype of Glu transporter in C6 glioma
-
Davis KE, Straff DJ, Weinstein EA, Bannerman PG, Correale DM, Rothstein JD, et al. Multiple signaling pathways regulate cell surface expression and activity of the excitatory amino acid carrier 1 subtype of Glu transporter in C6 glioma. J Neurosci. 1998;18:2475-2485.
-
(1998)
J Neurosci
, vol.18
, pp. 2475-2485
-
-
Davis, K.E.1
Straff, D.J.2
Weinstein, E.A.3
Bannerman, P.G.4
Correale, D.M.5
Rothstein, J.D.6
-
79
-
-
2442709321
-
Retinal colocalization and in vitro interaction of the glutamate transporter EAAT3 and the serum- and glucocorticoid-inducible kinase SGK1 [correction]
-
Schniepp R, Kohler K, Ladewig T, Guenther E, Henke G, Palmada M, et al. Retinal colocalization and in vitro interaction of the glutamate transporter EAAT3 and the serum- and glucocorticoid-inducible kinase SGK1 [correction]. Invest Ophthalmol Vis Sci. 2004;45:1442-1449.
-
(2004)
Invest Ophthalmol Vis Sci
, vol.45
, pp. 1442-1449
-
-
Schniepp, R.1
Kohler, K.2
Ladewig, T.3
Guenther, E.4
Henke, G.5
Palmada, M.6
-
80
-
-
33845604392
-
Reduced intestinal and renal amino acid transport in PDK1 hypomorphic mice
-
Rexhepaj R, Grahammer F, Volkl H, Remy C, Wagner CA, Sandulache D, et al. Reduced intestinal and renal amino acid transport in PDK1 hypomorphic mice. Faseb J. 2006;20:2214-2222.
-
(2006)
Faseb J
, vol.20
, pp. 2214-2222
-
-
Rexhepaj, R.1
Grahammer, F.2
Volkl, H.3
Remy, C.4
Wagner, C.A.5
Sandulache, D.6
-
81
-
-
33745879804
-
Regulation of the glutamate transporter EAAC1 by expression and activation of delta-opioid receptor
-
Xia P, Pei G, Schwarz W. Regulation of the glutamate transporter EAAC1 by expression and activation of delta-opioid receptor. Eur J Neurosci. 2006;24:87-93.
-
(2006)
Eur J Neurosci
, vol.24
, pp. 87-93
-
-
Xia, P.1
Pei, G.2
Schwarz, W.3
-
82
-
-
0035282612
-
Modulation of the neuronal glutamate transporter EAAC1 by the interacting protein GTRAP3-18
-
Lin CI, Orlov I, Ruggiero AM, Dykes-Hoberg M, Lee A, Jackson M, et al. Modulation of the neuronal glutamate transporter EAAC1 by the interacting protein GTRAP3-18. Nature. 2001;410:84-88.
-
(2001)
Nature
, vol.410
, pp. 84-88
-
-
Lin, C.I.1
Orlov, I.2
Ruggiero, A.M.3
Dykes-Hoberg, M.4
Lee, A.5
Jackson, M.6
-
83
-
-
26944493785
-
Evidence that Akt mediates platelet-derived growth factor-dependent increases in activity and surface expression of the neuronal glutamate transporter, EAAC1
-
Krizman-Genda E, Gonzalez MI, Zelenaia O, Robinson MB. Evidence that Akt mediates platelet-derived growth factor-dependent increases in activity and surface expression of the neuronal glutamate transporter, EAAC1. Neuropharmacology. 2005;49:872-882.
-
(2005)
Neuropharmacology
, vol.49
, pp. 872-882
-
-
Krizman-Genda, E.1
Gonzalez, M.I.2
Zelenaia, O.3
Robinson, M.B.4
-
84
-
-
33646169431
-
A carboxyl-terminal determinant of the neuronal glutamate transporter, EAAC1, is required for platelet-derived growth factor-dependent trafficking
-
Sheldon AL, Gonzalez MI, Robinson MB. A carboxyl-terminal determinant of the neuronal glutamate transporter, EAAC1, is required for platelet-derived growth factor-dependent trafficking. J Biol Chem. 2006;281:4876-4886.
-
(2006)
J Biol Chem
, vol.281
, pp. 4876-4886
-
-
Sheldon, A.L.1
Gonzalez, M.I.2
Robinson, M.B.3
-
85
-
-
0036784075
-
Regulation of the neuronal glutamate transporter excitatory amino acid carrier-1 (EAAC1) by different protein kinase C subtypes
-
Gonzalez MI, Kazanietz MG, Robinson MB. Regulation of the neuronal glutamate transporter excitatory amino acid carrier-1 (EAAC1) by different protein kinase C subtypes. Mol Pharmacol. 2002;62:901-910.
-
(2002)
Mol Pharmacol
, vol.62
, pp. 901-910
-
-
Gonzalez, M.I.1
Kazanietz, M.G.2
Robinson, M.B.3
-
86
-
-
0037195777
-
Protein kinase C activation decreases cell surface expression of the GLT-1 subtype of glutamate transporter. Requirement of a carboxyl-terminal domain and partial dependence on serine 486
-
Kalandadze A, Wu Y, Robinson MB. Protein kinase C activation decreases cell surface expression of the GLT-1 subtype of glutamate transporter. Requirement of a carboxyl-terminal domain and partial dependence on serine 486. J Biol Chem. 2002;277:45741-45750.
-
(2002)
J Biol Chem
, vol.277
, pp. 45741-45750
-
-
Kalandadze, A.1
Wu, Y.2
Robinson, M.B.3
-
87
-
-
33846023049
-
Critical role of serine 465 in isoflurane-induced increase of cell-surface redistribution and activity of glutamate transporter type 3
-
Huang Y, Feng X, Sando JJ, Zuo Z. Critical role of serine 465 in isoflurane-induced increase of cell-surface redistribution and activity of glutamate transporter type 3. J Biol Chem. 2006;281:38133-38138.
-
(2006)
J Biol Chem
, vol.281
, pp. 38133-38138
-
-
Huang, Y.1
Feng, X.2
Sando, J.J.3
Zuo, Z.4
-
88
-
-
1642494714
-
Arginine 445 controls the coupling between glutamate and cations in the neuronal transporter EAAC-1
-
Borre L, Kanner BI. Arginine 445 controls the coupling between glutamate and cations in the neuronal transporter EAAC-1. J Biol Chem. 2004;279:2513-2519.
-
(2004)
J Biol Chem
, vol.279
, pp. 2513-2519
-
-
Borre, L.1
Kanner, B.I.2
-
89
-
-
41949122637
-
Reticulon RTN2B Regulates Trafficking and Function of Neuronal Glutamate Transporter EAAC1
-
Liu Y, Vidensky S, Ruggiero AM, Maier S, Sitte HH, Rothstein JD. Reticulon RTN2B Regulates Trafficking and Function of Neuronal Glutamate Transporter EAAC1. J Biol Chem. 2008;283:6561-6571.
-
(2008)
J Biol Chem
, vol.283
, pp. 6561-6571
-
-
Liu, Y.1
Vidensky, S.2
Ruggiero, A.M.3
Maier, S.4
Sitte, H.H.5
Rothstein, J.D.6
-
90
-
-
58649109347
-
GTRAP3-18 serves as a negative regulator of Rab1 in protein transport and neuronal differentiation
-
In press
-
Maier S, Reiterer V, Ruggiero AM, Rothstein JD, Thomas S, Dahm R, et al. GTRAP3-18 serves as a negative regulator of Rab1 in protein transport and neuronal differentiation. J Cell Mol Med. In press 2008.
-
(2008)
J Cell Mol Med
-
-
Maier, S.1
Reiterer, V.2
Ruggiero, A.M.3
Rothstein, J.D.4
Thomas, S.5
Dahm, R.6
-
91
-
-
39149115676
-
C6 glioma cells differentiated by retinoic acid overexpress the glutamate transporter excitatory amino acid carrier 1 (EAAC1)
-
Bianchi MG, Gazzola GC, Tognazzi L, Bussolati O. C6 glioma cells differentiated by retinoic acid overexpress the glutamate transporter excitatory amino acid carrier 1 (EAAC1). Neuroscience. 2008;151:1042-1052.
-
(2008)
Neuroscience
, vol.151
, pp. 1042-1052
-
-
Bianchi, M.G.1
Gazzola, G.C.2
Tognazzi, L.3
Bussolati, O.4
-
92
-
-
41949115734
-
The Endoplasmic Reticulum Exit of Glutamate Transporter Is Regulated by the Inducible Mammalian Yip6b/GTRAP3-18 Protein
-
Ruggiero AM, Liu Y, Vidensky S, Maier S, Jung E, Farhan H, et al. The Endoplasmic Reticulum Exit of Glutamate Transporter Is Regulated by the Inducible Mammalian Yip6b/GTRAP3-18 Protein. J Biol Chem. 2008;283:6175-6183.
-
(2008)
J Biol Chem
, vol.283
, pp. 6175-6183
-
-
Ruggiero, A.M.1
Liu, Y.2
Vidensky, S.3
Maier, S.4
Jung, E.5
Farhan, H.6
-
93
-
-
0037113345
-
Identification of addicsin /GTRAP3-18 as a chronic morphine-augmented gene in amygdala
-
Ikemoto MJ, Inoue K, Akiduki S, Osugi T, Imamura T, Ishida N, et al. Identification of addicsin /GTRAP3-18 as a chronic morphine-augmented gene in amygdala. Neuroreport. 2002;13:2079-2084.
-
(2002)
Neuroreport
, vol.13
, pp. 2079-2084
-
-
Ikemoto, M.J.1
Inoue, K.2
Akiduki, S.3
Osugi, T.4
Imamura, T.5
Ishida, N.6
-
94
-
-
2342541829
-
The mechanism of JWA gene involved in oxidative stress of cells
-
text in Chinese with English abstract
-
Wang NP, Zhou JW, Li AP, Cao HX, Wang XR. [The mechanism of JWA gene involved in oxidative stress of cells.] Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2003;21:212-215. (text in Chinese with English abstract)
-
(2003)
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
, vol.21
, pp. 212-215
-
-
Wang, N.P.1
Zhou, J.W.2
Li, A.P.3
Cao, H.X.4
Wang, X.R.5
-
95
-
-
4243064887
-
Expressions of JWA protein and heat stress protein 70 induced by cell differentiation inducers combined with heat stress in K562 cells
-
text in Chinese with English abstract
-
Mao WG, Li AP, Ye J, Huang S, Li AQ, Zhou JW. [Expressions of JWA protein and heat stress protein 70 induced by cell differentiation inducers combined with heat stress in K562 cells.] Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2004;22:60-63. (text in Chinese with English abstract)
-
(2004)
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
, vol.22
, pp. 60-63
-
-
Mao, W.G.1
Li, A.P.2
Ye, J.3
Huang, S.4
Li, A.Q.5
Zhou, J.W.6
-
96
-
-
35548946779
-
Regulation of glutathione synthesis via interaction between glutamate transport-associated protein 3-18 (GTRAP3-18) and excitatory amino acid carrier-1 (EAAC1) at plasma membrane
-
Watabe M, Aoyama K, Nakaki T. Regulation of glutathione synthesis via interaction between glutamate transport-associated protein 3-18 (GTRAP3-18) and excitatory amino acid carrier-1 (EAAC1) at plasma membrane. Mol Pharmacol. 2007;72:1103-1110.
-
(2007)
Mol Pharmacol
, vol.72
, pp. 1103-1110
-
-
Watabe, M.1
Aoyama, K.2
Nakaki, T.3
-
97
-
-
56649119569
-
A dominant role of GTRAP3-18 in neuronal glutathione synthesis
-
Watabe M, Aoyama K, Nakaki T. A dominant role of GTRAP3-18 in neuronal glutathione synthesis. J Neurosci. 2008;28:9404-9413.
-
(2008)
J Neurosci
, vol.28
, pp. 9404-9413
-
-
Watabe, M.1
Aoyama, K.2
Nakaki, T.3
-
98
-
-
0026027159
-
High-dose intravenous glutathione in man. Pharmacokinetics and effects on cyst(e)ine in plasma and urine
-
Aebi S, Assereto R, Lauterburg BH. High-dose intravenous glutathione in man. Pharmacokinetics and effects on cyst(e)ine in plasma and urine. Eur J Clin Invest. 1991;21:103-110.
-
(1991)
Eur J Clin Invest
, vol.21
, pp. 103-110
-
-
Aebi, S.1
Assereto, R.2
Lauterburg, B.H.3
-
99
-
-
0018175411
-
Blood-brain barrier restriction of peptides and the low uptake of enkephalins
-
Cornford EM, Braun LD, Crane PD, Oldendorf WH. Blood-brain barrier restriction of peptides and the low uptake of enkephalins. Endocrinology. 1978;103:1297-1303.
-
(1978)
Endocrinology
, vol.103
, pp. 1297-1303
-
-
Cornford, E.M.1
Braun, L.D.2
Crane, P.D.3
Oldendorf, W.H.4
-
100
-
-
33846418007
-
Characterization of intracellular elevation of glutathione (GSH) with glutathione monoethyl ester and GSH in brain and neuronal cultures: Relevance to Parkinson's disease
-
Zeevalk GD, Manzino L, Sonsalla PK, Bernard LP. Characterization of intracellular elevation of glutathione (GSH) with glutathione monoethyl ester and GSH in brain and neuronal cultures: relevance to Parkinson's disease. Exp Neurol. 2007;203:512-520.
-
(2007)
Exp Neurol
, vol.203
, pp. 512-520
-
-
Zeevalk, G.D.1
Manzino, L.2
Sonsalla, P.K.3
Bernard, L.P.4
-
101
-
-
0029942499
-
Evidence for the existence of a sodium-dependent glutathione (GSH) transporter. Expression of bovine brain capillary mRNA and size fractions in Xenopus laevis oocytes and dissociation from gamma-glutamyltranspeptidase and facilitative GSH transporters
-
Kannan R, Yi JR, Tang D, Li Y, Zlokovic BV, Kaplowitz N. Evidence for the existence of a sodium-dependent glutathione (GSH) transporter. Expression of bovine brain capillary mRNA and size fractions in Xenopus laevis oocytes and dissociation from gamma-glutamyltranspeptidase and facilitative GSH transporters. J Biol Chem. 1996;271:9754-9758.
-
(1996)
J Biol Chem
, vol.271
, pp. 9754-9758
-
-
Kannan, R.1
Yi, J.R.2
Tang, D.3
Li, Y.4
Zlokovic, B.V.5
Kaplowitz, N.6
-
102
-
-
0030273666
-
Reduced intravenous glutathione in the treatment of early Parkinson's disease
-
Sechi G, Deledda MG, Bua G, Satta WM, Deiana GA, Pes GM, et al. Reduced intravenous glutathione in the treatment of early Parkinson's disease. Prog Neuropsychopharmacol Biol Psychiatry. 1996;20:1159-1170.
-
(1996)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.20
, pp. 1159-1170
-
-
Sechi, G.1
Deledda, M.G.2
Bua, G.3
Satta, W.M.4
Deiana, G.A.5
Pes, G.M.6
-
103
-
-
0024546827
-
Modulation of endothelial GSH concentrations: Effect of exogenous GSH and GSH monoethyl ester
-
Tsan MF, White JE, Rosano CL. Modulation of endothelial GSH concentrations: effect of exogenous GSH and GSH monoethyl ester. J Appl Physiol. 1989;66:1029-1034.
-
(1989)
J Appl Physiol
, vol.66
, pp. 1029-1034
-
-
Tsan, M.F.1
White, J.E.2
Rosano, C.L.3
-
104
-
-
0028063294
-
Intracellular glutathione (GSH) levels modulate mercuric chloride (MC)- and methylmercuric chloride (MeHgCl)-induced amino acid release from neonatal rat primary astrocytes cultures
-
Aschner M, Mullaney KJ, Wagoner D, Lash LH, Kimelberg HK. Intracellular glutathione (GSH) levels modulate mercuric chloride (MC)- and methylmercuric chloride (MeHgCl)-induced amino acid release from neonatal rat primary astrocytes cultures. Brain Res. 1994;664:133-140.
-
(1994)
Brain Res
, vol.664
, pp. 133-140
-
-
Aschner, M.1
Mullaney, K.J.2
Wagoner, D.3
Lash, L.H.4
Kimelberg, H.K.5
-
105
-
-
0026665103
-
Increase in rat brain glutathione following intracerebroventricular administration of gammaglutamylcysteine
-
Pileblad E, Magnusson T. Increase in rat brain glutathione following intracerebroventricular administration of gammaglutamylcysteine. Biochem Pharmacol. 1992;44:895-903.
-
(1992)
Biochem Pharmacol
, vol.44
, pp. 895-903
-
-
Pileblad, E.1
Magnusson, T.2
-
106
-
-
0029562683
-
Neurotoxicity of cysteine: Interaction with glutamate
-
Puka-Sundvall M, Eriksson P, Nilsson M, Sandberg M, Lehmann A. Neurotoxicity of cysteine: interaction with glutamate. Brain Res. 1995;705:65-70.
-
(1995)
Brain Res
, vol.705
, pp. 65-70
-
-
Puka-Sundvall, M.1
Eriksson, P.2
Nilsson, M.3
Sandberg, M.4
Lehmann, A.5
-
107
-
-
0026043122
-
Antioxidant activity and other mechanisms of thiols involved in chemoprevention of mutation and cancer
-
De Flora S, Izzotti A, D'Agostini F, Cesarone CF. Antioxidant activity and other mechanisms of thiols involved in chemoprevention of mutation and cancer. Am J Med. 1991;91:122S-130S.
-
(1991)
Am J Med
, vol.91
-
-
De Flora, S.1
Izzotti, A.2
D'Agostini, F.3
Cesarone, C.F.4
-
108
-
-
0037414415
-
N-Acetyl cysteine protects against injury in a rat model of focal cerebral ischemia
-
Sekhon B, Sekhon C, Khan M, Patel SJ, Singh I, Singh AK. N-Acetyl cysteine protects against injury in a rat model of focal cerebral ischemia. Brain Res. 2003;971:1-8.
-
(2003)
Brain Res
, vol.971
, pp. 1-8
-
-
Sekhon, B.1
Sekhon, C.2
Khan, M.3
Patel, S.J.4
Singh, I.5
Singh, A.K.6
-
109
-
-
1642462339
-
Sensory neuroprotection, mitochondrial preservation, and therapeutic potential of N-acetyl-cysteine after nerve injury
-
Hart AM, Terenghi G, Kellerth JO, Wiberg M. Sensory neuroprotection, mitochondrial preservation, and therapeutic potential of N-acetyl-cysteine after nerve injury. Neuroscience. 2004;125:91-101.
-
(2004)
Neuroscience
, vol.125
, pp. 91-101
-
-
Hart, A.M.1
Terenghi, G.2
Kellerth, J.O.3
Wiberg, M.4
-
110
-
-
37748999265
-
Oxidative stress on EAAC1 is involved in MPTP-induced glutathione depletion and motor dysfunction
-
Aoyama K, Matsumura N, Watabe M, Nakaki T. Oxidative stress on EAAC1 is involved in MPTP-induced glutathione depletion and motor dysfunction. Eur J Neurosci. 2008;27:20-30.
-
(2008)
Eur J Neurosci
, vol.27
, pp. 20-30
-
-
Aoyama, K.1
Matsumura, N.2
Watabe, M.3
Nakaki, T.4
-
111
-
-
3142514196
-
Oxidative stress in neurodegeneration: Cause or consequence?
-
Andersen JK. Oxidative stress in neurodegeneration: cause or consequence? Nat Med. 2004;10 Suppl:S18-S25.
-
(2004)
Nat Med
, vol.10
, Issue.SUPPL.
-
-
Andersen, J.K.1
-
112
-
-
0034098189
-
Lipoperoxidation is selectively involved in progressive supranuclear palsy
-
Odetti P, Garibaldi S, Norese R, Angelini G, Marinelli L, Valentini S, et al. Lipoperoxidation is selectively involved in progressive supranuclear palsy. J Neuropathol Exp Neurol. 2000;59:393-397.
-
(2000)
J Neuropathol Exp Neurol
, vol.59
, pp. 393-397
-
-
Odetti, P.1
Garibaldi, S.2
Norese, R.3
Angelini, G.4
Marinelli, L.5
Valentini, S.6
-
113
-
-
0043172468
-
4-hydroxynonenal and neurodegenerative diseases
-
Zarkovic K. 4-hydroxynonenal and neurodegenerative diseases. Mol Aspects Med. 2003;24:293-303.
-
(2003)
Mol Aspects Med
, vol.24
, pp. 293-303
-
-
Zarkovic, K.1
-
114
-
-
0033954991
-
Oxidative stress and Alzheimer disease
-
Christen Y. Oxidative stress and Alzheimer disease. Am J Clin Nutr. 2000;71:621S-629S.
-
(2000)
Am J Clin Nutr
, vol.71
-
-
Christen, Y.1
-
115
-
-
0034052607
-
Oxidative insults are associated with apolipoprotein E genotype in Alzheimer's disease brain
-
Ramassamy C, Averill D, Beffert U, Theroux L, Lussier-Cacan S, Cohn JS, et al. Oxidative insults are associated with apolipoprotein E genotype in Alzheimer's disease brain. Neurobiol Dis. 2000;7:23-37.
-
(2000)
Neurobiol Dis
, vol.7
, pp. 23-37
-
-
Ramassamy, C.1
Averill, D.2
Beffert, U.3
Theroux, L.4
Lussier-Cacan, S.5
Cohn, J.S.6
-
116
-
-
39749157595
-
Peripheral levels of glutathione and protein oxidation as markers in the development of Alzheimer's disease from Mild Cognitive Impairment
-
Bermejo P, Martin-Aragon S, Benedi J, Susin C, Felici E, Gil P, et al. Peripheral levels of glutathione and protein oxidation as markers in the development of Alzheimer's disease from Mild Cognitive Impairment. Free Radic Res. 2008;42:162-170.
-
(2008)
Free Radic Res
, vol.42
, pp. 162-170
-
-
Bermejo, P.1
Martin-Aragon, S.2
Benedi, J.3
Susin, C.4
Felici, E.5
Gil, P.6
-
117
-
-
0031678044
-
Decreased glutathione transferase activity in brain and ventricular fluid in Alzheimer's disease
-
Lovell MA, Xie C, Markesbery WR. Decreased glutathione transferase activity in brain and ventricular fluid in Alzheimer's disease. Neurology. 1998;51:1562-1566.
-
(1998)
Neurology
, vol.51
, pp. 1562-1566
-
-
Lovell, M.A.1
Xie, C.2
Markesbery, W.R.3
-
118
-
-
0028075410
-
Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia
-
Sian J, Dexter DT, Lees AJ, Daniel S, Agid Y, Javoy-Agid F, et al. Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia. Ann Neurol. 1994;36:348-355.
-
(1994)
Ann Neurol
, vol.36
, pp. 348-355
-
-
Sian, J.1
Dexter, D.T.2
Lees, A.J.3
Daniel, S.4
Agid, Y.5
Javoy-Agid, F.6
-
119
-
-
0028059308
-
Oxidative damage in neurodegenerative disease
-
Jenner P. Oxidative damage in neurodegenerative disease. Lancet. 1994;344:796-798.
-
(1994)
Lancet
, vol.344
, pp. 796-798
-
-
Jenner, P.1
-
120
-
-
0035370304
-
New insights into progressive supranuclear palsy
-
Albers DS, Augood SJ. New insights into progressive supranuclear palsy. Trends Neurosci. 2001;24:347-353.
-
(2001)
Trends Neurosci
, vol.24
, pp. 347-353
-
-
Albers, D.S.1
Augood, S.J.2
-
121
-
-
0141836959
-
Nigral glutathione deficiency is not specific for idiopathic Parkinson's disease
-
Fitzmaurice PS, Ang L, Guttman M, Rajput AH, Furukawa Y, Kish SJ. Nigral glutathione deficiency is not specific for idiopathic Parkinson's disease. Mov Disord. 2003;18:969-976.
-
(2003)
Mov Disord
, vol.18
, pp. 969-976
-
-
Fitzmaurice, P.S.1
Ang, L.2
Guttman, M.3
Rajput, A.H.4
Furukawa, Y.5
Kish, S.J.6
-
122
-
-
0037501731
-
Update on Parkinson disease
-
Siderowf A, Stern M. Update on Parkinson disease. Ann Intern Med. 2003;138:651-658.
-
(2003)
Ann Intern Med
, vol.138
, pp. 651-658
-
-
Siderowf, A.1
Stern, M.2
-
123
-
-
0033231437
-
Brain gamma-glutamyl cysteine synthetase (GCS) mRNA expression patterns correlate with regional-specific enzyme activities and glutathione levels
-
Kang Y, Viswanath V, Jha N, Qiao X, Mo JQ, Andersen JK. Brain gamma-glutamyl cysteine synthetase (GCS) mRNA expression patterns correlate with regional-specific enzyme activities and glutathione levels. J Neurosci Res. 1999;58:436-441.
-
(1999)
J Neurosci Res
, vol.58
, pp. 436-441
-
-
Kang, Y.1
Viswanath, V.2
Jha, N.3
Qiao, X.4
Mo, J.Q.5
Andersen, J.K.6
-
124
-
-
0024537271
-
Reduction of brain glutathione by L-buthionine sulfoximine potentiates the dopamine-depleting action of 6-hydroxydopamine in rat striatum
-
Pileblad E, Magnusson T, Fornstedt B. Reduction of brain glutathione by L-buthionine sulfoximine potentiates the dopamine-depleting action of 6-hydroxydopamine in rat striatum. J Neurochem. 1989;52:978-980.
-
(1989)
J Neurochem
, vol.52
, pp. 978-980
-
-
Pileblad, E.1
Magnusson, T.2
Fornstedt, B.3
-
125
-
-
0029949789
-
Glutathione depletion potentiates MPTP and MPP+ toxicity in nigral dopaminergic neurons
-
Wullner U, Loschmann PA, Schulz JB, Schmid A, Dringen R, Eblen F, et al. Glutathione depletion potentiates MPTP and MPP+ toxicity in nigral dopaminergic neurons. Neuroreport. 1996;7:921-923.
-
(1996)
Neuroreport
, vol.7
, pp. 921-923
-
-
Wullner, U.1
Loschmann, P.A.2
Schulz, J.B.3
Schmid, A.4
Dringen, R.5
Eblen, F.6
-
126
-
-
38349014710
-
Induction of the phase II detoxification pathway suppresses neuron loss in Drosophila models of Parkinson's disease
-
Trinh K, Moore K, Wes PD, Muchowski PJ, Dey J, Andrews L, et al. Induction of the phase II detoxification pathway suppresses neuron loss in Drosophila models of Parkinson's disease. J Neurosci. 2008;28:465-472.
-
(2008)
J Neurosci
, vol.28
, pp. 465-472
-
-
Trinh, K.1
Moore, K.2
Wes, P.D.3
Muchowski, P.J.4
Dey, J.5
Andrews, L.6
-
127
-
-
0032145886
-
Glutamate transporters are oxidant-vulnerable: A molecular link between oxidative and excitotoxic neurodegeneration?
-
Trotti D, Danbolt NC, Volterra A. Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration? Trends Pharmacol Sci. 1998;19:328-334.
-
(1998)
Trends Pharmacol Sci
, vol.19
, pp. 328-334
-
-
Trotti, D.1
Danbolt, N.C.2
Volterra, A.3
-
128
-
-
0034058324
-
Glutamate transport and metabolism in dopaminergic neurons of substantia nigra: Implications for the pathogenesis of Parkinson's disease
-
Plaitakis A, Shashidharan P. Glutamate transport and metabolism in dopaminergic neurons of substantia nigra: implications for the pathogenesis of Parkinson's disease. J Neurol. 2000;247 Suppl 2:II25-II35.
-
(2000)
J Neurol
, vol.247
, Issue.SUPPL. 2
-
-
Plaitakis, A.1
Shashidharan, P.2
-
129
-
-
56649094971
-
-
Berman AE, Chan WY, Brennan AM, Swanson RA. Age-dependent dopaminergic cell loss and nitration of α-synuclein in the substantia nigra of EAAC1-/- mice. Soc Neurosci Abstr. 2007;33:370.3.
-
Berman AE, Chan WY, Brennan AM, Swanson RA. Age-dependent dopaminergic cell loss and nitration of α-synuclein in the substantia nigra of EAAC1-/- mice. Soc Neurosci Abstr. 2007;33:370.3.
-
-
-
-
130
-
-
0035214256
-
Neurochemical findings in the MPTP model of Parkinson's disease
-
Schmidt N, Ferger B. Neurochemical findings in the MPTP model of Parkinson's disease. J Neural Transm. 2001;108:1263-1282.
-
(2001)
J Neural Transm
, vol.108
, pp. 1263-1282
-
-
Schmidt, N.1
Ferger, B.2
-
131
-
-
42449085018
-
Activities of 7-nitroindazole and 1-(2-(trifluoromethylphenyl)-imidazole independent of neuronal nitric-oxide synthase inhibition
-
Matsumura N, Kikuchi-Utsumi K, Nakaki T. Activities of 7-nitroindazole and 1-(2-(trifluoromethylphenyl)-imidazole independent of neuronal nitric-oxide synthase inhibition. J Pharmacol Exp Ther. 2008;325:357-362.
-
(2008)
J Pharmacol Exp Ther
, vol.325
, pp. 357-362
-
-
Matsumura, N.1
Kikuchi-Utsumi, K.2
Nakaki, T.3
-
132
-
-
0029984860
-
-
Przedborski S, Jackson-Lewis V, Yokoyama R, Shibata T, Dawson VL, Dawson TM. Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity. Proc Natl Acad Sci U S A. 1996;93:4565-4571.
-
Przedborski S, Jackson-Lewis V, Yokoyama R, Shibata T, Dawson VL, Dawson TM. Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity. Proc Natl Acad Sci U S A. 1996;93:4565-4571.
-
-
-
-
133
-
-
0030690557
-
Differential modulation of the uptake currents by redox interconversion of cysteine residues in the human neuronal glutamate transporter EAAC1
-
Trotti D, Nussberger S, Volterra A, Hediger MA. Differential modulation of the uptake currents by redox interconversion of cysteine residues in the human neuronal glutamate transporter EAAC1. Eur J Neurosci. 1997;9:2207-2212.
-
(1997)
Eur J Neurosci
, vol.9
, pp. 2207-2212
-
-
Trotti, D.1
Nussberger, S.2
Volterra, A.3
Hediger, M.A.4
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