High-field proton magnetic resonance spectroscopy reveals metabolic effects of normal brain aging

Neurobiology of Aging

Volumn 35, Issue 7, 2014, Pages 1686-1694

  Harris, Janna L ^a,b   Yeh, Hung Wen ^b   Swerdlow, Russell H ^b   Choi, In Young ^a,b   Lee, Phil ^a,b   Brooks, William M ^a,b  

^a UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Bioenergetics; Biomarker; Inflammation; Invivo; Magnetic resonance imaging; Membrane turnover; Neurochemical profile; Oxidative stress; Proton magnetic resonance spectroscopy

Indexed keywords

4 AMINOBUTYRIC ACID; ALANINE; ASCORBIC ACID; ASPARTIC ACID; BIOLOGICAL MARKER; CHOLINE; CREATINE; CREATINE PHOSPHATE; GLUCOSE; GLUTAMIC ACID; GLUTAMINE; GLUTATHIONE; GLYCEROPHOSPHORYLCHOLINE; INOSITOL; LACTIC ACID; N ACETYLASPARTIC ACID; N ACETYLASPARTYLGLUTAMIC ACID; PHOSPHOETHANOLAMINE; PHOSPHORYLCHOLINE; SERINE; TAURINE;

ADULT; AGED; AGING; ANIMAL EXPERIMENT; ARTICLE; BIOENERGY; BRAIN METABOLISM; CELL FUNCTION; CELL MEMBRANE TURNOVER; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; COGNITION; HIPPOCAMPUS; IN VIVO STUDY; INFLAMMATION; MACROMOLECULE; MALE; NEUROCHEMISTRY; NEUROPATHOLOGY; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SENSORIMOTOR CORTEX; TURNOVER TIME; YOUNG ADULT;

AGING; BIOENERGETICS; BIOMARKER; INFLAMMATION; IN VIVO; MAGNETIC RESONANCE IMAGING; MEMBRANE TURNOVER; NEUROCHEMICAL PROFILE; OXIDATIVE STRESS; PROTON MAGNETIC RESONANCE SPECTROSCOPY;

AGING; ANIMALS; ASPARTIC ACID; BRAIN; CHOLINE; FUNCTIONAL NEUROIMAGING; GLUCOSE; GLUTAMIC ACID; MAGNETIC RESONANCE SPECTROSCOPY; MALE; NEUROCHEMISTRY; PROTONS; RATS; RATS, INBRED F344;

EID: 84903363379     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2014.01.018     Document Type: Article

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