Manganese-containing superoxide dismutase signal sequence polymorphism associated with sporadic motor neuron disease

European Journal of Neurology

Volumn 6, Issue 6, 1999, Pages 639-644

  Andersen, Peter Munch ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Amyotrophic lateral sclerosis; Manganese containing superoxide dismutase; Mitochondria; Motor neuron disease; Oxidative stress; Signal sequence

Indexed keywords

ALANINE; MANGANESE SUPEROXIDE DISMUTASE; MITOCHONDRIAL ENZYME; SIGNAL PEPTIDE; VALINE;

ALLELE; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CONTROLLED STUDY; FEMALE; GENE MUTATION; GENE TARGETING; GENETIC POLYMORPHISM; GENOTYPE; HOMOZYGOSITY; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; MOTOR NEURON DISEASE; OLIGONUCLEOTIDE PROBE; PRIORITY JOURNAL; RISK FACTOR; SWEDEN;

EID: 0032779847     PISSN: 13515101     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1468-1331.1999.660639.x     Document Type: Article

References (3)

1. Andersen PM, Nilsson P, Keränen M-L, Forsgren L, Hägglund J, Karlsborg M, et al. (1997). Phenotypic heterogeneity in motor neuron disease patients with CuZn-superoxide dismutase mutations in Scandinavia. Brain 120:1723-1737.
2. Beal MF, Ferrante RJ, Browne SE, Matthews RT, Kowall NW, Brown RH (1997). Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis. Ann Neurol 42:646-654.
3. Beckman JS, Larson M, Smith CE, Koppenol WH (1993) [Commentary]. ALS, SOD and peroxynitrite. Nature 364:584.