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Volumn 179, Issue 3, 2015, Pages 363-377

Immune homeostasis, dysbiosis and therapeutic modulation of the gut microbiota

Author keywords

Bacterial; Host pathogen interactions; Inflammation; Mucosa

Indexed keywords

PROBIOTIC AGENT;

EID: 84922805709     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/cei.12474     Document Type: Review
Times cited : (232)

References (146)
  • 1
    • 20544444045 scopus 로고    scopus 로고
    • Diversity of the human intestinal microbial flora
    • Eckburg PB, Bik EM, Bernstein CN etal. Diversity of the human intestinal microbial flora. Science 2005; 308:1635-1638. doi: 10.1126/science.1110591.
    • (2005) Science , vol.308 , pp. 1635-1638
    • Eckburg, P.B.1    Bik, E.M.2    Bernstein, C.N.3
  • 2
    • 33845508443 scopus 로고    scopus 로고
    • Genomic and metabolic studies of the impact of probiotics on a model gut symbiont and host
    • Sonnenburg JL, Chen CT, Gordon JI. Genomic and metabolic studies of the impact of probiotics on a model gut symbiont and host. PLOS Biol 2006; 4:e413. doi: 10.1371/journal.pbio.0040413.
    • (2006) PLOS Biol , vol.4 , pp. e413
    • Sonnenburg, J.L.1    Chen, C.T.2    Gordon, J.I.3
  • 3
    • 33745610880 scopus 로고    scopus 로고
    • A humanized gnotobiotic mouse model of host-archaeal-bacterial mutualism
    • Samuel BS, Gordon JI. A humanized gnotobiotic mouse model of host-archaeal-bacterial mutualism. Proc Natl Acad Sci USA 2006; 103:10011-10016. doi: 10.1073/pnas.0602187103.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 10011-10016
    • Samuel, B.S.1    Gordon, J.I.2
  • 4
    • 33645051439 scopus 로고    scopus 로고
    • H2 and acetate transfers during xylan fermentation between a butyrate-producing xylanolytic species and hydrogenotrophic microorganisms from the human gut
    • Chassard C, Bernalier-Donadille A. H2 and acetate transfers during xylan fermentation between a butyrate-producing xylanolytic species and hydrogenotrophic microorganisms from the human gut. FEMS Microbiol Lett 2006; 254:116-122. doi: 10.1111/j.1574-6968.2005.00016.x.
    • (2006) FEMS Microbiol Lett , vol.254 , pp. 116-122
    • Chassard, C.1    Bernalier-Donadille, A.2
  • 6
    • 65249149643 scopus 로고    scopus 로고
    • Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla
    • Mahowald MA, Rey FE, Seedorf H etal. Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla. Proc Natl Acad Sci USA 2009; 106:5859-5864. doi: 10.1073/pnas.0901529106.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 5859-5864
    • Mahowald, M.A.1    Rey, F.E.2    Seedorf, H.3
  • 7
    • 80054925355 scopus 로고    scopus 로고
    • Eating for two: how metabolism establishes interspecies interactions in the gut
    • Fischbach MA, Sonnenburg JL. Eating for two: how metabolism establishes interspecies interactions in the gut. Cell Host Microbe 2011; 10:336-347. doi: 10.1016/j.chom.2011.10.002.
    • (2011) Cell Host Microbe , vol.10 , pp. 336-347
    • Fischbach, M.A.1    Sonnenburg, J.L.2
  • 8
    • 77950251400 scopus 로고    scopus 로고
    • A human gut microbial gene catalogue established by metagenomic sequencing
    • Qin J, Li R, Raes J etal. A human gut microbial gene catalogue established by metagenomic sequencing. Nature 2010; 464:59-65. doi: 10.1038/nature08821.
    • (2010) Nature , vol.464 , pp. 59-65
    • Qin, J.1    Li, R.2    Raes, J.3
  • 9
    • 54549122338 scopus 로고    scopus 로고
    • Innate immunity and intestinal microbiota in the development of Type 1 diabetes
    • Wen L, Ley RE, Volchkov PY etal. Innate immunity and intestinal microbiota in the development of Type 1 diabetes. Nature 2008; 455:1109-1113. doi: 10.1038/nature07336.
    • (2008) Nature , vol.455 , pp. 1109-1113
    • Wen, L.1    Ley, R.E.2    Volchkov, P.Y.3
  • 10
    • 78449296237 scopus 로고    scopus 로고
    • Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors
    • Benson AK, Kelly SA, Legge R etal. Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors. Proc Natl Acad Sci USA 2010; 107:18933-18938. doi: 10.1073/pnas.1007028107.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 18933-18938
    • Benson, A.K.1    Kelly, S.A.2    Legge, R.3
  • 11
    • 84866146940 scopus 로고    scopus 로고
    • Diversity, stability and resilience of the human gut microbiota
    • Lozupone CA, Stombaugh JI, Gordon JI, Jansson JK, Knight R. Diversity, stability and resilience of the human gut microbiota. Nature 2012; 489:220-230. doi: 10.1038/nature11550.
    • (2012) Nature , vol.489 , pp. 220-230
    • Lozupone, C.A.1    Stombaugh, J.I.2    Gordon, J.I.3    Jansson, J.K.4    Knight, R.5
  • 12
    • 77950669604 scopus 로고    scopus 로고
    • The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice
    • Turnbaugh PJ, Ridaura VK, Faith JJ, Rey FE, Knight R, Gordon JI. The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice. Sci Transl Med 2009; 1:6ra14. doi: 10.1126/scitranslmed.3000322.
    • (2009) Sci Transl Med , vol.1 , pp. 6ra14
    • Turnbaugh, P.J.1    Ridaura, V.K.2    Faith, J.J.3    Rey, F.E.4    Knight, R.5    Gordon, J.I.6
  • 13
    • 58749112734 scopus 로고    scopus 로고
    • A core gut microbiome in obese and lean twins
    • Turnbaugh PJ, Hamady M, Yatsunenko T etal. A core gut microbiome in obese and lean twins. Nature 2009; 457:480-484. doi: 10.1038/nature07540.
    • (2009) Nature , vol.457 , pp. 480-484
    • Turnbaugh, P.J.1    Hamady, M.2    Yatsunenko, T.3
  • 14
    • 84862141704 scopus 로고    scopus 로고
    • Human gut microbiome viewed across age and geography
    • Yatsunenko T, Rey FE, Manary MJ etal. Human gut microbiome viewed across age and geography. Nature 2012; 486:222-227. doi: 10.1038/nature11053.
    • (2012) Nature , vol.486 , pp. 222-227
    • Yatsunenko, T.1    Rey, F.E.2    Manary, M.J.3
  • 15
    • 79955783588 scopus 로고    scopus 로고
    • Determinants of the human infant intestinal microbiota after the introduction of first complementary foods in infant samples from five European centres
    • Fallani M, Amarri S, Uusijarvi A etal. Determinants of the human infant intestinal microbiota after the introduction of first complementary foods in infant samples from five European centres. Microbiology 2011; 157:1385-1392. doi: 10.1099/mic.0.042143-0.
    • (2011) Microbiology , vol.157 , pp. 1385-1392
    • Fallani, M.1    Amarri, S.2    Uusijarvi, A.3
  • 16
    • 79952756960 scopus 로고    scopus 로고
    • Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation
    • Dethlefsen L, Relman DA. Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation. Proc Natl Acad Sci USA 2011; 108 (Suppl. 1):4554-4561. doi: 1073/pnas.1000087107.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 4554-4561
    • Dethlefsen, L.1    Relman, D.A.2
  • 17
    • 0025582034 scopus 로고
    • The CNS and collaborative practice
    • Mills ME. The CNS and collaborative practice. Clin Nurse Spec 1990; 4:194-195.
    • (1990) Clin Nurse Spec , vol.4 , pp. 194-195
    • Mills, M.E.1
  • 18
    • 84864722033 scopus 로고    scopus 로고
    • Gut microbiota composition correlates with diet and health in the elderly
    • Claesson MJ, Jeffery IB, Conde S etal. Gut microbiota composition correlates with diet and health in the elderly. Nature 2012; 488:178-184. doi: 10.1038/nature11319.
    • (2012) Nature , vol.488 , pp. 178-184
    • Claesson, M.J.1    Jeffery, I.B.2    Conde, S.3
  • 19
    • 84858596184 scopus 로고    scopus 로고
    • Effect of prebiotics on the human gut microbiota of elderly persons
    • Toward R, Montandon S, Walton G, Gibson GR. Effect of prebiotics on the human gut microbiota of elderly persons. Gut Microbes 2012; 3:57-60. doi: 10.4161/gmic.19411.
    • (2012) Gut Microbes , vol.3 , pp. 57-60
    • Toward, R.1    Montandon, S.2    Walton, G.3    Gibson, G.R.4
  • 20
    • 84874172336 scopus 로고    scopus 로고
    • Healthy effects exerted by prebiotics, probiotics, and symbiotics with special reference to their impact on the immune system
    • Jirillo E, Jirillo F, Magrone T. Healthy effects exerted by prebiotics, probiotics, and symbiotics with special reference to their impact on the immune system. Int J Vitam Nutr Res 2012; 82:200-208. doi: 10.1024/0300-9831/a000112.
    • (2012) Int J Vitam Nutr Res , vol.82 , pp. 200-208
    • Jirillo, E.1    Jirillo, F.2    Magrone, T.3
  • 21
    • 33144460422 scopus 로고    scopus 로고
    • Differences in fecal microbiota in different European study populations in relation to age, gender, and country: a cross-sectional study
    • Mueller S, Saunier K, Hanisch C etal. Differences in fecal microbiota in different European study populations in relation to age, gender, and country: a cross-sectional study. Appl Environ Microbiol 2006; 72:1027-1033. doi: 10.1128/AEM.72.2.1027-1033.2006.
    • (2006) Appl Environ Microbiol , vol.72 , pp. 1027-1033
    • Mueller, S.1    Saunier, K.2    Hanisch, C.3
  • 22
    • 84867212865 scopus 로고    scopus 로고
    • Gut microbiota: dietary and social modulation of gut microbiota in the elderly
    • Kinross J, Nicholson JK. Gut microbiota: dietary and social modulation of gut microbiota in the elderly. Nat Rev Gastroenterol Hepatol 2012; 9:563-564. doi: 10.1038/nrgastro.2012.169.
    • (2012) Nat Rev Gastroenterol Hepatol , vol.9 , pp. 563-564
    • Kinross, J.1    Nicholson, J.K.2
  • 23
    • 79952757721 scopus 로고    scopus 로고
    • Composition, variability, and temporal stability of the intestinal microbiota of the elderly
    • Claesson MJ, Cusack S, O'Sullivan O etal. Composition, variability, and temporal stability of the intestinal microbiota of the elderly. Proc Natl Acad Sci USA 2011; 108 (Suppl. 1):4586-4591. doi: 10.1073/pnas.1000097107.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 4586-4591
    • Claesson, M.J.1    Cusack, S.2    O'Sullivan, O.3
  • 24
    • 84874766374 scopus 로고    scopus 로고
    • Identification of intracellular bacteria in the basal plate of the human placenta in term and preterm gestations
    • 226e1-22267
    • Stout MJ, Conlon B, Landeau M etal. Identification of intracellular bacteria in the basal plate of the human placenta in term and preterm gestations. Am J Obstet Gynecol 2013; 208:226.e1-2267. doi: 10.1016/j.ajog.2013.01.018.
    • (2013) Am J Obstet Gynecol , vol.208
    • Stout, M.J.1    Conlon, B.2    Landeau, M.3
  • 25
    • 41949094718 scopus 로고    scopus 로고
    • Is meconium from healthy newborns actually sterile?
    • Jimenez E, Marin ML, Martin R etal. Is meconium from healthy newborns actually sterile? Res Microbiol 2008; 159:187-193. doi: 10.1016/j.resmic.2007.12.007.
    • (2008) Res Microbiol , vol.159 , pp. 187-193
    • Jimenez, E.1    Marin, M.L.2    Martin, R.3
  • 26
    • 84907165154 scopus 로고    scopus 로고
    • Acquiring and maintaining a normal oral microbiome: current perspective
    • Zaura E, Nicu EA, Krom BP, Keijser BJ. Acquiring and maintaining a normal oral microbiome: current perspective. Front Cell Infect Microbiol 2014; 4:851-858. doi: 10.3389/fcimb.2014.00085.
    • (2014) Front Cell Infect Microbiol , vol.4 , pp. 851-858
    • Zaura, E.1    Nicu, E.A.2    Krom, B.P.3    Keijser, B.J.4
  • 27
    • 33646076440 scopus 로고    scopus 로고
    • Effect of maternal consumption of lactobacillus GG on transfer and establishment of fecal bifidobacterial microbiota in neonates
    • Gueimonde M, Sakata S, Kalliomaki M, Isolauri E, Benno Y, Salminen S. Effect of maternal consumption of lactobacillus GG on transfer and establishment of fecal bifidobacterial microbiota in neonates. J Pediatr Gastroenterol Nutr 2006; 42:166-170. doi: 10.1097/01.mpg.0000189346.25172.fd.
    • (2006) J Pediatr Gastroenterol Nutr , vol.42 , pp. 166-170
    • Gueimonde, M.1    Sakata, S.2    Kalliomaki, M.3    Isolauri, E.4    Benno, Y.5    Salminen, S.6
  • 29
    • 33748415364 scopus 로고    scopus 로고
    • Factors influencing the composition of the intestinal microbiota in early infancy
    • Penders J, Thijs C, Vink C etal. Factors influencing the composition of the intestinal microbiota in early infancy. Pediatrics 2006; 118:511-521. doi: 10.1542/peds.2005-2824.
    • (2006) Pediatrics , vol.118 , pp. 511-521
    • Penders, J.1    Thijs, C.2    Vink, C.3
  • 30
    • 77955386857 scopus 로고    scopus 로고
    • Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns
    • Dominguez-Bello MG, Costello EK, Contreras M etal. Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns. Proc Natl Acad Sci USA 2010; 107:11971-11975. doi: 10.1073/pnas.1002601107.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 11971-11975
    • Dominguez-Bello, M.G.1    Costello, E.K.2    Contreras, M.3
  • 32
    • 78650847143 scopus 로고    scopus 로고
    • Mode of delivery affects the bacterial community in the newborn gut
    • Biasucci G, Rubini M, Riboni S, Morelli L, Bessi E, Retetangos C. Mode of delivery affects the bacterial community in the newborn gut. Early Hum Dev 2010; 86 (Suppl. 1):13-15. doi: 10.1016/j.earlhumdev.2010.01.004.
    • (2010) Early Hum Dev , vol.86 , pp. 13-15
    • Biasucci, G.1    Rubini, M.2    Riboni, S.3    Morelli, L.4    Bessi, E.5    Retetangos, C.6
  • 34
    • 34547129847 scopus 로고    scopus 로고
    • Development of the human infant intestinal microbiota
    • Palmer C, Bik EM, DiGiulio DB, Relman DA, Brown PO. Development of the human infant intestinal microbiota. PLOS Biol 2007; 5:e177. doi: 10.1371/journal.pbio.0050177.
    • (2007) PLOS Biol , vol.5 , pp. e177
    • Palmer, C.1    Bik, E.M.2    DiGiulio, D.B.3    Relman, D.A.4    Brown, P.O.5
  • 35
    • 79551622954 scopus 로고    scopus 로고
    • Strain-resolved community genomic analysis of gut microbial colonization in a premature infant
    • Morowitz MJ, Denef VJ, Costello EK etal. Strain-resolved community genomic analysis of gut microbial colonization in a premature infant. Proc Natl Acad Sci USA 2011; 108:1128-1133. doi: 10.1073/pnas.1010992108.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 1128-1133
    • Morowitz, M.J.1    Denef, V.J.2    Costello, E.K.3
  • 36
    • 79952763661 scopus 로고    scopus 로고
    • Succession of microbial consortia in the developing infant gut microbiome
    • Koenig JE, Spor A, Scalfone N etal. Succession of microbial consortia in the developing infant gut microbiome. Proc Natl Acad Sci USA 2011; 108 (Suppl. 1):4578-4585. doi: 10.1073/pnas.1000081107.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 4578-4585
    • Koenig, J.E.1    Spor, A.2    Scalfone, N.3
  • 37
    • 84864579031 scopus 로고    scopus 로고
    • Microbial co-occurrence relationships in the human microbiome
    • Faust K, Sathirapongsasuti JF, Izard J etal. Microbial co-occurrence relationships in the human microbiome. PLOS Comput Biol 2012; 8:e1002606. doi: 10.1371/journal.pcbi.1002606.
    • (2012) PLOS Comput Biol , vol.8 , pp. e1002606
    • Faust, K.1    Sathirapongsasuti, J.F.2    Izard, J.3
  • 38
    • 84863920287 scopus 로고    scopus 로고
    • Microbial interactions: from networks to models
    • Faust K, Raes J. Microbial interactions: from networks to models. Nat Rev Microbiol 2012; 10:538-550. doi: 10.1038/nrmicro2832.
    • (2012) Nat Rev Microbiol , vol.10 , pp. 538-550
    • Faust, K.1    Raes, J.2
  • 39
    • 8144226856 scopus 로고    scopus 로고
    • The gut microbiota as an environmental factor that regulates fat storage
    • Backhed F, Ding H, Wang T etal. The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci USA 2004; 101:15718-15723.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 15718-15723
    • Backhed, F.1    Ding, H.2    Wang, T.3
  • 40
    • 84864756231 scopus 로고    scopus 로고
    • The human microbiome: ecosystem resilience and health
    • Relman DA. The human microbiome: ecosystem resilience and health. Nutr Rev 2012; 70 (Suppl. 1):S2-9. doi: 10.1111/j.1753-4887.2012.00489.x.
    • (2012) Nutr Rev , vol.70 , pp. S2-S9
    • Relman, D.A.1
  • 41
    • 84863718303 scopus 로고    scopus 로고
    • Analysis of gut microbial regulation of host gene expression along the length of the gut and regulation of gut microbial ecology through MyD88
    • Larsson E, Tremaroli V, Lee YS etal. Analysis of gut microbial regulation of host gene expression along the length of the gut and regulation of gut microbial ecology through MyD88. Gut 2012; 61:1124-1131. doi: 10.1136/gutjnl-2011-301104.
    • (2012) Gut , vol.61 , pp. 1124-1131
    • Larsson, E.1    Tremaroli, V.2    Lee, Y.S.3
  • 42
    • 0035524488 scopus 로고    scopus 로고
    • Toll-like receptors and innate immunity
    • Medzhitov R. Toll-like receptors and innate immunity. Nat Rev Immunol 2001; 1:135-145. doi: 10.1038/35100529.
    • (2001) Nat Rev Immunol , vol.1 , pp. 135-145
    • Medzhitov, R.1
  • 43
    • 33846150625 scopus 로고    scopus 로고
    • TLRs in the Gut I. The role of TLRs/NODs in intestinal development and homeostasis
    • Sanderson IR, Walker WA. TLRs in the Gut I. The role of TLRs/NODs in intestinal development and homeostasis. Am J Physiol Gastrointest Liver Physiol 2007; 292:G6-10. doi: 10.1152/ajpgi.00275.2006.
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292 , pp. G6-10
    • Sanderson, I.R.1    Walker, W.A.2
  • 44
    • 68049093204 scopus 로고    scopus 로고
    • Learning tolerance while fighting ignorance
    • Sansonetti PJ, Medzhitov R. Learning tolerance while fighting ignorance. Cell 2009; 138:416-420. doi: 10.1016/j.cell.2009.07.024.
    • (2009) Cell , vol.138 , pp. 416-420
    • Sansonetti, P.J.1    Medzhitov, R.2
  • 45
    • 77649086402 scopus 로고    scopus 로고
    • Immune adaptations that maintain homeostasis with the intestinal microbiota
    • Hooper LV, Macpherson AJ. Immune adaptations that maintain homeostasis with the intestinal microbiota. Nat Rev Immunol 2010; 10:159-169. doi: 10.1038/nri2710.
    • (2010) Nat Rev Immunol , vol.10 , pp. 159-169
    • Hooper, L.V.1    Macpherson, A.J.2
  • 46
    • 13244292161 scopus 로고    scopus 로고
    • Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
    • Kobayashi KS, Chamaillard M, Ogura Y etal. Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science 2005; 307:731-734. doi: 10.1126/science.1104911.
    • (2005) Science , vol.307 , pp. 731-734
    • Kobayashi, K.S.1    Chamaillard, M.2    Ogura, Y.3
  • 47
    • 84864322646 scopus 로고    scopus 로고
    • Priming of natural killer cells by nonmucosal mononuclear phagocytes requires instructive signals from commensal microbiota
    • Ganal SC, Sanos SL, Kallfass C etal. Priming of natural killer cells by nonmucosal mononuclear phagocytes requires instructive signals from commensal microbiota. Immunity 2012; 37:171-186. doi: 10.1016/j.immuni.2012.05.020.
    • (2012) Immunity , vol.37 , pp. 171-186
    • Ganal, S.C.1    Sanos, S.L.2    Kallfass, C.3
  • 48
    • 33746377279 scopus 로고    scopus 로고
    • Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation
    • Izcue A, Coombes JL, Powrie F. Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation. Immunol Rev 2006; 212:256-271. doi: 10.1111/j.0105-2896.2006.00423.x.
    • (2006) Immunol Rev , vol.212 , pp. 256-271
    • Izcue, A.1    Coombes, J.L.2    Powrie, F.3
  • 49
    • 84877742439 scopus 로고    scopus 로고
    • Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota
    • Cebula A, Seweryn M, Rempala GA etal. Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota. Nature 2013; 497:258-262. doi: 10.1038/nature12079.
    • (2013) Nature , vol.497 , pp. 258-262
    • Cebula, A.1    Seweryn, M.2    Rempala, G.A.3
  • 50
    • 25444518195 scopus 로고    scopus 로고
    • Cutting edge: bacterial modulation of epithelial signaling via changes in neddylation of cullin-1
    • Collier-Hyams LS, Sloane V, Batten BC, Neish AS. Cutting edge: bacterial modulation of epithelial signaling via changes in neddylation of cullin-1. J Immunol 2005; 175:4194-4198.
    • (2005) J Immunol , vol.175 , pp. 4194-4198
    • Collier-Hyams, L.S.1    Sloane, V.2    Batten, B.C.3    Neish, A.S.4
  • 51
    • 0347756655 scopus 로고    scopus 로고
    • Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-gamma and RelA
    • Kelly D, Campbell JI, King TP etal. Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-gamma and RelA. Nat Immunol 2004; 5:104-112. doi: 10.1038/ni1018.
    • (2004) Nat Immunol , vol.5 , pp. 104-112
    • Kelly, D.1    Campbell, J.I.2    King, T.P.3
  • 52
    • 30744462290 scopus 로고    scopus 로고
    • Anti-inflammatory effect of Lactobacillus casei on Shigella-infected human intestinal epithelial cells
    • Tien MT, Girardin SE, Regnault B etal. Anti-inflammatory effect of Lactobacillus casei on Shigella-infected human intestinal epithelial cells. J Immunol 2006; 176:1228-1237.
    • (2006) J Immunol , vol.176 , pp. 1228-1237
    • Tien, M.T.1    Girardin, S.E.2    Regnault, B.3
  • 53
    • 44449106055 scopus 로고    scopus 로고
    • A microbial symbiosis factor prevents intestinal inflammatory disease
    • Mazmanian SK, Round JL, Kasper DL. A microbial symbiosis factor prevents intestinal inflammatory disease. Nature 2008; 453:620-625. doi: 10.1038/nature07008.
    • (2008) Nature , vol.453 , pp. 620-625
    • Mazmanian, S.K.1    Round, J.L.2    Kasper, D.L.3
  • 54
    • 85027947787 scopus 로고    scopus 로고
    • Induction of colonic regulatory T cells by indigenous Clostridium species
    • Atarashi K, Tanoue T, Shima T etal. Induction of colonic regulatory T cells by indigenous Clostridium species. Science 2011; 331:337-341. doi: 10.1126/science.1198469.
    • (2011) Science , vol.331 , pp. 337-341
    • Atarashi, K.1    Tanoue, T.2    Shima, T.3
  • 55
    • 53649100675 scopus 로고    scopus 로고
    • ATP drives lamina propria T(H)17 cell differentiation
    • Atarashi K, Nishimura J, Shima T etal. ATP drives lamina propria T(H)17 cell differentiation. Nature 2008; 455:808-812. doi: 10.1038/nature07240.
    • (2008) Nature , vol.455 , pp. 808-812
    • Atarashi, K.1    Nishimura, J.2    Shima, T.3
  • 56
    • 70350343544 scopus 로고    scopus 로고
    • Induction of intestinal Th17 cells by segmented filamentous bacteria
    • Ivanov II, Atarashi K, Manel N etal. Induction of intestinal Th17 cells by segmented filamentous bacteria. Cell 2009; 139:485-498. doi: 10.1016/j.cell.2009.09.033.
    • (2009) Cell , vol.139 , pp. 485-498
    • Ivanov, I.I.1    Atarashi, K.2    Manel, N.3
  • 57
    • 77954738601 scopus 로고    scopus 로고
    • Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota
    • Round JL, Mazmanian SK. Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota. Proc Natl Acad Sci USA 2010; 107:12204-12209. doi: 10.1073/pnas.0909122107.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 12204-12209
    • Round, J.L.1    Mazmanian, S.K.2
  • 58
    • 27744580095 scopus 로고    scopus 로고
    • Resilience of the dominant human fecal microbiota upon short-course antibiotic challenge
    • De La Cochetiere MF, Durand T, Lepage P, Bourreille A, Galmiche JP, Dore J. Resilience of the dominant human fecal microbiota upon short-course antibiotic challenge. J Clin Microbiol 2005; 43:5588-5592. doi: 10.1128/JCM.43.11.5588-5592.2005.
    • (2005) J Clin Microbiol , vol.43 , pp. 5588-5592
    • De La Cochetiere, M.F.1    Durand, T.2    Lepage, P.3    Bourreille, A.4    Galmiche, J.P.5    Dore, J.6
  • 59
    • 84899145858 scopus 로고    scopus 로고
    • Effect of various antibiotics on modulation of intestinal microbiota and bile acid profile in mice
    • Zhang Y, Limaye PB, Renaud HJ, Klaassen CD. Effect of various antibiotics on modulation of intestinal microbiota and bile acid profile in mice. Toxicol Appl Pharmacol 2014; 277:138-145. doi: 10.1016/j.taap.2014.03.009.
    • (2014) Toxicol Appl Pharmacol , vol.277 , pp. 138-145
    • Zhang, Y.1    Limaye, P.B.2    Renaud, H.J.3    Klaassen, C.D.4
  • 60
    • 1542513850 scopus 로고    scopus 로고
    • Antibiotic-associated diarrhea accompanied by large-scale alterations in the composition of the fecal microbiota
    • Young VB, Schmidt TM. Antibiotic-associated diarrhea accompanied by large-scale alterations in the composition of the fecal microbiota. J Clin Microbiol 2004; 42:1203-1206.
    • (2004) J Clin Microbiol , vol.42 , pp. 1203-1206
    • Young, V.B.1    Schmidt, T.M.2
  • 61
    • 66549102207 scopus 로고    scopus 로고
    • Reproducible community dynamics of the gastrointestinal microbiota following antibiotic perturbation
    • Antonopoulos DA, Huse SM, Morrison HG, Schmidt TM, Sogin ML, Young VB. Reproducible community dynamics of the gastrointestinal microbiota following antibiotic perturbation. Infect Immun 2009; 77:2367-2375. doi: 10.1128/IAI.01520-08.
    • (2009) Infect Immun , vol.77 , pp. 2367-2375
    • Antonopoulos, D.A.1    Huse, S.M.2    Morrison, H.G.3    Schmidt, T.M.4    Sogin, M.L.5    Young, V.B.6
  • 62
    • 56849106496 scopus 로고    scopus 로고
    • The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing
    • Dethlefsen L, Huse S, Sogin ML, Relman DA. The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing. PLOS Biol 2008; 6:e280. doi: 10.1371/journal.pbio.0060280.
    • (2008) PLOS Biol , vol.6 , pp. e280
    • Dethlefsen, L.1    Huse, S.2    Sogin, M.L.3    Relman, D.A.4
  • 63
    • 84898662818 scopus 로고    scopus 로고
    • Alteration of the murine gastrointestinal microbiota by tigecycline leads to increased susceptibility to Clostridium difficile infection
    • Bassis CM, Theriot CM, Young VB. Alteration of the murine gastrointestinal microbiota by tigecycline leads to increased susceptibility to Clostridium difficile infection. Antimicrob Agents Chemother 2014; 58:2767-2774. doi: 10.1128/AAC.02262-13.
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 2767-2774
    • Bassis, C.M.1    Theriot, C.M.2    Young, V.B.3
  • 64
    • 78049522796 scopus 로고    scopus 로고
    • Long-term impacts of antibiotic exposure on the human intestinal microbiota
    • Jernberg C, Lofmark S, Edlund C, Jansson JK. Long-term impacts of antibiotic exposure on the human intestinal microbiota. Microbiology 2010; 156:3216-3223. doi: 10.1099/mic.0.040618-0.
    • (2010) Microbiology , vol.156 , pp. 3216-3223
    • Jernberg, C.1    Lofmark, S.2    Edlund, C.3    Jansson, J.K.4
  • 65
    • 75749110963 scopus 로고    scopus 로고
    • Metronidazole is still the drug of choice for treatment of anaerobic infections
    • Lofmark S, Edlund C, Nord CE. Metronidazole is still the drug of choice for treatment of anaerobic infections. Clin Infect Dis 2010; 50 (Suppl. 1):S16-23. doi: 10.1086/647939.
    • (2010) Clin Infect Dis , vol.50 , pp. S16-S23
    • Lofmark, S.1    Edlund, C.2    Nord, C.E.3
  • 66
    • 84874594680 scopus 로고    scopus 로고
    • Crystal structure, antibacterial and cytotoxic activities of a new complex of bismuth(III) with sulfapyridine
    • Marzano IM, Franco MS, Silva PP etal. Crystal structure, antibacterial and cytotoxic activities of a new complex of bismuth(III) with sulfapyridine. Molecules 2013; 18:1464-1476. doi: 10.3390/molecules18021464.
    • (2013) Molecules , vol.18 , pp. 1464-1476
    • Marzano, I.M.1    Franco, M.S.2    Silva, P.P.3
  • 67
    • 0038730576 scopus 로고    scopus 로고
    • Use of denaturing gradient gel electrophoresis for analysis of the stool microbiota of hospitalized patients
    • Donskey CJ, Hujer AM, Das SM, Pultz NJ, Bonomo RA, Rice LB. Use of denaturing gradient gel electrophoresis for analysis of the stool microbiota of hospitalized patients. J Microbiol Methods 2003; 54:249-256.
    • (2003) J Microbiol Methods , vol.54 , pp. 249-256
    • Donskey, C.J.1    Hujer, A.M.2    Das, S.M.3    Pultz, N.J.4    Bonomo, R.A.5    Rice, L.B.6
  • 68
    • 44149126798 scopus 로고    scopus 로고
    • Secreted enteric antimicrobial activity localises to the mucus surface layer
    • Meyer-Hoffert U, Hornef MW, Henriques-Normark B etal. Secreted enteric antimicrobial activity localises to the mucus surface layer. Gut 2008; 57:764-771. doi: 10.1136/gut.2007.141481.
    • (2008) Gut , vol.57 , pp. 764-771
    • Meyer-Hoffert, U.1    Hornef, M.W.2    Henriques-Normark, B.3
  • 69
    • 53649098280 scopus 로고    scopus 로고
    • Vancomycin-resistant enterococci exploit antibiotic- induced innate immune deficits
    • Brandl K, Plitas G, Mihu CN etal. Vancomycin-resistant enterococci exploit antibiotic- induced innate immune deficits. Nature 2008; 455:804-807. doi: 10.1038/nature07250.
    • (2008) Nature , vol.455 , pp. 804-807
    • Brandl, K.1    Plitas, G.2    Mihu, C.N.3
  • 70
    • 66649092877 scopus 로고    scopus 로고
    • Toll-like receptor 2 is critical for induction of Reg3 beta expression and intestinal clearance of Yersinia pseudotuberculosis
    • Dessein R, Gironella M, Vignal C etal. Toll-like receptor 2 is critical for induction of Reg3 beta expression and intestinal clearance of Yersinia pseudotuberculosis. Gut 2009; 58:771-776. doi: 10.1136/gut.2008.168443.
    • (2009) Gut , vol.58 , pp. 771-776
    • Dessein, R.1    Gironella, M.2    Vignal, C.3
  • 71
    • 15044359916 scopus 로고    scopus 로고
    • Effects of a short-course of amoxicillin/clavulanic acid on systemic and mucosal immunity in healthy adult humans
    • Dufour V, Millon L, Faucher JF etal. Effects of a short-course of amoxicillin/clavulanic acid on systemic and mucosal immunity in healthy adult humans. Int Immunopharmacol 2005; 5:917-928. doi: 10.1016/j.intimp.2005.01.007.
    • (2005) Int Immunopharmacol , vol.5 , pp. 917-928
    • Dufour, V.1    Millon, L.2    Faucher, J.F.3
  • 72
    • 33646803903 scopus 로고    scopus 로고
    • Neonatal antibiotic treatment alters gastrointestinal tract developmental gene expression and intestinal barrier transcriptome
    • Schumann A, Nutten S, Donnicola D etal. Neonatal antibiotic treatment alters gastrointestinal tract developmental gene expression and intestinal barrier transcriptome. Physiol Genomics 2005; 23:235-245. doi: 10.1152/physiolgenomics.00057.2005.
    • (2005) Physiol Genomics , vol.23 , pp. 235-245
    • Schumann, A.1    Nutten, S.2    Donnicola, D.3
  • 73
    • 53349173070 scopus 로고    scopus 로고
    • Specific microbiota direct the differentiation of IL-17- producing T-helper cells in the mucosa of the small intestine
    • Ivanov II, Frutos Rde L, Manel N etal. Specific microbiota direct the differentiation of IL-17- producing T-helper cells in the mucosa of the small intestine. Cell Host Microbe 2008; 4:337-349. doi: 10.1016/j.chom.2008.09.009.
    • (2008) Cell Host Microbe , vol.4 , pp. 337-349
    • Ivanov, I.I.1    Frutos Rde, L.2    Manel, N.3
  • 74
    • 77249163771 scopus 로고    scopus 로고
    • Metagenomic analyses reveal antibiotic-induced temporal and spatial changes in intestinal microbiota with associated alterations in immune cell homeostasis
    • Hill DA, Hoffmann C, Abt MC etal. Metagenomic analyses reveal antibiotic-induced temporal and spatial changes in intestinal microbiota with associated alterations in immune cell homeostasis. Mucosal Immunol 2010; 3:148-158. doi: 10.1038/mi.2009.132.
    • (2010) Mucosal Immunol , vol.3 , pp. 148-158
    • Hill, D.A.1    Hoffmann, C.2    Abt, M.C.3
  • 75
    • 78649686679 scopus 로고    scopus 로고
    • A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypes
    • 1844-54e1
    • Willing BP, Dicksved J, Halfvarson J etal. A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypes. Gastroenterology 2010; 139:1844-54.e1. doi: 10.1053/j.gastro.2010.08.049.
    • (2010) Gastroenterology , vol.139
    • Willing, B.P.1    Dicksved, J.2    Halfvarson, J.3
  • 76
    • 84862116034 scopus 로고    scopus 로고
    • Gut bacteria in health and disease: a survey on the interface between intestinal microbiology and colorectal cancer
    • Boleij A, Tjalsma H. Gut bacteria in health and disease: a survey on the interface between intestinal microbiology and colorectal cancer. Biol Rev Camb Phil Soc 2012; 87:701-730. doi: 10.1111/j.1469-185X.2012.00218.x.
    • (2012) Biol Rev Camb Phil Soc , vol.87 , pp. 701-730
    • Boleij, A.1    Tjalsma, H.2
  • 77
    • 10744221150 scopus 로고    scopus 로고
    • Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis
    • Rutter M, Saunders B, Wilkinson K etal. Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis. Gastroenterology 2004; 126:451-459.
    • (2004) Gastroenterology , vol.126 , pp. 451-459
    • Rutter, M.1    Saunders, B.2    Wilkinson, K.3
  • 78
    • 55949124035 scopus 로고    scopus 로고
    • Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
    • Sokol H, Pigneur B, Watterlot L etal. Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc Natl Acad Sci USA 2008; 105:16731-16736. doi: 10.1073/pnas.0804812105.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 16731-16736
    • Sokol, H.1    Pigneur, B.2    Watterlot, L.3
  • 79
    • 84879075084 scopus 로고    scopus 로고
    • Intestinal microbiota: a source of novel biomarkers in inflammatory bowel diseases?
    • Berry D, Reinisch W. Intestinal microbiota: a source of novel biomarkers in inflammatory bowel diseases? Best Pract Res Clin Gastroenterol 2013; 27:47-58. doi: 10.1016/j.bpg.2013.03.005.
    • (2013) Best Pract Res Clin Gastroenterol , vol.27 , pp. 47-58
    • Berry, D.1    Reinisch, W.2
  • 80
    • 69949120571 scopus 로고    scopus 로고
    • A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
    • Wu S, Rhee KJ, Albesiano E etal. A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses. Nat Med 2009; 15:1016-1022. doi: 10.1038/nm.2015.
    • (2009) Nat Med , vol.15 , pp. 1016-1022
    • Wu, S.1    Rhee, K.J.2    Albesiano, E.3
  • 81
    • 0037309735 scopus 로고    scopus 로고
    • Bacteroides fragilis enterotoxin induces c-Myc expression and cellular proliferation
    • Wu S, Morin PJ, Maouyo D, Sears CL. Bacteroides fragilis enterotoxin induces c-Myc expression and cellular proliferation. Gastroenterology 2003; 124:392-400. doi: 10.1053/gast.2003.50047.
    • (2003) Gastroenterology , vol.124 , pp. 392-400
    • Wu, S.1    Morin, P.J.2    Maouyo, D.3    Sears, C.L.4
  • 82
    • 0036209728 scopus 로고    scopus 로고
    • Enterococcus faecalis produces extracellular superoxide and hydrogen peroxide that damages colonic epithelial cell DNA
    • Huycke MM, Abrams V, Moore DR. Enterococcus faecalis produces extracellular superoxide and hydrogen peroxide that damages colonic epithelial cell DNA. Carcinogenesis 2002; 23:529-536.
    • (2002) Carcinogenesis , vol.23 , pp. 529-536
    • Huycke, M.M.1    Abrams, V.2    Moore, D.R.3
  • 83
    • 33747137269 scopus 로고    scopus 로고
    • Escherichia coli induces DNA double-strand breaks in eukaryotic cells
    • Nougayrede JP, Homburg S, Taieb F etal. Escherichia coli induces DNA double-strand breaks in eukaryotic cells. Science 2006; 313:848-851. doi: 10.1126/science.1127059.
    • (2006) Science , vol.313 , pp. 848-851
    • Nougayrede, J.P.1    Homburg, S.2    Taieb, F.3
  • 84
    • 77954730486 scopus 로고    scopus 로고
    • Escherichia coli induces DNA damage in vivo and triggers genomic instability in mammalian cells
    • Cuevas-Ramos G, Petit CR, Marcq I, Boury M, Oswald E, Nougayrede JP. Escherichia coli induces DNA damage in vivo and triggers genomic instability in mammalian cells. Proc Natl Acad Sci USA 2010; 107:11537-11542. doi: 10.1073/pnas.1001261107.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 11537-11542
    • Cuevas-Ramos, G.1    Petit, C.R.2    Marcq, I.3    Boury, M.4    Oswald, E.5    Nougayrede, J.P.6
  • 85
    • 84867218246 scopus 로고    scopus 로고
    • Cancer. Bacteria deliver a genotoxic hit
    • Schwabe RF, Wang TC. Cancer. Bacteria deliver a genotoxic hit. Science 2012; 338:52-53. doi: 10.1126/science.1229905.
    • (2012) Science , vol.338 , pp. 52-53
    • Schwabe, R.F.1    Wang, T.C.2
  • 86
    • 79953304882 scopus 로고    scopus 로고
    • Novel clues on the specific association of Streptococcus gallolyticus subsp. gallolyticus with colorectal cancer
    • Boleij A, Muytjens CM, Bukhari SI etal. Novel clues on the specific association of Streptococcus gallolyticus subsp. gallolyticus with colorectal cancer. J Infect Dis 2011; 203:1101-1109. doi: 10.1093/infdis/jiq169.
    • (2011) J Infect Dis , vol.203 , pp. 1101-1109
    • Boleij, A.1    Muytjens, C.M.2    Bukhari, S.I.3
  • 87
    • 60849136920 scopus 로고    scopus 로고
    • Association between Streptococcus bovis and colon cancer
    • Boleij A, Schaeps RM, Tjalsma H. Association between Streptococcus bovis and colon cancer. J Clin Microbiol 2009; 47:516. doi: 10.1128/JCM.01755-08.
    • (2009) J Clin Microbiol , vol.47 , pp. 516
    • Boleij, A.1    Schaeps, R.M.2    Tjalsma, H.3
  • 88
    • 84863022950 scopus 로고    scopus 로고
    • Genomic analysis identifies association of Fusobacterium with colorectal carcinoma
    • Kostic AD, Gevers D, Pedamallu CS etal. Genomic analysis identifies association of Fusobacterium with colorectal carcinoma. Genome Res 2012; 22:292-298. doi: 10.1101/gr.126573.111.
    • (2012) Genome Res , vol.22 , pp. 292-298
    • Kostic, A.D.1    Gevers, D.2    Pedamallu, C.S.3
  • 90
    • 84902300116 scopus 로고    scopus 로고
    • Gastrointestinal variant of Lemierre syndrome: Fusobacterium nucleatum bacteremia-associated hepatic vein thrombosis: a case report and literature review
    • Zheng L, Giri B. Gastrointestinal variant of Lemierre syndrome: Fusobacterium nucleatum bacteremia-associated hepatic vein thrombosis: a case report and literature review. Am J Ther 2014; doi: 10.1097/MJT.0000000000000084.
    • (2014) Am J Ther
    • Zheng, L.1    Giri, B.2
  • 91
    • 33845901507 scopus 로고    scopus 로고
    • Microbial ecology: human gut microbes associated with obesity
    • Ley RE, Turnbaugh PJ, Klein S, Gordon JI. Microbial ecology: human gut microbes associated with obesity. Nature 2006; 444:1022-1023. doi: 10.1038/4441022a.
    • (2006) Nature , vol.444 , pp. 1022-1023
    • Ley, R.E.1    Turnbaugh, P.J.2    Klein, S.3    Gordon, J.I.4
  • 92
    • 84907528345 scopus 로고    scopus 로고
    • Effects of antibiotics on human microbiota and subsequent disease
    • Keeney KM, Yurist-Doutsch S, Arrieta MC, Finlay BB. Effects of antibiotics on human microbiota and subsequent disease. Annu Rev Microbiol 2014; 68:217-235. doi: 10.1146/annurev-micro-091313-103456.
    • (2014) Annu Rev Microbiol , vol.68 , pp. 217-235
    • Keeney, K.M.1    Yurist-Doutsch, S.2    Arrieta, M.C.3    Finlay, B.B.4
  • 93
    • 41849127118 scopus 로고    scopus 로고
    • Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome
    • Turnbaugh PJ, Backhed F, Fulton L, Gordon JI. Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome. Cell Host Microbe 2008; 3:213-223. doi: 10.1016/j.chom.2008.02.015.
    • (2008) Cell Host Microbe , vol.3 , pp. 213-223
    • Turnbaugh, P.J.1    Backhed, F.2    Fulton, L.3    Gordon, J.I.4
  • 94
    • 78650616947 scopus 로고    scopus 로고
    • Toward defining the autoimmune microbiome for type 1 diabetes
    • Giongo A, Gano KA, Crabb DB etal. Toward defining the autoimmune microbiome for type 1 diabetes. ISME J 2011; 5:82-91. doi: 10.1038/ismej.2010.92.
    • (2011) ISME J , vol.5 , pp. 82-91
    • Giongo, A.1    Gano, K.A.2    Crabb, D.B.3
  • 95
    • 33746750046 scopus 로고    scopus 로고
    • Antibiotic treatment partially protects against type 1 diabetes in the Bio-Breeding diabetes-prone rat. Is the gut flora involved in the development of type 1 diabetes?
    • Brugman S, Klatter FA, Visser JT etal. Antibiotic treatment partially protects against type 1 diabetes in the Bio-Breeding diabetes-prone rat. Is the gut flora involved in the development of type 1 diabetes? Diabetologia 2006; 49:2105-2108. doi: 10.1007/s00125-006-0334-0.
    • (2006) Diabetologia , vol.49 , pp. 2105-2108
    • Brugman, S.1    Klatter, F.A.2    Visser, J.T.3
  • 96
    • 0033975581 scopus 로고    scopus 로고
    • Human immunosenescence: the prevailing of innate immunity, the failing of clonotypic immunity, and the filling of immunological space
    • Franceschi C, Bonafe M, Valensin S. Human immunosenescence: the prevailing of innate immunity, the failing of clonotypic immunity, and the filling of immunological space. Vaccine 2000; 18:1717-1720.
    • (2000) Vaccine , vol.18 , pp. 1717-1720
    • Franceschi, C.1    Bonafe, M.2    Valensin, S.3
  • 97
    • 0027381336 scopus 로고
    • Lymphocyte subsets and natural killer cell activity in healthy old people and centenarians
    • Sansoni P, Cossarizza A, Brianti V etal. Lymphocyte subsets and natural killer cell activity in healthy old people and centenarians. Blood 1993; 82:2767-2773.
    • (1993) Blood , vol.82 , pp. 2767-2773
    • Sansoni, P.1    Cossarizza, A.2    Brianti, V.3
  • 98
    • 10744223612 scopus 로고    scopus 로고
    • Marked increase with age of type 1 cytokines within memory and effector/cytotoxic CD8+ T cells in humans: a contribution to understand the relationship between inflammation and immunosenescence
    • Zanni F, Vescovini R, Biasini C etal. Marked increase with age of type 1 cytokines within memory and effector/cytotoxic CD8+ T cells in humans: a contribution to understand the relationship between inflammation and immunosenescence. Exp Gerontol 2003; 38:981-987.
    • (2003) Exp Gerontol , vol.38 , pp. 981-987
    • Zanni, F.1    Vescovini, R.2    Biasini, C.3
  • 99
    • 0033911488 scopus 로고    scopus 로고
    • Inflamm-aging. An evolutionary perspective on immunosenescence
    • Franceschi C, Bonafe M, Valensin S etal. Inflamm-aging. An evolutionary perspective on immunosenescence. Ann NY Acad Sci 2000; 908:244-254.
    • (2000) Ann NY Acad Sci , vol.908 , pp. 244-254
    • Franceschi, C.1    Bonafe, M.2    Valensin, S.3
  • 100
    • 0034809035 scopus 로고    scopus 로고
    • Inflammatory bowel disease is associated with changes of enterocytic junctions
    • Gassler N, Rohr C, Schneider A etal. Inflammatory bowel disease is associated with changes of enterocytic junctions. Am J Physiol Gastrointest Liver Physiol 2001; 281:G216-228.
    • (2001) Am J Physiol Gastrointest Liver Physiol , vol.281 , pp. G216-G228
    • Gassler, N.1    Rohr, C.2    Schneider, A.3
  • 101
    • 33845995125 scopus 로고    scopus 로고
    • Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease
    • Zeissig S, Burgel N, Gunzel D etal. Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease. Gut 2007; 56:61-72. doi: 10.1136/gut.2006.094375.
    • (2007) Gut , vol.56 , pp. 61-72
    • Zeissig, S.1    Burgel, N.2    Gunzel, D.3
  • 102
    • 50249086073 scopus 로고    scopus 로고
    • XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease
    • Kaser A, Lee AH, Franke A etal. XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease. Cell 2008; 134:743-756. doi: 10.1016/j.cell.2008.07.021.
    • (2008) Cell , vol.134 , pp. 743-756
    • Kaser, A.1    Lee, A.H.2    Franke, A.3
  • 103
    • 41549092745 scopus 로고    scopus 로고
    • Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis
    • Heazlewood CK, Cook MC, Eri R etal. Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis. PLOS Med 2008; 5:e54. doi: 10.1371/journal.pmed.0050054.
    • (2008) PLOS Med , vol.5 , pp. e54
    • Heazlewood, C.K.1    Cook, M.C.2    Eri, R.3
  • 104
    • 74049122536 scopus 로고    scopus 로고
    • Enteric defensins are essential regulators of intestinal microbial ecology
    • Salzman NH, Hung K, Haribhai D etal. Enteric defensins are essential regulators of intestinal microbial ecology. Nat Immunol 2010; 11:76-83. doi: 10.1038/ni.1825.
    • (2010) Nat Immunol , vol.11 , pp. 76-83
    • Salzman, N.H.1    Hung, K.2    Haribhai, D.3
  • 105
    • 34848889673 scopus 로고    scopus 로고
    • Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system
    • Garrett WS, Lord GM, Punit S etal. Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system. Cell 2007; 131:33-45. doi: 10.1016/j.cell.2007.08.017.
    • (2007) Cell , vol.131 , pp. 33-45
    • Garrett, W.S.1    Lord, G.M.2    Punit, S.3
  • 106
    • 35348857386 scopus 로고    scopus 로고
    • Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
    • Frank DN, St Amand AL, Feldman RA, Boedeker EC, Harpaz N, Pace NR. Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc Natl Acad Sci USA 2007; 104:13780-13785. doi: 10.1073/pnas.0706625104.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 13780-13785
    • Frank, D.N.1    St Amand, A.L.2    Feldman, R.A.3    Boedeker, E.C.4    Harpaz, N.5    Pace, N.R.6
  • 107
    • 78650155416 scopus 로고    scopus 로고
    • Highlighting new phylogenetic specificities of Crohn's disease microbiota
    • Mondot S, Kang S, Furet JP etal. Highlighting new phylogenetic specificities of Crohn's disease microbiota. Inflamm Bowel Dis 2011; 17:185-192. doi: 10.1002/ibd.21436.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 185-192
    • Mondot, S.1    Kang, S.2    Furet, J.P.3
  • 108
    • 33751556362 scopus 로고    scopus 로고
    • Abnormal microbiota composition in the ileocolonic mucosa of Crohn's disease patients as revealed by polymerase chain reaction-denaturing gradient gel electrophoresis
    • Martinez-Medina M, Aldeguer X, Gonzalez-Huix F, Acero D, Garcia-Gil LJ. Abnormal microbiota composition in the ileocolonic mucosa of Crohn's disease patients as revealed by polymerase chain reaction-denaturing gradient gel electrophoresis. Inflamm Bowel Dis 2006; 12:1136-1145. doi: 10.1097/01.mib.0000235828.09305.0c.
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 1136-1145
    • Martinez-Medina, M.1    Aldeguer, X.2    Gonzalez-Huix, F.3    Acero, D.4    Garcia-Gil, L.J.5
  • 109
    • 78149283854 scopus 로고    scopus 로고
    • Mucolytic bacteria with increased prevalence in IBD mucosa augment in vitro utilization of mucin by other bacteria
    • Png CW, Linden SK, Gilshenan KS etal. Mucolytic bacteria with increased prevalence in IBD mucosa augment in vitro utilization of mucin by other bacteria. Am J Gastroenterol 2010; 105:2420-2428. doi: 10.1038/ajg.2010.281.
    • (2010) Am J Gastroenterol , vol.105 , pp. 2420-2428
    • Png, C.W.1    Linden, S.K.2    Gilshenan, K.S.3
  • 110
    • 34547714253 scopus 로고    scopus 로고
    • Terminal restriction fragment length polymorphism analysis of the diversity of fecal microbiota in patients with ulcerative colitis
    • Andoh A, Sakata S, Koizumi Y, Mitsuyama K, Fujiyama Y, Benno Y. Terminal restriction fragment length polymorphism analysis of the diversity of fecal microbiota in patients with ulcerative colitis. Inflamm Bowel Dis 2007; 13:955-962. doi: 10.1002/ibd.20151.
    • (2007) Inflamm Bowel Dis , vol.13 , pp. 955-962
    • Andoh, A.1    Sakata, S.2    Koizumi, Y.3    Mitsuyama, K.4    Fujiyama, Y.5    Benno, Y.6
  • 111
    • 34047167850 scopus 로고    scopus 로고
    • Comparative study of the intestinal mucus barrier in normal and inflamed colon
    • Swidsinski A, Loening-Baucke V, Theissig F etal. Comparative study of the intestinal mucus barrier in normal and inflamed colon. Gut 2007; 56:343-350. doi: 10.1136/gut.2006.098160.
    • (2007) Gut , vol.56 , pp. 343-350
    • Swidsinski, A.1    Loening-Baucke, V.2    Theissig, F.3
  • 112
    • 0031758230 scopus 로고    scopus 로고
    • Presence of adherent Escherichia coli strains in ileal mucosa of patients with Crohn's disease
    • Darfeuille-Michaud A, Neut C, Barnich N etal. Presence of adherent Escherichia coli strains in ileal mucosa of patients with Crohn's disease. Gastroenterology 1998; 115:1405-1413.
    • (1998) Gastroenterology , vol.115 , pp. 1405-1413
    • Darfeuille-Michaud, A.1    Neut, C.2    Barnich, N.3
  • 113
    • 0032768352 scopus 로고    scopus 로고
    • Invasive ability of an Escherichia coli strain isolated from the ileal mucosa of a patient with Crohn's disease
    • Boudeau J, Glasser AL, Masseret E, Joly B, Darfeuille-Michaud A. Invasive ability of an Escherichia coli strain isolated from the ileal mucosa of a patient with Crohn's disease. Infect Immun 1999; 67:4499-4509.
    • (1999) Infect Immun , vol.67 , pp. 4499-4509
    • Boudeau, J.1    Glasser, A.L.2    Masseret, E.3    Joly, B.4    Darfeuille-Michaud, A.5
  • 114
    • 77649194674 scopus 로고    scopus 로고
    • Crohn's disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly
    • Lapaquette P, Glasser AL, Huett A, Xavier RJ, Darfeuille-Michaud A. Crohn's disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly. Cell Microbiol 2010; 12:99-113. doi: 10.1111/j.1462-5822.2009.01381.x.
    • (2010) Cell Microbiol , vol.12 , pp. 99-113
    • Lapaquette, P.1    Glasser, A.L.2    Huett, A.3    Xavier, R.J.4    Darfeuille-Michaud, A.5
  • 115
    • 79952134938 scopus 로고    scopus 로고
    • A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease
    • Brest P, Lapaquette P, Souidi M etal. A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease. Nat Genet 2011; 43:242-245. doi: 10.1038/ng.762.
    • (2011) Nat Genet , vol.43 , pp. 242-245
    • Brest, P.1    Lapaquette, P.2    Souidi, M.3
  • 116
    • 34249886868 scopus 로고    scopus 로고
    • CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease
    • Barnich N, Carvalho FA, Glasser AL etal. CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease. J Clin Invest 2007; 117:1566-1574. doi: 10.1172/JCI30504.
    • (2007) J Clin Invest , vol.117 , pp. 1566-1574
    • Barnich, N.1    Carvalho, F.A.2    Glasser, A.L.3
  • 117
    • 84867192879 scopus 로고    scopus 로고
    • Intestinal inflammation targets cancer-inducing activity of the microbiota
    • Arthur JC, Perez-Chanona E, Muhlbauer M etal. Intestinal inflammation targets cancer-inducing activity of the microbiota. Science 2012; 338:120-123. doi: 10.1126/science.1224820.
    • (2012) Science , vol.338 , pp. 120-123
    • Arthur, J.C.1    Perez-Chanona, E.2    Muhlbauer, M.3
  • 118
    • 84878971321 scopus 로고    scopus 로고
    • Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer
    • Hu B, Elinav E, Huber S etal. Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer. Proc Natl Acad Sci USA 2013; 110:9862-9867. doi: 10.1073/pnas.1307575110.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 9862-9867
    • Hu, B.1    Elinav, E.2    Huber, S.3
  • 119
    • 85027927719 scopus 로고    scopus 로고
    • Enterotypes of the human gut microbiome
    • Arumugam M, Raes J, Pelletier E etal. Enterotypes of the human gut microbiome. Nature 2011; 473:174-180. doi: 10.1038/nature09944.
    • (2011) Nature , vol.473 , pp. 174-180
    • Arumugam, M.1    Raes, J.2    Pelletier, E.3
  • 120
    • 80053618114 scopus 로고    scopus 로고
    • Linking long-term dietary patterns with gut microbial enterotypes
    • Wu GD, Chen J, Hoffmann C etal. Linking long-term dietary patterns with gut microbial enterotypes. Science 2011; 334:105-108. doi: 10.1126/science.1208344.
    • (2011) Science , vol.334 , pp. 105-108
    • Wu, G.D.1    Chen, J.2    Hoffmann, C.3
  • 121
    • 70350110294 scopus 로고    scopus 로고
    • High-fat diet determines the composition of the murine gut microbiome independently of obesity
    • 1716-24e1-2
    • Hildebrandt MA, Hoffmann C, Sherrill-Mix SA etal. High-fat diet determines the composition of the murine gut microbiome independently of obesity. Gastroenterology 2009; 137:1716-24.e1-2. doi: 10.1053/j.gastro.2009.08.042.
    • (2009) Gastroenterology , vol.137
    • Hildebrandt, M.A.1    Hoffmann, C.2    Sherrill-Mix, S.A.3
  • 122
    • 84855488068 scopus 로고    scopus 로고
    • A vegan or vegetarian diet substantially alters the human colonic faecal microbiota
    • Zimmer J, Lange B, Frick JS etal. A vegan or vegetarian diet substantially alters the human colonic faecal microbiota. Eur J Clin Nutr 2012; 66:53-60. doi: 10.1038/ejcn.2011.141.
    • (2012) Eur J Clin Nutr , vol.66 , pp. 53-60
    • Zimmer, J.1    Lange, B.2    Frick, J.S.3
  • 123
    • 84866124791 scopus 로고    scopus 로고
    • Faecal microbiota composition in vegetarians: comparison with omnivores in a cohort of young women in southern India
    • Kabeerdoss J, Devi RS, Mary RR, Ramakrishna BS. Faecal microbiota composition in vegetarians: comparison with omnivores in a cohort of young women in southern India. Br J Nutr 2012; 108:953-957. doi: 10.1017/S0007114511006362.
    • (2012) Br J Nutr , vol.108 , pp. 953-957
    • Kabeerdoss, J.1    Devi, R.S.2    Mary, R.R.3    Ramakrishna, B.S.4
  • 124
    • 84892828465 scopus 로고    scopus 로고
    • Diet rapidly and reproducibly alters the human gut microbiome
    • David LA, Maurice CF, Carmody RN etal. Diet rapidly and reproducibly alters the human gut microbiome. Nature 2014; 23:559-563. doi: 10.1038/nature12820.
    • (2014) Nature , vol.23 , pp. 559-563
    • David, L.A.1    Maurice, C.F.2    Carmody, R.N.3
  • 125
    • 14744287885 scopus 로고    scopus 로고
    • Polyphenols and prevention of cardiovascular diseases
    • Manach C, Mazur A, Scalbert A. Polyphenols and prevention of cardiovascular diseases. Curr Opin Lipidol 2005; 16:77-84.
    • (2005) Curr Opin Lipidol , vol.16 , pp. 77-84
    • Manach, C.1    Mazur, A.2    Scalbert, A.3
  • 126
    • 12844272321 scopus 로고    scopus 로고
    • Polyphenols and disease risk in epidemiologic studies
    • Arts IC, Hollman PC. Polyphenols and disease risk in epidemiologic studies. Am J Clin Nutr 2005; 81 (1 Suppl.):317S-325.
    • (2005) Am J Clin Nutr , vol.81 , Issue.1 , pp. 317S-3325
    • Arts, I.C.1    Hollman, P.C.2
  • 128
    • 0016571597 scopus 로고
    • Cancer epidemiology in populations of the United States - with emphasis on Hawaii and California - and Japan
    • Dunn JE. Cancer epidemiology in populations of the United States - with emphasis on Hawaii and California - and Japan. Cancer Res 1975; 35:3240-3245.
    • (1975) Cancer Res , vol.35 , pp. 3240-3245
    • Dunn, J.E.1
  • 129
    • 0018387466 scopus 로고
    • Breast-cancer incidence and mortality rates in different countries in relation to known risk factors and dietary practices
    • Gray GE, Pike MC, Henderson BE. Breast-cancer incidence and mortality rates in different countries in relation to known risk factors and dietary practices. Br J Cancer 1979; 39:1-7.
    • (1979) Br J Cancer , vol.39 , pp. 1-7
    • Gray, G.E.1    Pike, M.C.2    Henderson, B.E.3
  • 130
    • 0028216956 scopus 로고
    • Soy intake and cancer risk: a review of the in vitro and in vivo data
    • Messina MJ, Persky V, Setchell KD, Barnes S. Soy intake and cancer risk: a review of the in vitro and in vivo data. Nutr Cancer 1994; 21:113-131. doi: 10.1080/01635589409514310.
    • (1994) Nutr Cancer , vol.21 , pp. 113-131
    • Messina, M.J.1    Persky, V.2    Setchell, K.D.3    Barnes, S.4
  • 131
    • 0021908716 scopus 로고
    • Naturally occurring oestrogens in foods - a review
    • Price KR, Fenwick GR. Naturally occurring oestrogens in foods - a review. Food Addit Contam 1985; 2:73-106. doi: 10.1080/02652038509373531.
    • (1985) Food Addit Contam , vol.2 , pp. 73-106
    • Price, K.R.1    Fenwick, G.R.2
  • 132
    • 34948823424 scopus 로고    scopus 로고
    • Microbial and dietary factors are associated with the equol producer phenotype in healthy postmenopausal women
    • Bolca S, Possemiers S, Herregat A etal. Microbial and dietary factors are associated with the equol producer phenotype in healthy postmenopausal women. J Nutr 2007; 137:2242-2246.
    • (2007) J Nutr , vol.137 , pp. 2242-2246
    • Bolca, S.1    Possemiers, S.2    Herregat, A.3
  • 134
    • 1542319924 scopus 로고    scopus 로고
    • Equol, a natural estrogenic metabolite from soy isoflavones: convenient preparation and resolution of R- and S-equols and their differing binding and biological activity through estrogen receptors alpha and beta
    • Muthyala RS, Ju YH, Sheng S etal. Equol, a natural estrogenic metabolite from soy isoflavones: convenient preparation and resolution of R- and S-equols and their differing binding and biological activity through estrogen receptors alpha and beta. Bioorg Med Chem 2004; 12:1559-1567. doi: 10.1016/j.bmc.2003.11.035.
    • (2004) Bioorg Med Chem , vol.12 , pp. 1559-1567
    • Muthyala, R.S.1    Ju, Y.H.2    Sheng, S.3
  • 135
    • 0028126083 scopus 로고
    • Effects of infant nutrition on cholesterol synthesis rates
    • Cruz ML, Wong WW, Mimouni F etal. Effects of infant nutrition on cholesterol synthesis rates. Pediatr Res 1994; 35:135-140. doi: 10.1203/00006450-199402000-00001.
    • (1994) Pediatr Res , vol.35 , pp. 135-140
    • Cruz, M.L.1    Wong, W.W.2    Mimouni, F.3
  • 137
    • 1542376914 scopus 로고    scopus 로고
    • In vitro incubation of human feces with daidzein and antibiotics suggests interindividual differences in the bacteria responsible for equol production
    • Atkinson C, Berman S, Humbert O, Lampe JW. In vitro incubation of human feces with daidzein and antibiotics suggests interindividual differences in the bacteria responsible for equol production. J Nutr 2004; 134:596-599.
    • (2004) J Nutr , vol.134 , pp. 596-599
    • Atkinson, C.1    Berman, S.2    Humbert, O.3    Lampe, J.W.4
  • 138
    • 2442502878 scopus 로고    scopus 로고
    • Serum steroid hormones, sex hormone-binding globulin concentrations, and urinary hydroxylated estrogen metabolites in post- menopausal women in relation to daidzein-metabolizing phenotypes
    • Frankenfeld CL, McTiernan A, Tworoger SS etal. Serum steroid hormones, sex hormone-binding globulin concentrations, and urinary hydroxylated estrogen metabolites in post- menopausal women in relation to daidzein-metabolizing phenotypes. J Steroid Biochem Mol Biol 2004; 88:399-408. doi: 10.1016/j.jsbmb.2004.01.006.
    • (2004) J Steroid Biochem Mol Biol , vol.88 , pp. 399-408
    • Frankenfeld, C.L.1    McTiernan, A.2    Tworoger, S.S.3
  • 139
    • 0034114568 scopus 로고    scopus 로고
    • Interindividual variation in metabolism of soy isoflavones and lignans: influence of habitual diet on equol production by the gut microflora
    • Rowland IR, Wiseman H, Sanders TA, Adlercreutz H, Bowey EA. Interindividual variation in metabolism of soy isoflavones and lignans: influence of habitual diet on equol production by the gut microflora. Nutr Cancer 2000; 36:27-32. doi: 10.1207/S15327914NC3601_5.
    • (2000) Nutr Cancer , vol.36 , pp. 27-32
    • Rowland, I.R.1    Wiseman, H.2    Sanders, T.A.3    Adlercreutz, H.4    Bowey, E.A.5
  • 140
    • 7944228805 scopus 로고    scopus 로고
    • Familial correlations, segregation analysis, and nongenetic correlates of soy isoflavone-metabolizing phenotypes
    • Frankenfeld CL, Atkinson C, Thomas WK etal. Familial correlations, segregation analysis, and nongenetic correlates of soy isoflavone-metabolizing phenotypes. Exp Biol Med 2004; 229:902-913.
    • (2004) Exp Biol Med , vol.229 , pp. 902-913
    • Frankenfeld, C.L.1    Atkinson, C.2    Thomas, W.K.3
  • 141
    • 70450247135 scopus 로고    scopus 로고
    • Fecal bacteriotherapy for recurrent Clostridium difficile infection
    • Bakken JS. Fecal bacteriotherapy for recurrent Clostridium difficile infection. Anaerobe 2009; 15:285-289. doi: 10.1016/j.anaerobe.2009.09.007.
    • (2009) Anaerobe , vol.15 , pp. 285-289
    • Bakken, J.S.1
  • 142
    • 84868361276 scopus 로고    scopus 로고
    • Toward an understanding of changes in diversity associated with fecal microbiome transplantation based on 16S rRNA gene deep sequencing
    • e00338-e00312
    • Shahinas D, Silverman M, Sittler T etal. Toward an understanding of changes in diversity associated with fecal microbiome transplantation based on 16S rRNA gene deep sequencing. MBio 2012; 23: pii: e00338-12. doi: 10.1128/mBio.00338-12.
    • (2012) MBio , vol.23
    • Shahinas, D.1    Silverman, M.2    Sittler, T.3
  • 143
    • 33750943795 scopus 로고    scopus 로고
    • Bifidobacterium infantis strains with and without a combination of oligofructose and inulin (OFI) attenuate inflammation in DSS-induced colitis in rats
    • Osman N, Adawi D, Molin G, Ahrne S, Berggren A, Jeppsson B. Bifidobacterium infantis strains with and without a combination of oligofructose and inulin (OFI) attenuate inflammation in DSS-induced colitis in rats. BMC Gastroenterol 2006; 6:31. doi: 10.1186/1471-230X-6-31.
    • (2006) BMC Gastroenterol , vol.6 , pp. 31
    • Osman, N.1    Adawi, D.2    Molin, G.3    Ahrne, S.4    Berggren, A.5    Jeppsson, B.6
  • 144
    • 0036197778 scopus 로고    scopus 로고
    • Dietary oligofructose and inulin protect mice from enteric and systemic pathogens and tumor inducers
    • Buddington KK, Donahoo JB, Buddington RK. Dietary oligofructose and inulin protect mice from enteric and systemic pathogens and tumor inducers. J Nutr 2002; 132:472-477.
    • (2002) J Nutr , vol.132 , pp. 472-477
    • Buddington, K.K.1    Donahoo, J.B.2    Buddington, R.K.3
  • 145
    • 84880417771 scopus 로고    scopus 로고
    • Probiotic bacteria reduce Salmonella typhimurium intestinal colonization by competing for iron
    • Deriu E, Liu JZ, Pezeshki M etal. Probiotic bacteria reduce Salmonella typhimurium intestinal colonization by competing for iron. Cell Host Microbe 2013; 14:26-37. doi: 10.1016/j.chom.2013.06.007.
    • (2013) Cell Host Microbe , vol.14 , pp. 26-37
    • Deriu, E.1    Liu, J.Z.2    Pezeshki, M.3
  • 146
    • 80054960299 scopus 로고    scopus 로고
    • The impact of a consortium of fermented milk strains on the gut microbiome of gnotobiotic mice and monozygotic twins
    • McNulty NP, Yatsunenko T, Hsiao A etal. The impact of a consortium of fermented milk strains on the gut microbiome of gnotobiotic mice and monozygotic twins. Sci Transl Med 2011; 3:106ra. doi: 10.1126/scitranslmed.3002701.
    • (2011) Sci Transl Med , vol.3 , pp. 106ra
    • McNulty, N.P.1    Yatsunenko, T.2    Hsiao, A.3


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