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Volumn 12, Issue 12, 2006, Pages 1136-1145

Abnormal microbiota composition in the ileocolonic mucosa of Crohn's disease patients as revealed by polymerase chain reaction-denaturing gradient gel electrophoresis

Author keywords

Crohn's disease; Inflammatory bowel disease; Molecular microbiology; Mucosa; PCR DGGE

Indexed keywords

CORTICOSTEROID; IMMUNOSUPPRESSIVE AGENT; MESALAZINE; RNA 16S; TUMOR NECROSIS FACTOR ANTIBODY;

EID: 33751556362     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1097/01.mib.0000235828.09305.0c     Document Type: Article
Times cited : (210)

References (51)
  • 1
    • 22744455129 scopus 로고    scopus 로고
    • The mycobacteria story in Crohn's disease
    • Shanahan F, O'Mahony J. The mycobacteria story in Crohn's disease. Am J Gastroenterol. 2005;100:1537-1538.
    • (2005) Am J Gastroenterol , vol.100 , pp. 1537-1538
    • Shanahan, F.1    O'Mahony, J.2
  • 2
    • 0035978651 scopus 로고    scopus 로고
    • Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
    • Hugot JP, Chamaillard M, Zouali H, et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature. 2001;411:599-603.
    • (2001) Nature , vol.411 , pp. 599-603
    • Hugot, J.P.1    Chamaillard, M.2    Zouali, H.3
  • 3
    • 13144261748 scopus 로고    scopus 로고
    • Identification of novel susceptibility loci for inflammatory bowel disease on chromosomes 1p, 3q, and 4q: Evidence for epistasis between 1p and IBD1
    • Cho JH, Nicolae DL, Gold LH, et al. Identification of novel susceptibility loci for inflammatory bowel disease on chromosomes 1p, 3q, and 4q: evidence for epistasis between 1p and IBD1. Proc Natl Acad Sci U S A. 1998;95:7502-7507.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 7502-7507
    • Cho, J.H.1    Nicolae, D.L.2    Gold, L.H.3
  • 4
    • 0346734343 scopus 로고    scopus 로고
    • Crohn's disease: The cold chain hypothesis
    • Hugot JP, Alberti C, Berrebi D, et al. Crohn's disease: the cold chain hypothesis. Lancet. 2003;362:2012-2015.
    • (2003) Lancet , vol.362 , pp. 2012-2015
    • Hugot, J.P.1    Alberti, C.2    Berrebi, D.3
  • 5
    • 0037148940 scopus 로고    scopus 로고
    • Genes, microbes, and T cells: New therapeutic targets in Crohn's disease
    • Elson CO. Genes, microbes, and T cells: new therapeutic targets in Crohn's disease. N Engl J Med. 2002;346:614-616.
    • (2002) N Engl J Med , vol.346 , pp. 614-616
    • Elson, C.O.1
  • 6
    • 0037302961 scopus 로고    scopus 로고
    • Alterations of the dominant faecal bacterial groups in patients with Crohn's disease of the colon
    • Seksik P, Rigottier-Gois L, Gramet G, et al. Alterations of the dominant faecal bacterial groups in patients with Crohn's disease of the colon. Gut. 2003;52:237-242.
    • (2003) Gut , vol.52 , pp. 237-242
    • Seksik, P.1    Rigottier-Gois, L.2    Gramet, G.3
  • 7
    • 4644231021 scopus 로고    scopus 로고
    • Molecular inventory of faecal microflora in patients with Crohn's disease
    • Mangin I, Bonnet R, Seksik P, et al. Molecular inventory of faecal microflora in patients with Crohn's disease. FEMS Microbiol Ecol. 2004;50:25-36.
    • (2004) FEMS Microbiol Ecol , vol.50 , pp. 25-36
    • Mangin, I.1    Bonnet, R.2    Seksik, P.3
  • 8
    • 30944466824 scopus 로고    scopus 로고
    • Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach
    • Manichanh C, Rigottier-Gois L, Bonnaud E, et al. Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach. Gut. 2006;55:205-211.
    • (2006) Gut , vol.55 , pp. 205-211
    • Manichanh, C.1    Rigottier-Gois, L.2    Bonnaud, E.3
  • 9
    • 9144260143 scopus 로고    scopus 로고
    • Ribosomal DNA sequence analysis of mucosa-associated bacteria in Crohn's disease
    • Prindiville T, Cantrell M, Wilson KH. Ribosomal DNA sequence analysis of mucosa-associated bacteria in Crohn's disease. Inflamm Bowel Dis. 2004;10:824-833.
    • (2004) Inflamm Bowel Dis , vol.10 , pp. 824-833
    • Prindiville, T.1    Cantrell, M.2    Wilson, K.H.3
  • 11
    • 0031939085 scopus 로고    scopus 로고
    • Postoperative recurrence of Crohn's disease: The enemy is within the fecal stream
    • Sartor RB. Postoperative recurrence of Crohn's disease: the enemy is within the fecal stream. Gastroenterology. 1998;114:398-400.
    • (1998) Gastroenterology , vol.114 , pp. 398-400
    • Sartor, R.B.1
  • 12
    • 0033948508 scopus 로고    scopus 로고
    • Lessons from genetically engineered animal models. XII. IL-10-deficient (IL-10(-/-)) mice and intestinal inflammation
    • Rennick DM, Fort MM. Lessons from genetically engineered animal models. XII. IL-10-deficient (IL-10(-/-)) mice and intestinal inflammation. Am J Physiol Gastrointest Liver Physiol. 2000;278:829-833.
    • (2000) Am J Physiol Gastrointest Liver Physiol , vol.278 , pp. 829-833
    • Rennick, D.M.1    Fort, M.M.2
  • 13
    • 0038507158 scopus 로고    scopus 로고
    • Detection and verification of Mycobacterium avium subsp. paratuberculosis in fresh ileocolonic mucosal biopsy specimens from individuals with and without Crohn's disease
    • Bull TJ, McMinn EJ, Sidi-Boumedine K, et al. Detection and verification of Mycobacterium avium subsp. paratuberculosis in fresh ileocolonic mucosal biopsy specimens from individuals with and without Crohn's disease. J Clin Microbiol. 2003;41:2915-2923.
    • (2003) J Clin Microbiol , vol.41 , pp. 2915-2923
    • Bull, T.J.1    McMinn, E.J.2    Sidi-Boumedine, K.3
  • 14
    • 0036701673 scopus 로고    scopus 로고
    • Positive IS900 in situ hybridization signals as evidence for role of Mycobacterium avium subsp. paratuberculosis in etiology of Crohn's disease
    • Roholl PJ, Herrewegh A, van Soolingen D. Positive IS900 in situ hybridization signals as evidence for role of Mycobacterium avium subsp. paratuberculosis in etiology of Crohn's disease. J Clin Microbiol. 2002;40:3112.
    • (2002) J Clin Microbiol , vol.40 , pp. 3112
    • Roholl, P.J.1    Herrewegh, A.2    Van Soolingen, D.3
  • 15
    • 0042708022 scopus 로고    scopus 로고
    • Is Crohn's disease caused by a mycobacterium? Comparisons with leprosy, tuberculosis, and Johne's disease
    • Greenstein RJ. Is Crohn's disease caused by a mycobacterium? Comparisons with leprosy, tuberculosis, and Johne's disease. Lancet Infect Dis. 2003;3:507-514.
    • (2003) Lancet Infect Dis , vol.3 , pp. 507-514
    • Greenstein, R.J.1
  • 16
    • 0036838589 scopus 로고    scopus 로고
    • PCR detection of Mycobacterium paratuberculosis in Crohn's disease granulomas isolated by laser capture microdissection
    • Ryan P, Bennett MW, Aarons S, et al. PCR detection of Mycobacterium paratuberculosis in Crohn's disease granulomas isolated by laser capture microdissection. Gut. 2002;51:665-670.
    • (2002) Gut , vol.51 , pp. 665-670
    • Ryan, P.1    Bennett, M.W.2    Aarons, S.3
  • 17
    • 4444306100 scopus 로고    scopus 로고
    • Bacterial DNA within granulomas of patients with Crohn's disease: Detection by laser capture microdissection and PCR
    • Ryan P, Kelly RG, Lee G, et al. Bacterial DNA within granulomas of patients with Crohn's disease: detection by laser capture microdissection and PCR. Am J Gastroenterol. 2004;99:1539-1543.
    • (2004) Am J Gastroenterol , vol.99 , pp. 1539-1543
    • Ryan, P.1    Kelly, R.G.2    Lee, G.3
  • 18
    • 0029040860 scopus 로고
    • On the use of antibiotics in Crohn's disease
    • Van Kruiningen HJ. On the use of antibiotics in Crohn's disease. J Clin Gastroenterol. 1995;20:310-316.
    • (1995) J Clin Gastroenterol , vol.20 , pp. 310-316
    • Van Kruiningen, H.J.1
  • 21
    • 0027460328 scopus 로고
    • Profiling of complex microbial populations by denaturing gradient gel electrophoresis analysis of polymerase chain reaction-amplified genes coding for 16S rRNA
    • Muyzer G, de Waal EC, Uitterlinden AG. Profiling of complex microbial populations by denaturing gradient gel electrophoresis analysis of polymerase chain reaction-amplified genes coding for 16S rRNA. Appl Environ Microbiol. 1993;59:695-700.
    • (1993) Appl Environ Microbiol , vol.59 , pp. 695-700
    • Muyzer, G.1    De Waal, E.C.2    Uitterlinden, A.G.3
  • 22
    • 0029097821 scopus 로고
    • Phylogenetic relationships of Thiomicrospira species and their identification in deep-sea hydrothermal vent samples by denaturing gradient gel electrophoresis of 16S rDNA fragments
    • Muyzer G, Teske A, Wirsen CO, et al. Phylogenetic relationships of Thiomicrospira species and their identification in deep-sea hydrothermal vent samples by denaturing gradient gel electrophoresis of 16S rDNA fragments. Arch Microbiol. 1995;164:165-172.
    • (1995) Arch Microbiol , vol.164 , pp. 165-172
    • Muyzer, G.1    Teske, A.2    Wirsen, C.O.3
  • 23
    • 0002051540 scopus 로고    scopus 로고
    • BioEdit: A user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT
    • Hall T. BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT. Nucl Acids Symp Ser. 1999;41:95-98.
    • (1999) Nucl Acids Symp Ser , vol.41 , pp. 95-98
    • Hall, T.1
  • 24
    • 0031574072 scopus 로고    scopus 로고
    • The CLUSTAL_X windows interface: Flexible strategies for multiple sequence alignment aided by quality analysis tools
    • Thompson JD, Gibson TJ, Plewniak F, et al. The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res. 1997;25:4876-4882.
    • (1997) Nucleic Acids Res , vol.25 , pp. 4876-4882
    • Thompson, J.D.1    Gibson, T.J.2    Plewniak, F.3
  • 25
    • 0030801002 scopus 로고    scopus 로고
    • Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
    • Altschul SF, Madden TL, Schaffer AA, et al. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 1997;25:3389-3402.
    • (1997) Nucleic Acids Res , vol.25 , pp. 3389-3402
    • Altschul, S.F.1    Madden, T.L.2    Schaffer, A.A.3
  • 26
    • 15444362001 scopus 로고    scopus 로고
    • Introducing DOTUR, a computer program for defining operational taxonomic units and estimating species richness
    • Schloss PD, Handelsman J. Introducing DOTUR, a computer program for defining operational taxonomic units and estimating species richness. Appl Environ Microbiol. 2005;71:1501-1506.
    • (2005) Appl Environ Microbiol , vol.71 , pp. 1501-1506
    • Schloss, P.D.1    Handelsman, J.2
  • 27
    • 0003437299 scopus 로고
    • Seattle, Wash: Department of Genetics, University of Washington; Distributed by the author
    • Felsenstein J. PHYLIP (Phylogeny Inference Package), version 3.5c. Seattle, Wash: Department of Genetics, University of Washington; 1993. Distributed by the author.
    • (1993) PHYLIP (Phylogeny Inference Package), Version 3.5c
    • Felsenstein, J.1
  • 29
    • 0002912874 scopus 로고    scopus 로고
    • Application of denaturing gradient gel electrophoresis (DGGE) and temperature gradient gel electrophoresis (TGGE) for studying soil microbial communities
    • van Elsas JD, Wellington EMH, Trevors JT, eds. New York, NY: Marcel Dekker Inc
    • Heuer H, Smalla K. Application of denaturing gradient gel electrophoresis (DGGE) and temperature gradient gel electrophoresis (TGGE) for studying soil microbial communities. In: van Elsas JD, Wellington EMH, Trevors JT, eds. Modern Soil Microbiology. New York, NY: Marcel Dekker Inc; 1997:353-373.
    • (1997) Modern Soil Microbiology , pp. 353-373
    • Heuer, H.1    Smalla, K.2
  • 30
    • 0036185771 scopus 로고    scopus 로고
    • Assessment of microbial diversity in human colonic samples by 16S rDNA sequence analysis
    • Hold GL, Pryde SE, Russell VJ, et al. Assessment of microbial diversity in human colonic samples by 16S rDNA sequence analysis. FEMS Microbiol Ecol. 2002;39:33-39.
    • (2002) FEMS Microbiol Ecol , vol.39 , pp. 33-39
    • Hold, G.L.1    Pryde, S.E.2    Russell, V.J.3
  • 31
    • 0042882421 scopus 로고    scopus 로고
    • Molecular characterization of the microbial species that colonize human ileal and colonic mucosa by using 16S rDNA sequence analysis
    • Wang X, Heazlewood SP, Krause DO, et al. Molecular characterization of the microbial species that colonize human ileal and colonic mucosa by using 16S rDNA sequence analysis. J Appl Microbiol. 2003;95:508-520.
    • (2003) J Appl Microbiol , vol.95 , pp. 508-520
    • Wang, X.1    Heazlewood, S.P.2    Krause, D.O.3
  • 32
    • 20544444045 scopus 로고    scopus 로고
    • Diversity of the human intestinal microbial flora
    • Eckburg PB, Bik EM, Bernstein CN, et al. Diversity of the human intestinal microbial flora. Science. 2005;308:1635-1638.
    • (2005) Science , vol.308 , pp. 1635-1638
    • Eckburg, P.B.1    Bik, E.M.2    Bernstein, C.N.3
  • 33
    • 0036866628 scopus 로고    scopus 로고
    • Growth requirements and fermentation products of Fusobacterium prausnitzii, and a proposal to reclassify it as Faecalibacterium prausnitzii gen. nov., comb. nov.
    • Duncan SH, Hold GL, Harmsen HJM, et al. Growth requirements and fermentation products of Fusobacterium prausnitzii, and a proposal to reclassify it as Faecalibacterium prausnitzii gen. nov., comb. nov. Int J Syst Evol Microbiol. 2002;52:2141-2146.
    • (2002) Int J Syst Evol Microbiol , vol.52 , pp. 2141-2146
    • Duncan, S.H.1    Hold, G.L.2    Harmsen, H.J.M.3
  • 34
    • 0028126829 scopus 로고
    • The phylogeny of the genus Clostridium: Proposal of five new genera and eleven new species combinations
    • Collins MD, Lawson PA, Willems A, et al. The phylogeny of the genus Clostridium: proposal of five new genera and eleven new species combinations. Int J of Syst Bacteriol. 1994;44:812-826.
    • (1994) Int J of Syst Bacteriol , vol.44 , pp. 812-826
    • Collins, M.D.1    Lawson, P.A.2    Willems, A.3
  • 35
    • 21244481613 scopus 로고    scopus 로고
    • Clostridium clostridioforme: A mixture of three clinically important species
    • Finegold SM, Song Y, Liu C, et al. Clostridium clostridioforme: a mixture of three clinically important species. Eur J Clin Microbiol Infect Dis. 2005;24:319-324.
    • (2005) Eur J Clin Microbiol Infect Dis , vol.24 , pp. 319-324
    • Finegold, S.M.1    Song, Y.2    Liu, C.3
  • 36
    • 0035978533 scopus 로고    scopus 로고
    • A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
    • Ogura Y, Bonen DK, Inohara N, et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature. 2001;411:603-606.
    • (2001) Nature , vol.411 , pp. 603-606
    • Ogura, Y.1    Bonen, D.K.2    Inohara, N.3
  • 37
    • 22644441640 scopus 로고    scopus 로고
    • New IBD genes?
    • McGovern D, Ahmad T. New IBD genes? Gut. 2005;54:1060-1061.
    • (2005) Gut , vol.54 , pp. 1060-1061
    • McGovern, D.1    Ahmad, T.2
  • 38
    • 14644414161 scopus 로고    scopus 로고
    • Defence molecules in intestinal innate immunity against bacterial infections
    • Eckmann L. Defence molecules in intestinal innate immunity against bacterial infections. Curr Opin Gastroenterol. 2005;21:147-151.
    • (2005) Curr Opin Gastroenterol , vol.21 , pp. 147-151
    • Eckmann, L.1
  • 39
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol. 2004;4:499-511.
    • (2004) Nat Rev Immunol , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 40
    • 0036300743 scopus 로고    scopus 로고
    • Mucosa-associated bacteria in the human gastrointestinal tract are uniformly distributed along the colon and differ from the community recovered from feces
    • Zoetendal EG, von Wright A, Vilpponen-Salmela T, et al. Mucosa-associated bacteria in the human gastrointestinal tract are uniformly distributed along the colon and differ from the community recovered from feces. Appl Environ Microbiol. 2002;68:3401-3407.
    • (2002) Appl Environ Microbiol , vol.68 , pp. 3401-3407
    • Zoetendal, E.G.1    Von Wright, A.2    Vilpponen-Salmela, T.3
  • 41
    • 0037478707 scopus 로고    scopus 로고
    • Oligonucleotide probes that detect quantitatively significant groups of butyrate-producing bacteria in human feces
    • Hold GL, Schwiertz A, Aminov RI, et al. Oligonucleotide probes that detect quantitatively significant groups of butyrate-producing bacteria in human feces. Appl Environ Microbiol. 2003;69:4320-4324.
    • (2003) Appl Environ Microbiol , vol.69 , pp. 4320-4324
    • Hold, G.L.1    Schwiertz, A.2    Aminov, R.I.3
  • 42
    • 3242737791 scopus 로고    scopus 로고
    • Enhanced Escherichia coli adherence and invasion in Crohn's disease and colon cancer
    • Martin HM, Campbell BJ, Hart CA, et al. Enhanced Escherichia coli adherence and invasion in Crohn's disease and colon cancer. Gastroenterology. 2004;127:80-93.
    • (2004) Gastroenterology , vol.127 , pp. 80-93
    • Martin, H.M.1    Campbell, B.J.2    Hart, C.A.3
  • 43
    • 4143069158 scopus 로고    scopus 로고
    • High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease
    • Darfeuille-Michaud A, Boudeau J, Bulois P, et al. High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease. Gastroenterology. 2004;127:412-421.
    • (2004) Gastroenterology , vol.127 , pp. 412-421
    • Darfeuille-Michaud, A.1    Boudeau, J.2    Bulois, P.3
  • 44
    • 0018222160 scopus 로고
    • Influence of inflammatory bowel disease on intestinal microflora
    • Keighley MR, Arabi Y, Dimock F, et al. Influence of inflammatory bowel disease on intestinal microflora. Gut. 1978;19:1099-1104.
    • (1978) Gut , vol.19 , pp. 1099-1104
    • Keighley, M.R.1    Arabi, Y.2    Dimock, F.3
  • 45
    • 19244365532 scopus 로고    scopus 로고
    • High incidence of Crohn's disease in pre-menopausal women: Escherichia coli may be contributing
    • El-Tawil AM. High incidence of Crohn's disease in pre-menopausal women: Escherichia coli may be contributing. Int J Colorectal Dis. 2004;19:498.
    • (2004) Int J Colorectal Dis , vol.19 , pp. 498
    • El-Tawil, A.M.1
  • 46
    • 0036744155 scopus 로고    scopus 로고
    • Adherent-invasive Escherichia coli: A putative new E. coli pathotype associated with Crohn's disease
    • Darfeuille-Michaud A. Adherent-invasive Escherichia coli: a putative new E. coli pathotype associated with Crohn's disease. Int J Med Microbiol. 2002;292:185-193.
    • (2002) Int J Med Microbiol , vol.292 , pp. 185-193
    • Darfeuille-Michaud, A.1
  • 47
    • 0034873344 scopus 로고    scopus 로고
    • Adherent invasive Escherichia coli strains from patients with Crohn's disease survive and replicate within macrophages without inducing host cell death
    • Glasser AL, Boudeau J, Barnich N, et al. Adherent invasive Escherichia coli strains from patients with Crohn's disease survive and replicate within macrophages without inducing host cell death. Infect Immun. 2001;69:5529-5537.
    • (2001) Infect Immun , vol.69 , pp. 5529-5537
    • Glasser, A.L.1    Boudeau, J.2    Barnich, N.3
  • 48
    • 0032768352 scopus 로고    scopus 로고
    • Invasive ability of an Escherichia coli strain isolated from the ileal mucosa of a patient with Crohn's disease
    • Boudeau J, Glasser AL, Masseret E, et al. Invasive ability of an Escherichia coli strain isolated from the ileal mucosa of a patient with Crohn's disease. Infect Immun. 1999;67:4499-4509.
    • (1999) Infect Immun , vol.67 , pp. 4499-4509
    • Boudeau, J.1    Glasser, A.L.2    Masseret, E.3
  • 49
    • 0031758230 scopus 로고    scopus 로고
    • Presence of adherent Escherichia coli strains in ileal mucosa of patients with Crohn's disease
    • Darfeuille-Michaud A, Neut C, Barnich N, et al. Presence of adherent Escherichia coli strains in ileal mucosa of patients with Crohn's disease. Gastroenterology. 1998;115:1405-1413.
    • (1998) Gastroenterology , vol.115 , pp. 1405-1413
    • Darfeuille-Michaud, A.1    Neut, C.2    Barnich, N.3
  • 50
    • 0031055321 scopus 로고    scopus 로고
    • Escherichia coli O157: H7 infection mimicking Crohn's disease
    • Ilnyckyj A, Greenberg H, Bernstein CN. Escherichia coli O157: H7 infection mimicking Crohn's disease. Gastroenterology. 1997;112:995-999.
    • (1997) Gastroenterology , vol.112 , pp. 995-999
    • Ilnyckyj, A.1    Greenberg, H.2    Bernstein, C.N.3
  • 51
    • 2342646956 scopus 로고    scopus 로고
    • Bacterial flagellin is a dominant antigen in Crohn disease
    • Lodes MJ, Cong Y, Elson CO, et al. Bacterial flagellin is a dominant antigen in Crohn disease. J Clin Invest. 2004;113:1296-1306.
    • (2004) J Clin Invest , vol.113 , pp. 1296-1306
    • Lodes, M.J.1    Cong, Y.2    Elson, C.O.3


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