메뉴 건너뛰기




Volumn 112, Issue 2, 2015, Pages 232-237

IRAK signalling in cancer

Author keywords

Cancer; IRAK; Leukaemia; Myelodysplasia; NF B

Indexed keywords

BENZIMIDAZOLE PYRIDINE; GINSENOSIDE RB 1; IBRUTINIB; IMIDAZO[1,2 A]PYRIDINO PYRIDINE; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 2; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 3; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; MYELOID DIFFERENTIATION FACTOR 88; N ACYL 2 AMINOBENZIMIDAZOLE; PROTEIN SERINE THREONINE KINASE INHIBITOR; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT;

EID: 84922337316     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2014.513     Document Type: Short Survey
Times cited : (125)

References (43)
  • 9
    • 84920947218 scopus 로고    scopus 로고
    • Synergistic blockade of activated B-cell-like DLBCL proliferation with a selective inhibitor of IRAK4 in combination with inhibition of the B-cell receptor signaling network
    • abstract
    • Chaudhary D, Romero Dl WN, Greenwood Jr Robinson S, Shelley M, Morin M, Kapeller R, Westlin WF (2013) Synergistic blockade of activated B-cell-like DLBCL proliferation with a selective inhibitor of IRAK4 in combination with inhibition of the B-cell receptor signaling network [abstract]. Blood 122.
    • (2013) Blood , vol.122
    • Chaudhary, D.1    Romero, Dl.W.N.2    Greenwood, R.S.3    Shelley, M.4    Morin, M.5    Kapeller, R.6    Westlin, W.F.7
  • 10
    • 43249120917 scopus 로고    scopus 로고
    • Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptorand toll-like receptor-mediated Nf-KappaB activation
    • Conze DB, Wu CJ, Thomas JA, Landstrom A, Ashwell JD (2008) Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptorand toll-like receptor-mediated Nf-KappaB activation. Mol Cell Biol 28: 3538-3547.
    • (2008) Mol Cell Biol , vol.28 , pp. 3538-3547
    • Conze, D.B.1    Wu, C.J.2    Thomas, J.A.3    Landstrom, A.4    Ashwell, J.D.5
  • 11
    • 1842502927 scopus 로고    scopus 로고
    • Interleukin receptor-associated kinase (IRAK-4) deficiency associated with bacterial infections and failure to sustain antibody responses
    • Day N, Tangsinmankong N, Ochs H, Rucker R, Picard C, Casanova JL, Haraguchi S, Good R (2004) Interleukin receptor-associated kinase (IRAK-4) deficiency associated with bacterial infections and failure to sustain antibody responses. J Pediatr 144: 524-526.
    • (2004) J Pediatr , vol.144 , pp. 524-526
    • Day, N.1    Tangsinmankong, N.2    Ochs, H.3    Rucker, R.4    Picard, C.5    Casanova, J.L.6    Haraguchi, S.7    Good, R.8
  • 14
    • 61849140711 scopus 로고    scopus 로고
    • Infectious agents and lymphoma development: Molecular and clinical aspects
    • Ferreri AJ, Ernberg I, Copie-Bergman C (2009) Infectious agents and lymphoma development: molecular and clinical aspects. J Intern Med 265: 421-438.
    • (2009) J Intern Med , vol.265 , pp. 421-438
    • Ferreri, A.J.1    Ernberg, I.2    Copie-Bergman, C.3
  • 15
    • 10944228420 scopus 로고    scopus 로고
    • Irak1 serves as a novel regulator essential for lipopolysaccharide-induced interleukin-10 gene expression
    • Huang Y, Li T, Sane DC, Li L (2004) Irak1 serves as a novel regulator essential for lipopolysaccharide-induced interleukin-10 gene expression. J Biol Chem 279: 51697-51703.
    • (2004) J Biol Chem , vol.279 , pp. 51697-51703
    • Huang, Y.1    Li, T.2    Sane, D.C.3    Li, L.4
  • 16
    • 79959563146 scopus 로고    scopus 로고
    • Ginsenoside Rb1 and its metabolite compound K inhibit IRAK-1 activation - The key step of inflammation
    • Joh EH, Lee IA, Jung IH, Kim DH (2011) Ginsenoside Rb1 and its metabolite compound K inhibit IRAK-1 activation-the key step of inflammation. Biochem Pharmacol 82: 278-286.
    • (2011) Biochem Pharmacol , vol.82 , pp. 278-286
    • Joh, E.H.1    Lee, I.A.2    Jung, I.H.3    Kim, D.H.4
  • 19
    • 1242272100 scopus 로고    scopus 로고
    • Sequential autophosphorylation steps in the interleukin-1 receptor-associated kinase-1 regulate its availability as an adapter in interleukin-1 signaling
    • Kollewe C, Mackensen AC, Neumann D, Knop J, Cao P, Li S, Wesche H, Martin MU (2004) Sequential autophosphorylation steps in the interleukin-1 receptor-associated kinase-1 regulate its availability as an adapter in interleukin-1 signaling. J Biol Chem 279: 5227-5236.
    • (2004) J Biol Chem , vol.279 , pp. 5227-5236
    • Kollewe, C.1    Mackensen, A.C.2    Neumann, D.3    Knop, J.4    Cao, P.5    Li, S.6    Wesche, H.7    Martin, M.U.8
  • 20
    • 43649093749 scopus 로고    scopus 로고
    • IRAK-4 kinase activity-dependent and -independent regulation of lipopolysaccharide-inducible genes
    • Koziczak-Holbro M, Gluck A, Tschopp C, Mathison JC, Gram H (2008) IRAK-4 kinase activity-dependent and -independent regulation of lipopolysaccharide-inducible genes. Eur J Immunol 38: 788-796.
    • (2008) Eur J Immunol , vol.38 , pp. 788-796
    • Koziczak-Holbro, M.1    Gluck, A.2    Tschopp, C.3    Mathison, J.C.4    Gram, H.5
  • 21
    • 77953714711 scopus 로고    scopus 로고
    • Helical assembly in the Myd88-IRAK4-IRAK2 complex in TLR/IL-1R signalling
    • Lin SC, Lo YC, Wu H (2010) Helical assembly in the Myd88-IRAK4-IRAK2 complex in TLR/IL-1R signalling. Nature 465: 885-890.
    • (2010) Nature , vol.465 , pp. 885-890
    • Lin, S.C.1    Lo, Y.C.2    Wu, H.3
  • 22
    • 0033560731 scopus 로고    scopus 로고
    • Overexpression of an enzymically inactive interleukin-1-receptor-associated kinase activates nuclear factor-kappaB
    • Maschera B, Ray K, Burns K, Volpe F (1999) Overexpression of an enzymically inactive interleukin-1-receptor-associated kinase activates nuclear factor-kappaB. Biochem J 339(Pt 2): 227-231.
    • (1999) Biochem J , vol.339 , pp. 227-231
    • Maschera, B.1    Ray, K.2    Burns, K.3    Volpe, F.4
  • 23
    • 18944391904 scopus 로고    scopus 로고
    • Cutting edge: Expression of IL-1 receptor-associated kinase-4 (IRAK-4) proteins with mutations identified in a patient with recurrent bacterial infections alters normal IRAK-4 interaction with components of the IL-1 receptor complex
    • Medvedev AE, Thomas K, Awomoyi A, Kuhns DB, Gallin JI, Li X, Vogel SN (2005) Cutting edge: expression of IL-1 receptor-associated kinase-4 (IRAK-4) proteins with mutations identified in a patient with recurrent bacterial infections alters normal IRAK-4 interaction with components of the IL-1 receptor complex. J Immunol 174: 6587-6591.
    • (2005) J Immunol , vol.174 , pp. 6587-6591
    • Medvedev, A.E.1    Thomas, K.2    Awomoyi, A.3    Kuhns, D.B.4    Gallin, J.I.5    Li, X.6    Vogel, S.N.7
  • 26
    • 84883406297 scopus 로고    scopus 로고
    • Two phases of inflammatory mediator production defined by the study of IRAK2 and IRAK1 knock-in mice
    • Pauls E, Nanda SK, Smith H, Toth R, Arthur JS, Cohen P (2013) Two phases of inflammatory mediator production defined by the study of IRAK2 and IRAK1 knock-in mice. J Immunol 191: 2717-2730.
    • (2013) J Immunol , vol.191 , pp. 2717-2730
    • Pauls, E.1    Nanda, S.K.2    Smith, H.3    Toth, R.4    Arthur, J.S.5    Cohen, P.6
  • 28
    • 2942748292 scopus 로고    scopus 로고
    • IRAK4 kinase activity is redundant for interleukin-1 (IL-1) receptor-associated kinase phosphorylation and IL-1 responsiveness
    • Qin J, Jiang Z, Qian Y, Casanova JL, Li X (2004) IRAK4 kinase activity is redundant for interleukin-1 (IL-1) receptor-associated kinase phosphorylation and IL-1 responsiveness. J Biol Chem 279: 26748-26753.
    • (2004) J Biol Chem , vol.279 , pp. 26748-26753
    • Qin, J.1    Jiang, Z.2    Qian, Y.3    Casanova, J.L.4    Li, X.5
  • 30
    • 77950678935 scopus 로고    scopus 로고
    • Understanding kinase selectivity through energetic analysis of binding site waters
    • Robinson DD, Sherman W, Farid R (2010) Understanding kinase selectivity through energetic analysis of binding site waters. ChemMedChem 5: 618-627.
    • (2010) ChemMedChem , vol.5 , pp. 618-627
    • Robinson, D.D.1    Sherman, W.2    Farid, R.3
  • 33
    • 33748802777 scopus 로고    scopus 로고
    • Differential regulation of interleukin-1 receptor associated kinase 1 (IRAK1) splice variants
    • Su J, Richter K, Zhang C, Gu Q, Li L (2007) Differential regulation of interleukin-1 receptor associated kinase 1 (IRAK1) splice variants. Mol Immunol 44: 900-905.
    • (2007) Mol Immunol , vol.44 , pp. 900-905
    • Su, J.1    Richter, K.2    Zhang, C.3    Gu, Q.4    Li, L.5
  • 35
    • 73649112422 scopus 로고    scopus 로고
    • Tobacco smoke promotes lung tumorigenesis by triggering Ikkbeta- and JNK1-dependent inflammation
    • Takahashi H, Ogata H, Nishigaki R, Broide DH, Karin M (2010) Tobacco smoke promotes lung tumorigenesis by triggering Ikkbeta- and JNK1-dependent inflammation. Cancer Cell 17: 89-97.
    • (2010) Cancer Cell , vol.17 , pp. 89-97
    • Takahashi, H.1    Ogata, H.2    Nishigaki, R.3    Broide, D.H.4    Karin, M.5
  • 38
    • 33845231575 scopus 로고    scopus 로고
    • Crystal structures of IRAK-4 kinase in complex with inhibitors: A serine/threonine kinase with tyrosine as a gatekeeper
    • Wang Z, Liu J, Sudom A, Ayres M, Li S, Wesche H, Powers JP, Walker NP (2006) Crystal structures of IRAK-4 kinase in complex with inhibitors: a serine/threonine kinase with tyrosine as a gatekeeper. Structure 14: 1835-1844.
    • (2006) Structure , vol.14 , pp. 1835-1844
    • Wang, Z.1    Liu, J.2    Sudom, A.3    Ayres, M.4    Li, S.5    Wesche, H.6    Powers, J.P.7    Walker, N.P.8
  • 40
    • 34248587897 scopus 로고    scopus 로고
    • Loss of the innate immunity negative regulator IRAK-M leads to enhanced host immune defense against tumor growth
    • Xie Q, Gan L, Wang J, Wilson I, Li L (2007) Loss of the innate immunity negative regulator IRAK-M leads to enhanced host immune defense against tumor growth. Mol Immunol 44: 3453-3461.
    • (2007) Mol Immunol , vol.44 , pp. 3453-3461
    • Xie, Q.1    Gan, L.2    Wang, J.3    Wilson, I.4    Li, L.5
  • 41
    • 0030868909 scopus 로고    scopus 로고
    • The interleukin-1 receptor-associated kinase is degraded by proteasomes following its phosphorylation
    • Yamin TT, Miller DK (1997) The interleukin-1 receptor-associated kinase is degraded by proteasomes following its phosphorylation. J Biol Chem 272: 21540-21547.
    • (1997) J Biol Chem , vol.272 , pp. 21540-21547
    • Yamin, T.T.1    Miller, D.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.