Ginsenoside Rb1 and its metabolite compound K inhibit IRAK-1 activation - The key step of inflammation

Biochemical Pharmacology

Volumn 82, Issue 3, 2011, Pages 278-286

  Joh, Eun Ha ^a   Lee, In Ah ^a   Jung, Il Hoon ^a   Kim, Dong Hyun ^a  

^a Kyung Hee University   (South Korea)

Author keywords

Compound K; Ginsenoside Rb1; Interleukin 1 receptor associated kinase 1

Indexed keywords

COMPOUND K; CYCLOOXYGENASE 2; DRUG METABOLITE; GINSENOSIDE RB 1; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 2; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MYELOPEROXIDASE; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 4; TRINITROBENZENESULFONIC ACID; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; COLITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; DRUG POTENCY; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME INHIBITION; EXPERIMENTAL MODEL; GINSENG; HISTOPATHOLOGY; INFLAMMATION; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; COLITIS; ENZYME INHIBITORS; GINSENOSIDES; INFLAMMATION; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; MALE; MICE; MICE, INBRED ICR; MOLECULAR STRUCTURE; PANAX; TRINITROBENZENESULFONIC ACID;

EID: 79959563146     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.05.003     Document Type: Article

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