-
1
-
-
70350755818
-
Myelodysplastic syndromes
-
Tefferi A, Vardiman JW. Myelodysplastic syndromes. N Engl J Med 2009; 361: 1872-1885.
-
(2009)
N Engl J Med
, vol.361
, pp. 1872-1885
-
-
Tefferi, A.1
Vardiman, J.W.2
-
2
-
-
84887322071
-
Global H3K4me3 genome mapping reveals alterations of innate immunity signaling and overexpression of JMJD3 in human myelodysplastic syndrome CD34\+ cells
-
e-pub ahead of print 29 March 2013 doi:10.1038/leu.2013.91
-
Wei Y, Chen R, Dimicoli S, Bueso-Ramos C, Neuberg D, Pierce S et al. Global H3K4me3 genome mapping reveals alterations of innate immunity signaling and overexpression of JMJD3 in human myelodysplastic syndrome CD34\+ cells. Leukemia 2013; e-pub ahead of print 29 March 2013; doi:10.1038/leu.2013.91.
-
(2013)
Leukemia
-
-
Wei, Y.1
Chen, R.2
Dimicoli, S.3
Bueso-Ramos, C.4
Neuberg, D.5
Pierce, S.6
-
3
-
-
32944464648
-
Pathogen recognition and innate immunity
-
DOI 10.1016/j.cell.2006.02.015, PII S0092867406001905
-
Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell 2006; 124: 783-801. (Pubitemid 43261452)
-
(2006)
Cell
, vol.124
, Issue.4
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
4
-
-
34548644772
-
The Histone H3 Lysine-27 Demethylase Jmjd3 Links Inflammation to Inhibition of Polycomb-Mediated Gene Silencing
-
DOI 10.1016/j.cell.2007.08.019, PII S0092867407010823
-
De Santa F, Totaro MG, Prosperini E, Notarbartolo S, Testa G, Natoli G. The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycombmediated gene silencing. Cell 2007; 130: 1083-1094. (Pubitemid 47410272)
-
(2007)
Cell
, vol.130
, Issue.6
, pp. 1083-1094
-
-
De Santa, F.1
Totaro, M.G.2
Prosperini, E.3
Notarbartolo, S.4
Testa, G.5
Natoli, G.6
-
5
-
-
67649884743
-
Fast and accurate short read alignment with Burrows-Wheeler transform
-
Li H, Durbin R. Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 2009; 25: 1754-1760.
-
(2009)
Bioinformatics
, vol.25
, pp. 1754-1760
-
-
Li, H.1
Durbin, R.2
-
6
-
-
77956295988
-
The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
-
McKenna A, Hanna M, Banks E, Sivachenko A, Cibulskis K, Kernytsky A et al. The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. Genome Res 2010; 20: 1297-1303.
-
(2010)
Genome Res
, vol.20
, pp. 1297-1303
-
-
McKenna, A.1
Hanna, M.2
Banks, E.3
Sivachenko, A.4
Cibulskis, K.5
Kernytsky, A.6
-
7
-
-
71749118913
-
Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer
-
Kang JY, Nan X, Jin MS, Youn SJ, Ryu YH, Mah S et al. Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer. Immunity 2009; 31: 873-884.
-
(2009)
Immunity
, vol.31
, pp. 873-884
-
-
Kang, J.Y.1
Nan, X.2
Jin, M.S.3
Youn, S.J.4
Ryu, Y.H.5
Mah, S.6
-
8
-
-
0036644042
-
Cutting edge: Role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins
-
Takeuchi O, Sato S, Horiuchi T, Hoshino K, Takeda K, Dong Z et al. Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins. J Immunol 2002; 169: 10-14. (Pubitemid 34686113)
-
(2002)
Journal of Immunology
, vol.169
, Issue.1
, pp. 10-14
-
-
Takeuchi, O.1
Sato, S.2
Horiuchi, T.3
Hoshino, K.4
Takeda, K.5
Dong, Z.6
Modlin, R.L.7
Akira, S.8
-
9
-
-
34447318082
-
Characterization and investigation of single nucleotide polymorphisms and a novel TLR2 mutation in the human TLR2 gene
-
DOI 10.1093/hmg/ddm070
-
Merx S, Neumaier M, Wagner H, Kirschning CJ, Ahmad-Nejad P. Characterization and investigation of single nucleotide polymorphisms and a novel TLR2 mutation in the human TLR2 gene. Hum Mol Genet 2007; 16: 1225-1232. (Pubitemid 47062718)
-
(2007)
Human Molecular Genetics
, vol.16
, Issue.10
, pp. 1225-1232
-
-
Merx, S.1
Neumaier, M.2
Wagner, H.3
Kirschning, C.J.4
Ahmad-Nejad, P.5
-
10
-
-
0037292275
-
Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members
-
DOI 10.1016/S1097-2765(03)00053-4
-
Janssens S, Beyaert R. Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members. Mol Cell 2003; 11: 293-302. (Pubitemid 36293825)
-
(2003)
Molecular Cell
, vol.11
, Issue.2
, pp. 293-302
-
-
Janssens, S.1
Beyaert, R.2
-
11
-
-
43249120917
-
Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-κB activation
-
DOI 10.1128/MCB.02098-07
-
Conze DB, Wu CJ, Thomas JA, Landstrom A, Ashwell JD. Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor-and toll-like receptor-mediated NF-kappaB activation. Mol Cell Biol 2008; 28: 3538-3547. (Pubitemid 351657114)
-
(2008)
Molecular and Cellular Biology
, vol.28
, Issue.10
, pp. 3538-3547
-
-
Conze, D.B.1
Wu, C.-J.2
Thomas, J.A.3
Landstrom, A.4
Ashwell, J.D.5
-
12
-
-
78549250108
-
Recurrent expression signatures of cytokines and chemokines are present and are independently prognostic in acute myelogenous leukemia and myelodysplasia
-
Kornblau SM, McCue D, Singh N, Chen W, Estrov Z, Coombes KR. Recurrent expression signatures of cytokines and chemokines are present and are independently prognostic in acute myelogenous leukemia and myelodysplasia. Blood 2010; 116: 4251-4261.
-
(2010)
Blood
, vol.116
, pp. 4251-4261
-
-
Kornblau, S.M.1
McCue, D.2
Singh, N.3
Chen, W.4
Estrov, Z.5
Coombes, K.R.6
-
13
-
-
35348871316
-
+ DC capable of inducing a Th1-type response
-
DOI 10.1002/eji.200737112
-
Sioud M, Floisand Y. TLR agonists induce the differentiation of human bone marrow CD34\+ progenitors into CD11c\+ CD80/86\+ DC capable of inducing a Th1-type response. Eur J Immunol 2007; 37: 2834-2846. (Pubitemid 47578303)
-
(2007)
European Journal of Immunology
, vol.37
, Issue.10
, pp. 2834-2846
-
-
Sioud, M.1
Floisand, Y.2
-
14
-
-
73849121794
-
Identification of miR-145 and miR-146a as mediators of the 5qsyndrome phenotype
-
Starczynowski DT, Kuchenbauer F, Argiropoulos B, Sung S, Morin R, Muranyi A et al. Identification of miR-145 and miR-146a as mediators of the 5qsyndrome phenotype. Nat Med 2010; 16: 49-58.
-
(2010)
Nat Med
, vol.16
, pp. 49-58
-
-
Starczynowski, D.T.1
Kuchenbauer, F.2
Argiropoulos, B.3
Sung, S.4
Morin, R.5
Muranyi, A.6
-
15
-
-
84856709581
-
Deregulation of microRNAs in myelodysplastic syndrome
-
Rhyasen GW, Starczynowski DT. Deregulation of microRNAs in myelodysplastic syndrome. Leukemia 2012; 26: 13-22.
-
(2012)
Leukemia
, vol.26
, pp. 13-22
-
-
Rhyasen, G.W.1
Starczynowski, D.T.2
-
16
-
-
33744978765
-
Toll-like Receptors on Hematopoietic Progenitor Cells Stimulate Innate Immune System Replenishment
-
DOI 10.1016/j.immuni.2006.04.008, PII S1074761306002664
-
Nagai Y, Garrett KP, Ohta S, Bahrun U, Kouro T, Akira S et al. Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment. Immunity 2006; 24: 801-812. (Pubitemid 43867369)
-
(2006)
Immunity
, vol.24
, Issue.6
, pp. 801-812
-
-
Nagai, Y.1
Garrett, K.P.2
Ohta, S.3
Bahrun, U.4
Kouro, T.5
Akira, S.6
Takatsu, K.7
Kincade, P.W.8
-
17
-
-
79955530513
-
Chronic exposure to a TLR ligand injures hematopoietic stem cells
-
Esplin BL, Shimazu T, Welner RS, Garrett KP, Nie L, Zhang Q et al. Chronic exposure to a TLR ligand injures hematopoietic stem cells. J Immunol 2011; 186: 5367-5375.
-
(2011)
J Immunol
, vol.186
, pp. 5367-5375
-
-
Esplin, B.L.1
Shimazu, T.2
Welner, R.S.3
Garrett, K.P.4
Nie, L.5
Zhang, Q.6
-
18
-
-
70450237721
-
The TLR1/2 agonist PAM(3)CSK(4) instructs commitment of human hematopoietic stem cells to a myeloid cell fate
-
De Luca K, Frances-Duvert V, Asensio MJ, Ihsani R, Debien E, Taillardet M et al. The TLR1/2 agonist PAM(3)CSK(4) instructs commitment of human hematopoietic stem cells to a myeloid cell fate. Leukemia 2009; 23: 2063-2074.
-
(2009)
Leukemia
, vol.23
, pp. 2063-2074
-
-
De Luca, K.1
Frances-Duvert, V.2
Asensio, M.J.3
Ihsani, R.4
Debien, E.5
Taillardet, M.6
-
20
-
-
79953066407
-
HMGB1 is a therapeutic target for sterile inflammation and infection
-
Andersson U, Tracey KJ. HMGB1 is a therapeutic target for sterile inflammation and infection. Annual Rev Immunol 2011; 29: 139-162.
-
(2011)
Annual Rev Immunol
, vol.29
, pp. 139-162
-
-
Andersson, U.1
Tracey, K.J.2
-
21
-
-
77949902065
-
Autosomal dominant and sporadic monocytopenia with susceptibility to mycobacteria, fungi, papillomaviruses, and myelodysplasia
-
Vinh DC, Patel SY, Uzel G, Anderson VL, Freeman AF, Olivier KN et al. Autosomal dominant and sporadic monocytopenia with susceptibility to mycobacteria, fungi, papillomaviruses, and myelodysplasia. Blood 2010; 115: 1519-1529.
-
(2010)
Blood
, vol.115
, pp. 1519-1529
-
-
Vinh, D.C.1
Patel, S.Y.2
Uzel, G.3
Anderson, V.L.4
Freeman, A.F.5
Olivier, K.N.6
-
22
-
-
84867605321
-
STAT3-driven upregulation of TLR2 promotes gastric tumorigenesis independent of tumor inflammation
-
Tye H, Kennedy CL, Najdovska M, McLeod L, McCormack W, Hughes N et al. STAT3-driven upregulation of TLR2 promotes gastric tumorigenesis independent of tumor inflammation. Cancer Cell 2012; 22: 466-478.
-
(2012)
Cancer Cell
, vol.22
, pp. 466-478
-
-
Tye, H.1
Kennedy, C.L.2
Najdovska, M.3
McLeod, L.4
McCormack, W.5
Hughes, N.6
-
23
-
-
33947255107
-
Toll-like receptor-4 is up-regulated in hematopoietic progenitor cells and contributes to increased apoptosis in myelodysplastic syndromes
-
DOI 10.1158/1078-0432.CCR-06-2108
-
Maratheftis CI, Andreakos E, Moutsopoulos HM, Voulgarelis M. Toll-like receptor-4 is up-regulated in hematopoietic progenitor cells and contributes to increased apoptosis in myelodysplastic syndromes. Clin Cancer Res 2007; 13: 1154-1160. (Pubitemid 46424055)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.4
, pp. 1154-1160
-
-
Maratheftis, C.I.1
Andreakos, E.2
Moutsopoulos, H.M.3
Voulgarelis, M.4
-
24
-
-
0043163751
-
Severe and selective deficiency of interferon-γ-producing invariant natural killer T cells in patients with myelodysplastic syndromes
-
DOI 10.1046/j.1365-2141.2003.04465.x
-
Fujii S, Shimizu K, Klimek V, Geller MD, Nimer SD, Dhodapkar MV. Severe and selective deficiency of interferon-gamma-producing invariant natural killer T cells in patients with myelodysplastic syndromes. Br J Haematol 2003; 122: 617-622. (Pubitemid 36995216)
-
(2003)
British Journal of Haematology
, vol.122
, Issue.4
, pp. 617-622
-
-
Fujii, S.-I.1
Shimizu, K.2
Klimek, V.3
Geller, M.D.4
Nimer, S.D.5
Dhodapkar, M.V.6
-
25
-
-
77949423620
-
Testing the NKT cell hypothesis in lenalidomide-treated myelodysplastic syndrome patients
-
Chan AC, Neeson P, Leeansyah E, Tainton K, Quach H, Prince HM et al. Testing the NKT cell hypothesis in lenalidomide-treated myelodysplastic syndrome patients. Leukemia 2010; 24: 592-600.
-
(2010)
Leukemia
, vol.24
, pp. 592-600
-
-
Chan, A.C.1
Neeson, P.2
Leeansyah, E.3
Tainton, K.4
Quach, H.5
Prince, H.M.6
-
26
-
-
79751536458
-
Inflammatory signals regulate hematopoietic stem cells
-
Baldridge MT, King KY, Goodell MA. Inflammatory signals regulate hematopoietic stem cells. Trends Immunol 2011; 32: 57-65.
-
(2011)
Trends Immunol
, vol.32
, pp. 57-65
-
-
Baldridge, M.T.1
King, K.Y.2
Goodell, M.A.3
-
27
-
-
84857738200
-
P38 MAPK inhibition suppresses the TLR-hypersensitive phenotype in FANCC-and FANCAdeficient mononuclear phagocytes
-
Anur P, Yates J, Garbati MR, Vanderwerf S, Keeble W, Rathbun K et al. p38 MAPK inhibition suppresses the TLR-hypersensitive phenotype in FANCC-and FANCAdeficient mononuclear phagocytes. Blood 2012; 119: 1992-2002.
-
(2012)
Blood
, vol.119
, pp. 1992-2002
-
-
Anur, P.1
Yates, J.2
Garbati, M.R.3
Vanderwerf, S.4
Keeble, W.5
Rathbun, K.6
-
28
-
-
73949118736
-
TLR8-dependent TNF-(alpha) overexpression in Fanconi anemia group C cells
-
Vanderwerf SM, Svahn J, Olson S, Rathbun RK, Harrington C, Yates J et al. TLR8-dependent TNF-(alpha) overexpression in Fanconi anemia group C cells. Blood 2009; 114: 5290-5298.
-
(2009)
Blood
, vol.114
, pp. 5290-5298
-
-
Vanderwerf, S.M.1
Svahn, J.2
Olson, S.3
Rathbun, R.K.4
Harrington, C.5
Yates, J.6
-
29
-
-
84877836774
-
Toll-like receptor 6 plays an important role in host innate resistance to Brucella abortus infection in mice
-
de Almeida LA, Macedo GC, Marinho FA, Gomes MT, Corsetti PP, Silva AM et al. Toll-like receptor 6 plays an important role in host innate resistance to Brucella abortus infection in mice. Infect Immun 2013; 81: 1654-1662.
-
(2013)
Infect Immun
, vol.81
, pp. 1654-1662
-
-
De Almeida, L.A.1
MacEdo, G.C.2
Marinho, F.A.3
Gomes, M.T.4
Corsetti, P.P.5
Silva, A.M.6
|