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Volumn 24, Issue 1, 2013, Pages 90-104

Targeting IRAK1 as a Therapeutic Approach for Myelodysplastic Syndrome

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; DOXORUBICIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1 INHIBITOR; NAVITOCLAX; PROTEIN BCL 2; PROTEIN SERINE THREONINE KINASE INHIBITOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG;

EID: 84880002232     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccr.2013.05.006     Document Type: Article
Times cited : (166)

References (45)
  • 4
    • 77958038475 scopus 로고    scopus 로고
    • NF-κB as a potential therapeutic target in myelodysplastic syndromes and acute myeloid leukemia
    • Breccia M., Alimena G. NF-κB as a potential therapeutic target in myelodysplastic syndromes and acute myeloid leukemia. Expert Opin. Ther. Targets 2010, 14:1157-1176.
    • (2010) Expert Opin. Ther. Targets , vol.14 , pp. 1157-1176
    • Breccia, M.1    Alimena, G.2
  • 5
    • 33746882054 scopus 로고    scopus 로고
    • Gene expression profiling of acute myeloid leukemia with translocation t(8;16)(p11;p13) and MYST3-CREBBP rearrangement reveals a distinctive signature with a specific pattern of HOX gene expression
    • Camós M., Esteve J., Jares P., Colomer D., Rozman M., Villamor N., Costa D., Carrió A., Nomdedéu J., Montserrat E., Campo E. Gene expression profiling of acute myeloid leukemia with translocation t(8;16)(p11;p13) and MYST3-CREBBP rearrangement reveals a distinctive signature with a specific pattern of HOX gene expression. Cancer Res. 2006, 66:6947-6954.
    • (2006) Cancer Res. , vol.66 , pp. 6947-6954
    • Camós, M.1    Esteve, J.2    Jares, P.3    Colomer, D.4    Rozman, M.5    Villamor, N.6    Costa, D.7    Carrió, A.8    Nomdedéu, J.9    Montserrat, E.10    Campo, E.11
  • 6
    • 10244227886 scopus 로고    scopus 로고
    • Distinctive gene expression profiles of CD34 cells from patients with myelodysplastic syndrome characterized by specific chromosomal abnormalities
    • Chen G., Zeng W., Miyazato A., Billings E., Maciejewski J.P., Kajigaya S., Sloand E.M., Young N.S. Distinctive gene expression profiles of CD34 cells from patients with myelodysplastic syndrome characterized by specific chromosomal abnormalities. Blood 2004, 104:4210-4218.
    • (2004) Blood , vol.104 , pp. 4210-4218
    • Chen, G.1    Zeng, W.2    Miyazato, A.3    Billings, E.4    Maciejewski, J.P.5    Kajigaya, S.6    Sloand, E.M.7    Young, N.S.8
  • 7
    • 67849130563 scopus 로고    scopus 로고
    • ToppGene Suite for gene list enrichment analysis and candidate gene prioritization
    • Web Server issue
    • Chen J., Bardes E.E., Aronow B.J., Jegga A.G. ToppGene Suite for gene list enrichment analysis and candidate gene prioritization. Nucleic Acids Res. 2009, 37(Web Server issue):W305-W311.
    • (2009) Nucleic Acids Res. , vol.37
    • Chen, J.1    Bardes, E.E.2    Aronow, B.J.3    Jegga, A.G.4
  • 8
    • 43249120917 scopus 로고    scopus 로고
    • Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activation
    • Conze D.B., Wu C.J., Thomas J.A., Landstrom A., Ashwell J.D. Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activation. Mol. Cell. Biol. 2008, 28:3538-3547.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 3538-3547
    • Conze, D.B.1    Wu, C.J.2    Thomas, J.A.3    Landstrom, A.4    Ashwell, J.D.5
  • 10
    • 84880016154 scopus 로고    scopus 로고
    • March. IRAK modulators for treating an inflammatory condition, cell proliferation disorder, immune disorder. U.S. patent WO/2008/030579.
    • Durand-Reville, T., Jewell, C., Hammond, C., and Chin, D. March 2008. IRAK modulators for treating an inflammatory condition, cell proliferation disorder, immune disorder. U.S. patent WO/2008/030579.
    • (2008)
    • Durand-Reville, T.1    Jewell, C.2    Hammond, C.3    Chin, D.4
  • 11
    • 77950540879 scopus 로고    scopus 로고
    • Preface. The biology and treatment of myelodysplastic syndrome
    • Ebert B.L. Preface. The biology and treatment of myelodysplastic syndrome. Hematol. Oncol. Clin. North Am. 2010, 24:xiii-xvi.
    • (2010) Hematol. Oncol. Clin. North Am. , vol.24 , pp. 13-16
    • Ebert, B.L.1
  • 12
    • 84864495501 scopus 로고    scopus 로고
    • Cytotoxic effects of bortezomib in myelodysplastic syndrome/acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1
    • Fang J., Rhyasen G., Bolanos L., Rasch C., Varney M., Wunderlich M., Goyama S., Jansen G., Cloos J., Rigolino C., et al. Cytotoxic effects of bortezomib in myelodysplastic syndrome/acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1. Blood 2012, 120:858-867.
    • (2012) Blood , vol.120 , pp. 858-867
    • Fang, J.1    Rhyasen, G.2    Bolanos, L.3    Rasch, C.4    Varney, M.5    Wunderlich, M.6    Goyama, S.7    Jansen, G.8    Cloos, J.9    Rigolino, C.10
  • 13
    • 78049431237 scopus 로고    scopus 로고
    • The interleukin-1 receptor-associated kinases: critical regulators of innate immune signalling
    • Flannery S., Bowie A.G. The interleukin-1 receptor-associated kinases: critical regulators of innate immune signalling. Biochem. Pharmacol. 2011, 80:1981-1991.
    • (2011) Biochem. Pharmacol. , vol.80 , pp. 1981-1991
    • Flannery, S.1    Bowie, A.G.2
  • 14
    • 38949123096 scopus 로고    scopus 로고
    • Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML
    • Gondek L.P., Tiu R., O'Keefe C.L., Sekeres M.A., Theil K.S., Maciejewski J.P. Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML. Blood 2008, 111:1534-1542.
    • (2008) Blood , vol.111 , pp. 1534-1542
    • Gondek, L.P.1    Tiu, R.2    O'Keefe, C.L.3    Sekeres, M.A.4    Theil, K.S.5    Maciejewski, J.P.6
  • 15
    • 77954323523 scopus 로고    scopus 로고
    • Current therapeutic approaches for patients with myelodysplastic syndromes
    • Greenberg P.L. Current therapeutic approaches for patients with myelodysplastic syndromes. Br. J. Haematol. 2010, 150:131-143.
    • (2010) Br. J. Haematol. , vol.150 , pp. 131-143
    • Greenberg, P.L.1
  • 17
    • 0037111773 scopus 로고    scopus 로고
    • Characterization of gene expression of CD34+ cells from normal and myelodysplastic bone marrow
    • Hofmann W.K., de Vos S., Komor M., Hoelzer D., Wachsman W., Koeffler H.P. Characterization of gene expression of CD34+ cells from normal and myelodysplastic bone marrow. Blood 2002, 100:3553-3560.
    • (2002) Blood , vol.100 , pp. 3553-3560
    • Hofmann, W.K.1    de Vos, S.2    Komor, M.3    Hoelzer, D.4    Wachsman, W.5    Koeffler, H.P.6
  • 18
    • 1242272100 scopus 로고    scopus 로고
    • Sequential autophosphorylation steps in the interleukin-1 receptor-associated kinase-1 regulate its availability as an adapter in interleukin-1 signaling
    • Kollewe C., Mackensen A.C., Neumann D., Knop J., Cao P., Li S., Wesche H., Martin M.U. Sequential autophosphorylation steps in the interleukin-1 receptor-associated kinase-1 regulate its availability as an adapter in interleukin-1 signaling. J.Biol. Chem. 2004, 279:5227-5236.
    • (2004) J.Biol. Chem. , vol.279 , pp. 5227-5236
    • Kollewe, C.1    Mackensen, A.C.2    Neumann, D.3    Knop, J.4    Cao, P.5    Li, S.6    Wesche, H.7    Martin, M.U.8
  • 19
    • 79960709287 scopus 로고    scopus 로고
    • Chronic immune stimulation might act as a trigger for the development of acute myeloid leukemia or myelodysplastic syndromes
    • Kristinsson S.Y., Björkholm M., Hultcrantz M., Derolf A.R., Landgren O., Goldin L.R. Chronic immune stimulation might act as a trigger for the development of acute myeloid leukemia or myelodysplastic syndromes. J.Clin. Oncol. 2011, 29:2897-2903.
    • (2011) J.Clin. Oncol. , vol.29 , pp. 2897-2903
    • Kristinsson, S.Y.1    Björkholm, M.2    Hultcrantz, M.3    Derolf, A.R.4    Landgren, O.5    Goldin, L.R.6
  • 20
    • 77956422816 scopus 로고    scopus 로고
    • Limited engraftment of low-risk myelodysplastic syndrome cells in NOD/SCID gamma-C chain knockout mice
    • Martin M.G., Welch J.S., Uy G.L., Fehniger T.A., Kulkarni S., Duncavage E.J., Walter M.J. Limited engraftment of low-risk myelodysplastic syndrome cells in NOD/SCID gamma-C chain knockout mice. Leukemia 2011, 24:1662-1664.
    • (2011) Leukemia , vol.24 , pp. 1662-1664
    • Martin, M.G.1    Welch, J.S.2    Uy, G.L.3    Fehniger, T.A.4    Kulkarni, S.5    Duncavage, E.J.6    Walter, M.J.7
  • 23
    • 46749151451 scopus 로고    scopus 로고
    • Myelodysplastic syndromes
    • Nimer S.D. Myelodysplastic syndromes. Blood 2008, 111:4841-4851.
    • (2008) Blood , vol.111 , pp. 4841-4851
    • Nimer, S.D.1
  • 28
    • 78649916901 scopus 로고    scopus 로고
    • Are we nearer to curing patients with MDS?
    • Sekeres M.A. Are we nearer to curing patients with MDS?. Best Pract. Res. Clin. Haematol. 2010, 23:481-487.
    • (2010) Best Pract. Res. Clin. Haematol. , vol.23 , pp. 481-487
    • Sekeres, M.A.1
  • 29
    • 77950526605 scopus 로고    scopus 로고
    • The epidemiology of myelodysplastic syndromes
    • Sekeres M.A. The epidemiology of myelodysplastic syndromes. Hematol. Oncol. Clin. North Am. 2010, 24:287-294.
    • (2010) Hematol. Oncol. Clin. North Am. , vol.24 , pp. 287-294
    • Sekeres, M.A.1
  • 36
    • 33747608638 scopus 로고    scopus 로고
    • NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
    • Taganov K.D., Boldin M.P., Chang K.J., Baltimore D. NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc. Natl. Acad. Sci. USA 2006, 103:12481-12486.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 12481-12486
    • Taganov, K.D.1    Boldin, M.P.2    Chang, K.J.3    Baltimore, D.4
  • 38
    • 48549092932 scopus 로고    scopus 로고
    • Molecular profile of the BCL2 family of the apoptosis related genes in breast cancer cells after treatment with cytotoxic/cytostatic drugs
    • Thomadaki H., Scorilas A. Molecular profile of the BCL2 family of the apoptosis related genes in breast cancer cells after treatment with cytotoxic/cytostatic drugs. Connect. Tissue Res. 2008, 49:261-264.
    • (2008) Connect. Tissue Res. , vol.49 , pp. 261-264
    • Thomadaki, H.1    Scorilas, A.2
  • 39
    • 0028887065 scopus 로고
    • A novel factor-dependent human myelodysplastic cell line, MDS92, contains haemopoietic cells of several lineages
    • Tohyama K., Tohyama Y., Nakayama T., Ueda T., Nakamura T., Yoshida Y. A novel factor-dependent human myelodysplastic cell line, MDS92, contains haemopoietic cells of several lineages. Br. J. Haematol. 1995, 91:795-799.
    • (1995) Br. J. Haematol. , vol.91 , pp. 795-799
    • Tohyama, K.1    Tohyama, Y.2    Nakayama, T.3    Ueda, T.4    Nakamura, T.5    Yoshida, Y.6
  • 41
    • 77957162079 scopus 로고    scopus 로고
    • A distinct expression of various gene subsets in CD34+ cells from patients with early and advanced myelodysplastic syndrome
    • Vasikova A., Belickova M., Budinska E., Cermak J. A distinct expression of various gene subsets in CD34+ cells from patients with early and advanced myelodysplastic syndrome. Leuk. Res. 2010, 34:1566-1572.
    • (2010) Leuk. Res. , vol.34 , pp. 1566-1572
    • Vasikova, A.1    Belickova, M.2    Budinska, E.3    Cermak, J.4
  • 43
    • 77958013367 scopus 로고    scopus 로고
    • AML xenograft efficiency is significantly improved in NOD/SCID-IL2RG mice constitutively expressing human SCF, GM-CSF and IL-3
    • Wunderlich M., Chou F.S., Link K.A., Mizukawa B., Perry R.L., Carroll M., Mulloy J.C. AML xenograft efficiency is significantly improved in NOD/SCID-IL2RG mice constitutively expressing human SCF, GM-CSF and IL-3. Leukemia 2010, 24:1785-1788.
    • (2010) Leukemia , vol.24 , pp. 1785-1788
    • Wunderlich, M.1    Chou, F.S.2    Link, K.A.3    Mizukawa, B.4    Perry, R.L.5    Carroll, M.6    Mulloy, J.C.7
  • 44
    • 80054042211 scopus 로고    scopus 로고
    • Interleukin-1 receptor associated kinases-1/4 inhibition protects against acute hypoxia/ischemia-induced neuronal injury invivo and invitro
    • Yang Y.F., Chen Z., Hu S.L., Hu J., Li B., Li J.T., Wei L.J., Qian Z.M., Lin J.K., Feng H., Zhu G. Interleukin-1 receptor associated kinases-1/4 inhibition protects against acute hypoxia/ischemia-induced neuronal injury invivo and invitro. Neuroscience 2011, 196:25-34.
    • (2011) Neuroscience , vol.196 , pp. 25-34
    • Yang, Y.F.1    Chen, Z.2    Hu, S.L.3    Hu, J.4    Li, B.5    Li, J.T.6    Wei, L.J.7    Qian, Z.M.8    Lin, J.K.9    Feng, H.10    Zhu, G.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.