Cyclin D1 induction of dicer governs microRNA processing and expression in breast cancer

Nature Communications

Volumn 4, Issue , 2013, Pages

  Yu, Zuoren ^a,b,c   Wang, Liping ^a,b   Wang, Chenguang ^a,b   Ju, Xiaoming ^a,b   Wang, Min ^a,b   Chen, Ke ^a,b   Loro, Emanuele ^a,b   Li, Zhiping ^a,b   Zhang, Yuzhen ^c   Wu, Kongming ^a,b,e   Casimiro, Mathew C ^a,b   Gormley, Michael ^a,b   Ertel, Adam ^a,b   Fortina, Paolo ^a,b   Chen, Yihan ^c   Tozeren, Aydin ^b,d   Liu, Zhongmin ^c   Pestell, Richard G ^a,b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

^d DREXEL UNIVERSITY   (United States)

^e HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE; DICER; HISTONE; HISTONE H3; LYSINE; MICRORNA; RNA PRECURSOR;

CANCER; CORRELATION; ENZYME ACTIVITY; GENE EXPRESSION; HEALTH CARE; HUMAN GEOGRAPHY; RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOGENESIS; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; HETEROCHROMATIN; HISTONE METHYLATION; HISTONE MODIFICATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN TARGETING; RNA PROCESSING; TRANSCRIPTION REGULATION;

ANIMALS; BREAST NEOPLASMS; CELL MOVEMENT; CELL PROLIFERATION; CYCLIN D1; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HCT116 CELLS; HISTONES; HUMANS; MAMMARY NEOPLASMS, EXPERIMENTAL; MCF-7 CELLS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICRORNAS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RIBONUCLEASE III;

EID: 84889256981     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms3812     Document Type: Article

References (37)

1. Bartel, D. P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116, 281-297 (2004).
2. Yi, R., Qin, Y., Macara, I. G. & Cullen, B. R. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev. 17, 3011-3016 (2003). (Pubitemid 38040764)
3. Yu, Z. et al. (2008A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation. J. Cell Biol. 182, 509-517 (2008).
4. Lund, E., Sheets, M. D., Imboden, S. B. & Dahlberg, J. E. (2011Limiting Ago protein restricts RNAi and microRNA biogenesis during early development in Xenopus laevis. Genes Dev. 25, 1121-1131 (2011).
5. Chen, K. & Rajewsky, N. Deep conservation of microRNA-target relationships and 30UTR motifs in vertebrates, flies, and nematodes. Cold Spring Harb. Symp. Quant. Biol. 71, 149-156 (2006).
6. Tili, E. et al. miRNAs and their potential for use against cancer and other diseases. Future Oncol. 3, 521-537 (2007). (Pubitemid 47595862)
7. Gangaraju, V. K. & Lin, H. MicroRNAs: key regulators of stem cells. Nat. Rev. Mol. Cell Biol. 10, 116-125 (2009).
8. Lipchina, I. et al. Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response. Genes Dev. 25, 2173-2186 (2011).
9. Rissland, O. S., Hong, S. J. & Bartel, D. P. MicroRNA destabilization enables dynamic regulation of the miR-16 family in response to cell-cycle changes. Mol. Cell 43, 993-1004 (2011).
10. Png, K. J. et al. MicroRNA-335 inhibits tumor reinitiation and is silenced through genetic and epigenetic mechanisms in human breast cancer. Genes Dev. 25, 226-231 (2011).
11. Hutvagner, G. et al. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 293, 834-838 (2001). (Pubitemid 32743968)
12. Paddison, P. J., Caudy, A. A., Bernstein, E., Hannon, G. J. & Conklin, D. S. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev. 16, 948-958 (2002). (Pubitemid 34408544)
13. Hatfield, S. D. et al. Stem cell division is regulated by the microRNA pathway. Nature 435, 974-978 (2005). (Pubitemid 40896325)
14. Levy, C. et al. Lineage-specific transcriptional regulation of DICER by MITF in melanocytes. Cell 141, 994-1005 (2010).
15. Teta, M. et al. Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin. Development 139, 1405-1416 (2012).
16. Kato, J., Matsushime, H., Hiebert, S. W., Ewen, M. E. & Sherr, C. J. Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4. Genes Dev. 7, 331-342 (1993). (Pubitemid 23139228)
17. Wang, C. et al. Cyclin D1 repression of nuclear respiratory factor 1 integrates nuclear DNA synthesis and mitochondrial function. Proc Natl Acad Sci USA 103, 11567-11572 (2006). (Pubitemid 44182492)
18. Fu, M. et al. Cyclin D1 represses p300 transactivation through a cyclindependent kinase-independent mechanism. J. Biol. Chem. 280, 29728-29742 (2005). (Pubitemid 41177050)
19. Casimiro, M. C. et al. ChIP sequencing of cyclin D1 reveals a transcriptional role in chromosomal instability in mice. J. Clin. Invest. 122, 833-843 (2012).
20. Fu, M. et al. Cyclin D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitment. J. Biol. Chem. 208, 16934-16941 (2005). (Pubitemid 41389153)
21. Fu, M., Wang, C., Li, Z., Sakamaki, T. & Pestell, R. G. Minireview: Cyclin D1: normal and abnormal functions. Endocrinology 145, 5439-5447 (2004). (Pubitemid 39564581)
22. Yu, Z. et al. microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling. Proc. Natl Acad. Sci. USA 107, 8231-8236 (2010).
23. Han, J. et al. The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev. 18, 3016-3027 (2004). (Pubitemid 39658171)
24. Cummins, J. M. et al. The colorectal microRNAome. Proc. Natl Acad. Sci. USA 103, 3687-3692 (2006). (Pubitemid 43376616)
25. Benetti, R. et al. A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases. Nat. Struct. Mol. Biol. 15, 268-279 (2008). (Pubitemid 351654050)
26. Kanellopoulou, C. et al. Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes Dev. 19, 489-501 (2005). (Pubitemid 40256280)
27. Kumar, M. S., Lu, J., Mercer, K. L., Golub, T. R. & Jacks, T. Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat. Genet 39, 673-677 (2007). (Pubitemid 46676103)
28. Zhang, N. M. J. Dicer controls CD8 T-cell activation, migration, and survival. Proc. Natl. Acad. Sci. USA. 107, 21629-21634 (2010).
29. Li, Z. et al. Alternate cyclin D1 mRNA splicing modulates p27KIP1 binding and cell migration. J. Biol. Chem. 283, 7007-7015 (2008).
30. Li, Z. et al. Cyclin D1 regulates cellular migration through the inhibition of thrombospondin 1 and ROCK signaling. Mol. Cell. Biol. 26, 4240-4256 (2006). (Pubitemid 43788023)
31. Wu, K. et al. EYA1 phosphatase function is essential to drive breast cancer cell proliferation through cyclin D1. Cancer Res. 73, 4488-4499 (2013).
32. Mockenhaupt, S., Schurmann, N. & Grimm, D. When cellular networks run out of control: global dysregulation of the RNAi machinery in human pathology and therapy. Prog. Mol. Biol. Transl. Sci. 102, 165-242 (2011).
33. Conkrite, K. et al. miR-17B92 cooperates with RB pathway mutations to promote retinoblastoma. Genes Dev. 25, 1734-1745 (2011).
34. Hayes, G. D., Riedel, C. G. & Ruvkun, G. The Caenorhabditis elegans SOMI-1 zinc finger protein and SWI/SNF promote regulation of development by the mir-84 microRNA. Genes Dev. 25, 2079-2092 (2011).
35. Albanese, C. et al. Activation of the cyclin D1 gene by the E1A-associated protein p300 through AP-1 inhibits cellular apoptosis. J. Biol. Chem. 274, 34186-34195 (1999). (Pubitemid 129511756)
36. Provost, P. et al. Ribonuclease activity and RNA binding of recombinant human Dicer. EMBO J. 21, 5864-5874 (2002). (Pubitemid 35315284)
37. Wang, C. et al. Cyclin D1 repression of peroxisome proliferator-activated receptor gamma expression and transactivation. Mol. Cell Biol. 23, 6159-6173 (2003). (Pubitemid 37013094)