-
1
-
-
0036219647
-
Translating basic cancer research into new cancer therapeutics
-
Workman P, Kaye SB. Translating basic cancer research into new cancer therapeutics. Trends Mol Med 2002;8:S1-9.
-
(2002)
Trends Mol Med
, vol.8
-
-
Workman, P.1
Kaye, S.B.2
-
2
-
-
0037173334
-
Screening for drug discovery: The leading question
-
Smith A. Screening for drug discovery: the leading question. Nature 2002;418:453-9.
-
(2002)
Nature
, vol.418
, pp. 453-459
-
-
Smith, A.1
-
4
-
-
0035942736
-
Duplexes of 21-nucleotideRNAs mediate interference in cultured mammalian cells
-
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotideRNAs mediate interference in cultured mammalian cells. Nature 2001;411:494-8.
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
5
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998;391:806-11.
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
6
-
-
0346728473
-
Systematic genome-wide screens of gene function
-
Carpenter AE, Sabatini DM. Systematic genome-wide screens of gene function. Nat Rev Genet 2004;5:11-22.
-
(2004)
Nat Rev Genet
, vol.5
, pp. 11-22
-
-
Carpenter, A.E.1
Sabatini, D.M.2
-
7
-
-
0347089019
-
An approach to genomewide screens of expressed small interfering RNAs in mammalian cells
-
Zheng L, Liu J, Batalov S, et al. An approach to genomewide screens of expressed small interfering RNAs in mammalian cells. Proc Natl Acad Sci U S A 2004;101:135-40.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 135-140
-
-
Zheng, L.1
Liu, J.2
Batalov, S.3
-
8
-
-
25144446428
-
Mechanism of RNA interference, in vivo and potential clinical applications
-
Karagiannis TC, El-Osta A. Mechanism of RNA interference, in vivo and potential clinical applications. Cancer Biol Ther 2004;3:1069-74.
-
(2004)
Cancer Biol Ther
, vol.3
, pp. 1069-1074
-
-
Karagiannis, T.C.1
El-Osta, A.2
-
10
-
-
33745625836
-
Therapeutic potential of RNA interference against cancer
-
Takeshita F, Ochiya T. Therapeutic potential of RNA interference against cancer. Cancer Sci 2006;97:689-96.
-
(2006)
Cancer Sci
, vol.97
, pp. 689-696
-
-
Takeshita, F.1
Ochiya, T.2
-
11
-
-
2442668068
-
A small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics
-
Takei Y, Kadomatsu K, Yuzawa Y, Matsuo S, Muramatsu T. A small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics. Cancer Res 2004;64:3365-70.
-
(2004)
Cancer Res
, vol.64
, pp. 3365-3370
-
-
Takei, Y.1
Kadomatsu, K.2
Yuzawa, Y.3
Matsuo, S.4
Muramatsu, T.5
-
12
-
-
0033000907
-
New delivery system for plasmid DNA in vivo using atelocollagen as a carrier material: The Minipellet
-
Ochiya T, Takahama Y, Nagahara S, et al. New delivery system for plasmid DNA in vivo using atelocollagen as a carrier material: the Minipellet. Nat Med 1999;5:707-10.
-
(1999)
Nat Med
, vol.5
, pp. 707-710
-
-
Ochiya, T.1
Takahama, Y.2
Nagahara, S.3
-
13
-
-
0035930934
-
Atelocollagen-based gene transfer in cells allows high-throughput screening of gene functions
-
Honma K, Ochiya T, Nagahara S, et al. Atelocollagen-based gene transfer in cells allows high-throughput screening of gene functions. Biochem Biophys Res Commun 2001;289:1075-81.
-
(2001)
Biochem Biophys Res Commun
, vol.289
, pp. 1075-1081
-
-
Honma, K.1
Ochiya, T.2
Nagahara, S.3
-
14
-
-
3242733298
-
Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo
-
Minakuchi Y, Takeshita F, Kosaka N, et al. Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo. Nucleic Acids Res 2004;32:e109.
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Minakuchi, Y.1
Takeshita, F.2
Kosaka, N.3
-
15
-
-
0035702872
-
Skin-targeted gene transfer using in vivo electroporation
-
Maruyama H, Ataka K, Higuchi N, Sakamoto F, Gejyo F, Miyazaki J. Skin-targeted gene transfer using in vivo electroporation. Gene Ther 2001;8:1808-12.
-
(2001)
Gene Ther
, vol.8
, pp. 1808-1812
-
-
Maruyama, H.1
Ataka, K.2
Higuchi, N.3
Sakamoto, F.4
Gejyo, F.5
Miyazaki, J.6
-
16
-
-
0013798651
-
-
Coster HG. A quantitative analysis of the voltage-current relationships of fixed charge membranes and the associated property of punch- through. Biophys J 1965;5:669 -86.
-
Coster HG. A quantitative analysis of the voltage-current relationships of fixed charge membranes and the associated property of "punch- through". Biophys J 1965;5:669 -86.
-
-
-
-
18
-
-
1642487117
-
Inhibition of synapse assembly in mammalian muscle in vivo by RNA interference
-
Kong XC, Barzaghi P, Ruegg MA. Inhibition of synapse assembly in mammalian muscle in vivo by RNA interference. EMBO Rep 2004;5:183-8.
-
(2004)
EMBO Rep
, vol.5
, pp. 183-188
-
-
Kong, X.C.1
Barzaghi, P.2
Ruegg, M.A.3
-
19
-
-
0347089037
-
Electroporation and RNA interference in the rodent retina in vivo and in vitro
-
Matsuda T, Cepko CL. Electroporation and RNA interference in the rodent retina in vivo and in vitro. Proc Natl Acad Sci U S A 2004;101:16-22.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 16-22
-
-
Matsuda, T.1
Cepko, C.L.2
-
20
-
-
21744449616
-
-
Takahashi Y, Nishikawa M, Kobayashi N, Takakura Y. Gene silencing in primary and metastatic tumors by small interfering RNA delivery in mice: quantitative analysis using melanoma cells expressing firefly and sea pansy luciferases. JControl Release 2005;105:332-43
-
Takahashi Y, Nishikawa M, Kobayashi N, Takakura Y. Gene silencing in primary and metastatic tumors by small interfering RNA delivery in mice: quantitative analysis using melanoma cells expressing firefly and sea pansy luciferases. JControl Release 2005;105:332-43.
-
-
-
-
21
-
-
13544265637
-
Inhibition of gene expression in mice muscle by in vivo electrically mediated siRNA delivery
-
Golzio M, Mazzolini L, Moller P, Rols MP, Teissie J. Inhibition of gene expression in mice muscle by in vivo electrically mediated siRNA delivery. Gene Ther 2005;12:246-51.
-
(2005)
Gene Ther
, vol.12
, pp. 246-251
-
-
Golzio, M.1
Mazzolini, L.2
Moller, P.3
Rols, M.P.4
Teissie, J.5
-
22
-
-
33747177852
-
Combinational antitumor effect of siRNA against midkine and paclitaxel on growth of human prostate cancer xenografts
-
Takei Y, Kadomatsu K, Goto T, Muramatsu T. Combinational antitumor effect of siRNA against midkine and paclitaxel on growth of human prostate cancer xenografts. Cancer 2006;107:864-73.
-
(2006)
Cancer
, vol.107
, pp. 864-873
-
-
Takei, Y.1
Kadomatsu, K.2
Goto, T.3
Muramatsu, T.4
-
23
-
-
0030050025
-
Flt-1 but not KDR/Flk-1 tyrosine kinase is a receptor for placenta growth factor, which is related to vascular endothelial growth factor
-
Sawano A, Takahashi T, Yamaguchi S, Aonuma M, Shibuya M. Flt-1 but not KDR/Flk-1 tyrosine kinase is a receptor for placenta growth factor, which is related to vascular endothelial growth factor. Cell Growth Differ 1996;7:213-21.
-
(1996)
Cell Growth Differ
, vol.7
, pp. 213-221
-
-
Sawano, A.1
Takahashi, T.2
Yamaguchi, S.3
Aonuma, M.4
Shibuya, M.5
-
24
-
-
33746253891
-
Interaction between stromal fibroblasts and colorectal cancer cells in the expression of vascular endothelial growth factor
-
Koshida Y, Kuranami M, Watanabe M. Interaction between stromal fibroblasts and colorectal cancer cells in the expression of vascular endothelial growth factor. J Surg Res 2006;134:270-7.
-
(2006)
J Surg Res
, vol.134
, pp. 270-277
-
-
Koshida, Y.1
Kuranami, M.2
Watanabe, M.3
-
25
-
-
0035577793
-
Antisense oligodeoxynucleotide targeted to Midkine, a heparin-binding growth factor, suppresses tumorigenicity of mouse rectal carcinoma cells
-
Takei Y, Kadomatsu K, Matsuo S, et al. Antisense oligodeoxynucleotide targeted to Midkine, a heparin-binding growth factor, suppresses tumorigenicity of mouse rectal carcinoma cells. Cancer Res 2001;61:8486-91.
-
(2001)
Cancer Res
, vol.61
, pp. 8486-8491
-
-
Takei, Y.1
Kadomatsu, K.2
Matsuo, S.3
-
26
-
-
0037188742
-
5′-,3′-inverted thymidine-modified antisense oligodeoxynucleotide targeting midkine. Its design and application for cancer therapy
-
Takei Y, Kadomatsu K, Itoh H, et al. 5′-,3′-inverted thymidine-modified antisense oligodeoxynucleotide targeting midkine. Its design and application for cancer therapy. JBiol Chem 2002;277:23800-6.
-
(2002)
JBiol Chem
, vol.277
, pp. 23800-23806
-
-
Takei, Y.1
Kadomatsu, K.2
Itoh, H.3
-
27
-
-
14044263533
-
Morpholino antisense oligomer targeting human midkine: Its application for cancer therapy
-
Takei Y, Kadomatsu K, Yuasa K, Sato W, Muramatsu T. Morpholino antisense oligomer targeting human midkine: its application for cancer therapy. Int JCancer 2005;114:490-7.
-
(2005)
Int JCancer
, vol.114
, pp. 490-497
-
-
Takei, Y.1
Kadomatsu, K.2
Yuasa, K.3
Sato, W.4
Muramatsu, T.5
-
28
-
-
84865416014
-
Electrical impedance spectroscopy for rapid and noninvasive analysis of skin electroporation
-
Jaroszeski MJ, Heller R, Gilbert R, editors, Totowa NJ, Human Press, Inc
-
Pliquett U, Prausnitz MR. Electrical impedance spectroscopy for rapid and noninvasive analysis of skin electroporation. In: Jaroszeski MJ, Heller R, Gilbert R, editors. Methods in molecular medicine electrochemotherapy, electrogenetherapy, and transdermal drug delivery. Electrically mediated delivery of molecules to cells. Totowa (NJ): Human Press, Inc.; 2000. p. 377-406.
-
(2000)
Methods in molecular medicine electrochemotherapy, electrogenetherapy, and transdermal drug delivery. Electrically mediated delivery of molecules to cells
, pp. 377-406
-
-
Pliquett, U.1
Prausnitz, M.R.2
-
29
-
-
0022623044
-
Use of electroporation to introduce biologically active foreign genes into primary rat hepatocytes
-
Tur-Kaspa R, Teicher L, Levine BJ, Skoultchi AI, Shafritz DA. Use of electroporation to introduce biologically active foreign genes into primary rat hepatocytes. Mol Cell Biol 1986;6:716-8.
-
(1986)
Mol Cell Biol
, vol.6
, pp. 716-718
-
-
Tur-Kaspa, R.1
Teicher, L.2
Levine, B.J.3
Skoultchi, A.I.4
Shafritz, D.A.5
-
30
-
-
0023925948
-
DNA transfection of Escherichia coli by electroporation
-
Taketo A. DNA transfection of Escherichia coli by electroporation. Biochim Biophys Acta 1988;949:318-24.
-
(1988)
Biochim Biophys Acta
, vol.949
, pp. 318-324
-
-
Taketo, A.1
-
32
-
-
0030575192
-
In vivo gene electroinjection and expression in rat liver
-
Heller R, Jaroszeski M, Atkin A, et al. In vivo gene electroinjection and expression in rat liver. FEBS Lett 1996;389:225-8.
-
(1996)
FEBS Lett
, vol.389
, pp. 225-228
-
-
Heller, R.1
Jaroszeski, M.2
Atkin, A.3
-
33
-
-
9044230116
-
High-efficiency in vivo gene transfer using intraarterial plasmid DNA injection following in vivo electroporation
-
Nishi T, Yoshizato K, Yamashiro S, et al. High-efficiency in vivo gene transfer using intraarterial plasmid DNA injection following in vivo electroporation. Cancer Res 1996;56:1050-5.
-
(1996)
Cancer Res
, vol.56
, pp. 1050-1055
-
-
Nishi, T.1
Yoshizato, K.2
Yamashiro, S.3
-
34
-
-
0031753867
-
Gene transfer into muscle by electroporation in vivo
-
Aihara H, Miyazaki J. Gene transfer into muscle by electroporation in vivo. Nat Biotechnol 1998;16:867-70.
-
(1998)
Nat Biotechnol
, vol.16
, pp. 867-870
-
-
Aihara, H.1
Miyazaki, J.2
-
35
-
-
33646201069
-
Electroporation- enhanced nonviral gene transfer for the prevention or treatment of immunological, endocrine and neoplastic diseases
-
Prud'homme GJ, Glinka Y, Khan AS, Draghia-Akli R. Electroporation- enhanced nonviral gene transfer for the prevention or treatment of immunological, endocrine and neoplastic diseases. Curr Gene Ther 2006;6:243-73.
-
(2006)
Curr Gene Ther
, vol.6
, pp. 243-273
-
-
Prud'homme, G.J.1
Glinka, Y.2
Khan, A.S.3
Draghia-Akli, R.4
-
36
-
-
9144260053
-
IL-12 gene therapy is an effective therapeutic strategy for hepatocellular carcinoma in immunosuppressed mice
-
Harada N, Shimada M, Okano S, et al. IL-12 gene therapy is an effective therapeutic strategy for hepatocellular carcinoma in immunosuppressed mice. JImmunol 2004;173:6635-44.
-
(2004)
JImmunol
, vol.173
, pp. 6635-6644
-
-
Harada, N.1
Shimada, M.2
Okano, S.3
-
37
-
-
0035110705
-
Electroporation-mediated interleukin-12 gene therapy for hepatocellular carcinoma in the mice model
-
Yamashita YI, Shimada M, Hasegawa H, et al. Electroporation-mediated interleukin-12 gene therapy for hepatocellular carcinoma in the mice model. Cancer Res 2001;61:1005-12.
-
(2001)
Cancer Res
, vol.61
, pp. 1005-1012
-
-
Yamashita, Y.I.1
Shimada, M.2
Hasegawa, H.3
-
38
-
-
0003214464
-
Instrumentation and electrodes for in vivo electroporation
-
Jaroszeski MJ, Heller R, Gilbert R, editors, Totowa NJ, Human Press, Inc
-
Hofmann GA. Instrumentation and electrodes for in vivo electroporation. In: Jaroszeski MJ, Heller R, Gilbert R, editors. Methods in molecular medicine electrochemotherapy, electrogenetherapy, and transdermal drug delivery. Electrically mediated delivery of molecules to cells. Totowa (NJ): Human Press, Inc.; 2000. p. 37-61.
-
(2000)
Methods in molecular medicine electrochemotherapy, electrogenetherapy, and transdermal drug delivery. Electrically mediated delivery of molecules to cells
, pp. 37-61
-
-
Hofmann, G.A.1
-
39
-
-
13344275233
-
Phase I/II trial for the treatment of cutaneous and subcutaneous tumors using electrochemotherapy
-
Heller R, Jaroszeski MJ, Glass LF, et al. Phase I/II trial for the treatment of cutaneous and subcutaneous tumors using electrochemotherapy. Cancer 1996;77:964-71.
-
(1996)
Cancer
, vol.77
, pp. 964-971
-
-
Heller, R.1
Jaroszeski, M.J.2
Glass, L.F.3
-
40
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971;285:1182-6.
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
41
-
-
0028929803
-
Angiogenesis in cancer, vascular, rheumatoid and other disease
-
Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1995;1:27-31.
-
(1995)
Nat Med
, vol.1
, pp. 27-31
-
-
Folkman, J.1
-
42
-
-
0031969264
-
Angiogenesis and tumor metastasis
-
Zetter BR. Angiogenesis and tumor metastasis. Annu Rev Med 1998;49:407-24.
-
(1998)
Annu Rev Med
, vol.49
, pp. 407-424
-
-
Zetter, B.R.1
-
43
-
-
0024818355
-
Vascular endothelial growth factor is a secreted angiogenic mitogen
-
Leung DW, Cachianes G, Kuang WJ, Goeddel DV, Ferrara N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 1989;246:1306-9.
-
(1989)
Science
, vol.246
, pp. 1306-1309
-
-
Leung, D.W.1
Cachianes, G.2
Kuang, W.J.3
Goeddel, D.V.4
Ferrara, N.5
-
44
-
-
0027197245
-
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumor growth in vivo
-
Kim J, Li B, Winer J, et al. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumor growth in vivo. Nature 1993;362:841-4.
-
(1993)
Nature
, vol.362
, pp. 841-844
-
-
Kim, J.1
Li, B.2
Winer, J.3
-
45
-
-
0034665166
-
Selective inhibition of vascular endothelial growth factor (VEGF-A) receptor 2 (KDR/Flk-1) activity by a monoclonal antibody blocks tumor growth in mice
-
Brekken RF, Overholser JP, Stastny VA, Waltenberger J, Minna JD, Thorpe PE. Selective inhibition of vascular endothelial growth factor (VEGF-A) receptor 2 (KDR/Flk-1) activity by a monoclonal antibody blocks tumor growth in mice. Cancer Res 2000;60:5117-24.
-
(2000)
Cancer Res
, vol.60
, pp. 5117-5124
-
-
Brekken, R.F.1
Overholser, J.P.2
Stastny, V.A.3
Waltenberger, J.4
Minna, J.D.5
Thorpe, P.E.6
-
46
-
-
0037143764
-
VEGF-A-Trap: A VEGF-A blocker with potent antitumor effects
-
Holash J, Davis S, Papadopoulos N, et al. VEGF-A-Trap: a VEGF-A blocker with potent antitumor effects. Proc Natl Acad Sci U S A 2002;99:11393-8.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 11393-11398
-
-
Holash, J.1
Davis, S.2
Papadopoulos, N.3
-
47
-
-
0035431418
-
Clinical trials referral resource: Current clinical trials of the anti-VEGF monoclonal antibody bevacizumab
-
Chen HX, Gore-Langton RE, Cheson BD. Clinical trials referral resource: current clinical trials of the anti-VEGF monoclonal antibody bevacizumab. Oncology 2001;15:1017.
-
(2001)
Oncology
, vol.15
, pp. 1017
-
-
Chen, H.X.1
Gore-Langton, R.E.2
Cheson, B.D.3
|