Bromelain and N-acetylcysteine inhibit proliferation and survival of gastrointestinal cancer cells in vitro: Significance of combination therapy

Journal of Experimental and Clinical Cancer Research

Volumn 33, Issue 1, 2014, Pages

  Amini, Afshin ^a   Masoumi Moghaddam, Samar ^a   Ehteda, Anahid ^a   Morris, David Lawson ^a  

^a ST GEORGE HOSPITAL   (Australia)

Author keywords

Bromelain; Gastrointestinal carcinoma; N acetylcysteine; Proliferation; Survival

Indexed keywords

ACETYLCYSTEINE; AUTOPHAGY PROTEIN 12; AUTOPHAGY PROTEIN 3; AUTOPHAGY PROTEIN 5; AUTOPHAGY PROTEIN 7; BECLIN 1; BROMELAIN; CASPASE 3; CASPASE 7; CASPASE 8; CELL MARKER; CYCLIN A; CYCLIN B; CYCLIN D; CYTOCHROME C; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROCASPASE 9; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN LC3 II; SULFORHODAMINE B; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT;

APOPTOSIS; ARTICLE; ASSAY; AUTOPHAGOSOME; CANCER CELL DESTRUCTION; CARCINOMA CELL LINE; CELL CYCLE REGULATION; CELL PROLIFERATION; CELL SURVIVAL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOWN REGULATION; DRUG POTENTIATION; ENZYME PHOSPHORYLATION; GASTROINTESTINAL CARCINOMA CELL LINE; GROWTH INHIBITION; HT29 5F12 CELL LINE; HT29 5M21 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; KATO III CELL LINE; LS174T CELL LINE; MKN45 CELL LINE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN SUBUNIT; SULFORHODAMINE B ASSAY; TUNEL ASSAY; WESTERN BLOTTING; DRUG EFFECTS; GASTROINTESTINAL NEOPLASMS; HT 29 CELL LINE; PATHOLOGY; TUMOR CELL LINE;

ACETYLCYSTEINE; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BROMELAINS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DRUG SYNERGISM; GASTROINTESTINAL NEOPLASMS; HT29 CELLS; HUMANS;

EID: 84922143334     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/s13046-014-0092-7     Document Type: Article

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