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Volumn 42, Issue 1, 2013, Pages 211-218

N-acetylcysteine potentiates doxorubicin-induced ATM and p53 activation in ovarian cancer cells

Author keywords

ATM; Doxorubicin; N acetylcysteine; Ovarian cancer; P53

Indexed keywords

ACETYLCYSTEINE; ACTIN; ATM PROTEIN; DOXORUBICIN; EPIDERMAL GROWTH FACTOR; HISTONE H2AX; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN P53; PROTEIN S6; PYRROLIDINE DITHIOCARBAMATE; SERINE; TUBULIN; VIMENTIN;

EID: 84873694439     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2012.1680     Document Type: Article
Times cited : (21)

References (42)
  • 1
    • 67349167673 scopus 로고    scopus 로고
    • Morphological alterations induced by doxorubicin on H9c2 myoblasts: Nuclear, mitochondrial, and cytoskeletal targets
    • Sardao VA, Oliveira PJ, Holy J, Oliveira CR and Wallace KB: Morphological alterations induced by doxorubicin on H9c2 myoblasts: nuclear, mitochondrial, and cytoskeletal targets. Cell Biol Toxicol 25: 227-243, 2009.
    • (2009) Cell Biol Toxicol , vol.25 , pp. 227-243
    • Sardao, V.A.1    Oliveira, P.J.2    Holy, J.3    Oliveira, C.R.4    Wallace, K.B.5
  • 2
    • 77956912169 scopus 로고    scopus 로고
    • Switching p53-dependent growth arrest to apoptosis via the inhibition of DNA damage-activated kinases
    • Hublarova P, Greplova K, Holcakova J, Vojtesek B and Hrstka R: Switching p53-dependent growth arrest to apoptosis via the inhibition of DNA damage-activated kinases. Cell Mol Biol Lett 15: 473-484, 2010.
    • (2010) Cell Mol Biol Lett , vol.15 , pp. 473-484
    • Hublarova, P.1    Greplova, K.2    Holcakova, J.3    Vojtesek, B.4    Hrstka, R.5
  • 3
    • 23044467656 scopus 로고    scopus 로고
    • Two distinct modes of cell death induced by doxorubicin: Apoptosis and cell death through mitotic catastrophe accompanied by senescence-like phenotype
    • DOI 10.1038/sj.onc.1208627
    • Eom YW, Kim MA, Park SS, Goo MJ, Kwon HJ, Sohn S, Kim WH, Yoon G and Choi KS: Two distinct modes of cell death induced by doxorubicin: apoptosis and cell death through mitotic catastrophe accompanied by senescence-like phenotype. Oncogene 24: 4765-4777, 2005. (Pubitemid 41076294)
    • (2005) Oncogene , vol.24 , Issue.30 , pp. 4765-4777
    • Eom, Y.-W.1    Kim, M.A.2    Park, S.S.3    Goo, M.J.4    Kwon, H.J.5    Sohn, S.6    Kim, W.-H.7    Yoon, G.8    Choi, K.S.9
  • 4
    • 11144234525 scopus 로고    scopus 로고
    • Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species
    • DOI 10.1074/jbc.M406879200
    • Kurz EU, Douglas P and Lees-Miller SP: Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species. J Biol Chem 279: 53272-53281, 2004. (Pubitemid 40051831)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.51 , pp. 53272-53281
    • Kurz, E.U.1    Douglas, P.2    Lees-Miller, S.P.3
  • 5
    • 0029049292 scopus 로고
    • A prescreening system for potential antiproliferative agents: Implications for local treatment strategies of postangioplasty restenosis
    • Voisard R, Seitzer U, Baur R, Dartsch PC, Osterhues H, Hoher M and Hombach V: A prescreening system for potential antiproliferative agents: implications for local treatment strategies of postangioplasty restenosis. Int J Cardiol 51: 15-28, 1995.
    • (1995) Int J Cardiol , vol.51 , pp. 15-28
    • Voisard, R.1    Seitzer, U.2    Baur, R.3    Dartsch, P.C.4    Osterhues, H.5    Hoher, M.6    Hombach, V.7
  • 6
    • 3042835140 scopus 로고    scopus 로고
    • Roles of cyclin-dependent kinase 4 and p53 in neuronal cell death induced by doxorubicin on cerebellar granule neurons in mouse
    • DOI 10.1016/j.neulet.2004.04.083, PII S0304394004005488
    • Otsuka Y, Tanaka T, Uchida D, Noguchi Y, Saeki N, Saito Y and Tatsuno I: Roles of cyclin-dependent kinase 4 and p53 in neuronal cell death induced by doxorubicin on cerebellar granule neurons in mouse. Neurosci Lett 365: 180-185, 2004. (Pubitemid 38891778)
    • (2004) Neuroscience Letters , vol.365 , Issue.3 , pp. 180-185
    • Otsuka, Y.1    Tanaka, T.2    Uchida, D.3    Noguchi, Y.4    Saeki, N.5    Saito, Y.6    Tatsuno, I.7
  • 7
    • 1342304040 scopus 로고    scopus 로고
    • rsk Signaling Pathway in Response to Distinct Forms of DNA Damage
    • DOI 10.1128/MCB.24.5.1823-1835.2004
    • Panta GR, Kaur S, Cavin LG, Cortes ML, Mercurio F, Lothstein L, Sweatman TW, Israel M and Arsura M: ATM and the catalytic subunit of DNA-dependent protein kinase activate NF-kappaB through a common MEK/extracellular signal-regulated kinase/p90(rsk) signaling pathway in response to distinct forms of DNA damage. Mol Cell Biol 24: 1823-1835, 2004. (Pubitemid 38248925)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.5 , pp. 1823-1835
    • Panta, G.R.1    Kaur, S.2    Cavin, L.G.3    Cortes, M.L.4    Mercurio, F.5    Lothstein, L.6    Sweatman, T.W.7    Israel, M.8    Arsura, M.9
  • 8
    • 82555205486 scopus 로고    scopus 로고
    • Preclinical testing of PI3K/AKT/mTOR signaling inhibitors in a mouse model of ovarian endometrioid adenocarcinoma
    • Wu R, Hu TC, Rehemtulla A, Fearon ER and Cho KR: Preclinical testing of PI3K/AKT/mTOR signaling inhibitors in a mouse model of ovarian endometrioid adenocarcinoma. Clin Cancer Res 17: 7359-7372, 2011.
    • (2011) Clin Cancer Res , vol.17 , pp. 7359-7372
    • Wu, R.1    Hu, T.C.2    Rehemtulla, A.3    Fearon, E.R.4    Cho, K.R.5
  • 9
    • 77950482759 scopus 로고    scopus 로고
    • Features of senescence and cell death induced by doxorubicin in A549 cells: Organization and level of selected cytoskeletal proteins
    • Litwiniec A, Grzanka A, Helmin-Basa A, Gackowska L and Grzanka D: Features of senescence and cell death induced by doxorubicin in A549 cells: organization and level of selected cytoskeletal proteins. J Cancer Res Clin Oncol 136: 717-736, 2010.
    • (2010) J Cancer Res Clin Oncol , vol.136 , pp. 717-736
    • Litwiniec, A.1    Grzanka, A.2    Helmin-Basa, A.3    Gackowska, L.4    Grzanka, D.5
  • 10
    • 0642345196 scopus 로고    scopus 로고
    • Cytoskeletal reorganization during process of apoptosis induced by cytostatic drugs in K-562 and HL-60 leukemia cell lines
    • DOI 10.1016/S0006-2952(03)00532-X, PII S000629520300532X
    • Grzanka A, Grzanka D and Orlikowska M: Cytoskeletal reorganization during process of apoptosis induced by cytostatic drugs in K-562 and HL-60 leukemia cell lines. Biochem Pharmacol 66: 1611-1617, 2003. (Pubitemid 38373353)
    • (2003) Biochemical Pharmacology , vol.66 , Issue.8 , pp. 1611-1617
    • Grzanka, A.1    Grzanka, D.2    Orlikowska, M.3
  • 11
    • 50549093975 scopus 로고    scopus 로고
    • Interference with actin dynamics is superior to disturbance of microtubule function in the inhibition of human ovarian cancer cell motility
    • Bijman MN, van Berkel MP, van Nieuw Amerongen GP and Boven E: Interference with actin dynamics is superior to disturbance of microtubule function in the inhibition of human ovarian cancer cell motility. Biochem Pharmacol 76: 707-716, 2008.
    • (2008) Biochem Pharmacol , vol.76 , pp. 707-716
    • Bijman, M.N.1    Van Berkel, M.P.2    Van Nieuw Amerongen, G.P.3    Boven, E.4
  • 12
    • 34547619923 scopus 로고    scopus 로고
    • Paclitaxel and ceramide synergistically induce cell death with transient activation of EGFR and ERK pathway in pancreatic cancer cells
    • Qiu L, Zhou C, Sun Y, Di W, Scheffler E, Healey S, Wanebo H, Kouttab N, Chu W and Wan Y: Paclitaxel and ceramide synergistically induce cell death with transient activation of EGFR and ERK pathway in pancreatic cancer cells. Oncol Rep 16: 907-913, 2006.
    • (2006) Oncol Rep , vol.16 , pp. 907-913
    • Qiu, L.1    Zhou, C.2    Sun, Y.3    Di Scheffler, W.E.4    Healey, S.5    Wanebo, H.6    Kouttab, N.7    Chu, W.8    Wan, Y.9
  • 13
    • 0017687926 scopus 로고
    • The phagokinetic tracks of 3T3 cells
    • Albrecht-Buehler G: The phagokinetic tracks of 3T3 cells. Cell 11: 395-404, 1977.
    • (1977) Cell , vol.11 , pp. 395-404
    • Albrecht-Buehler, G.1
  • 14
    • 24344483143 scopus 로고    scopus 로고
    • Transient activation of EGFR/AKT cell survival pathway and expression of survivin contribute to reduced sensitivity of human melanoma cells to betulinic acid
    • Qiu L, Wang Q, Di W, Jiang Q, Schefeller E, Derby S, Wanebo H, Yan B and Wan Y: Transient activation of EGFR/AKT cell survival pathway and expression of survivin contribute to reduced sensitivity of human melanoma cells to betulinic acid. Int J Oncol 27: 823-830, 2005.
    • (2005) Int J Oncol , vol.27 , pp. 823-830
    • Qiu, L.1    Wang, Q.2    Di Jiang, W.Q.3    Schefeller, E.4    Derby, S.5    Wanebo, H.6    Yan, B.7    Wan, Y.8
  • 15
    • 33644643243 scopus 로고    scopus 로고
    • Targeted inhibition of transient activation of the EGFR-mediated cell survival pathway enhances paclitaxel-induced ovarian cancer cell death
    • Qiu L, Di W, Jiang Q, Scheffler E, Derby S, Yang J, Kouttab N, Wanebo H, Yan B and Wan Y: Targeted inhibition of transient activation of the EGFR-mediated cell survival pathway enhances paclitaxel-induced ovarian cancer cell death. Int J Oncol 27: 1441-1448, 2005.
    • (2005) Int J Oncol , vol.27 , pp. 1441-1448
    • Qiu, L.1    Di Jiang, W.Q.2    Scheffler, E.3    Derby, S.4    Yang, J.5    Kouttab, N.6    Wanebo, H.7    Yan, B.8    Wan, Y.9
  • 16
    • 34249331320 scopus 로고    scopus 로고
    • Stobadine inhibits doxorubicin-induced apoptosis through a caspase-9 dependent pathway in P815 mastocytoma cells
    • DOI 10.1016/j.cellbi.2007.03.008, PII S1065699507000789
    • Bagriacik EU, Uslu K, Yurtcu E, Stefek M and Karasu C: Stobadine inhibits doxorubicin-induced apoptosis through a caspase-9 dependent pathway in P815 mastocytoma cells. Cell Biol Int 31: 979-984, 2007. (Pubitemid 46819068)
    • (2007) Cell Biology International , vol.31 , Issue.9 , pp. 979-984
    • Umit Bagriacik, E.1    Uslu, K.2    Yurtcu, E.3    Stefek, M.4    Karasu, C.5
  • 17
    • 80455164368 scopus 로고    scopus 로고
    • The role of reactive oxygen species in WP 631-induced death of human ovarian cancer cells: A comparison with the effect of doxorubicin
    • Rogalska A, Gajek A, Szwed M, Jozwiak Z and Marczak A: The role of reactive oxygen species in WP 631-induced death of human ovarian cancer cells: a comparison with the effect of doxorubicin. Toxicol In Vitro 25: 1712-1720, 2011.
    • (2011) Toxicol in Vitro , vol.25 , pp. 1712-1720
    • Rogalska, A.1    Gajek, A.2    Szwed, M.3    Jozwiak, Z.4    Marczak, A.5
  • 18
    • 0031686030 scopus 로고    scopus 로고
    • Doxorubicin chemomyectomy as a treatment for cervical dystonia: Histological assessment after direct injection into the sternocleidomastoid muscle
    • DOI 10.1002/(SICI)1097-4598(199811)21:11<1457::AID-MUS14>3.0.CO;2-Y
    • McLoon LK, Falkenberg JH, Dykstra D and Iaizzo PA: Doxorubicin chemomyectomy as a treatment for cervical dystonia: histological assessment after direct injection into the sternocleidomastoid muscle. Muscle Nerve 21: 1457-1464, 1998. (Pubitemid 28453134)
    • (1998) Muscle and Nerve , vol.21 , Issue.11 , pp. 1457-1464
    • McLoon, L.K.1    Falkenberg, J.H.2    Dykstra, D.3    Iaizzo, P.A.4
  • 21
    • 0027656134 scopus 로고
    • DXR depresses the alpha-actinin-induced formation of actin bundles
    • Dalledonne I, Milzani A and Colombo R: DXR depresses the alpha-actinin-induced formation of actin bundles. Cancer Biochem Biophys 13: 245-254, 1993. (Pubitemid 2013355)
    • (1993) Cancer Biochemistry Biophysics , vol.13 , Issue.4 , pp. 245-254
    • Dalledonne, I.1    Milzani, A.2    Colombo, R.3
  • 22
    • 0027355378 scopus 로고
    • The effects of doxorubicin on embryonic spinal motoneurons cultured in vitro: Cytoskeletal response
    • Necco A, Usardi C, Scari G, Islam K, Melzner I and Vergani G: The effects of doxorubicin on embryonic spinal motoneurons cultured in vitro: cytoskeletal response. Cytotechnology 11: 133-141, 1993.
    • (1993) Cytotechnology , vol.11 , pp. 133-141
    • Necco, A.1    Usardi, C.2    Scari, G.3    Islam, K.4    Melzner, I.5    Vergani, G.6
  • 23
  • 24
    • 0022550092 scopus 로고
    • Cardiac actin interactions with doxorubicin in vitro
    • DOI 10.1016/0014-4800(86)90028-6
    • Mariano R, Gonzalez B and Lewis W: Cardiac actin interactions with doxorubicin in vitro. Exp Mol Pathol 44: 7-13, 1986. (Pubitemid 16038150)
    • (1986) Experimental and Molecular Pathology , vol.44 , Issue.1 , pp. 7-13
    • Mariano, R.1    Gonzalez, B.2    Lewis, W.3
  • 26
    • 34248582844 scopus 로고    scopus 로고
    • Novel action of paclitaxel against cancer cells: Bystander effect mediated by reactive oxygen species
    • DOI 10.1158/0008-5472.CAN-06-3914
    • Alexandre J, Hu Y, Lu W, Pelicano H and Huang P: Novel action of paclitaxel against cancer cells: bystander effect mediated by reactive oxygen species. Cancer Res 67: 3512-3517, 2007. (Pubitemid 46762129)
    • (2007) Cancer Research , vol.67 , Issue.8 , pp. 3512-3517
    • Alexandre, J.1    Hu, Y.2    Lu, W.3    Pelicano, H.4    Huang, P.5
  • 27
    • 77956897107 scopus 로고    scopus 로고
    • N,N-Dimethyl phytosphingosine sensitizes HL-60/MX2, a multidrug-resistant variant of HL-60 cells, to doxorubicin-induced cytotoxicity through ROS-mediated release of cytochrome c and AIF
    • Kim BM, Choi YJ, Lee YH, Joe YA and Hong SH: N, N-Dimethyl phytosphingosine sensitizes HL-60/MX2, a multidrug-resistant variant of HL-60 cells, to doxorubicin-induced cytotoxicity through ROS-mediated release of cytochrome c and AIF. Apoptosis 15: 982-993, 2010.
    • (2010) Apoptosis , vol.15 , pp. 982-993
    • Kim, B.M.1    Choi, Y.J.2    Lee, Y.H.3    Joe, Y.A.4    Hong, S.H.5
  • 29
    • 80053966362 scopus 로고    scopus 로고
    • Chromosomal breaks during mitotic catastrophe trigger gammaH2AX-ATM-p53-mediated apoptosis
    • Imreh G, Norberg HV, Imreh S and Zhivotovsky B: Chromosomal breaks during mitotic catastrophe trigger gammaH2AX-ATM-p53-mediated apoptosis. J Cell Sci 124: 2951-2963, 2011.
    • (2011) J Cell Sci , vol.124 , pp. 2951-2963
    • Imreh, G.1    Norberg, H.V.2    Imreh, S.3    Zhivotovsky, B.4
  • 30
    • 34547728723 scopus 로고    scopus 로고
    • Protective effect of N-acetylcysteine, caffeic acid and vitamin E on doxorubicin hepatotoxicity
    • DOI 10.1177/0960327107076885
    • Gokcimen A, Cim A, Tola HT, Bayram D, Kocak A, Ozguner F and Ayata A: Protective effect of N-acetylcysteine, caffeic acid and vitamin E on doxorubicin hepatotoxicity. Hum Exp Toxicol 26: 519-525, 2007. (Pubitemid 47224747)
    • (2007) Human and Experimental Toxicology , vol.26 , Issue.6 , pp. 519-525
    • Gokcimen, A.1    Cim, A.2    Tola, H.T.3    Bayram, D.4    Kocak, A.5    Ozguner, F.6    Ayata, A.7
  • 31
    • 70449109328 scopus 로고    scopus 로고
    • Anticancer DNA intercalators cause p53-dependent mitochondrial DNA nucleoid re-modelling
    • Ashley N and Poulton J: Anticancer DNA intercalators cause p53-dependent mitochondrial DNA nucleoid re-modelling. Oncogene 28: 3880-3891, 2009.
    • (2009) Oncogene , vol.28 , pp. 3880-3891
    • Ashley, N.1    Poulton, J.2
  • 32
    • 0030731233 scopus 로고    scopus 로고
    • Cytoskeleton alteration in MCF7R cells, a multidrug resistant human breast cancer cell line
    • Bichat F, Mouawad R, Solis-Recendez G, Khayat D and Bastian G: Cytoskeleton alteration in MCF7R cells, a multidrug resistant human breast cancer cell line. Anticancer Res 17: 3393-3401, 1997. (Pubitemid 27522300)
    • (1997) Anticancer Research , vol.17 , Issue.A5 , pp. 3393-3401
    • Bichat, F.1    Mouawad, R.2    Solis-Recendez, G.3    Khayat, D.4    Bastian, G.5
  • 33
    • 0034878825 scopus 로고    scopus 로고
    • Estimation of changes in vimentin filaments induced by etoposide and doxorubicin in human leukemia cell line K-562 by using immunofiuorescence microscopy
    • Grzanka A: Estimation of changes in vimentin filaments induced by etoposide and doxorubicin in human leukemia cell line K-562 by using immunofluorescence microscopy. Neoplasma 48: 285-289, 2001. (Pubitemid 32802440)
    • (2001) Neoplasma , vol.48 , Issue.4 , pp. 285-289
    • Grzanka, A.1
  • 34
    • 2942606992 scopus 로고    scopus 로고
    • Fluorescence and ultrastructural localization of actin distribution patterns in the nucleus of HL-60 and K-562 cell lines treated with cytostatic drugs
    • Grzanka A, Grzanka D and Orlikowska M: Fluorescence and ultrastructural localization of actin distribution patterns in the nucleus of HL-60 and K-562 cell lines treated with cytostatic drugs. Oncol Rep 11: 765-770, 2004.
    • (2004) Oncol Rep , vol.11 , pp. 765-770
    • Grzanka, A.1    Grzanka, D.2    Orlikowska, M.3
  • 35
    • 79952763658 scopus 로고    scopus 로고
    • Actin cytoskeleton reorganization correlates with cofilin nuclear expression and ultrastructural changes in cho aa8 cell line after apoptosis and mitotic catastrophe induction by doxorubicin
    • Grzanka D, Marszalek A, Izdebska M, Gackowska L, Andrzej Szczepanski M and Grzanka A: Actin cytoskeleton reorganization correlates with cofilin nuclear expression and ultrastructural changes in cho aa8 cell line after apoptosis and mitotic catastrophe induction by doxorubicin. Ultrastruct Pathol 35: 130-138, 2011.
    • (2011) Ultrastruct Pathol , vol.35 , pp. 130-138
    • Grzanka, D.1    Marszalek, A.2    Izdebska, M.3    Gackowska, L.4    Andrzej Szczepanski, M.5    Grzanka, A.6
  • 36
    • 79955070726 scopus 로고    scopus 로고
    • Akt, 14-3-3zeta, and vimentin mediate a drug-resistant invasive phenotype in diffuse large B-cell lymphoma
    • Maxwell SA, Cherry EM and Bayless KJ: Akt, 14-3-3zeta, and vimentin mediate a drug-resistant invasive phenotype in diffuse large B-cell lymphoma. Leuk Lymphoma 52: 849-864, 2011.
    • (2011) Leuk Lymphoma , vol.52 , pp. 849-864
    • Maxwell, S.A.1    Cherry, E.M.2    Bayless, K.J.3
  • 37
    • 7044249025 scopus 로고    scopus 로고
    • N-acetylcysteine enhances multidrug resistance-associated protein I mediated doxorubicin resistance
    • DOI 10.1111/j.1365-2362.2004.01411.x
    • Akan I, Akan S, Akca H, Savas B and Ozben T: N-acetylcysteine enhances multidrug resistance-associated protein 1 mediated doxorubicin resistance. Eur J Clin Invest 34: 683-689, 2004. (Pubitemid 39423026)
    • (2004) European Journal of Clinical Investigation , vol.34 , Issue.10 , pp. 683-689
    • Akan, I.1    Akan, S.2    Akca, H.3    Savas, B.4    Ozben, T.5
  • 38
    • 0021893818 scopus 로고
    • Comparison of the effectiveness of (±)-1,2-bis(3,5- dioxopiperazinyl-1-yl)propane (ICRF-187) and N-acetylcysteine in preventing chronic doxorubicin cardiotoxicity in beagles
    • Herman EH, Ferrans VJ, Myers CE and Van Vleet JF: Comparison of the effectiveness of (+/-)-1, 2-bis(3, 5-dioxopiperazinyl-1-yl)propane (ICRF-187) and N-acetylcysteine in preventing chronic doxorubicin cardiotoxicity in beagles. Cancer Res 45: 276-281, 1985. (Pubitemid 15196968)
    • (1985) Cancer Research , vol.45 , Issue.1 , pp. 276-281
    • Herman, E.H.1    Ferrans, V.J.2    Myers, C.E.3    Van Vleet, J.F.4
  • 39
    • 78649482193 scopus 로고    scopus 로고
    • N-acetylcysteine modulates doxorubicin-induced oxidative stress and antioxidant vitamin concentrations in liver of rats
    • Kockar MC, Naziroglu M, Celik O, Tola HT, Bayram D and Koyu A: N-acetylcysteine modulates doxorubicin-induced oxidative stress and antioxidant vitamin concentrations in liver of rats. Cell Biochem Funct 28: 673-677, 2010.
    • (2010) Cell Biochem Funct , vol.28 , pp. 673-677
    • Kockar, M.C.1    Naziroglu, M.2    Celik, O.3    Tola, H.T.4    Bayram, D.5    Koyu, A.6
  • 40
    • 1542439108 scopus 로고    scopus 로고
    • Protective effects of N-acetylcysteine and selenium against doxorubicin toxicity in rats
    • Park ES, Kim SD, Lee MH, Lee HS, Lee IS, Sung JK and Yoon YS: Protective effects of N-acetylcysteine and selenium against doxorubicin toxicity in rats. J Vet Sci 4: 129-136, 2003.
    • (2003) J Vet Sci , vol.4 , pp. 129-136
    • Park, E.S.1    Kim, S.D.2    Lee, M.H.3    Lee, H.S.4    Lee, I.S.5    Sung, J.K.6    Yoon, Y.S.7


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