The antioxidant N-Acetylcysteine increases 5-Fluorouracil activity against colorectal cancer xenografts in nude mice

Journal of Gastrointestinal Surgery

Volumn 5, Issue 1, 2001, Pages 91-97

  Bach, Simon P ^a   Williamson, Sarah E ^a   Marshman, Emma ^a   Kumar, Shant ^b   O’dwyer, Sarah T ^a   Potten, Christopher S ^a   Watson, Alastair J M ^c  

^a CHRISTIE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

5 Fluorouracil; Antioxidants; Apoptosis; Colorectal cancer; N acetylcysteine

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; FLUOROURACIL; SCAVENGER;

ADENOCARCINOMA; ANIMAL; APOPTOSIS; ARTICLE; CANCER TRANSPLANTATION; CELL CULTURE; COLORECTAL TUMOR; DISEASE MODEL; DRUG EFFECT; DRUG POTENTIATION; DRUG SCREENING; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; MOUSE; NICK END LABELING; NUDE MOUSE; TUMOR SUPPRESSOR GENE; XENOGRAFT;

ACETYLCYSTEINE; ADENOCARCINOMA; ANIMALS; ANTIOXIDANTS; APOPTOSIS; COLORECTAL NEOPLASMS; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; DRUG SYNERGISM; FLOW CYTOMETRY; FLUOROURACIL; FREE RADICAL SCAVENGERS; GENES, P53; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 0035221871     PISSN: 1091255X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1091-255X(01)80018-4     Document Type: Article

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