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Volumn 52, Issue 11, 2011, Pages 8224-8230

Regulation of experimental autoimmune uveoretinitis by anti-delta-like ligand 4 monoclonal antibody

Author keywords

[No Author keywords available]

Indexed keywords

DELTA LIKE LIGAND 4 ANTIBODY; GAMMA INTERFERON; GAMMA SECRETASE INHIBITOR; GLYCOPROTEIN P 15095; INTERLEUKIN 10; INTERLEUKIN 12P35; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERPHOTORECEPTOR RETINOID BINDING PROTEIN; MESSENGER RNA; MONOCLONAL ANTIBODY; NOTCH RECEPTOR; PERTUSSIS TOXIN; RETINOID RELATED ORPHAN RECEPTOR GAMMA; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; CYTOKINE; DLL4 PROTEIN, MOUSE; EYE PROTEIN; INTERSTITIAL RETINOL-BINDING PROTEIN; MEMBRANE PROTEIN; NOTCH1 PROTEIN, MOUSE; NOTCH1 RECEPTOR; NOTCH2 PROTEIN, MOUSE; NOTCH2 RECEPTOR; NOTCH4 PROTEIN, MOUSE; ONCOPROTEIN; PEPTIDE FRAGMENT; RETINOL BINDING PROTEIN; SECRETASE; SIGNAL PEPTIDE;

EID: 84855384313     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.11-7756     Document Type: Article
Times cited : (14)

References (38)
  • 2
    • 0025147232 scopus 로고
    • The natural history of uveitis
    • Nussenblatt RB. The natural history of uveitis. Int Ophthalmol. 1990;14:303-308.
    • (1990) Int Ophthalmol , vol.14 , pp. 303-308
    • Nussenblatt, R.B.1
  • 3
    • 0035658616 scopus 로고    scopus 로고
    • Immunopathology of the noninfectious posterior and intermediate uveitides
    • Boyd SR, Young S, Lightman S. Immunopathology of the noninfectious posterior and intermediate uveitides. Surv Ophthalmol. 2001;46:209-233.
    • (2001) Surv Ophthalmol , vol.46 , pp. 209-233
    • Boyd, S.R.1    Young, S.2    Lightman, S.3
  • 4
    • 0020691256 scopus 로고
    • Cyclosporin A: Alterations of the cellular immune response in S-antigeninduced experimental autoimmune uveitis
    • Nussenblatt RB, Salinas-Carmona M, Waksman BH, Gery I. Cyclosporin A: alterations of the cellular immune response in S-antigeninduced experimental autoimmune uveitis. Int Arch Allergy Appl Immunol. 1983;70:289-294.
    • (1983) Int Arch Allergy Appl Immunol , vol.70 , pp. 289-294
    • Nussenblatt, R.B.1    Salinas-Carmona, M.2    Waksman, B.H.3    Gery, I.4
  • 5
    • 0023912944 scopus 로고
    • A new model of autoimmune disease. Experimental autoimmune uveoretinitis induced in mice with two different retinal antigens
    • Caspi RR, Roberge FG, Chan CC, et al. A new model of autoimmune disease. Experimental autoimmune uveoretinitis induced in mice with two different retinal antigens. J Immunol. 1988;140: 1490-1495.
    • (1988) J Immunol , vol.140 , pp. 1490-1495
    • Caspi, R.R.1    Roberge, F.G.2    Chan, C.C.3
  • 6
    • 0021959241 scopus 로고
    • Adoptive transfer of experimental autoimmune uveoretinitis in rats. Immunopathogenic mechanisms and histologic features
    • Mochizuki M, Kuwabara T, McAllister C, Nussenblatt RB, Gery I. Adoptive transfer of experimental autoimmune uveoretinitis in rats. Immunopathogenic mechanisms and histologic features. Invest Ophthalmol Vis Sci. 1985;26:1-9.
    • (1985) Invest Ophthalmol Vis Sci , vol.26 , pp. 1-9
    • Mochizuki, M.1    Kuwabara, T.2    McAllister, C.3    Nussenblatt, R.B.4    Gery, I.5
  • 7
    • 0027055536 scopus 로고
    • Immunogenetic aspects of clinical and experimental uveitis
    • Caspi RR. Immunogenetic aspects of clinical and experimental uveitis. Reg Immunol. 1992;4:321-330.
    • (1992) Reg Immunol , vol.4 , pp. 321-330
    • Caspi, R.R.1
  • 8
    • 0030587090 scopus 로고    scopus 로고
    • Genetic susceptibility to experimental autoimmune uveoretinitis in the rat is associated with an elevated Th1 response
    • Caspi RR, Silver PB, Chan CC, et al. Genetic susceptibility to experimental autoimmune uveoretinitis in the rat is associated with an elevated Th1 response. J Immunol. 1996;157:2668-2675.
    • (1996) J Immunol , vol.157 , pp. 2668-2675
    • Caspi, R.R.1    Silver, P.B.2    Chan, C.C.3
  • 9
    • 34250005444 scopus 로고    scopus 로고
    • TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/ STAT1
    • Amadi-Obi A, Yu CR, Liu X, et al. TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/ STAT1. Nat Med. 2007;13:711-718.
    • (2007) Nat Med , vol.13 , pp. 711-718
    • Amadi-Obi, A.1    Yu, C.R.2    Liu, X.3
  • 10
    • 39049129395 scopus 로고    scopus 로고
    • Differential roles for IFN-gamma and IL-17 in experimental autoimmune uveoretinitis
    • Yoshimura T, Sonoda KH, Miyazaki Y, et al. Differential roles for IFN-gamma and IL-17 in experimental autoimmune uveoretinitis. Int Immunol. 2008;20:209-214.
    • (2008) Int Immunol , vol.20 , pp. 209-214
    • Yoshimura, T.1    Sonoda, K.H.2    Miyazaki, Y.3
  • 11
    • 13944278756 scopus 로고    scopus 로고
    • Anti-CD137 mAb treatment inhibits experimental autoimmune uveitis by limiting expansion and increasing apoptotic death of uveitogenic T-cells
    • Shao H, Fu Y, Liao T, et al. Anti-CD137 mAb treatment inhibits experimental autoimmune uveitis by limiting expansion and increasing apoptotic death of uveitogenic T-cells. Invest Ophthalmol Vis Sci. 2005;46:596-603.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 596-603
    • Shao, H.1    Fu, Y.2    Liao, T.3
  • 12
    • 33751210607 scopus 로고    scopus 로고
    • The role of the ICOS/B7RP-1 T-cell costimulatory pathway in murine experimental autoimmune uveoretinitis
    • Usui Y, Akiba H, Takeuchi M, et al. The role of the ICOS/B7RP-1 T-cell costimulatory pathway in murine experimental autoimmune uveoretinitis. Eur J Immunol. 2006;36:3071-3081.
    • (2006) Eur J Immunol , vol.36 , pp. 3071-3081
    • Usui, Y.1    Akiba, H.2    Takeuchi, M.3
  • 13
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: Cell fate control and signal integration in development
    • Artavanis-Tsakonas S, Rand MD, Lake RJ. Notch signaling: cell fate control and signal integration in development. Science. 1999;284: 770-776.
    • (1999) Science , vol.284 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 14
    • 0030199830 scopus 로고    scopus 로고
    • Expression patterns of Jagged, Delta1, Notch1, Notch2, and Notch3 genes identify ligand-receptor pairs that may function in neural development
    • Lindsell CE, Boulter J, diSibio G, Gossler A, Weinmaster G. Expression patterns of Jagged, Delta1, Notch1, Notch2, and Notch3 genes identify ligand-receptor pairs that may function in neural development. Mol Cell Neurosci. 1996;8:14-27.
    • (1996) Mol Cell Neurosci , vol.8 , pp. 14-27
    • Lindsell, C.E.1    Boulter, J.2    diSibio, G.3    Gossler, A.4    Weinmaster, G.5
  • 15
    • 2342496710 scopus 로고    scopus 로고
    • Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells
    • Amsen D, Blander JM, Lee GR, Tanigaki K, Honjo T, Flavell RA. Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells. Cell. 2004;117:515-526.
    • (2004) Cell , vol.117 , pp. 515-526
    • Amsen, D.1    Blander, J.M.2    Lee, G.R.3    Tanigaki, K.4    Honjo, T.5    Flavell, R.A.6
  • 16
    • 34248217573 scopus 로고    scopus 로고
    • Up-regulation of gene related to anergy in lymphocytes is associated with Notch-mediated human T-cell suppression
    • Kostianovsky AM, Maier LM, Baecher-Allan C, Anderson AC, Anderson DE. Up-regulation of gene related to anergy in lymphocytes is associated with Notch-mediated human T-cell suppression. J Immunol. 2007;178:6158-6163.
    • (2007) J Immunol , vol.178 , pp. 6158-6163
    • Kostianovsky, A.M.1    Maier, L.M.2    Baecher-Allan, C.3    Anderson, A.C.4    Anderson, D.E.5
  • 18
    • 23844549973 scopus 로고    scopus 로고
    • Notch ligands Deltalike1, Delta-like4 and Jagged1 differentially regulate activation of peripheral T helper cells
    • Rutz S, Mordmuller B, Sakano S, Scheffold A. Notch ligands Deltalike1, Delta-like4 and Jagged1 differentially regulate activation of peripheral T helper cells. Eur J Immunol. 2005;35:2443-2451.
    • (2005) Eur J Immunol , vol.35 , pp. 2443-2451
    • Rutz, S.1    Mordmuller, B.2    Sakano, S.3    Scheffold, A.4
  • 19
    • 34447254518 scopus 로고    scopus 로고
    • CD8-DCs induce IL-12-independent Th1 differentiation through Delta 4 Notch-like ligand in response to bacterial LPS
    • Skokos D, Nussenzweig MC. CD8-DCs induce IL-12-independent Th1 differentiation through Delta 4 Notch-like ligand in response to bacterial LPS. J Exp Med. 2007;204:1525-1531.
    • (2007) J Exp Med , vol.204 , pp. 1525-1531
    • Skokos, D.1    Nussenzweig, M.C.2
  • 20
    • 57449117256 scopus 로고    scopus 로고
    • Notch ligand Delta-like4 inhibits the development of murine experimental allergic conjunctivitis
    • Fukushima A, Sumi T, Ishida W, et al. Notch ligand Delta-like4 inhibits the development of murine experimental allergic conjunctivitis. Immunol Lett. 2008;121:140-147.
    • (2008) Immunol Lett , vol.121 , pp. 140-147
    • Fukushima, A.1    Sumi, T.2    Ishida, W.3
  • 21
    • 44849096172 scopus 로고    scopus 로고
    • Delta-like 1 is essential for the maintenance of marginal zone B cells in normal mice but not in autoimmune mice
    • Moriyama Y, Sekine C, Koyanagi A, et al. Delta-like 1 is essential for the maintenance of marginal zone B cells in normal mice but not in autoimmune mice. Int Immunol. 2008;20:763-773.
    • (2008) Int Immunol , vol.20 , pp. 763-773
    • Moriyama, Y.1    Sekine, C.2    Koyanagi, A.3
  • 22
    • 44649146027 scopus 로고    scopus 로고
    • Experimental autoimmune uveoretinitis in the rat and mouse
    • Chapter 15:Unit 15.6
    • Caspi RR. Experimental autoimmune uveoretinitis in the rat and mouse. Curr Protoc Immunol. 2003; Chapter 15:Unit 15.6.
    • (2003) Curr Protoc Immunol
    • Caspi, R.R.1
  • 23
    • 78650310810 scopus 로고    scopus 로고
    • The expanding family of innate lymphoid cells: Regulators and effectors of immunity and tissue remodeling
    • Spits H, Di Santo JP. The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling. Nat Immunol. 2011;12:21-27.
    • (2011) Nat Immunol , vol.12 , pp. 21-27
    • Spits, H.1    di Santo, J.P.2
  • 26
    • 0036909508 scopus 로고    scopus 로고
    • Diminution of experimental autoimmune uveoretinitis (EAU) in mice depleted of NK cells
    • Kitaichi N, Kotake S, Morohashi T, Onoé K, Ohno S, Taylor AW. Diminution of experimental autoimmune uveoretinitis (EAU) in mice depleted of NK cells. J Leukoc Biol. 2002;72:1117-1121.
    • (2002) J Leukoc Biol , vol.72 , pp. 1117-1121
    • Kitaichi, N.1    Kotake, S.2    Morohashi, T.3    Onoé, K.4    Ohno, S.5    Taylor, A.W.6
  • 27
    • 58149277740 scopus 로고    scopus 로고
    • Activation of invariant NKT-cells ameliorates experimental ocular autoimmunity by a mechanism involving innate IFN-gamma production and dampening of the adaptive Th1 and Th17 responses
    • Grajewski RS, Hansen AM, Agarwal RK, et al. Activation of invariant NKT-cells ameliorates experimental ocular autoimmunity by a mechanism involving innate IFN-gamma production and dampening of the adaptive Th1 and Th17 responses. J Immunol. 2008; 181:4791-4797.
    • (2008) J Immunol , vol.181 , pp. 4791-4797
    • Grajewski, R.S.1    Hansen, A.M.2    Agarwal, R.K.3
  • 28
    • 78851469543 scopus 로고    scopus 로고
    • Invariant NKT-cells regulate experimental autoimmune uveitis through inhibition of Th17 differentiation
    • Oh K, Byoun OJ, Ham DI, Kim YS, Lee DS. Invariant NKT-cells regulate experimental autoimmune uveitis through inhibition of Th17 differentiation. Eur J Immunol. 2011;41:392-402.
    • (2011) Eur J Immunol , vol.41 , pp. 392-402
    • Oh, K.1    Byoun, O.J.2    Ham, D.I.3    Kim, Y.S.4    Lee, D.S.5
  • 29
    • 78650642332 scopus 로고    scopus 로고
    • Notch ligand delta-like 4 regulates development and pathogenesis of allergic airway responses by modulating IL-2 production and Th2 immunity
    • Jang S, Schaller M, Berlin AA, Lukacs NW. Notch ligand delta-like 4 regulates development and pathogenesis of allergic airway responses by modulating IL-2 production and Th2 immunity. J Immunol. 2010;185:5835-5844.
    • (2010) J Immunol , vol.185 , pp. 5835-5844
    • Jang, S.1    Schaller, M.2    Berlin, A.A.3    Lukacs, N.W.4
  • 31
    • 42249084849 scopus 로고    scopus 로고
    • Either a Th17 or a Th1 effector response can drive autoimmunity: Conditions of disease induction affect dominant effector category
    • Luger D, Silver PB, Tang J, et al. Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category. J Exp Med. 2008;205:799-810.
    • (2008) J Exp Med , vol.205 , pp. 799-810
    • Luger, D.1    Silver, P.B.2    Tang, J.3
  • 32
    • 67649216137 scopus 로고    scopus 로고
    • Regulation of T-cell activation by Notch ligand, DLL4, promotes IL-17 production and Rorc activation
    • Mukherjee S, Schaller MA, Neupane R, Kunkel SL, Lukacs NW. Regulation of T-cell activation by Notch ligand, DLL4, promotes IL-17 production and Rorc activation. J Immunol. 2009;182:7381-7388.
    • (2009) J Immunol , vol.182 , pp. 7381-7388
    • Mukherjee, S.1    Schaller, M.A.2    Neupane, R.3    Kunkel, S.L.4    Lukacs, N.W.5
  • 33
    • 77956107505 scopus 로고    scopus 로고
    • Ameliorating effects of anti-Dll4 mAb on Theiler's murine encephalomyelitis virusinduced demyelinating disease
    • Takeichi N, Yanagisawa S, Kaneyama T, et al. Ameliorating effects of anti-Dll4 mAb on Theiler's murine encephalomyelitis virusinduced demyelinating disease. Int Immunol. 2010;22:729-738.
    • (2010) Int Immunol , vol.22 , pp. 729-738
    • Takeichi, N.1    Yanagisawa, S.2    Kaneyama, T.3
  • 34
    • 38349075227 scopus 로고    scopus 로고
    • Notch signaling is activated by TLR stimulation and regulates macrophage functions
    • Palaga T, Buranaruk C, Rengpipat S, et al. Notch signaling is activated by TLR stimulation and regulates macrophage functions. Eur J Immunol. 2008;38:174-183.
    • (2008) Eur J Immunol , vol.38 , pp. 174-183
    • Palaga, T.1    Buranaruk, C.2    Rengpipat, S.3
  • 35
    • 58849108569 scopus 로고    scopus 로고
    • Notch signaling induces a distinct cytokine profile in dendritic cells that supports T-cell-mediated regulation and IL-2-dependent IL-17 production
    • Bugeon L, Gardner LM, Rose A, Gentle M, Dallman MJ. Notch signaling induces a distinct cytokine profile in dendritic cells that supports T-cell-mediated regulation and IL-2-dependent IL-17 production. J Immunol. 2008;181:8189-8193.
    • (2008) J Immunol , vol.181 , pp. 8189-8193
    • Bugeon, L.1    Gardner, L.M.2    Rose, A.3    Gentle, M.4    Dallman, M.J.5
  • 36
    • 79960752111 scopus 로고    scopus 로고
    • Interleukin-33 suppresses Notch ligand expression and prevents goblet cell depletion in dextran sulfate sodium-induced colitis
    • Imaeda H, Andoh A, Aomatsu T, et al. Interleukin-33 suppresses Notch ligand expression and prevents goblet cell depletion in dextran sulfate sodium-induced colitis. Int J Mol Med. 2011; 28: 573-578.
    • (2011) Int J Mol Med , vol.28 , pp. 573-578
    • Imaeda, H.1    Andoh, A.2    Aomatsu, T.3
  • 37
    • 22144492615 scopus 로고    scopus 로고
    • Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21
    • Minter LM, Turley DM, Das P, et al. Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21. Nat Immunol. 2005;6:680-688.
    • (2005) Nat Immunol , vol.6 , pp. 680-688
    • Minter, L.M.1    Turley, D.M.2    Das, P.3
  • 38
    • 42149177242 scopus 로고    scopus 로고
    • Notch3 inhibition in myelin-reactive T-cells down-regulates protein kinase C theta and attenuates experimental autoimmune encephalomyelitis
    • Jurynczyk M, Jurewicz A, Raine CS, Selmaj K. Notch3 inhibition in myelin-reactive T-cells down-regulates protein kinase C theta and attenuates experimental autoimmune encephalomyelitis. J Immunol. 2008;180:2634-2640.
    • (2008) J Immunol , vol.180 , pp. 2634-2640
    • Jurynczyk, M.1    Jurewicz, A.2    Raine, C.S.3    Selmaj, K.4


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