Error-prone translesion synthesis past DNA-peptide cross-links conjugated to the major groove of DNA via C5 of thymidine

Journal of Biological Chemistry

Volumn 290, Issue 2, 2015, Pages 775-787

  Wickramaratne, Susith ^a,b   Boldry, Emily J ^a,b   Buehler, Charles ^b   Wang, Yen Chih ^b   Distefano, Mark D ^a,b   Tretyakova, Natalia Y ^a,b  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IONIZING RADIATION; OXYGEN; PEPTIDES; POLYMERS; PROTEINS; REPAIR;

CATALYTIC EFFICIENCIES; DNA METHYLTRANSFERASES; DNA-PEPTIDE CONJUGATES; NUCLEOTIDE EXCISION REPAIR; REACTIVE OXYGEN SPECIES; STEADY-STATE KINETICS; TRANSLESION SYNTHESIS; TRANSLESION SYNTHESIS POLYMERASE;

DNA;

COPPER; DNA; DNA METHYLTRANSFERASE INHIBITOR; DNA POLYMERASE; PEPTIDE; REACTIVE OXYGEN METABOLITE; THYMIDINE; DNA ADDUCT; DNA DIRECTED DNA POLYMERASE;

ARTICLE; CATALYSIS; CONJUGATION; CYCLOADDITION; DNA CROSS LINKING; DNA DAMAGE; DNA STRUCTURE; ERROR; FRAMESHIFT MUTATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN DNA BINDING; STEADY STATE; SYNTHESIS; TANDEM MASS SPECTROMETRY; CHEMISTRY; CLICK CHEMISTRY; DNA ADDUCT; DNA REPAIR; DNA REPLICATION; GENETICS; HUMAN; KINETICS; METABOLISM; NEOPLASM; PATHOLOGY;

CLICK CHEMISTRY; DNA ADDUCTS; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; HUMANS; KINETICS; NEOPLASMS; PEPTIDES; REACTIVE OXYGEN SPECIES; TANDEM MASS SPECTROMETRY; THYMIDINE;

EID: 84920973951     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.613638     Document Type: Article

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