Replication past the N5-methyl-formamidopyrimidine lesion of deoxyguanosine by DNA polymerases and an improved procedure for sequence analysis of in vitro bypass products by mass spectrometry

Chemical Research in Toxicology

Volumn 22, Issue 6, 2009, Pages 1086-1095

  Christov, Plamen P ^a   Angel, Karen C ^a,b   Guengerich, F Peter ^a,b   Rizzo, Carmelo J ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; CYTOSINE; DEOXYGUANOSINE; DNA DIRECTED DNA POLYMERASE BETA; DNA FRAGMENT; DNA POLYMERASE; DNA POLYMERASE 4; GUANINE; N 5 METHYL FORMAMIDOPYRIMIDINE; N 6 (2 DEOXY DEXTRO ERYTHRO PENTOFURANOSYL) 2,6 DIAMINO 3,4 DIHYDRO 4 OXO 5 N METHYLFORMAMIDOPYRIMIDINE; OLIGONUCLEOTIDE; PRIMER DNA; PYRIMIDINE DERIVATIVE; STREPTAVIDIN; THYMINE; UNCLASSIFIED DRUG; BIOTIN; DNA DIRECTED DNA POLYMERASE; DRUG DERIVATIVE; FORMAMIDE DERIVATIVE;

ARTICLE; DNA CLEAVAGE; DNA PURIFICATION; DNA REPLICATION; DNA SEQUENCE; ELECTROSPRAY MASS SPECTROMETRY; ESCHERICHIA COLI; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NUCLEOTIDE METABOLISM; QUANTITATIVE ANALYSIS; STEADY STATE; SULFOLOBUS SOLFATARICUS; BIOSYNTHESIS; CHEMISTRY; DNA DAMAGE; ENZYMOLOGY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; KINETICS; METABOLISM; NUCLEOTIDE SEQUENCE; SYNTHESIS; TANDEM MASS SPECTROMETRY;

ESCHERICHIA COLI; SULFOLOBUS SOLFATARICUS;

BASE SEQUENCE; BIOTIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYGUANOSINE; DNA DAMAGE; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; ESCHERICHIA COLI; FORMAMIDES; KINETICS; OLIGONUCLEOTIDES; SEQUENCE ANALYSIS, DNA; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STREPTAVIDIN; SULFOLOBUS SOLFATARICUS; TANDEM MASS SPECTROMETRY;

EID: 67449103244     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx900047c     Document Type: Article

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