Oxidative DNA adducts and DNA-protein cross-links are the major DNA lesions induced by arsenite

Environmental Health Perspectives

Volumn 110, Issue SUPPL. 5, 2002, Pages 753-756

  Bau, Da Tian ^a   Wang, Tsu Shing ^a   Chung, Chiao Hui ^a   Wang, Alexander S S ^a   Jan, Kun Yan ^a  

^a ACADEMIA SINICA   (Taiwan)

Author keywords

Arsenic; Comet assay; DNA damage; Hypochlorous acid; Nitric oxide; Peroxynitrite; Reactive oxygen species; Thymine glycol

Indexed keywords

4 AMINOBENZOIC ACID DERIVATIVE; ARSENIC TRIOXIDE; CALCIMYCIN; CALCIUM; CARCINOGEN; DIETHYLDITHIOCARBAMIC ACID; DNA; DNA GLYCOSYLTRANSFERASE; ENDONUCLEASE; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GUANINE; MYELOPEROXIDASE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; OXIDIZING AGENT; PROTEINASE K; SALICYLHYDROXAMIC ACID;

ACUTE TOXICITY; ANIMAL CELL; ARSENIC POISONING; ARTICLE; CARCINOGENICITY; CELL SPECIFICITY; CELL TYPE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA ADDUCT; DNA CROSS LINKING; DNA DAMAGE; DNA STRAND BREAKAGE; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; MUTAGENICITY; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; SMOOTH MUSCLE FIBER; TARGET CELL; TARGET ORGAN; UMBILICAL VEIN; VASCULAR SMOOTH MUSCLE;

ANIMALIA;

EID: 0036801404     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.02110s5753     Document Type: Article

References (25)

1. Wang TS, Hsu TY, Chung CH, Wang ASS, Bau DT, Jan KY. Arsenite induces oxidative DNA adducts and DNA-protein cross-links in mammalian cells. Free Radic Biol Med 31:321-330 (2001).
2. Lynn S, Gurr JR, Lai HT, Jan KY. NADH oxidase activation is involved in arsenite-induced oxidative DNA damage in human vascular smooth muscle cells. Circ Res 86:514-519 (2000).
3. Li D, Firozi PF, Chang P. Wang LE, Xiong P, Sturgis EM, Eicher SA, Spitz MR, Hong WK, Wei Q. In vitro BPDE-induced DNA adducts in peripheral lymphocytes as a risk factor for squamous cell carcinoma of the head and neck. Int J Cancer 93:436-440 (2001).
4. Pi J, Kumagai Y, Sun G, Yamauchi H, Yoshida T, Iso H, Endo A, Yu L, Yuki K, Miyauchi T, et al. Decreased serum concentrations of nitric oxide metabolites among Chinese in an endemic area of chronic arsenic poisoning in inner Mongolia. Free Radic Biol Med 28:1137-1142 (2000).
5. Liu Y, Guyton KZ, Gorospe M, Xu Q, Lee JC, Holbrook NJ. Differential activation of ERK JNK/SAPK and P38/CSBP/RK map kinase family members during the cellular response to arsenite. Free Radic Biol Med 21:771-781 (1996).
6. Cavigelli M, Li WW, Lin A, Su B, Yoshioka K, Karin M. The tumor promoted arsenite stimulates AP-1 activity by inhibiting in a JNK phosphatase. EMBO J 15:6269-6279 (1996).
7. Simeonova PP, Wang S, Toriuma W, Kommineni V, Matheson J, Unimye N, Kayama F, Harki D, Ding M, Vallyathan V, et al. Arsenic mediates cell proliferation and gene expression in the bladder epithelium: association with activating protein-1 transactivation. Cancer Res 60:3445-3453 (2000).
8. Wiencke JK, Yager JW, Varkonyi A, Hultner M, Lutze LH. Study of arsenic mutagenesis using the plasmid shuttle vector pZ189 propagated in DNA repair proficient human cells. Mutant Res 386:335-344 (1997).
9. Hei TK, Liu SX, Waldren C. Mutagenicity of arsenic in mammalian cells: role of reactive oxygen species. Proc Natl AcadSci USA95:8103-8107 (1998).
10. Sunaga N, Kohno T, Shinmura K, Saitoh T, Matsuda T, Saito R, Yokota J. OGG1 protein suppresses G:C→T:A mutation in a shuttle vector containing 8-hydroxyguanine in human cells. Carcinogenesis 22(9):1355-1362 (2001).
11. Nickoloff JA, Spirio LN, Reynolds RJ. A comparison of calcium phosphate coprecipiation and electroporation. Implications for studis on the genetic effects of DNA damage. Mol Biotechnol 10(2):93-101 (1998).
12. Sarker AH, IkedaS, Nakano H, Terato H, Ide H, Imai K, Akiyama K, Tsutsui K, Bo Z, Kubo K, et al. Cloning and characterization of a mouse homologue (mNthl1) of Escherichia coli endonuclease III. J Mol Biol 282(4):761-774 (1998).
13. Unpublished results.
14. Ames BN. Mutagenesis and carcinogenesis: endogenous and exogenous factors. Environ Mol Mutagen 14(suppl 16): 66-77 (1989).
15. Wang TS, Chung CH, Wang ASS, Bau DT, Samikkannu T, Jan KY, Cheng YM, Lee TC. Endonuclease III, Formamidopyrimidine-DNA glycosylas, and proteinase K additively enhance arsenic-induced DNA strand breaks in human cells. Chem Res Toxicol (in press).
16. Wang TS, Shu YF, Liu YC, Jan KY, Huang H. Glutathione peroxidase and catalase modulate the genotoxicity of arsenite. Toxicology 121:229-237 (1997).
17. Lynn S, Shiung JN, Gurr JR, Jan KY. Arsenite stimulates poly(ADP)-ribosylation by generation of nitric oxide. Free Radic Biol Med 24:442-449 (1998).
18. Gurr JR, Liu F, Lynn S. Jan KY. Calcium-dependent nitric oxide production is involved in arsenite-indiced micronuclei. Mutat Res Genet Toxicol Environ Mutag 416:137-148 (1998).
19. Liu F, Jan KY. DNA damage in arsenite- and cadmium-treated bovine aortic endothelial cells. Free Radic Biol Med 28:55-63 (2000).
20. Whiteman M, Jenner A, Halliwell B. 8-Chloroadenine: a novel product formed from hypochlorous acid-induced damage to a calf thymus DNA. Biomarkers 4:303-310 (1999).
21. Spencer JPE, Whiteman M, Jenner A, Halliwell B. Nitrite-induced deamination and hypochlorite-induced oxidation of DNA in intact human respiratory tract epithelial cells. Free Radic Biol Med 28:1039-1050 (2000).
22. Hirata RK, Chen ST, Weil SC. Expression of granule protein mRNAs in acute promyelocytic leukemia. Hematol Pathol 7:225-238 (1993).
23. Gregoire C, Welch H, Astarie DC, Maridonneau PI. Expression of azurophil and specific granule protein during differentiation of NB4 cells in neutrophils. J Cell Physiol 175:203-210 (1998).
24. Hartman A, Speit G. Comparative investigations of the genotoxic effects of metals in the single cells gell (SCG) assay and the sister chromatid exhange (SCE) test. Environ Mol Mutagen 23:299-305 (1994).
25. Costa M, Zhitkovich A, Toniolo P. DNA-protein cross-links in welders: molecular implications. Cancer Res 53:460-463 (1993).