Translesion synthesis past the C8- and N2-deoxyguanosine adducts of the dietary mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in the NarI recognition sequence by prokaryotic DNA polymerases

Chemical Research in Toxicology

Volumn 19, Issue 11, 2006, Pages 1506-1517

  Stover, James S ^a   Chowdhury, Goutam ^b   Zang, Hong ^b   Guengerich, F Peter ^b   Rizzo, Carmelo J ^a,b  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 3 METHYLIMIDAZO[4,5 F]QUINOLINE; BACTERIAL PROTEIN; DNA; DNA DIRECTED DNA POLYMERASE ALPHA; DNA POLYMERASE; DNA POLYMERASE 4; MUTAGENIC AGENT; PROTEIN NARI; UNCLASSIFIED DRUG;

ARTICLE; CARCINOGENICITY; COOKING; DIETARY INTAKE; DNA ADDUCT; DNA REPLICATION; ENZYME ANALYSIS; ESCHERICHIA COLI; FRAMESHIFT MUTATION; IN VITRO STUDY; MEAT; MOLECULAR RECOGNITION; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN MODIFICATION; SULFOLOBUS SOLFATARICUS; TANDEM MASS SPECTROMETRY;

BACTERIA; COOKERY; DEOXYGUANOSINE; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DNA ADDUCTS; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; GENE DELETION; HEAT; MOLECULAR STRUCTURE; MUTAGENS; OLIGONUCLEOTIDES; PROKARYOTIC CELLS; QUINOLINES;

ANIMALIA; ESCHERICHIA COLI; PROKARYOTA; SULFOLOBUS SOLFATARICUS;

EID: 33845270444     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx0601455     Document Type: Article

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