Effect of transporter inhibition on the distribution of cefadroxil in rat brain

Fluids and Barriers of the CNS

Volumn 11, Issue 1, 2014, Pages

  Chen, Xiaomei ^a,b   Loryan, Irena ^b   Payan, Maryam ^b,c   Keep, Richard F ^d   Smith, David E ^a   Hammarlund Udenaes, Margareta ^b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UPPSALA UNIVERSITY   (Sweden)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Blood brain barrier; Blood cerebrospinal fluid barrier; Brain slice; Cefadroxil; Intracerebral microdialysis; Multidrug resistance associated proteins; Organic anion transporters; Organic anion transporting polypeptides; Peptide transporter 2; Probenecid

Indexed keywords

CEFADROXIL; MULTIDRUG RESISTANCE PROTEIN; ORGANIC ANION TRANSPORTER; ORGANIC ANION TRANSPORTING POLYPEPTIDE; POLYPEPTIDE; PROBENECID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BRAIN HOMOGENATE; BRAIN SLICE; CEREBROSPINAL FLUID; CONTROLLED STUDY; DRUG ADSORPTION; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG TRANSPORT; EXTRACELLULAR FLUID; IN VITRO STUDY; INTRACELLULAR FLUID; MALE; MEAN RESIDENCE TIME; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; VOLUME OF DISTRIBUTION;

EID: 84920813141     PISSN: 20458118     EISSN: 20458118     Source Type: Journal    
DOI: 10.1186/2045-8118-11-25     Document Type: Article

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