Peptide and peptide analog transport systems at the blood-CSF barrier

Advanced Drug Delivery Reviews

Volumn 56, Issue 12, 2004, Pages 1765-1791

  Smith, David E ^a   Johanson, Conrad E ^b   Keep, Richard F ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b RHODE ISLAND HOSPITAL   (United States)

Author keywords

Central nervous system; Choroid plexus; Drug delivery; Drug efflux; Hormones; Neuropeptides; PEPT2; Peptide transporters; Peptidomimetics; Proton coupled oligopeptide transporters

Indexed keywords

CEREBROSPINAL FLUID (CSF); OLIGOPEPTIDES; XENOBIOTICS;

BRAIN; DETOXIFICATION; DRUG DOSAGE; METABOLISM; NEUROLOGY;

BLOOD;

BETA LACTAM ANTIBIOTIC; CARRIER PROTEIN; CEFADROXIL; CEFALEXIN; CEFALORIDINE; CEFALOTIN; CEFEPIME; CEFOTAXIME; CEFTIZOXIME; CEFTRIAXONE; CEFUROXIME; CEPHALOSPORIN; CYSTATIN; GROWTH FACTOR; INSULIN; LATAMOXEF; LEPTIN; NEUROPEPTIDE; OLIGOPEPTIDE; PEPTIDE; POLYPEPTIDE; PROLACTIN; PROTON; TRANSFORMING GROWTH FACTOR BETA;

BASOLATERAL MEMBRANE; BLOOD BRAIN BARRIER; BLOOD CEREBROSPINAL FLUID BARRIER; BRAIN REGION; CENTRAL NERVOUS SYSTEM DISEASE; CEREBROSPINAL FLUID; CEREBROSPINAL FLUID FLOW; CHOROID PLEXUS; DIFFUSION; DRUG DISPOSITION; DRUG TRANSPORT; EPITHELIUM; HOMEOSTASIS; HUMAN; MOLECULAR BIOLOGY; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MODEL; NONHUMAN; NUCLEOTIDE SEQUENCE; PEPTIDE SYNTHESIS; PHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN TRANSPORT; REVIEW; TRANSGENIC MOUSE;

ANIMALS; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; CEREBROSPINAL FLUID; CHOROID PLEXUS; HUMANS; MEMBRANE TRANSPORT PROTEINS; PEPTIDES;

EID: 1942452552     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.addr.2004.07.008     Document Type: Review

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