Experiments on the role of deleterious mutations as stepping stones in adaptive evolution

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 34, 2013, Pages

  Covert III, Arthur W ^a,b,c   Lenski, Richard E ^a,d   Wilke, Claus O ^a,c   Ofria, Charles ^a,b  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b Michigan State University   (United States)

^c UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^d Michigan State University   (United States)

Author keywords

Epistasis; Experimental evolution; Genetic drift

Indexed keywords

ARTICLE; CONTROLLED STUDY; DELETION MUTANT; EVOLUTIONARY ADAPTATION; GENOTYPE; MUTATION RATE; POINT MUTATION; POPULATION SIZE; PRIORITY JOURNAL;

EPISTASIS; EXPERIMENTAL EVOLUTION; GENETIC DRIFT;

ADAPTATION, BIOLOGICAL; BIOLOGICAL EVOLUTION; COMPUTER SIMULATION; GENETIC FITNESS; MODELS, GENETIC; MUTATION; STATISTICS, NONPARAMETRIC;

EID: 84882790991     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1313424110     Document Type: Article

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