The hedgehog pathway effector smoothened exhibits signaling competency in the absence of ciliary accumulation

Chemistry and Biology

Volumn 21, Issue 12, 2014, Pages 1680-1689

  Fan, Chih Wei ^a   Chen, Baozhi ^a   Franco, Irene ^c   Lu, Jianming ^b   Shi, Heping ^b   Wei, Shuguang ^b   Wang, Changguang ^b   Wu, Xiaofeng ^a   Tang, Wei ^a   Roth, Michael G ^b   Williams, Noelle S ^b   Hirsch, Emilio ^c   Chen, Chuo ^b   Lum, Lawrence ^a  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF TURIN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE C2ALPHA; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG; G PROTEIN COUPLED RECEPTOR;

ARTICLE; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; EMBRYO; EUKARYOTIC FLAGELLUM; GENE MUTATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; ONCOGENE; PROTEIN DEPLETION; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; CHEMICAL STRUCTURE; METABOLISM; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE;

ERINACEIDAE;

ANIMALS; CELL LINE; CILIA; HEDGEHOG PROTEINS; HUMANS; MODELS, MOLECULAR; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 84919908650     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2014.10.013     Document Type: Article

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