PI3K class II α controls spatially restricted endosomal PtdIns3P and Rab11 activation to promote primary cilium function

Developmental Cell

Volumn 28, Issue 6, 2014, Pages 647-658

  Franco, Irene ^a   Gulluni, Federico ^a   Campa, Carlo C ^a   Costa, Carlotta ^a,f   Margaria, JeanPiero ^a   Ciraolo, Elisa ^a   Martini, Miriam ^a   Monteyne, Daniel ^b   De Luca, Elisa ^a   Germena, Giulia ^a   Posor, York ^c   Maffucci, Tania ^d   Marengo, Stefano ^a   Haucke, Volker ^c   Falasca, Marco ^d   Perez Morga, David ^b   Boletta, Alessandra ^e   Merlo, Giorgio R ^a   Hirsch, Emilio ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^c LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^d QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^e SAN RAFFAELE HOSPITAL   (Italy)

^f HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE CLASS 2 ALPHA; PHOSPHATIDYLINOSITOL 3 PHOSPHATE; PROTEIN; RAB 8 PROTEIN; RAB11 PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG; PHOSPHATIDYLINOSITOL 4 PHOSPHATE 3 KINASE; SMOOTHENED PROTEIN; G PROTEIN COUPLED RECEPTOR; PIK3C2A PROTEIN, MOUSE; POLYPHOSPHOINOSITIDE; RAB PROTEIN; SMALL INTERFERING RNA; SMO PROTEIN, MOUSE; TFRC PROTEIN, MOUSE;

ANGIOGENESIS; ANIMAL EXPERIMENT; ARTICLE; CELL COMPARTMENTALIZATION; CELL FRACTIONATION; CELL FUNCTION; CELL MIGRATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO DEVELOPMENT; ENDOSOME; ENZYME ACTIVATION; EUKARYOTIC FLAGELLUM; GENE TRANSLOCATION; MOUSE; NONHUMAN; PERICENTRIOLAR RECYCLING ENDOCYTIC COMPARTMENT; PHENOTYPE; PRIMARY CILIUM FUNCTION; PRIORITY JOURNAL; RECYCLING; ANIMAL CELL; EMBRYO; PRIMARY CELL CULTURE; ANIMAL; ANIMAL EMBRYO; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL CULTURE; CELL MOTION; CYTOLOGY; FEMALE; FIBROBLAST; GENETICS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; KNOCKOUT MOUSE; MALE; METABOLISM; PHYSIOLOGY; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ERINACEIDAE;

ANIMALS; CELL MOVEMENT; CELLS, CULTURED; CILIA; EMBRYO, MAMMALIAN; ENDOSOMES; FEMALE; FIBROBLASTS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHATIDYLINOSITOL PHOSPHATES; PROTEIN TRANSPORT; RAB GTP-BINDING PROTEINS; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, TRANSFERRIN; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84897065629     PISSN: 15345807     EISSN: 18781551     Source Type: Journal    
DOI: 10.1016/j.devcel.2014.01.022     Document Type: Article

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