메뉴 건너뛰기




Volumn 16, Issue 9, 2014, Pages 841-851

Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transport

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CILIA; DINOPROSTONE; HEK293 CELLS; HUMANS; KUPFFER CELLS; MICE; MOLECULAR SEQUENCE DATA; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; PROTEIN TRANSPORT; RECEPTORS, PROSTAGLANDIN E, EP4 SUBTYPE; SIGNAL TRANSDUCTION; TRANSPORT VESICLES; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84906847849     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb3029     Document Type: Article
Times cited : (80)

References (58)
  • 1
    • 0033791318 scopus 로고    scopus 로고
    • Cyclooxygenases: Structural, cellular, and molecular biology
    • Smith, W. L., DeWitt, D. L. & Garavito, R. M. Cyclooxygenases: structural, cellular, and molecular biology. Annu. Rev. Biochem. 69, 145-182 (2000).
    • (2000) Annu. Rev. Biochem. , vol.69 , pp. 145-182
    • Smith, W.L.1    Dewitt, D.L.2    Garavito, R.M.3
  • 2
    • 0033403626 scopus 로고    scopus 로고
    • Cyclooxygenase-deficient mice. A summary of their characteristics and susceptibilities to inflammation and carcinogenesis
    • Langenbach, R., Loftin, C. D., Lee, C. & Tiano, H. Cyclooxygenase-deficient mice. A summary of their characteristics and susceptibilities to inflammation and carcinogenesis. Ann. N.Y. Acad. Sci. 889, 52-61 (1999).
    • (1999) Ann. N.Y. Acad. Sci. , vol.889 , pp. 52-61
    • Langenbach, R.1    Loftin, C.D.2    Lee, C.3    Tiano, H.4
  • 3
    • 0032823306 scopus 로고    scopus 로고
    • Prostanoid receptors: Structures, properties, and functions
    • Narumiya, S., Sugimoto, Y. & Ushikubi, F. Prostanoid receptors: structures, properties, and functions. Physiol. Rev. 79, 1193-1226 (1999).
    • (1999) Physiol. Rev. , vol.79 , pp. 1193-1226
    • Narumiya, S.1    Sugimoto, Y.2    Ushikubi, F.3
  • 4
    • 77951101203 scopus 로고    scopus 로고
    • The primary cilium: A signalling centre during vertebrate development
    • Goetz, S. C. & Anderson, K. V. The primary cilium: a signalling centre during vertebrate development. Nat. Rev. Genet. 11, 331-344 (2010).
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 331-344
    • Goetz, S.C.1    Anderson, K.V.2
  • 5
    • 63049116544 scopus 로고    scopus 로고
    • The vertebrate primary cilium in development, homeostasis, and disease
    • Gerdes, J. M., Davis, E. E. & Katsanis, N. The vertebrate primary cilium in development, homeostasis, and disease. Cell 137, 32-45 (2009).
    • (2009) Cell , vol.137 , pp. 32-45
    • Gerdes, J.M.1    Davis, E.E.2    Katsanis, N.3
  • 6
    • 34250012834 scopus 로고    scopus 로고
    • A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis
    • Nachury, M. V. et al. A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis. Cell 129, 1201-1213 (2007).
    • (2007) Cell , vol.129 , pp. 1201-1213
    • Nachury, M.V.1
  • 7
    • 43149102968 scopus 로고    scopus 로고
    • Elipsa is an early determinant of ciliogenesis that links the IFT particle to membrane-associated small GTPase Rab8
    • Omori, Y. et al. Elipsa is an early determinant of ciliogenesis that links the IFT particle to membrane-associated small GTPase Rab8. Nat. Cell Biol. 10, 437-444 (2008).
    • (2008) Nat. Cell Biol. , vol.10 , pp. 437-444
    • Omori, Y.1
  • 9
    • 63949088362 scopus 로고    scopus 로고
    • FGF signalling during embryo development regulates cilia length in diverse epithelia
    • Neugebauer, J. M., Amack, J. D., Peterson, A. G., Bisgrove, B. W. & Yost, H. J. FGF signalling during embryo development regulates cilia length in diverse epithelia. Nature 458, 651-654 (2009).
    • (2009) Nature , vol.458 , pp. 651-654
    • Neugebauer, J.M.1    Amack, J.D.2    Peterson, A.G.3    Bisgrove, B.W.4    Yost, H.J.5
  • 10
    • 84855433919 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling directly regulates Foxj1 expression and ciliogenesis in zebrafish Kupffer's vesicle
    • Caron, A., Xu, X. & Lin, X. Wnt/beta-catenin signaling directly regulates Foxj1 expression and ciliogenesis in zebrafish Kupffer's vesicle. Development 139, 514-524 (2012).
    • (2012) Development , vol.139 , pp. 514-524
    • Caron, A.1    Xu, X.2    Lin, X.3
  • 11
    • 78049341348 scopus 로고    scopus 로고
    • Notch signalling regulates left-right asymmetry through ciliary length control
    • Lopes, S. S. et al. Notch signalling regulates left-right asymmetry through ciliary length control. Development 137, 3625-3632 (2010).
    • (2010) Development , vol.137 , pp. 3625-3632
    • Lopes, S.S.1
  • 12
    • 38049150495 scopus 로고    scopus 로고
    • A role for the inositol kinase Ipk1 in ciliary beating and length maintenance
    • Sarmah, B., Winfrey, V. P., Olson, G. E., Appel, B. & Wente, S. R. A role for the inositol kinase Ipk1 in ciliary beating and length maintenance. Proc. Natl Acad. Sci. USA 104, 19843-19848 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 19843-19848
    • Sarmah, B.1    Winfrey, V.P.2    Olson, G.E.3    Appel, B.4    Wente, S.R.5
  • 13
    • 0037672533 scopus 로고    scopus 로고
    • The zebrafish nodal-related gene southpaw is required for visceral and diencephalic left-right asymmetry
    • Long, S., Ahmad, N. & Rebagliati, M. The zebrafish nodal-related gene southpaw is required for visceral and diencephalic left-right asymmetry. Development 130, 2303-2316 (2003).
    • (2003) Development , vol.130 , pp. 2303-2316
    • Long, S.1    Ahmad, N.2    Rebagliati, M.3
  • 14
    • 0034629325 scopus 로고    scopus 로고
    • Gridlock, an HLH gene required for assembly of the aorta in zebrafish
    • Zhong, T. P., Rosenberg, M., Mohideen, M. A., Weinstein, B. & Fishman, M. C. Gridlock, an HLH gene required for assembly of the aorta in zebrafish. Science 287, 1820-1824 (2000).
    • (2000) Science , vol.287 , pp. 1820-1824
    • Zhong, T.P.1    Rosenberg, M.2    Mohideen, M.A.3    Weinstein, B.4    Fishman, M.C.5
  • 15
    • 41349107158 scopus 로고    scopus 로고
    • Multidrug resistance protein 4 (MRP4/ABCC4): A versatile efflux transporter for drugs and signalling molecules
    • Russel, F. G., Koenderink, J. B. & Masereeuw, R. Multidrug resistance protein 4 (MRP4/ABCC4): a versatile efflux transporter for drugs and signalling molecules. Trends Pharmacol. Sci. 29, 200-207 (2008).
    • (2008) Trends Pharmacol. Sci. , vol.29 , pp. 200-207
    • Russel, F.G.1    Koenderink, J.B.2    Masereeuw, R.3
  • 16
    • 0032879904 scopus 로고    scopus 로고
    • MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs
    • Schuetz, J. D. et al. MRP4: a previously unidentified factor in resistance to nucleoside-based antiviral drugs. Nat. Med. 5, 1048-1051 (1999).
    • (1999) Nat. Med. , vol.5 , pp. 1048-1051
    • Schuetz, J.D.1
  • 17
    • 80052490064 scopus 로고    scopus 로고
    • Mammalian multidrug-resistance proteins (MRPs)
    • Slot, A. J., Molinski, S. V. & Cole, S. P. Mammalian multidrug-resistance proteins (MRPs). Essays Biochem. 50, 179-207 (2011).
    • (2011) Essays Biochem. , vol.50 , pp. 179-207
    • Slot, A.J.1    Molinski, S.V.2    Cole, S.P.3
  • 18
    • 33748665424 scopus 로고    scopus 로고
    • The ins and outs of drug transport
    • Schuldiner, S. The ins and outs of drug transport. Nature 144, 156-157 (2006).
    • (2006) Nature , vol.144 , pp. 156-157
    • Schuldiner, S.1
  • 19
    • 17244366458 scopus 로고    scopus 로고
    • Kupffer's vesicle is a ciliated organ of asymmetry in the zebrafish embryo that initiates left-right development of the brain, heart and gut
    • Essner, J. J., Amack, J. D., Nyholm, M. K., Harris, E. B. & Yost, H. J. Kupffer's vesicle is a ciliated organ of asymmetry in the zebrafish embryo that initiates left-right development of the brain, heart and gut. Development 132, 1247-1260 (2005).
    • (2005) Development , vol.132 , pp. 1247-1260
    • Essner, J.J.1    Amack, J.D.2    Nyholm, M.K.3    Harris, E.B.4    Yost, H.J.5
  • 20
    • 18844393668 scopus 로고    scopus 로고
    • Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis
    • Kramer-Zucker, A. G. et al. Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis. Development 132, 1907-1921 (2005).
    • (2005) Development , vol.132 , pp. 1907-1921
    • Kramer-Zucker, A.G.1
  • 21
    • 1942477305 scopus 로고    scopus 로고
    • The T box transcription factor no tail in ciliated cells controls zebrafish left-right asymmetry
    • Amack, J. D. & Yost, H. J. The T box transcription factor no tail in ciliated cells controls zebrafish left-right asymmetry. Curr. Biol. 14, 685-690 (2004).
    • (2004) Curr. Biol. , vol.14 , pp. 685-690
    • Amack, J.D.1    Yost, H.J.2
  • 22
    • 0043132421 scopus 로고    scopus 로고
    • The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs
    • Reid, G. et al. The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs. Proc. Natl Acad. Sci. USA 100, 9244-9249 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 9244-9249
    • Reid, G.1
  • 23
    • 84883144525 scopus 로고    scopus 로고
    • Human immunodeficiency virus protease inhibitors interact with ATP binding cassette transporter 4/multidrug resistance protein 4: A basis for unanticipated enhanced cytotoxicity
    • Fukuda, Y. et al. Human immunodeficiency virus protease inhibitors interact with ATP binding cassette transporter 4/multidrug resistance protein 4: a basis for unanticipated enhanced cytotoxicity. Mol. Pharmacol. 84, 361-371 (2013).
    • (2013) Mol. Pharmacol. , vol.84 , pp. 361-371
    • Fukuda, Y.1
  • 24
    • 31844446751 scopus 로고    scopus 로고
    • Functional importance of three basic residues clustered at the cytosolic interface of transmembrane helix 15 in the multidrug and organic anion transporter MRP1 (ABCC1)
    • Conseil, G., Deeley, R. G. & Cole, S. P. Functional importance of three basic residues clustered at the cytosolic interface of transmembrane helix 15 in the multidrug and organic anion transporter MRP1 (ABCC1). J. Biol. Chem. 281, 43-50 (2006).
    • (2006) J. Biol. Chem. , vol.281 , pp. 43-50
    • Conseil, G.1    Deeley, R.G.2    Cole, S.P.3
  • 25
    • 29944434200 scopus 로고    scopus 로고
    • Cyclooxygenase-1-derived PGE2 promotes cell motility via the G-protein-coupled EP4 receptor during vertebrate gastrulation
    • Cha, Y. I. et al. Cyclooxygenase-1-derived PGE2 promotes cell motility via the G-protein-coupled EP4 receptor during vertebrate gastrulation. Genes Dev. 20, 77-86 (2006).
    • (2006) Genes Dev. , vol.20 , pp. 77-86
    • Cha, Y.I.1
  • 26
    • 20344364611 scopus 로고    scopus 로고
    • Cyclooxygenase-1 signaling is required for vascular tube formation during development
    • Cha, Y. I., Kim, S. H., Solnica-Krezel, L. & Dubois, R. N. Cyclooxygenase-1 signaling is required for vascular tube formation during development. Dev. Biol. 282, 274-283 (2005).
    • (2005) Dev. Biol. , vol.282 , pp. 274-283
    • Cha, Y.I.1    Kim, S.H.2    Solnica-Krezel, L.3    Dubois, R.N.4
  • 27
    • 34250883337 scopus 로고    scopus 로고
    • Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis
    • North, T. E. et al. Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis. Nature 447, 1007-1011 (2007).
    • (2007) Nature , vol.447 , pp. 1007-1011
    • North, T.E.1
  • 28
    • 62149148156 scopus 로고    scopus 로고
    • Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration
    • Goessling, W. et al. Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration. Cell 136, 1136-1147 (2009).
    • (2009) Cell , vol.136 , pp. 1136-1147
    • Goessling, W.1
  • 29
    • 74449086803 scopus 로고    scopus 로고
    • Identification of signaling pathways regulating primary cilium length and flow-mediated adaptation
    • Besschetnova, T. Y. et al. Identification of signaling pathways regulating primary cilium length and flow-mediated adaptation. Curr. Biol. 20, 182-187 (2010).
    • (2010) Curr. Biol. , vol.20 , pp. 182-187
    • Besschetnova, T.Y.1
  • 30
    • 56749163207 scopus 로고    scopus 로고
    • Foxj1 transcription factors are master regulators of the motile ciliogenic program
    • Yu, X., Ng, C. P., Habacher, H. & Roy, S. Foxj1 transcription factors are master regulators of the motile ciliogenic program. Nat. Genet. 40, 1445-1453 (2008).
    • (2008) Nat. Genet. , vol.40 , pp. 1445-1453
    • Yu, X.1    Ng, C.P.2    Habacher, H.3    Roy, S.4
  • 31
    • 56749152216 scopus 로고    scopus 로고
    • The forkhead protein Foxj1 specifies node-like cilia in Xenopus and zebrafish embryos
    • Stubbs, J. L., Oishi, I., Belmonte, J. C. I. & Kintner, C. The forkhead protein Foxj1 specifies node-like cilia in Xenopus and zebrafish embryos. Nat. Genet. 40, 1454-1460 (2008).
    • (2008) Nat. Genet. , vol.40 , pp. 1454-1460
    • Stubbs, J.L.1    Oishi, I.2    Belmonte, J.C.I.3    Kintner, C.4
  • 32
    • 84863198374 scopus 로고    scopus 로고
    • MiR-129-3p controls cilia assembly by regulating CP110 and actin dynamics
    • Cao, J. et al. miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics. Nat. Cell Biol. 14, 697-706 (2012).
    • (2012) Nat. Cell Biol. , vol.14 , pp. 697-706
    • Cao, J.1
  • 33
    • 84872681810 scopus 로고    scopus 로고
    • Prostaglandin E2/EP4 signalling facilitates EP4 receptor externalization in primary sensory neurons in vitro and in vivo
    • St-Jacques, B. & Ma, W. Prostaglandin E2/EP4 signalling facilitates EP4 receptor externalization in primary sensory neurons in vitro and in vivo. Pain 154, 313-323 (2013).
    • (2013) Pain , vol.154 , pp. 313-323
    • St-Jacques, B.1    Ma, W.2
  • 34
    • 41349107244 scopus 로고    scopus 로고
    • THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia
    • Tran, P. V. et al. THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia. Nat. Genet. 40, 403-410 (2008).
    • (2008) Nat. Genet. , vol.40 , pp. 403-410
    • Tran, P.V.1
  • 35
    • 2942596578 scopus 로고    scopus 로고
    • Intraflagellar transport genes are essential for differentiation and survival of vertebrate sensory neurons
    • Tsujikawa, M. & Malicki, J. Intraflagellar transport genes are essential for differentiation and survival of vertebrate sensory neurons. Neuron 42, 703-716 (2004).
    • (2004) Neuron , vol.42 , pp. 703-716
    • Tsujikawa, M.1    Malicki, J.2
  • 36
    • 34248226331 scopus 로고    scopus 로고
    • Mast cells and eicosanoid mediators: A system of reciprocal paracrine and autocrine regulation
    • Boyce, J. A. Mast cells and eicosanoid mediators: a system of reciprocal paracrine and autocrine regulation. Immunol. Rev. 217, 168-185 (2007).
    • (2007) Immunol. Rev. , vol.217 , pp. 168-185
    • Boyce, J.A.1
  • 37
    • 77954652338 scopus 로고    scopus 로고
    • PGE(2) is a UVR-inducible autocrine factor for human melanocytes that stimulates tyrosinase activation
    • Starner, R. J., McClelland, L., Abdel-Malek, Z., Fricke, A. & Scott, G. PGE(2) is a UVR-inducible autocrine factor for human melanocytes that stimulates tyrosinase activation. Exp. Dermatol. 19, 682-684 (2010).
    • (2010) Exp. Dermatol. , vol.19 , pp. 682-684
    • Starner, R.J.1    McClelland, L.2    Abdel-Malek, Z.3    Fricke, A.4    Scott, G.5
  • 38
    • 79955765994 scopus 로고    scopus 로고
    • The type 3 adenylyl cyclase is required for novel object learning and extinction of contextual memory: Role of cAMP signaling in primary cilia
    • Wang, Z., Phan, T. & Storm, D. R. The type 3 adenylyl cyclase is required for novel object learning and extinction of contextual memory: role of cAMP signaling in primary cilia. J. Neurosci. 31, 5557-5561 (2011).
    • (2011) J. Neurosci. , vol.31 , pp. 5557-5561
    • Wang, Z.1    Phan, T.2    Storm, D.R.3
  • 39
    • 70449709536 scopus 로고    scopus 로고
    • Intraflagellar transport particle size scales inversely with flagellar length: Revisiting the balance-point length control model
    • Engel, B. D., Ludington, W. B. & Marshall, W. F. Intraflagellar transport particle size scales inversely with flagellar length: revisiting the balance-point length control model. J. Cell Biol. 187, 81-89 (2009).
    • (2009) J. Cell Biol. , vol.187 , pp. 81-89
    • Engel, B.D.1    Ludington, W.B.2    Marshall, W.F.3
  • 40
    • 33749024768 scopus 로고    scopus 로고
    • Mechanism of transport of IFT particles in C. Elegans cilia by the concerted action of kinesin-II and OSM-3 motors
    • Pan, X. et al. Mechanism of transport of IFT particles in C. elegans cilia by the concerted action of kinesin-II and OSM-3 motors. J. Cell Biol. 174, 1035-1045 (2006).
    • (2006) J. Cell Biol. , vol.174 , pp. 1035-1045
    • Pan, X.1
  • 41
    • 38149067307 scopus 로고    scopus 로고
    • Prostaglandin E2: Making more of your marrow
    • Lord, A. M., North, T. E. & Zon, L. I. Prostaglandin E2: making more of your marrow. Cell Cycle 6, 3054-3057 (2007).
    • (2007) Cell Cycle , vol.6 , pp. 3054-3057
    • Lord, A.M.1    North, T.E.2    Zon, L.I.3
  • 42
    • 0242321274 scopus 로고    scopus 로고
    • EP2 and EP4 prostanoid receptor signaling
    • Regan, J. W. EP2 and EP4 prostanoid receptor signaling. Life Sci. 74, 143-153 (2003).
    • (2003) Life Sci. , vol.74 , pp. 143-153
    • Regan, J.W.1
  • 43
    • 84893690881 scopus 로고    scopus 로고
    • Secreting and sensing the same molecule allows cells to achieve versatile social behaviors
    • Youk, H. & Lim, W. A. Secreting and sensing the same molecule allows cells to achieve versatile social behaviors. Science 343, 1242782 (2014).
    • (2014) Science , vol.343 , pp. 1242782
    • Youk, H.1    Lim, W.A.2
  • 44
    • 0034919019 scopus 로고    scopus 로고
    • Prostaglandin E2 activates the ciliary beat frequency of cultured human nasal mucosa via the second messenger cyclic adenosine monophosphate
    • Haxel, B. R., Schafer, D., Klimek, L. & Mann, W. J. Prostaglandin E2 activates the ciliary beat frequency of cultured human nasal mucosa via the second messenger cyclic adenosine monophosphate. Eur. Arch. Otorhinolaryngol. 258, 230-235 (2001).
    • (2001) Eur. Arch. Otorhinolaryngol. , vol.258 , pp. 230-235
    • Haxel, B.R.1    Schafer, D.2    Klimek, L.3    Mann, W.J.4
  • 45
    • 0032578564 scopus 로고    scopus 로고
    • Opposing actions of prostaglandins and oxytocin determine the onset of murine labor
    • Gross, G. A. et al. Opposing actions of prostaglandins and oxytocin determine the onset of murine labor. Proc. Natl Acad. Sci. USA 95, 11875-11879 (1998).
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 11875-11879
    • Gross, G.A.1
  • 46
    • 0035970022 scopus 로고    scopus 로고
    • Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2
    • Loftin, C. D. et al. Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2. Proc. Natl Acad. Sci. USA 98, 1059-1064 (2001).
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 1059-1064
    • Loftin, C.D.1
  • 47
    • 0028818913 scopus 로고
    • Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II
    • Dinchuk, J. E. et al. Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II. Nature 378, 406-409 (1995).
    • (1995) Nature , vol.378 , pp. 406-409
    • Dinchuk, J.E.1
  • 48
    • 0034662904 scopus 로고    scopus 로고
    • Coordinated regulation of fetal and maternal prostaglandins directs successful birth and postnatal adaptation in the mouse
    • Reese, J. et al. Coordinated regulation of fetal and maternal prostaglandins directs successful birth and postnatal adaptation in the mouse. Proc. Natl Acad. Sci. USA 97, 9759-9764 (2000).
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 9759-9764
    • Reese, J.1
  • 49
    • 84869069719 scopus 로고    scopus 로고
    • The spinocerebellar ataxia-associated gene Tau tubulin kinase 2 controls the initiation of ciliogenesis
    • Goetz, S. C., Liem, K. F. Jr & Anderson, K. V. The spinocerebellar ataxia-associated gene Tau tubulin kinase 2 controls the initiation of ciliogenesis. Cell 151, 847-858 (2012).
    • (2012) Cell , vol.151 , pp. 847-858
    • Goetz, S.C.1    Liem, Jr.K.F.2    Anderson, K.V.3
  • 50
    • 78651254549 scopus 로고    scopus 로고
    • The coiled-coil domain containing protein CCDC40 is essential for motile cilia function and left-right axis formation
    • Becker-Heck, A. et al. The coiled-coil domain containing protein CCDC40 is essential for motile cilia function and left-right axis formation. Nat. Genet. 43, 79-84 (2011).
    • (2011) Nat. Genet. , vol.43 , pp. 79-84
    • Becker-Heck, A.1
  • 52
    • 12644268233 scopus 로고    scopus 로고
    • A genetic screen for mutations affecting embryogenesis in zebrafish
    • Driever, W. et al. A genetic screen for mutations affecting embryogenesis in zebrafish. Development 123, 37-46 (1996).
    • (1996) Development , vol.123 , pp. 37-46
    • Driever, W.1
  • 53
    • 0035829517 scopus 로고    scopus 로고
    • Gridlock signalling pathway fashions the first embryonic artery
    • Zhong, T. P., Childs, S., Leu, J. P. & Fishman, M. C. Gridlock signalling pathway fashions the first embryonic artery. Nature 414, 216-220 (2001).
    • (2001) Nature , vol.414 , pp. 216-220
    • Zhong, T.P.1    Childs, S.2    Leu, J.P.3    Fishman, M.C.4
  • 54
    • 77951249099 scopus 로고    scopus 로고
    • Hedgehog signaling induces arterial endothelial cell formation by repressing venous cell fate
    • Williams, C. et al. Hedgehog signaling induces arterial endothelial cell formation by repressing venous cell fate. Dev. Biol. 341, 196-204 (2010).
    • (2010) Dev. Biol. , vol.341 , pp. 196-204
    • Williams, C.1
  • 55
    • 84880925260 scopus 로고    scopus 로고
    • Arl13b-regulated cilia activities are essential for polarized radial glial scaffold formation
    • Higginbotham, H. et al. Arl13b-regulated cilia activities are essential for polarized radial glial scaffold formation. Nat. Neurosci. 16, 1000-1007 (2013).
    • (2013) Nat. Neurosci. , vol.16 , pp. 1000-1007
    • Higginbotham, H.1
  • 56
    • 79953012240 scopus 로고    scopus 로고
    • Human bronchial smooth muscle cells express adenylyl cyclase isoforms 2, 4, and 6 in distinct membrane microdomains
    • Bogard, A. S., Xu, C. & Ostrom, R. S. Human bronchial smooth muscle cells express adenylyl cyclase isoforms 2, 4, and 6 in distinct membrane microdomains. J. Pharmacol. Exp. Ther. 337, 209-217 (2011).
    • (2011) J. Pharmacol. Exp. Ther. , vol.337 , pp. 209-217
    • Bogard, A.S.1    Xu, C.2    Ostrom, R.S.3
  • 57
    • 49649107855 scopus 로고    scopus 로고
    • Down-regulation of Na+/H+ exchanger regulatory factor 1 increases expression and function of multidrug resistance protein 4
    • Hoque, M. T. & Cole, S. P. Down-regulation of Na+/H+ exchanger regulatory factor 1 increases expression and function of multidrug resistance protein 4. Cancer Res. 68, 4802-4809 (2008).
    • (2008) Cancer Res. , vol.68 , pp. 4802-4809
    • Hoque, M.T.1    Cole, S.P.2
  • 58
    • 4344632950 scopus 로고    scopus 로고
    • Mrp4 confers resistance to topotecan and protects the brain from chemotherapy
    • Leggas, M. et al. Mrp4 confers resistance to topotecan and protects the brain from chemotherapy. Mol. Cell Biol. 24, 7612-7621 (2004).
    • (2004) Mol. Cell Biol. , vol.24 , pp. 7612-7621
    • Leggas, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.