Capping of Aβ42 oligomers by small molecule inhibitors

Biochemistry

Volumn 53, Issue 50, 2014, Pages 7893-7903

  Fu, Ziao ^a   Aucoin, Darryl ^a   Ahmed, Mahiuddin ^a   Ziliox, Martine ^a   Van Nostrand, William E ^a   Smith, Steven O ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATOMIC FORCE MICROSCOPY; MOLECULES; NEURODEGENERATIVE DISEASES; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDES;

ALZHEIMER'S DISEASE; AMYLOID FIBRIL; LOW MOLECULAR WEIGHT; PEPTIDE INHIBITORS; PROTOFIBRILS; SMALL MOLECULE INHIBITOR; SMALL MOLECULES; WEAK INTERACTIONS;

OLIGOMERS;

AMYLOID BETA PROTEIN[1-42]; CURCUMIN; INDOMETACIN; MONOMER; OLIGOMER; PROTEIN INHIBITOR; RESVERATROL; SULINDAC SULFIDE; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); NONSTEROID ANTIINFLAMMATORY AGENT; PEPTIDE FRAGMENT; PROTEIN AGGREGATE; SULINDAC;

AMINO TERMINAL SEQUENCE; ARTICLE; ATOMIC FORCE MICROSCOPY; CONTROLLED STUDY; DRUG MECHANISM; DRUG PROTEIN BINDING; HETERONUCLEAR SINGLE QUANTUM COHERENCE; MOLECULAR SIZE; MOLECULAR WEIGHT; NITROGEN NUCLEAR MAGNETIC RESONANCE; OLIGOMERIZATION; PROTEIN AGGREGATION; PROTEIN MODIFICATION; PROTON NUCLEAR MAGNETIC RESONANCE; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; CHEMISTRY; HUMAN; PROTEIN TERTIARY STRUCTURE;

AMYLOID BETA-PEPTIDES; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CURCUMIN; HUMANS; INDOMETHACIN; MICROSCOPY, ATOMIC FORCE; PEPTIDE FRAGMENTS; PROTEIN AGGREGATES; PROTEIN STRUCTURE, TERTIARY; SULINDAC;

EID: 84919807754     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi500910b     Document Type: Article

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