Kinetics of amyloid β monomer-to-oligomer exchange by NMR relaxation

Journal of the American Chemical Society

Volumn 132, Issue 29, 2010, Pages 9948-9951

  Fawzi, Nicolas L ^a   Ying, Jinfa ^a   Torchia, Dennis A ^a   Clore, G Marius ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER'S DISEASE; COUPLED SPINS; DISORDERED REGIONS; FIRST-ORDER RATE CONSTANTS; HYDROPHOBIC REGIONS; KINETIC CHARACTERIZATION; LIFETIME BROADENING; MCCONNELL EQUATIONS; NMR RELAXATION; OLIGOMERIC STATE; PEPTIDE CHAIN; PROTEIN CONCENTRATIONS; PSEUDO-EQUILIBRIUM; RADIO-FREQUENCY FIELDS; SITE EXCHANGE; TOXIC SPECIES;

GLYCOPROTEINS; MAGNETIC FIELDS; OLIGOMERS; PEPTIDES; RATE CONSTANTS;

MONOMERS;

AMYLOID BETA PROTEIN; MONOMER; NITROGEN 15; OLIGOMER; PROTON;

ALZHEIMER DISEASE; ARTICLE; DIPOLE; ISOTOPE LABELING; KINETICS; MAGNETIC FIELD; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; TRANSMISSION ELECTRON MICROSCOPY;

AMYLOID BETA-PEPTIDES; BUFFERS; KINETICS; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDE FRAGMENTS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; SOLUTIONS;

EID: 77955819967     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja1048253     Document Type: Article

References (33)

1. Goedert, M.; Spillantini, M. G. Science 2006, 314, 777-781.
2. Querfurth, H. W.; LaFerla, F. M. New Engl. J. Med. 2010, 362, 329-344.
3. Walsh, D. M.; Selkoe, D. J. J. Neurochem. 2007, 101, 1172-1184.
4. Fukumoto, H.; Tokuda, T.; Kasai, T.; Ishigami, N.; Hidaka, H.; Kondo, M.; Allsop, D.; Nakagawa, M. FASEB J. 2010; 0:fj.09-150359v1 epub.
5. Pimplikar, S. W. Int. J. Biochem. Cell Biol. J 2009, 41, 1261-1268.
6. Serpell, L. C.; Fraser, P. E.; Sunde, M. Methods Enzymol. 1999, 309, 526-536.
7. (a) Paravastu, A. K.; Qahwash, I.; Leapman, R. D.; Meredith, S. C.; Tycko, R. Proc. Natl. Acad. Sci. U. S. A. 2009, 106, 7443-7448.
8. (b) Petkova, A. T.; Ishii, Y.; Balbach, J. J.; Antzutkin, O. N.; Leapman, R. D.; Delaglio, F.; Tycko, R. Proc. Natl. Acad. Sci. U. S. A. 2002, 99, 16742-16747.
9. (c) Petkova, A. T.; Leapman, R. D.; Guo, Z. H.; Yau, W. M.; Mattson, M. P.; Tycko, R. Science 2005, 307, 262-265.
10. Chen, B.; Thurber, K. R.; Shewmaker, F.; Wickner, R. B.; Tycko, R. Proc. Natl. Acad. Sci. U. S. A. 2009, 106, 14339-14344.
11. Luhrs, T.; Ritter, C.; Adrian, M.; Riek-Loher, D.; Bohrmann, B.; Doeli, H.; Schubert, D.; Riek, R. Proc. Natl. Acad. Sci. U. S. A. 2005, 102, 17342-17347.
12. (a) Bernstein, S. L.; Dupuis, N. F.; Lazo, N. D.; Wyttenbach, T.; Condron, M. M.; Bitan, G.; Teplow, D. B.; Shea, J. E.; Ruotolo, B. T.; Robinson, C. V.; Bowers, M. T. Nature Chem. 2009, 1, 326-331.
13. (b) Rahimi, F.; Shanmugam, A.; Bitan, G. Curr. Alzheimer Res. 2008, 5, 319-341.
14. (c) Yu, L.; et al. Biochemistry 2009, 48, 1870-1877.
15. Teplow, D. B.; Lazo, N. D.; Bitan, G.; Bernstein, S.; Wyttenbach, T.; Bowers, M. T.; Baumketner, A.; Shea, J. E.; Urbanc, B.; Cruz, L.; Borreguero, J.; Stanley, H. E. Acc. Chem. Res. 2006, 39, 635-45.
16. (a) Knowles, T. P.; Waudby, C. A.; Devlin, G. L.; Cohen, S. I.; Aguzzi, A.; Vendruscolo, M.; Terentjev, E. M.; Welland, M. E.; Dobson, C. M. Science 2009, 326, 1533-1537.
17. (b) Bellesia, G.; Shea, J. E. J. Chem. Phys. 2009, 131, 111102.
18. (v) Lee, C. F.; Loken, J.; Jean, L.; Vaux, D. J. Phys. Rev. E Stat. Nonlin. Soft Matter Phys. 2009, 80, 041906.
19. Hou, L. M.; Zagorski, M. G. J. Am. Chem. Soc. 2006, 128, 9260-9261.
20. Iwahara, J.; Tang, C.; Clore, G. M. J. Magn. Reson. 2007, 184, 185-195.
21. Yan, Y.; Wang, C. J. Mol. Biol. 2006, 364, 853-862.
22. Yan, Y.; Wang, C. J. Mol. Biol. 2007, 369, 909-916.
23. Almstedt, K.; Nystrom, S.; Nilsson, K. P.; Hammarstrom, P. Prion 2009, 3, 224-235.
24. Wang, C. Y.; Grey, M. J.; Palmer, A. G. J. Biomol. NMR 2001, 21, 361-366.
25. Mittermaier, A.; Kay, L. E. Science 2006, 312, 224-228.
26. (a) Clore, G. M. Mol. Biophys. 2008, 4, 1058-1069.
27. (b) Tang, C.; Iwahara, J.; Clore, G. M. Nature 2006, 444, 383-386.
28. (c) Tang, C.; Ghirlando, R.; Clore, G. M. J. Am. Chem. Soc. 2008, 130, 4048-4056.
29. Bodner, C. R.; Dobson, C. M.; Bax, A. J. Mol. Biol. 2009, 390, 775-790.
30. (a) McConnell, H. M. J. Chem. Phys. 1958, 28, 430-431.
31. (b) Helgstrand, M.; Hart, T.; Allard, P. J. Biomol. NMR 2000, 18, 49-63.
32. Petkova, A. T.; Yau, W. M.; Tycko, R. Biochemistry 2006, 45, 498-512.
33. Wu, K. P.; Baum, J. J. Am. Chem. Soc. 2010, 132, 5546-5547.