Germline Signals Deploy NHR-49 to Modulate Fatty-Acid β-Oxidation and Desaturation in Somatic Tissues of C. elegans

PLoS Genetics

Volumn 10, Issue 12, 2014, Pages

  Ratnappan, Ramesh ^a   Amrit, Francis R G ^a   Chen, Shaw Wen ^b   Gill, Hasreet ^a,d   Holden, Kyle ^a   Ward, Jordan ^c   Yamamoto, Keith R ^c   Olsen, Carissa P ^b   Ghazi, Arjumand ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b Fred Hutchinson Cancer Research Center   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HORMONE RECEPTOR; MESSENGER RNA; PEPTIDES AND PROTEINS; PROTEIN NHR 49; PROTEIN TCER 1; PROTEIN TCERG 1; TRANSCRIPTION FACTOR DAF 16; TRANSCRIPTION FACTOR FOXO; UNCLASSIFIED DRUG; CAENORHABDITIS ELEGANS PROTEIN; CELL RECEPTOR; DAF-16 PROTEIN, C ELEGANS; ELONGATION FACTOR; FATTY ACID; FORKHEAD TRANSCRIPTION FACTOR; NHR-49 PROTEIN, C ELEGANS; TCER-1 PROTEIN, C ELEGANS;

ADULT ANIMAL; AGING; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; FATTY ACID DESATURATION; FATTY ACID OXIDATION; FERTILITY; GENE OVEREXPRESSION; GERM LINE; LIFESPAN; LIPID HOMEOSTASIS; LIPOGENESIS; LONGEVITY; MITOCHONDRION; NHR 49 GENE; NONHUMAN; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SOMATIC CELL; ANIMAL; FEMALE; GENETICS; GERM CELL; LIPID METABOLISM; METABOLISM; OXIDATION REDUCTION REACTION; PHYSIOLOGY; REPRODUCTION; TRANSGENIC ANIMAL;

ANIMALIA; CAENORHABDITIS ELEGANS;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; FATTY ACIDS; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GERM CELLS; LIPID METABOLISM; LONGEVITY; OXIDATION-REDUCTION; PEPTIDE ELONGATION FACTORS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REPRODUCTION; SIGNAL TRANSDUCTION;

EID: 84919608396     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004829     Document Type: Article

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