Drosophila germ-line modulation of insulin signaling and lifespan

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 17, 2008, Pages 6368-6373

  Flatt, Thomas ^a   Min, Kyung Jin ^a,b   D'Alterio, Cecilia ^c   Villa Cuesta, Eugenia ^a   Cumbers, John ^a   Lehmann, Ruth ^d   Jones, D Leanne ^c   Tatar, Marc ^a  

^a BROWN UNIVERSITY   (United States)

^b UNIVERSITY OF ALASKA ANCHORAGE   (United States)

^c SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Aging; Endocrine regulation; Longevity; Metabolism; Reproduction

Indexed keywords

INITIATION FACTOR 4E BINDING PROTEIN; INOSINE PHOSPHATE; INSECT PROTEIN; INSULIN; INSULIN LIKE PEPTIDE; TRANSCRIPTION FACTOR FOXO; DROSOPHILA PROTEIN; MESSENGER RNA;

ARTICLE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; GENE TARGETING; HYPERINSULINISM; HYPOGLYCEMIA; LIFESPAN; LONGEVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; UPREGULATION; ANIMAL; CYTOLOGY; FEMALE; GENE; GENE EXPRESSION REGULATION; GENETICS; GERM CELL; MALE; METABOLISM; OVARY; SIGNAL TRANSDUCTION; TESTIS;

CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER;

ANIMALS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; GENE EXPRESSION REGULATION; GENES, INSECT; GERM CELLS; INSULIN; LONGEVITY; MALE; OVARY; RNA, MESSENGER; SIGNAL TRANSDUCTION; TESTIS;

EID: 44049098020     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0709128105     Document Type: Article

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