IL-6 receptor α defines effector memory CD81 T cells producing Th2 cytokines and expanding in asthma

American Journal of Respiratory and Critical Care Medicine

Volumn 190, Issue 12, 2014, Pages 1383-1394

  Lee, Naeun ^a   You, Sungyong ^b   Shin, Min Sun ^a   Lee, Won Woo ^a,c   Kang, Ki Soo ^a,d   Kim, Sang Hyun ^a,e   Kim, Wan Uk ^f   Homer, Robert J ^a   Kang, Min Jong ^a   Montgomery, Ruth R ^a   Cruz, Charles S Dela ^a   Shaw, Albert C ^a   Lee, Patty J ^a   Chupp, Geoffrey L ^a   Hwang, Daehee ^b   Kang, Insoo ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Pohang University of Science and Technology (POSTECH)   (South Korea)

^c Seoul National University College of Medicine   (South Korea)

^d Jeju National University School of Medicine   (South Korea)

^e Kangwon National University College of Medicine   (South Korea)

^f The Catholic University of Korea College of Medicine   (South Korea)

Author keywords

Asthma; CD81 T cells; Human; IL 6 receptor; Th2 cytokines

Indexed keywords

B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; GAMMA INTERFERON; GRANZYME B; INTERLEUKIN 13; INTERLEUKIN 15; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR ALPHA; INTERLEUKIN 7; INTERLEUKIN 7 RECEPTOR ALPHA; PERFORIN; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET;

ADULT; ARTICLE; ASTHMA; CD8+ T LYMPHOCYTE; CELL POPULATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; LYMPHOCYTE DIFFERENTIATION; MALE; MEMORY T LYMPHOCYTE; NATURAL KILLER CELL; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; TH2 CELL; UPREGULATION; DNA MICROARRAY; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ASTHMA; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; INTERLEUKIN-13; INTERLEUKIN-5; INTERLEUKIN-6 RECEPTOR ALPHA SUBUNIT; MALE; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84919343171     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201403-0601OC     Document Type: Article

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