IL-6 and IL-13 in induced sputum of COPD and asthma patients: Correlation with respiratory tests

Respiration

Volumn 84, Issue 2, 2012, Pages 101-107

  Grubek Jaworska, Hanna ^a   Paplińska, Magdalena ^a   Hermanowicz Salamon, Joanna ^a   Biaek Gosk, Katarzyna ^a   Dbrowska, Marta ^a   Grabczak, Elbieta ^a   Domagaa Kulawik, Joanna ^a   Stpień, Julita ^a   Chazan, Ryszrda ^a  

^a MEDICAL UNIVERSITY OF WARSAW   (Poland)

Author keywords

Asthma; Chronic obstructive pulmonary disease; Induced sputum; Interleukin 13; Interleukin 6; Respiratory disorders

Indexed keywords

INTERLEUKIN 13; INTERLEUKIN 6;

ADULT; ARTICLE; ASTHMA; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; HUMAN; LUNG FUNCTION; LUNG FUNCTION TEST; MALE; PRIORITY JOURNAL; SPUTUM LEVEL;

ADULT; AGED; ASTHMA; FEMALE; HUMANS; HYPERSENSITIVITY; INFLAMMATION; INTERLEUKIN-13; INTERLEUKIN-6; MALE; MIDDLE AGED; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY FUNCTION TESTS; SPUTUM; STATISTICS AS TOPIC;

EID: 84864871805     PISSN: 00257931     EISSN: 14230356     Source Type: Journal    
DOI: 10.1159/000334900     Document Type: Article

References (41)

1. Celli BR, MacNee W, Agusti A, Anzueto A, Berg B, Buist AS, Calverley PMA, Chavannes N, Dillard T, Fahy B, Fein A, Heffner J, Lareau S, Meek P, Martinez F, McNicholas W, Muris J, Austegard E, Pauwels R, Rennard S, Rossi A, Siafakas N, Tiep B, Vestbo J, Wouters E, ZuWallack R: Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. Eur Respir J 2004; 23: 932-946.
2. Bateman ED, Hurd SS, Barnes PJ, Bousquet J, Drazen JM, FitzGerald M, Gibson P, Ohta K, O'By rne P, Pedersen SE, Pizzichini E, Sullivan SD, Wenzel SE, Zar HJ: Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J 2008; 31: 143-178.
3. Jeffery PK: Remodeling in asthma and chronic obstructive lung disease. Am J Respir Crit Care Med 2001; 164:S28-S38.
4. Bartoli ML, Di Franco A, Vaggaggini B, Bacci E, Cianchetti S, Dente EL, Tonellib M, Paggiaro PL: Biological markers in induced sputum with phenotypes of chronic airway obstruction. Respiration 2009; 77: 265-272.
5. Vignola AM, Paganin F, Capieu L, Scichilone N, Bellia M, Maakel L, Bellia V, Godard P, Bousquet J, Chanez P: Airway remodelling assessed by sputum and high-resolution computed tomography in asthma and COPD. Eur Respir J 2004; 24:910-917.
6. Saha S, Mistry V, Siva R, Parker D, May R, Bradding P, Pavord D, Brightling CE: Induced sputum and bronchial mucosal expression of interleukin-13 is not increased in chronic obstructive pulmonary disease. Allergy 2008; 63: 1239-1243.
7. Park SW, Jangm HK, An MH, Min JW, Jang AS, Lee JH, Park CS: Interleukin-13 and in-terleukin-5 in induced sputum of eosino-philic bronchitis comparison with asthma. Chest 2005;128: 1921-1927.
8. Saha S, Doe C, Mistry V, Siddiqui S, Parker D, Sleeman M, Cohen ES, Brightling CE: Granulocyte-macrophage colony-stimulating factor expression in induced sputum and bronchial mucosa in asthma and COPD. Thorax 2009; 64:671-676.
9. van Eeden SF, Sin DD: Chronic obstructive pulmonary disease: a chronic systemic inf lammatory disease. Respiration 2008; 75: 224-238.
10. Donaldson GC, Seemungal TAR, Patel IS, Bhowmik A, Tom MA, Wilkinson TMA, Hurst JR, MacCallum PK, Wedzicha JA: Airway and systemic inflammation and decline in lung function in patients with COPD. Chest 2010; 128: 1995-2004.
11. Yende S, Waterer GW, Tolley EA, Newman AB, Bauer DC, Taaffe DR, Jensen R, Crapo R, Rubin S, Nevitt M, Simonsick EM, Satter-field S, Harris T, Kritchevsky SB: Inflammatory markers are associated with ventilatory limitation and muscle dysfunction in obstructive lung disease in well-functioning elderly subjects. Thorax 2006; 61:10-16.
12. He J-Q, Foreman MG, Shumansky K, Zhang X, Akhabir L, Sin DD, Man SFP, DeMeo DL, Litonjua AA, Silverman EK, Connett JE, An-thonisen NR, Wise RA, Paré PD, Sandford AJ: Associations of IL6 polymorphisms with lung function decline and COPD. Thorax 2009; 64:698-704.
13. Wills-Karp M, Luyimbazi J, Xu X, Schofield B, Neben TY, Karp CL, Donaldson DD: In-terleukin-13 central mediator of allergic asthma. Science 1998; 282:2258-2261.
14. Berry M.A., Parker D, Neal N, Woodman L, Morgan A, Monk P, Bradding P, Wardlaw AJ, Pavord ID, Brightling CE: Sputum and bronchial submucosal IL-13 expression in asthma and eosinophilic bronchitis. J Allergy Clin Immunol 2004; 114:1106-1109.
15. Bateman D, Hurd SS, Barnes PJ, Bousquet J, Drazen JM, FitzGera ld M, Gibson P, Ohta K, O'Byrne P, Pedersen SE, Pizzichini E, Sullivan SD, Wenzel SE, Zar HJ: Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J 2008; 31: 143-178.
16. Rabe KF, Hurd S, Anzueto A, Barnes PJ, Buist SA, Calverley P, Fukuchi Y, Jenkins C, Rodriguez-Roisin R, van Weel C, Zielinski J: Global initiative for chronic obstructive lung disease: global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease: GOLD executive summary. Am J Respir Crit Care Med 2007; 176: 532-555.
17. Standarization of Spirometry, 1994 Update. American Thoracic Society. Am J Respir Crit Care Med1995; 152:11071-11136.
18. Domagala-Kulawik J, Maskey-Warzechows-ka M, Kraszewska I, Chazan R: The cellular composition and macrophage phenotype in induced sputum in smokers and ex-smokers with COPD. Chest 2003; 123:1054-1059.
19. Chmielowicz B, Obojski A, Barczyk A, Sozanska E, Kycler Z, Demkow U, Domagała-Kulawik J; et al: Methodology of induced sputum induction and processing-recommendation of Polish Respiratory Society (in Polish). Pneumonol Alergol Pol 2008; 76: 378-394.
20. Woolhouse I, Bayley D, Stockley R: Effect of sputum processing with dithiothreitol on the detection of inflammatory mediators in chronic bronchitis and bronchiectasis. Thorax 2002; 57: 667-671.
21. Wedzicha JA, Seemungal TA, MacCallum PK, Paul EA, Donaldson GC, Bhowmik A, Jeffries DJ, Meade TW: Acute exacerbations of chronic obstructive pulmonary disease are accompanied by elevations of plasma fi-brinogen and serum IL-6 levels. Thromb Haemost 2000; 84:210-215.
22. Hacievliyagil SS, Gunen H, Mutlu LC, Kara-bulut AB, Temel I: Association between cy-tokines in induced sputum and severity of chronic obstructive pulmonary disease. Respir Med 2006; 100:846-854.
23. Attaran D, Lari SM, Towhidi M, Marallu HG, Ayatollahi H, Khajehdaluee M, Ghanei M, Basiri R: Interleukin-6 and airflow limitation in chemical warfare patients with chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis 2010; 5:335-340.
24. Bhowmik A, Seemungal TAR, Sapsford RJ, Wedzicha JA: Relation of sputum inflammatory markers to symptoms and lung function changes in COPD exacerbations. Thorax 2000; 55:114-120.
25. Barnes PJ: The cytokine network in asthma and chronic obstructive pulmonary disease. J Clin Invest 2008; 118: 3546-3556.
26. Neveu WA, Allard JL, Raymond DM, Bourassa LM, Burns SM, Bunn JY, Irvin CG, Kaminsky DA, Rincon M: Elevation of IL-6 in the allergic asthmatic airway is independent of inflammation but associates with loss of central airway function. Respir Res 2010; 11:2-10.
27. King C, Brennan S, Thompson PJ, Stewart GA: Dust mite proteolytic allergens induce cytokine release from cultured airway epithelium. J Immunol 1998; 161: 3645-3651.
28. Dixon AE, Raymond DM, Suratt BT, Bouras-sa LM, Irvin CG: Lower airway disease in asthmatics with and without rhinitis. Lung 2008; 186: 361-368.
29. Morjaria JB, Babu KS, Vijayanand P, Chau-han AJ, Davies DE, Holgate ST: Sputum IL-6 concentrations in severe asthma and its relationship with FEV1. Thorax 2011; 66: 537.
30. Lee JS, Rosengart MR, Kondragunta V, Zhang Y, McMurray J, Branch RA, Choi AMK, Sciurba FC: Inverse association of plasma IL-13 and inflammatory chemokines with lung function impairment in stable COPD: a cross-sectional cohort study. Respir Res 2007; 8:64.
31. Brightling CE, Saha S, Hollins F: Interleu-kin-13: prospects for new treatments. Clin Exp Allergy 2010; 40:42-49.
32. Miotto D, Ruggieri MP, Boschetto P, Ca-vallesco G, Papi A, Bononi I, Piola C, Murer B, Fabbri LM, Mapp CE: Interleukin-13 and-4 expression in the central airways of smokers with chronic bronchitis. Eur Respir J 2003; 22:602-608.
33. Yamada H, Yamaguchi M, Yamamoto K, Nakajima T, Hirai K, Morita Y, Sano Y, Yamada H: Eotaxin in induced sputum of asthmatics: relationship with eosinophils and eosinophil cationic protein in sputum. Allergy 2000; 55: 392-397.
34. Pope SM, Brandt EB, Mishra A, Hogan SP, Zimmermann NKI, Foster PS, Rothenberg ME: IL-13 induces eosinophil recruitment into the lung by an IL-5-and eotaxin-depen-dent mechanism. J Allergy Clin Immunol 2001; 108: 594-601.
35. Matsukura S, Stellato C, Georas SN, Caso-laro V, Plitt JR, Miura K, Kurosawa S, Schindler U, Schleimer RP: Interleukin-13 upregulates eotaxin expression in airway epithelial cells by a STAT6-dependent mechanism. Am J Respir Cell Mol Biol 2001; 24: 755-761.
36. Pope SM, Fulkerson PC, Blanchard C, Akei HS, Nikolaidis NM, Zimmermann N, Molkentin JD, Rothenberg ME: Identification of a cooperative mechanism involving interleukin-13 and eotaxin-2 in experimental allergic lung inflammation. J Biol Chem 2005; 80:13952-13961.
37. Yang M, Hogan SP, Mahalingam S, Pope SM, Zimmermann N, Fulkerson P, Dent LA, Young IG, Matthaei KI, Rothenberg ME, Foster PS: Eotaxin-2 and IL-5 cooperate in the lung to regulate IL-13 production and airway eosinophilia and hyperreactivity. J Allergy Clin Immunol 2003; 112: 935-943.
38. Bocchino V, Bertorelli G, Bertrand CP, Po-nath PD, Newman W, Franco C, Marruchel-la A, Merlini S, Del Donno M, Zhuo X, Oli-vieri D: Eotaxin and CCR3 are up-regulated in exacerbations of chronic bronchitis. Al-lerg y 2002; 57: 17-22.
39. Honda R, Ichiyama T, Sunagawa S, Maeba S, Hasegawa K, Furukawa S: Inhaled cortico-steroid therapy reduces cytokine levels in sputum from very preterm infants with chronic lung disease. Acta Paediatr 2009; 104:118-122.
40. Kai S, Nomura A, Morishima Y, Ishii Y, Sakamoto T, Kiwamoto T, Iizuka T, Sekizawa K: Effect of inhaled steroids on increased collagen synthesis in asthma. Respiration 2007; 74:154-158.
41. Dente FL, Bacci E, Bartoli ML, Cianchetti S, Costa F, Di Franco A, Malagrinò L, Vagag-gini B, Pa g g iaro P: Effects of ora l pred nisone on sputum eosinophils and cytokines in patients with severe refractory asthma. Ann Allerg Asthma Immunol 2010; 104:464-470.