Celastrol, an oral heat shock activator, ameliorates multiple animal disease models of cell death

Cell Stress and Chaperones

Volumn 20, Issue 1, 2015, Pages 185-201

  Sharma, Sudhish ^a   Mishra, Rachana ^a   Walker, Brandon L ^a   Deshmukh, Savitha ^a   Zampino, Manuela ^a   Patel, Jay ^a   Anamalai, Mani ^a   Simpson, David ^a   Singh, Ishwar S ^a   Kaushal, Shalesh ^b   Kaushal, Sunjay ^a  

^a UNIVERSITY OF MARYLAND MEDICAL CENTER   (United States)

^b Retina Specialty Institute   (United States)

Author keywords

Cardiomyopathy; Celastrol; Heat shock response; HSPs; Myocardial infarct

Indexed keywords

ANIMALIA;

DNA BINDING PROTEIN; DOXORUBICIN; GATA4 PROTEIN, MOUSE; HEAT SHOCK PROTEIN; HSF1 PROTEIN, MOUSE; INTERLEUKIN 1BETA; INTERLEUKIN 6; THIOACETAMIDE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 4; TRIPTERINE; TRITERPENE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ANTAGONISTS AND INHIBITORS; APOPTOSIS; C57BL MOUSE; CARDIOMYOPATHY; CELL SURVIVAL; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION; GENETICS; HEART INFARCTION; HUMAN; LIVER; LIVER FAILURE; MALE; METABOLISM; MOUSE; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; CARDIOMYOPATHIES; CELL LINE, TUMOR; CELL SURVIVAL; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; DOXORUBICIN; GATA4 TRANSCRIPTION FACTOR; GENE EXPRESSION; HEAT-SHOCK PROTEINS; HUMANS; INTERLEUKIN-1BETA; INTERLEUKIN-6; LIVER; LIVER FAILURE; MALE; MICE; MICE, INBRED C57BL; MYOCARDIAL INFARCTION; THIOACETAMIDE; TRANSCRIPTION FACTORS; TRITERPENES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84914670576     PISSN: 13558145     EISSN: 14661268     Source Type: Journal    
DOI: 10.1007/s12192-014-0536-1     Document Type: Article

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