Celastrol, an NF-κB Inhibitor, Improves Insulin Resistance and Attenuates Renal Injury in db/db Mice

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Kim, Jung Eun ^a   Lee, Mi Hwa ^a   Nam, Deok Hwa ^a   Song, Hye Kyoung ^a   Kang, Young Sun ^a   Lee, Ji Eun ^b   Kim, Hyun Wook ^b   Cha, Jin Joo ^a   Hyun, Young Youl ^c   Han, Sang Youb ^d   Han, Kum Hyun ^d   Han, Jee Young ^e   Cha, Dae Ryong ^a  

^a Korea University   (South Korea)

^b Wonkwang University   (South Korea)

^c Sungkyunkwan University   (South Korea)

^d Inje University   (South Korea)

^e Inha University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; ALBUMIN; CELASTROL; COLLAGEN TYPE 4; CREATININE; GLUCOSE; HEMOGLOBIN A1C; PLASMINOGEN ACTIVATOR INHIBITOR 1; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL EXPANSION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIABETIC NEPHROPATHY; DRUG EFFECT; DRUG MECHANISM; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; INSULIN RESISTANCE; KIDNEY FUNCTION; KIDNEY INJURY; KIDNEY STRUCTURE; LIPID METABOLISM; LIPID STORAGE; MALE; MESANGIUM CELL; MOUSE; NONHUMAN; OBESITY; OXIDATIVE STRESS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; TREATMENT DURATION;

ADIPOSE TISSUE; ALBUMINURIA; ANIMALS; CELLS, CULTURED; CYTOKINES; DIABETES MELLITUS, EXPERIMENTAL; FATTY ACIDS; HEMOGLOBIN A, GLYCOSYLATED; INFLAMMATION MEDIATORS; INSULIN RESISTANCE; KIDNEY; KIDNEY FUNCTION TESTS; KIDNEY GLOMERULUS; LIPID PEROXIDATION; LIPIDS; LIVER; MALE; MICE; NF-KAPPA B; OXIDATIVE STRESS; PODOCYTES; TRITERPENES;

ANIMALIA; MUS;

EID: 84876817513     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0062068     Document Type: Article

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