Celastrol ameliorates HIV-1 Tat-induced inflammatory responses via NF-kappaB and AP-1 inhibition and heme oxygenase-1 induction in astrocytes

Toxicology and Applied Pharmacology

Volumn 280, Issue 1, 2014, Pages 42-52

  Youn, Gi Soo ^a   Kwon, Dong Joo ^a,d   Ju, Sung Mi ^a   Rhim, Hyangshuk ^b   Bae, Yong Soo ^c   Choi, Soo Young ^a   Park, Jinseu ^a  

^a Hallym University   (South Korea)

^b The Catholic University of Korea   (South Korea)

^c Sungkyunkwan University   (South Korea)

^d Hongcheon Institute of Medicinal Herb   (South Korea)

Author keywords

AP 1; Astrocyte; HO 1; Inflammation; NF B; Tat

Indexed keywords

CELASTROL; GAMMA INTERFERON INDUCIBLE PROTEIN 10; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 8; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; SMALL INTERFERING RNA; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NRF2; VASCULAR CELL ADHESION MOLECULE 1; ANTIINFLAMMATORY AGENT; TRIPTERINE; TRITERPENE;

ARTICLE; ASTROCYTE; ASTROCYTOMA CELL; CELL ADHESION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME INDUCTION; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MONOCYTE; NERVOUS SYSTEM INFLAMMATION; PROTEIN EXPRESSION; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL LINE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; PHYSIOLOGY;

ANTI-INFLAMMATORY AGENTS; ASTROCYTES; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INDUCTION; HEME OXYGENASE-1; HUMANS; NF-KAPPA B; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; TRANSCRIPTION FACTOR AP-1; TRITERPENES;

EID: 84906250310     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2014.07.010     Document Type: Article

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