Protective effect of celastrol in rat cerebral ischemia model: Down-regulating p-JNK, p-c-Jun and NF-κB

Brain Research

Volumn 1464, Issue , 2012, Pages 8-13

  Li, Yanhua ^a   He, Dan ^a   Zhang, Xiangjian ^a,b,c   Liu, Zongjie ^a   Zhang, Xiaolin ^a   Dong, Lipeng ^a   Xing, Yinxue ^a   Wang, Chaohui ^a   Qiao, Huimin ^a   Zhu, Chunhua ^a   Chen, Yulin ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b Hebei Institute of Cardio Cerebral Vascular Diseases   (China)

^c Hebei Key Laboratory for Neurology   (China)

Author keywords

Celastrol; Cerebral ischemia; Nuclear factor kappa B; Phospho c Jun; Phospho JNK; Protective effect

Indexed keywords

CELASTROL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN C JUN; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN PROTECTION; BRAIN WATER; CONTROLLED STUDY; DOWN REGULATION; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STROKE;

ANIMALS; BRAIN; BRAIN ISCHEMIA; DOWN-REGULATION; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; NEUROPROTECTIVE AGENTS; NF-KAPPA B; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-JUN; RATS; RATS, SPRAGUE-DAWLEY; TRITERPENES;

RATTUS;

EID: 84862021422     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.04.054     Document Type: Article

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