Celastrol inhibits pro-inflammatory cytokine secretion in Crohn's disease biopsies

Biochemical and Biophysical Research Communications

Volumn 322, Issue 3, 2004, Pages 778-786

  Pinna, Guillaume F ^a   Fiorucci, Marc ^a   Reimund, Jean Marie ^a,b,c   Taquet, Nathalie ^a   Arondel, Yves ^b   Muller, Christian D ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b UNIVERSITY HOSPITAL OF STRASBOURG   (France)

^c INSERM   (France)

Author keywords

Anti inflammatory agents; Cytokines; Human; Immunosuppressive agents; Inflammation mediators; Signal transduction

Indexed keywords

ANTIINFLAMMATORY AGENT; CELASTROL; CYTOKINE; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; TRITERPENE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CROHN DISEASE; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG EFFECT; DRUG MECHANISM; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IC 50; IMMUNOHISTOCHEMISTRY; MONOCYTE; MUCOSA INFLAMMATION; PRIORITY JOURNAL; PROTEIN TRANSPORT;

CELL LINE; CELL SURVIVAL; CELLS, CULTURED; COLON; CROHN DISEASE; CYTOKINES; HUMANS; INFLAMMATION; LIPOPOLYSACCHARIDES; MONOCYTES; RECEPTORS, GLUCOCORTICOID; TRITERPENES;

EID: 4444238155     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.07.186     Document Type: Article

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