Suppression of autoimmune arthritis by Celastrus-derived Celastrol through modulation of pro-inflammatory chemokines

Bioorganic and Medicinal Chemistry

Volumn 20, Issue 17, 2012, Pages 5229-5234

  Venkatesha, Shivaprasad H ^a   Astry, Brian ^a   Nanjundaiah, Siddaraju M ^a   Yu, Hua ^a   Moudgil, Kamal D ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Animal model; Arthritis; Chemokines; Cytokines; Inflammation; Natural plant products; Traditional Chinese medicine

Indexed keywords

CELASTROL; CHEMOKINE; CHEMOKINE RECEPTOR CCR1; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MELANOMA GROWTH STIMULATORY ACTIVITY FACTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; TUMOR NECROSIS FACTOR ALPHA;

ADJUVANT ARTHRITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELASTRUS; CELASTRUS SCANDENS; CELL ADHESION; CELL INFILTRATION; CELL MIGRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; DOWN REGULATION; DRUG MECHANISM; DRUG SCREENING; IMMUNOMODULATION; IN VITRO STUDY; LYMPH NODE CELL; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; RHEUMATOID ARTHRITIS; SPLEEN CELL; UPREGULATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ARTHRITIS, RHEUMATOID; CELASTRUS; CELL MOVEMENT; CHEMOKINES; CYTOKINES; DISEASE MODELS, ANIMAL; FLOW CYTOMETRY; MALE; RATS; RATS, INBRED LEW; RECEPTORS, CHEMOKINE; SPLEEN; TRITERPENES;

ANIMALIA; CELASTRUS; RATTUS;

EID: 84865042616     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2012.06.050     Document Type: Article

References (49)

1. Lipsky, P. E. In Harrison's Principles of Internal Medicine; A. Fauci, E. Braunwald, D. Kasper, S. Hauser, D. longo, J. Jameson and J. Loscalzo, Ed.; McGraw Hill New York, NY, USA New York, 2008; Vol. 2, Part 14, Chapter 314, pp. 2083.
2. Z. Szekanecz, J. Kim, and A.E. Koch Semin. Immunol. 15 2003 15
3. T.A. Springer Annu. Rev. Physiol. 57 1995 827
4. A. Zlotnik, and O. Yoshie Immunity 12 2000 121
5. P.M. Murphy, M. Baggiolini, I.F. Charo, C.A. Hebert, R. Horuk, K. Matsushima, L.H. Miller, J.J. Oppenheim, and C.A. Power Pharmacol. Rev. 52 2000 145
6. J. Stanczyk, M.L. Kowalski, J. Grzegorczyk, B. Szkudlinska, M. Jarzebska, M. Marciniak, and M. Synder Mediators Inflamm. 2005 2005 343
7. S.H. Venkatesha, B.M. Berman, and K.D. Moudgil Bioorg. Med. Chem. 19 2011 21
8. S.M. Nanjundaiah, D.Y. Lee, Z. Ma, H.H. Fong, L. Lao, B.M. Berman, and K.D. Moudgil Evid Based Complement Alternat Med 2012 2012 589256
9. D. Su, and L. Li J. Health Care Poor Underserved 22 2011 296
10. C.H. Wu, C.C. Wang, and J. Kennedy Clin. Ther. 33 2011 1749
11. L. Tong, and K.D. Moudgil Arthritis Res. Ther. 9 2007 R70
12. S.H. Venkatesha, H. Yu, R. Rajaiah, L. Tong, and K.D. Moudgil J. Biol. Chem. 286 2011 15138
13. Cascao, R.; Vidal, B.; Raquel, H.; Neves-Costa, A.; Figueiredo, N.; Gupta, V.; Fonseca, J. E.; Moita, L. F. Autoimmunity reviews, 2012.
14. T. Zhang, Y. Li, Y. Yu, P. Zou, Y. Jiang, and D. Sun J. Biol. Chem. 284 2009 35381
15. L. Klaic, R.I. Morimoto, and R.B. Silverman ACS Chem. Biol. 7 2012 928
16. A. Chadli, S.J. Felts, Q. Wang, W.P. Sullivan, M.V. Botuyan, A. Fauq, M. Ramirez-Alvarado, and G. Mer J. Biol. Chem. 285 2010 4224
17. C.M. Pearson Proc. Soc. Exp. Biol. Med. 91 1956 95
18. K.D. Moudgil, T.T. Chang, H. Eradat, A.M. Chen, R.S. Gupta, E. Brahn, and E.E. Sercarz J. Exp. Med. 185 1997 1307
19. R. Rajaiah, M. Puttabyatappa, S.K. Polumuri, and K.D. Moudgil J. Biol. Chem. 286 2011 2817
20. K. Ebnet, E.P. Kaldjian, A.O. Anderson, and S. Shaw Annu. Rev. Immunol. 14 1996 155
21. A.C. Issekutz, and T.B. Issekutz J. Immunol. 2002 1934 168
22. F.W. Luscinskas, S. Ma, A. Nusrat, C.A. Parkos, and S.K. Shaw Semin. Immunol. 14 2002 105
23. L. Boiardi, P. Macchioni, R. Meliconi, L. Pulsatelli, A. Facchini, and C. Salvarani Clin. Exp. Rheumatol. 17 1999 419
24. S. Shahrara, S.R. Pickens, A.M. Mandelin 2nd, W.J. Karpus, Q. Huang, J.K. Kolls, and R.M. Pope J. Immunol. 184 2010 4479
25. A.E. Koch, S.L. Kunkel, M.R. Shah, S. Hosaka, M.M. Halloran, G.K. Haines, M.D. Burdick, R.M. Pope, and R.M. Strieter J. Immunol. 155 1995 3660
26. D.A. Barnes, J. Tse, M. Kaufhold, M. Owen, J. Hesselgesser, R. Strieter, R. Horuk, and H.D. Perez J. Clin. Investig. 101 1998 2910
27. X. Chen, J.J. Oppenheim, and O.M. Howard Cell. Mol. Immunol. 1 2004 336
28. M.M. Halloran, J.M. Woods, R.M. Strieter, Z. Szekanecz, M.V. Volin, S. Hosaka, G.K. Haines 3rd, S.L. Kunkel, M.D. Burdick, A. Walz, and A.E. Koch J. Immunol. 162 1999 7492
29. H. Okamoto, and N. Kamatani Rheumatology (Oxford England) 45 2006 230
30. J.J. Haringman, R.L. Oostendorp, and P.P. Tak Expert opinion on emerging drugs 10 2005 299
31. C.S. Haas, R.J. Martinez, N. Attia, G.K. Haines 3rd, P.L. Campbell, and A.E. Koch Arthritis Rheum. 52 2005 3718
32. J.H. Ruth, C.S. Haas, C.C. Park, M.A. Amin, R.J. Martinez, G.K. Haines 3rd, S. Shahrara, P.L. Campbell, and A.E. Koch Arthritis Rheum. 54 2006 765
33. J.H. Ruth, M.V. Volin, G.K. Haines 3rd, D.C. Woodruff, K.J. Katschke Jr., J.M. Woods, C.C. Park, J.C. Morel, and A.E. Koch Arthritis Rheum. 44 2001 1568
34. Y. Hatano, T. Kasama, H. Iwabuchi, R. Hanaoka, H.T. Takeuchi, L. Jing, Y. Mori, K. Kobayashi, M. Negishi, H. Ide, and M. Adachi Ann. Rheum. Dis. 58 1999 297
35. H. Ogata, M. Takeya, T. Yoshimura, K. Takagi, and K. Takahashi J. Pathol. 182 1997 106
36. S. Thornton, L.E. Duwel, G.P. Boivin, Y. Ma, and R. Hirsch Arthritis Rheum. 42 1999 1109
37. D.J. Schrier, R.C. Schimmer, C.M. Flory, D.K. Tung, and P.A. Ward J. Leukoc. Biol. 63 1998 359
38. P.R. Pine, B. Chang, N. Schoettler, M.L. Banquerigo, S. Wang, A. Lau, F. Zhao, E.B. Grossbard, D.G. Payan, and E. Brahn Clin. Immunol. (Orlando Fla) 124 2007 244
39. T. Nanki, T. Shimaoka, K. Hayashida, K. Taniguchi, S. Yonehara, and N. Miyasaka Arthritis Rheum. 52 2005 3004
40. I. Salomon, N. Netzer, G. Wildbaum, S. Schif-Zuck, G. Maor, and N. Karin J. Immunol. 169 2002 2685
41. A. Guglielmotti, E. D'Onofrio, I. Coletta, L. Aquilini, C. Milanese, and M. Pinza Inflamm. Res. 51 2002 252
42. T. Kasama, R.M. Strieter, N.W. Lukacs, P.M. Lincoln, M.D. Burdick, and S.L. Kunkel J. Clin. Investig. 95 1995 2868
43. C.M. Brodmerkel, R. Huber, M. Covington, S. Diamond, L. Hall, R. Collins, L. Leffet, K. Gallagher, P. Feldman, P. Collier, M. Stow, X. Gu, F. Baribaud, N. Shin, B. Thomas, T. Burn, G. Hollis, S. Yeleswaram, K. Solomon, S. Friedman, A. Wang, C.B. Xue, R.C. Newton, P. Scherle, and K. Vaddi J. Immunol. 175 2005 5370
44. Y. Jin, X. Cui, U.P. Singh, A.A. Chumanevich, B. Harmon, P. Cavicchia, A.B. Hofseth, V. Kotakadi, B. Stroud, S.R. Volate, T.G. Hurley, J.R. Hebert, and L.J. Hofseth Mol. Nutr. Food Res. 54 2010 1506
45. H. Marotte, J.H. Ruth, P.L. Campbell, A.E. Koch, and S. Ahmed Rheumatology (Oxford England) 49 2010 467
46. T.M. Haqqi, D.D. Anthony, S. Gupta, N. Ahmad, M.S. Lee, G.K. Kumar, and H. Mukhtar Proc. Natl. Acad. Sci. U S A 96 1999 4524
47. Y. Shen, and J.D. Lu Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 7 2009 157
48. S. Shahrara, M.A. Amin, J.M. Woods, G.K. Haines, and A.E. Koch Arthritis Rheum. 48 2003 3568
49. A.E. Cardona, M.E. Sasse, L. Liu, S.M. Cardona, M. Mizutani, C. Savarin, T. Hu, and R.M. Ransohoff Blood 112 2008 256