-
1
-
-
57049186623
-
How to live long and prosper: Autophagy, mitochondria, and aging
-
PMID:18927201
-
Yen WL, Klionsky DJ. How to live long and prosper: autophagy, mitochondria, and aging. Physiology (Bethesda) 2008; 23:248-62; PMID:18927201; http://dx.doi.org/10.1152/physiol.00013.2008
-
(2008)
Physiology (Bethesda)
, vol.23
, pp. 248-262
-
-
Yen, W.L.1
Klionsky, D.J.2
-
2
-
-
79955631150
-
Autophagy in the cellular energetic balance
-
PMID:21531332
-
Singh R, Cuervo AM. Autophagy in the cellular energetic balance. Cell Metab 2011; 13:495-504; PMID:21531332; http://dx.doi.org/10.1016/j. cmet.2011.04.004
-
(2011)
Cell Metab
, vol.13
, pp. 495-504
-
-
Singh, R.1
Cuervo, A.M.2
-
3
-
-
78751672975
-
Autophagy in immunity and inflammation
-
PMID:21248839
-
Levine B, Mizushima N, Virgin HW. Autophagy in immunity and inflammation. Nature 2011; 469:323-35; PMID:21248839; http://dx.doi.org/10.1038/nature09782
-
(2011)
Nature
, vol.469
, pp. 323-335
-
-
Levine, B.1
Mizushima, N.2
Virgin, H.W.3
-
4
-
-
33646800306
-
Loss of autophagy in the central nervous system causes neurodegeneration in mice
-
PMID:16625205
-
Komatsu M, Waguri S, Chiba T, Murata S, Iwata J, Tanida I, et al. Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature 2006; 441:880-4; PMID:16625205; http://dx.doi.org/10.1038/nature04723
-
(2006)
Nature
, vol.441
, pp. 880-884
-
-
Komatsu, M.1
Waguri, S.2
Chiba, T.3
Murata, S.4
Iwata, J.5
Tanida, I.6
-
5
-
-
0345166111
-
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
-
PMID:14657337
-
Yue Z, Jin S, Yang C, Levine AJ, Heintz N. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci U S A 2003; 100:15077-82; PMID:14657337; http://dx.doi.org/10.1073/pnas.2436255100
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 15077-15082
-
-
Yue, Z.1
Jin, S.2
Yang, C.3
Levine, A.J.4
Heintz, N.5
-
6
-
-
70449927247
-
Autophagy is required to maintain muscle mass
-
PMID:19945408
-
Masiero E, Agatea L, Mammucari C, Blaauw B, Loro E, Komatsu M, et al. Autophagy is required to maintain muscle mass. Cell Metab 2009; 10:507-15; PMID:19945408; http://dx.doi.org/10.1016/j. cmet.2009.10.008
-
(2009)
Cell Metab
, vol.10
, pp. 507-515
-
-
Masiero, E.1
Agatea, L.2
Mammucari, C.3
Blaauw, B.4
Loro, E.5
Komatsu, M.6
-
7
-
-
34249714158
-
The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress
-
PMID:17450150
-
Nakai A, Yamaguchi O, Takeda T, Higuchi Y, Hikoso S, Taniike M, et al. The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress. Nat Med 2007; 13:619-24; PMID:17450150; http://dx.doi.org/ 10.1038/nm1574
-
(2007)
Nat Med
, vol.13
, pp. 619-624
-
-
Nakai, A.1
Yamaguchi, O.2
Takeda, T.3
Higuchi, Y.4
Hikoso, S.5
Taniike, M.6
-
8
-
-
65949095803
-
Autophagy regulates lipid metabolism
-
PMID:19339967
-
Singh R, Kaushik S, Wang Y, Xiang Y, Novak I, Komatsu M, et al. Autophagy regulates lipid metabolism. Nature 2009; 458:1131-5; PMID:19339967; http://dx.doi.org/10.1038/nature07976
-
(2009)
Nature
, vol.458
, pp. 1131-1135
-
-
Singh, R.1
Kaushik, S.2
Wang, Y.3
Xiang, Y.4
Novak, I.5
Komatsu, M.6
-
9
-
-
36849088609
-
Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila
-
PMID:18083103
-
Berry DL, Baehrecke EH. Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila. Cell 2007; 131:1137-48; PMID:18083103; http://dx.doi.org/10.1016/j. cell.2007.10.048
-
(2007)
Cell
, vol.131
, pp. 1137-1148
-
-
Berry, D.L.1
Baehrecke, E.H.2
-
10
-
-
47849094901
-
Autophagic control of listeria through intracellular innate immune recognition in drosophila
-
PMID:18604211
-
Yano T, Mita S, Ohmori H, Oshima Y, Fujimoto Y, Ueda R, et al. Autophagic control of listeria through intracellular innate immune recognition in drosophila. Nat Immunol 2008; 9:908-16; PMID:18604211; http://dx.doi.org/10. 1038/ni.1634
-
(2008)
Nat Immunol
, vol.9
, pp. 908-916
-
-
Yano, T.1
Mita, S.2
Ohmori, H.3
Oshima, Y.4
Fujimoto, Y.5
Ueda, R.6
-
11
-
-
36849021043
-
Atg7- dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila
-
PMID:18056421
-
Juhász G, Erdi B, Sass M, Neufeld TP. Atg7- dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila. Genes Dev 2007; 21:3061-6; PMID:18056421; http://dx.doi. org/10.1101/gad.1600707
-
(2007)
Genes Dev
, vol.21
, pp. 3061-3066
-
-
Juhász, G.1
Erdi, B.2
Sass, M.3
Neufeld, T.P.4
-
13
-
-
70350449062
-
MTORC1 phosphorylates the ULK1- mAtg13-FIP200 autophagy regulatory complex
-
PMID:19690328
-
Chan EY. mTORC1 phosphorylates the ULK1- mAtg13-FIP200 autophagy regulatory complex. Sci Signal 2009; 2:pe51; PMID:19690328; http://dx.doi.org/ 10.1126/scisignal.284pe51
-
(2009)
Sci Signal
, vol.2
-
-
Chan, E.Y.1
-
14
-
-
79251587803
-
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy
-
PMID:21205641
-
Egan DF, Shackelford DB, Mihaylova MM, Gelino S, Kohnz RA, Mair W, et al. Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy. Science 2011; 331:456-61; PMID:21205641; http://dx.doi.org/10.1126/science.1196371
-
(2011)
Science
, vol.331
, pp. 456-461
-
-
Egan, D.F.1
Shackelford, D.B.2
Mihaylova, M.M.3
Gelino, S.4
Kohnz, R.A.5
Mair, W.6
-
15
-
-
79551598347
-
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
-
PMID:21258367
-
Kim J, Kundu M, Viollet B, Guan KL. AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat Cell Biol 2011; 13:132-41; PMID:21258367; http://dx.doi.org/10.1038/ncb2152
-
(2011)
Nat Cell Biol
, vol.13
, pp. 132-141
-
-
Kim, J.1
Kundu, M.2
Viollet, B.3
Guan, K.L.4
-
16
-
-
77957728513
-
The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy
-
PMID:20921139
-
Di Bartolomeo S, Corazzari M, Nazio F, Oliverio S, Lisi G, Antonioli M, et al. The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy. J Cell Biol 2010; 191:155-68; PMID:20921139; http://dx.doi.org/10.1083/jcb.201002100
-
(2010)
J Cell Biol
, vol.191
, pp. 155-168
-
-
Di Bartolomeo, S.1
Corazzari, M.2
Nazio, F.3
Oliverio, S.4
Lisi, G.5
Antonioli, M.6
-
17
-
-
34848886914
-
Autophagosome formation: Core machinery and adaptations
-
PMID:17909521
-
Xie Z, Klionsky DJ. Autophagosome formation: core machinery and adaptations. Nat Cell Biol 2007; 9:1102-9; PMID:17909521; http://dx.doi. org/10.1038/ncb1007-1102
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1102-1109
-
-
Xie, Z.1
Klionsky, D.J.2
-
18
-
-
80053430528
-
ULK1 inhibits the kinase activity of mTORC1 and cell proliferation
-
PMID:21795849
-
Jung CH, Seo M, Otto NM, Kim DH. ULK1 inhibits the kinase activity of mTORC1 and cell proliferation. Autophagy 2011; 7:1212-21; PMID:21795849; http://dx.doi.org/10.4161/auto.7.10.16660
-
(2011)
Autophagy
, vol.7
, pp. 1212-1221
-
-
Jung, C.H.1
Seo, M.2
Otto, N.M.3
Kim, D.H.4
-
19
-
-
79960014848
-
ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding
-
PMID:21460630
-
Dunlop EA, Hunt DK, Acosta-Jaquez HA, Fingar DC, Tee AR. ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding. Autophagy 2011; 7:737-47; PMID:21460630; http://dx.doi.org/ 10.4161/auto.7.7.15491
-
(2011)
Autophagy
, vol.7
, pp. 737-747
-
-
Dunlop, E.A.1
Hunt, D.K.2
Acosta-Jaquez, H.A.3
Fingar, D.C.4
Tee, A.R.5
-
20
-
-
33845874899
-
Direct induction of autophagy by Atg1 inhibits cell growth and induces apoptotic cell death
-
PMID:17208179
-
Scott RC, Juhász G, Neufeld TP. Direct induction of autophagy by Atg1 inhibits cell growth and induces apoptotic cell death. Curr Biol 2007; 17:1-11; PMID:17208179; http://dx.doi.org/10.1016/j. cub.2006.10.053
-
(2007)
Curr Biol
, vol.17
, pp. 1-11
-
-
Scott, R.C.1
Juhász, G.2
Neufeld, T.P.3
-
21
-
-
34047154536
-
ATG1, an autophagy regulator, inhibits cell growth by negatively regulating S6 kinase
-
PMID:17347671
-
Lee SB, Kim S, Lee J, Park J, Lee G, Kim Y, et al. ATG1, an autophagy regulator, inhibits cell growth by negatively regulating S6 kinase. EMBO Rep 2007; 8:360-5; PMID:17347671; http://dx.doi. org/10.1038/sj.embor.7400917
-
(2007)
EMBO Rep
, vol.8
, pp. 360-365
-
-
Lee, S.B.1
Kim, S.2
Lee, J.3
Park, J.4
Lee, G.5
Kim, Y.6
-
22
-
-
79955941230
-
Unc-51/ATG1 controls axonal and dendritic development via kinesinmediated vesicle transport in the Drosophila brain
-
PMID:21589871
-
Mochizuki H, Toda H, Ando M, Kurusu M, Tomoda T, Furukubo-Tokunaga K. Unc-51/ATG1 controls axonal and dendritic development via kinesinmediated vesicle transport in the Drosophila brain. PLoS One 2011; 6:e19632; PMID:21589871; http://dx.doi.org/10.1371/journal.pone.0019632
-
(2011)
PLoS One
, vol.6
-
-
Mochizuki, H.1
Toda, H.2
Ando, M.3
Kurusu, M.4
Tomoda, T.5
Furukubo-Tokunaga, K.6
-
23
-
-
57749095080
-
UNC-51/ATG1 kinase regulates axonal transport by mediating motor-cargo assembly
-
PMID:19056884
-
rd, Josowitz R, Krasieva TB, Lamorte VJ, et al. UNC-51/ATG1 kinase regulates axonal transport by mediating motor-cargo assembly. Genes Dev 2008; 22:3292-307; PMID:19056884; http://dx.doi.org/10.1101/gad.1734608
-
(2008)
Genes Dev
, vol.22
, pp. 3292-3307
-
-
Toda, H.1
Mochizuki, H.2
Flores III, R.3
Josowitz, R.4
Krasieva, T.B.5
Lamorte, V.J.6
-
24
-
-
67651096073
-
Molecular characterization of Pegarn: A Drosophila homolog of UNC-51 kinase
-
PMID:18636236
-
Ahantarig A, Chadwell LV, Terrazas IB, Garcia CT, Nazarian JJ, Lee HK, et al. Molecular characterization of Pegarn: a Drosophila homolog of UNC-51 kinase. Mol Biol Rep 2009; 36:1311-21; PMID:18636236; http://dx.doi.org/10.1007/ s11033-008-9314-4
-
(2009)
Mol Biol Rep
, vol.36
, pp. 1311-1321
-
-
Ahantarig, A.1
Chadwell, L.V.2
Terrazas, I.B.3
Garcia, C.T.4
Nazarian, J.J.5
Lee, H.K.6
-
25
-
-
34250728186
-
Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles
-
PMID:17435236
-
Simonsen A, Cumming RC, Lindmo K, Galaviz V, Cheng S, Rusten TE, et al. Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles. Genetics 2007; 176:1283-97; PMID:17435236; http://dx.doi. org/10.1534/genetics. 106.065011
-
(2007)
Genetics
, vol.176
, pp. 1283-1297
-
-
Simonsen, A.1
Cumming, R.C.2
Lindmo, K.3
Galaviz, V.4
Cheng, S.5
Rusten, T.E.6
-
26
-
-
0033377776
-
A mouse serine/threonine kinase homologous to C. Elegans UNC51 functions in parallel fiber formation of cerebellar granule neurons
-
PMID:10624947
-
Tomoda T, Bhatt RS, Kuroyanagi H, Shirasawa T, Hatten ME. A mouse serine/threonine kinase homologous to C. elegans UNC51 functions in parallel fiber formation of cerebellar granule neurons. Neuron 1999; 24:833-46; PMID:10624947; http://dx.doi.org/10.1016/S0896-6273(00)81031-4
-
(1999)
Neuron
, vol.24
, pp. 833-846
-
-
Tomoda, T.1
Bhatt, R.S.2
Kuroyanagi, H.3
Shirasawa, T.4
Hatten, M.E.5
-
27
-
-
1642417689
-
Role of Unc51.1 and its binding partners in CNS axon outgrowth
-
PMID:15014045
-
Tomoda T, Kim JH, Zhan C, Hatten ME. Role of Unc51.1 and its binding partners in CNS axon outgrowth. Genes Dev 2004; 18:541-58; PMID:15014045; http://dx.doi.org/10.1101/gad.1151204
-
(2004)
Genes Dev
, vol.18
, pp. 541-558
-
-
Tomoda, T.1
Kim, J.H.2
Zhan, C.3
Hatten, M.E.4
-
28
-
-
80655144736
-
Binding to syntenin-1 protein defines a new mode of ubiquitin-based interactions regulated by phosphorylation
-
PMID:21949238
-
Rajesh S, Bago R, Odintsova E, Muratov G, Baldwin G, Sridhar P, et al. Binding to syntenin-1 protein defines a new mode of ubiquitin-based interactions regulated by phosphorylation. J Biol Chem 2011; 286:39606-14; PMID:21949238; http://dx.doi. org/10.1074/jbc.M111.262402
-
(2011)
J Biol Chem
, vol.286
, pp. 39606-39614
-
-
Rajesh, S.1
Bago, R.2
Odintsova, E.3
Muratov, G.4
Baldwin, G.5
Sridhar, P.6
-
29
-
-
34347236186
-
Unc-51-like kinase 1/2-mediated endocytic processes regulate filopodia extension and branching of sensory axons
-
PMID:17389358
-
Zhou X, Babu JR, da Silva S, Shu Q, Graef IA, Oliver T, et al. Unc-51-like kinase 1/2-mediated endocytic processes regulate filopodia extension and branching of sensory axons. Proc Natl Acad Sci U S A 2007; 104:5842-7; PMID:17389358; http://dx.doi. org/10.1073/pnas.0701402104
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 5842-5847
-
-
Zhou, X.1
Babu, J.R.2
Da Silva, S.3
Shu, Q.4
Graef, I.A.5
Oliver, T.6
-
30
-
-
43149090064
-
FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells
-
PMID:18443221
-
Hara T, Takamura A, Kishi C, Iemura S, Natsume T, Guan JL, et al. FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells. J Cell Biol 2008; 181:497-510; PMID:18443221; http://dx.doi.org/10.1083/ jcb.200712064
-
(2008)
J Cell Biol
, vol.181
, pp. 497-510
-
-
Hara, T.1
Takamura, A.2
Kishi, C.3
Iemura, S.4
Natsume, T.5
Guan, J.L.6
-
31
-
-
0034678330
-
Suppression of Pyk2 kinase and cellular activities by FIP200
-
PMID:10769033
-
Ueda H, Abbi S, Zheng C, Guan JL. Suppression of Pyk2 kinase and cellular activities by FIP200. J Cell Biol 2000; 149:423-30; PMID:10769033; http://dx.doi.org/10.1083/jcb.149.2.423
-
(2000)
J Cell Biol
, vol.149
, pp. 423-430
-
-
Ueda, H.1
Abbi, S.2
Zheng, C.3
Guan, J.L.4
-
32
-
-
0036734653
-
Regulation of focal adhesion kinase by a novel protein inhibitor FIP200
-
PMID:12221124
-
Abbi S, Ueda H, Zheng C, Cooper LA, Zhao J, Christopher R, et al. Regulation of focal adhesion kinase by a novel protein inhibitor FIP200. Mol Biol Cell 2002; 13:3178-91; PMID:12221124; http://dx.doi.org/10.1091/mbc.E02-05- 0295
-
(2002)
Mol Biol Cell
, vol.13
, pp. 3178-3191
-
-
Abbi, S.1
Ueda, H.2
Zheng, C.3
Cooper, L.A.4
Zhao, J.5
Christopher, R.6
-
33
-
-
85047696381
-
Identification of RB1CC1, a novel human gene that can induce RB1 in various human cells
-
PMID:11850849
-
Chano T, Ikegawa S, Kontani K, Okabe H, Baldini N, Saeki Y. Identification of RB1CC1, a novel human gene that can induce RB1 in various human cells. Oncogene 2002; 21:1295-8; PMID:11850849; http://dx.doi.org/10.1038/ sj.onc.1205178
-
(2002)
Oncogene
, vol.21
, pp. 1295-1298
-
-
Chano, T.1
Ikegawa, S.2
Kontani, K.3
Okabe, H.4
Baldini, N.5
Saeki, Y.6
-
34
-
-
23044453057
-
Mechanism of cell cycle regulation by FIP200 in human breast cancer cells
-
PMID:16061648
-
Melkoumian ZK, Peng X, Gan B, Wu X, Guan JL. Mechanism of cell cycle regulation by FIP200 in human breast cancer cells. Cancer Res 2005; 65:6676-84; PMID:16061648; http://dx.doi. org/10.1158/0008-5472.CAN-04-4142
-
(2005)
Cancer Res
, vol.65
, pp. 6676-6684
-
-
Melkoumian, Z.K.1
Peng, X.2
Gan, B.3
Wu, X.4
Guan, J.L.5
-
35
-
-
23744454765
-
Identification of FIP200 interaction with the TSC1-TSC2 complex and its role in regulation of cell size control
-
PMID:16043512
-
Gan B, Melkoumian ZK, Wu X, Guan KL, Guan JL. Identification of FIP200 interaction with the TSC1-TSC2 complex and its role in regulation of cell size control. J Cell Biol 2005; 170:379-89; PMID:16043512; http://dx.doi.org/10.1083/ jcb.200411106
-
(2005)
J Cell Biol
, vol.170
, pp. 379-389
-
-
Gan, B.1
Melkoumian, Z.K.2
Wu, X.3
Guan, K.L.4
Guan, J.L.5
-
36
-
-
33749562122
-
Role of FIP200 in cardiac and liver development and its regulation of TNFalpha and TSC-mTOR signaling pathways
-
PMID:17015619
-
Gan B, Peng X, Nagy T, Alcaraz A, Gu H, Guan JL. Role of FIP200 in cardiac and liver development and its regulation of TNFalpha and TSC-mTOR signaling pathways. J Cell Biol 2006; 175:121-33; PMID:17015619; http://dx.doi.org/10.1083/jcb.200604129
-
(2006)
J Cell Biol
, vol.175
, pp. 121-133
-
-
Gan, B.1
Peng, X.2
Nagy, T.3
Alcaraz, A.4
Gu, H.5
Guan, J.L.6
-
37
-
-
66449083078
-
ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy
-
PMID:19258318
-
Ganley IG, Lam H, Wang J, Ding X, Chen S, Jiang X. ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy. J Biol Chem 2009; 284:12297-305; PMID:19258318; http://dx.doi.org/10.1074/jbc.M900573200
-
(2009)
J Biol Chem
, vol.284
, pp. 12297-12305
-
-
Ganley, I.G.1
Lam, H.2
Wang, J.3
Ding, X.4
Chen, S.5
Jiang, X.6
-
38
-
-
65249176304
-
ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery
-
PMID:19225151
-
Jung CH, Jun CB, Ro SH, Kim YM, Otto NM, Cao J, et al. ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery. Mol Biol Cell 2009; 20:1992-2003; PMID:19225151; http://dx.doi.org/10.1091/mbc.E08-12-1249
-
(2009)
Mol Biol Cell
, vol.20
, pp. 1992-2003
-
-
Jung, C.H.1
Jun, C.B.2
Ro, S.H.3
Kim, Y.M.4
Otto, N.M.5
Cao, J.6
-
39
-
-
65249119430
-
Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy
-
PMID:19211835
-
Hosokawa N, Hara T, Kaizuka T, Kishi C, Takamura A, Miura Y, et al. Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy. Mol Biol Cell 2009; 20:1981-91; PMID:19211835; http://dx.doi.org/10.1091/mbc.E08-12-1248
-
(2009)
Mol Biol Cell
, vol.20
, pp. 1981-1991
-
-
Hosokawa, N.1
Hara, T.2
Kaizuka, T.3
Kishi, C.4
Takamura, A.5
Miura, Y.6
-
40
-
-
84873569898
-
Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex-dependent and -independent autophagy
-
PMID:23262492
-
Gammoh N, Florey O, Overholtzer M, Jiang X. Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex-dependent and -independent autophagy. Nat Struct Mol Biol 2013; 20:144-9; PMID:23262492; http://dx.doi. org/10.1038/nsmb.2475
-
(2013)
Nat Struct Mol Biol
, vol.20
, pp. 144-149
-
-
Gammoh, N.1
Florey, O.2
Overholtzer, M.3
Jiang, X.4
-
41
-
-
84871581862
-
Architecture of the Atg17 complex as a scaffold for autophagosome biogenesis
-
PMID:23219485
-
Ragusa MJ, Stanley RE, Hurley JH. Architecture of the Atg17 complex as a scaffold for autophagosome biogenesis. Cell 2012; 151:1501-12; PMID:23219485; http://dx.doi.org/10.1016/j.cell.2012.11.028
-
(2012)
Cell
, vol.151
, pp. 1501-1512
-
-
Ragusa, M.J.1
Stanley, R.E.2
Hurley, J.H.3
-
42
-
-
21044455137
-
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
-
PMID:15866887
-
Komatsu M, Waguri S, Ueno T, Iwata J, Murata S, Tanida I, et al. Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice. J Cell Biol 2005; 169:425-34; PMID:15866887; http://dx.doi.org/10.1083/ jcb.200412022
-
(2005)
J Cell Biol
, vol.169
, pp. 425-434
-
-
Komatsu, M.1
Waguri, S.2
Ueno, T.3
Iwata, J.4
Murata, S.5
Tanida, I.6
-
43
-
-
11144245626
-
The role of autophagy during the early neonatal starvation period
-
PMID:15525940
-
Kuma A, Hatano M, Matsui M, Yamamoto A, Nakaya H, Yoshimori T, et al. The role of autophagy during the early neonatal starvation period. Nature 2004; 432:1032-6; PMID:15525940; http://dx.doi. org/10.1038/nature03029
-
(2004)
Nature
, vol.432
, pp. 1032-1036
-
-
Kuma, A.1
Hatano, M.2
Matsui, M.3
Yamamoto, A.4
Nakaya, H.5
Yoshimori, T.6
-
44
-
-
77449094358
-
Neural-specific deletion of FIP200 leads to cerebellar degeneration caused by increased neuronal death and axon degeneration
-
PMID:19940130
-
Liang CC, Wang C, Peng X, Gan B, Guan JL. Neural-specific deletion of FIP200 leads to cerebellar degeneration caused by increased neuronal death and axon degeneration. J Biol Chem 2010; 285:3499-509; PMID:19940130; http://dx.doi.org/10.1074/jbc. M109.072389
-
(2010)
J Biol Chem
, vol.285
, pp. 3499-3509
-
-
Liang, C.C.1
Wang, C.2
Peng, X.3
Gan, B.4
Guan, J.L.5
-
45
-
-
33745192802
-
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
-
PMID:16625204
-
Hara T, Nakamura K, Matsui M, Yamamoto A, Nakahara Y, Suzuki-Migishima R, et al. Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 2006; 441:885-9; PMID:16625204; http://dx.doi. org/10.1038/nature04724
-
(2006)
Nature
, vol.441
, pp. 885-889
-
-
Hara, T.1
Nakamura, K.2
Matsui, M.3
Yamamoto, A.4
Nakahara, Y.5
Suzuki-Migishima, R.6
-
46
-
-
78649689953
-
FIP200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells
-
PMID:20716775
-
Liu F, Lee JY, Wei H, Tanabe O, Engel JD, Morrison SJ, et al. FIP200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells. Blood 2010; 116:4806-14; PMID:20716775; http://dx.doi. org/10.1182/blood-2010- 06-288589
-
(2010)
Blood
, vol.116
, pp. 4806-4814
-
-
Liu, F.1
Lee, J.Y.2
Wei, H.3
Tanabe, O.4
Engel, J.D.5
Morrison, S.J.6
-
47
-
-
51649124519
-
Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation
-
PMID:18539900
-
Kundu M, Lindsten T, Yang CY, Wu J, Zhao F, Zhang J, et al. Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation. Blood 2008; 112:1493-502; PMID:18539900; http://dx.doi.org/10.1182/blood-2008-02-137398
-
(2008)
Blood
, vol.112
, pp. 1493-1502
-
-
Kundu, M.1
Lindsten, T.2
Yang, C.Y.3
Wu, J.4
Zhao, F.5
Zhang, J.6
-
48
-
-
0032509302
-
C. Elegans sequencing consortium. Genome sequence of the nematode C. Elegans: A platform for investigating biology
-
PMID:9851916
-
C. elegans Sequencing Consortium. Genome sequence of the nematode C. elegans: a platform for investigating biology. Science 1998; 282:2012-8; PMID:9851916; http://dx.doi.org/10.1126/science.282.5396.2012
-
(1998)
Science
, vol.282
, pp. 2012-2018
-
-
-
49
-
-
0026356891
-
Predicting coiled coils from protein sequences
-
PMID:2031185
-
Lupas A, Van Dyke M, Stock J. Predicting coiled coils from protein sequences. Science 1991; 252:1162-4; PMID:2031185; http://dx.doi.org/10.1126/ science.252.5009.1162
-
(1991)
Science
, vol.252
, pp. 1162-1164
-
-
Lupas, A.1
Van Dyke, M.2
Stock, J.3
-
50
-
-
0345167800
-
TSC2 mediates cellular energy response to control cell growth and survival
-
PMID:14651849
-
Inoki K, Zhu T, Guan KL. TSC2 mediates cellular energy response to control cell growth and survival. Cell 2003; 115:577-90; PMID:14651849; http://dx.doi.org/10.1016/S0092-8674(03)00929-2
-
(2003)
Cell
, vol.115
, pp. 577-590
-
-
Inoki, K.1
Zhu, T.2
Guan, K.L.3
-
51
-
-
65249155441
-
An Atg1/Atg13 complex with multiple roles in TOR-mediated autophagy regulation
-
PMID:19225150
-
Chang YY, Neufeld TP. An Atg1/Atg13 complex with multiple roles in TOR-mediated autophagy regulation. Mol Biol Cell 2009; 20:2004-14; PMID:19225150; http://dx.doi.org/10.1091/mbc. E08-12-1250
-
(2009)
Mol Biol Cell
, vol.20
, pp. 2004-2014
-
-
Chang, Y.Y.1
Neufeld, T.P.2
-
52
-
-
79955594279
-
A genome-scale shRNA resource for transgenic RNAi in Drosophila
-
PMID:21460824
-
Ni JQ, Zhou R, Czech B, Liu LP, Holderbaum L, Yang-Zhou D, et al. A genome-scale shRNA resource for transgenic RNAi in Drosophila. Nat Methods 2011; 8:405-7; PMID:21460824; http://dx.doi. org/10.1038/nmeth.1592
-
(2011)
Nat Methods
, vol.8
, pp. 405-407
-
-
Ni, J.Q.1
Zhou, R.2
Czech, B.3
Liu, L.P.4
Holderbaum, L.5
Yang-Zhou, D.6
-
53
-
-
80052287311
-
MiMIC: A highly versatile transposon insertion resource for engineering Drosophila melanogaster genes
-
PMID:21985007
-
Venken KJ, Schulze KL, Haelterman NA, Pan H, He Y, Evans-Holm M, et al. MiMIC: a highly versatile transposon insertion resource for engineering Drosophila melanogaster genes. Nat Methods 2011; 8:737-43; PMID:21985007; http://dx.doi. org/10.1038/nmeth.1662
-
(2011)
Nat Methods
, vol.8
, pp. 737-743
-
-
Venken, K.J.1
Schulze, K.L.2
Haelterman, N.A.3
Pan, H.4
He, Y.5
Evans-Holm, M.6
-
55
-
-
0033581027
-
Preventing neurodegeneration in the Drosophila mutant bubblegum
-
PMID:10373116
-
Min KT, Benzer S. Preventing neurodegeneration in the Drosophila mutant bubblegum. Science 1999; 284:1985-8; PMID:10373116; http://dx.doi. org/10.1126/science.284.5422.1985
-
(1999)
Science
, vol.284
, pp. 1985-1988
-
-
Min, K.T.1
Benzer, S.2
-
56
-
-
0031282443
-
Spongecake and eggroll: Two hereditary diseases in Drosophila resemble patterns of human brain degeneration
-
PMID:9382801
-
Min KT, Benzer S. Spongecake and eggroll: two hereditary diseases in Drosophila resemble patterns of human brain degeneration. Curr Biol 1997; 7:885-8; PMID:9382801; http://dx.doi.org/10.1016/S0960-9822(06)00378-2
-
(1997)
Curr Biol
, vol.7
, pp. 885-888
-
-
Min, K.T.1
Benzer, S.2
-
57
-
-
0037442507
-
Blue cheese mutations define a novel, conserved gene involved in progressive neural degeneration
-
PMID:12598614
-
Finley KD, Edeen PT, Cumming RC, Mardahl-Dumesnil MD, Taylor BJ, Rodriguez MH, et al. blue cheese mutations define a novel, conserved gene involved in progressive neural degeneration. J Neurosci 2003; 23:1254-64; PMID:12598614
-
(2003)
J Neurosci
, vol.23
, pp. 1254-1264
-
-
Finley, K.D.1
Edeen, P.T.2
Cumming, R.C.3
Mardahl-Dumesnil, M.D.4
Taylor, B.J.5
Rodriguez, M.H.6
-
58
-
-
0035940416
-
A conditional tissue-specific transgene expression system using inducible GAL4
-
PMID:11675495
-
Osterwalder T, Yoon KS, White BH, Keshishian H. A conditional tissue-specific transgene expression system using inducible GAL4. Proc Natl Acad Sci U S A 2001; 98:12596-601; PMID:11675495; http://dx.doi.org/10.1073/pnas. 221303298
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 12596-12601
-
-
Osterwalder, T.1
Yoon, K.S.2
White, B.H.3
Keshishian, H.4
-
59
-
-
84866426794
-
Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy
-
PMID:22885598
-
Kraft C, Kijanska M, Kalie E, Siergiejuk E, Lee SS, Semplicio G, et al. Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy. EMBO J 2012; 31:3691-703; PMID:22885598; http://dx.doi.org/10.1038/ emboj.2012.225
-
(2012)
EMBO J
, vol.31
, pp. 3691-3703
-
-
Kraft, C.1
Kijanska, M.2
Kalie, E.3
Siergiejuk, E.4
Lee, S.S.5
Semplicio, G.6
-
60
-
-
27144511477
-
The role of the prothoracic gland in determining critical weight for metamorphosis in Drosophila melanogaster
-
PMID:16182527
-
Mirth C, Truman JW, Riddiford LM. The role of the prothoracic gland in determining critical weight for metamorphosis in Drosophila melanogaster. Curr Biol 2005; 15:1796-807; PMID:16182527; http://dx.doi.org/10.1016/j.cub.2005.09. 017
-
(2005)
Curr Biol
, vol.15
, pp. 1796-1807
-
-
Mirth, C.1
Truman, J.W.2
Riddiford, L.M.3
-
61
-
-
79953139746
-
Drosophila as a model system to study autophagy
-
PMID:20798940
-
Zirin J, Perrimon N. Drosophila as a model system to study autophagy. Semin Immunopathol 2010; 32:363-72; PMID:20798940; http://dx.doi. org/10.1007/s00281-010-0223-y
-
(2010)
Semin Immunopathol
, vol.32
, pp. 363-372
-
-
Zirin, J.1
Perrimon, N.2
-
62
-
-
77950509930
-
Autophagy takes flight in Drosophila
-
PMID:20079355
-
Chang YY, Neufeld TP. Autophagy takes flight in Drosophila. FEBS Lett 2010; 584:1342-9; PMID:20079355; http://dx.doi.org/10.1016/j. febslet.2010.01.006
-
(2010)
FEBS Lett
, vol.584
, pp. 1342-1349
-
-
Chang, Y.Y.1
Neufeld, T.P.2
-
63
-
-
34248562237
-
Focal adhesion kinase controls morphogenesis of the Drosophila optic stalk
-
PMID:17360775
-
Murakami S, Umetsu D, Maeyama Y, Sato M, Yoshida S, Tabata T. Focal adhesion kinase controls morphogenesis of the Drosophila optic stalk. Development 2007; 134:1539-48; PMID:17360775; http://dx.doi.org/10.1242/dev. 001529
-
(2007)
Development
, vol.134
, pp. 1539-1548
-
-
Murakami, S.1
Umetsu, D.2
Maeyama, Y.3
Sato, M.4
Yoshida, S.5
Tabata, T.6
-
64
-
-
0029894254
-
RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin e in Drosophila
-
PMID:8675008
-
Du W, Vidal M, Xie JE, Dyson N. RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila. Genes Dev 1996; 10:1206-18; PMID:8675008; http://dx.doi. org/10.1101/gad.10.10.1206
-
(1996)
Genes Dev
, vol.10
, pp. 1206-1218
-
-
Du, W.1
Vidal, M.2
Xie, J.E.3
Dyson, N.4
-
65
-
-
79958171117
-
Characterization of a Drosophila Alzheimer's disease model: Pharmacological rescue of cognitive defects
-
PMID:21673973
-
Chakraborty R, Vepuri V, Mhatre SD, Paddock BE, Miller S, Michelson SJ, et al. Characterization of a Drosophila Alzheimer's disease model: pharmacological rescue of cognitive defects. PLoS One 2011; 6:e20799; PMID:21673973; http://dx.doi.org/10.1371/journal.pone.0020799
-
(2011)
PLoS One
, vol.6
-
-
Chakraborty, R.1
Vepuri, V.2
Mhatre, S.D.3
Paddock, B.E.4
Miller, S.5
Michelson, S.J.6
-
66
-
-
33745602748
-
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
-
PMID:16672980
-
Park J, Lee SB, Lee S, Kim Y, Song S, Kim S, et al. Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin. Nature 2006; 441:1157-61; PMID:16672980; http://dx.doi. org/10.1038/nature04788
-
(2006)
Nature
, vol.441
, pp. 1157-1161
-
-
Park, J.1
Lee, S.B.2
Lee, S.3
Kim, Y.4
Song, S.5
Kim, S.6
-
67
-
-
0034704752
-
A Drosophila model of Parkinson's disease
-
PMID:10746727
-
Feany MB, Bender WW. A Drosophila model of Parkinson's disease. Nature 2000; 404:394-8; PMID:10746727; http://dx.doi.org/10.1038/35006074
-
(2000)
Nature
, vol.404
, pp. 394-398
-
-
Feany, M.B.1
Bender, W.W.2
-
68
-
-
2142645114
-
Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila
-
PMID:15102905
-
Greeve I, Kretzschmar D, Tschäpe JA, Beyn A, Brellinger C, Schweizer M, et al. Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila. J Neurosci 2004; 24:3899-906; PMID:15102905; http://dx.doi. org/10.1523/JNEUROSCI.0283-04.2004
-
(2004)
J Neurosci
, vol.24
, pp. 3899-3906
-
-
Greeve, I.1
Kretzschmar, D.2
Tschäpe, J.A.3
Beyn, A.4
Brellinger, C.5
Schweizer, M.6
-
69
-
-
0035829720
-
Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila
-
PMID:11709151
-
Gunawardena S, Goldstein LS. Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila. Neuron 2001; 32:389-401; PMID:11709151; http://dx.doi. org/10.1016/S0896-6273(01)00496-2
-
(2001)
Neuron
, vol.32
, pp. 389-401
-
-
Gunawardena, S.1
Goldstein, L.S.2
-
70
-
-
33847660443
-
An optimized transgenesis system for Drosophila using germ-line-specific phiC31 integrases
-
PMID:17360644
-
Bischof J, Maeda RK, Hediger M, Karch F, Basler K. An optimized transgenesis system for Drosophila using germ-line-specific phiC31 integrases. Proc Natl Acad Sci U S A 2007; 104:3312-7; PMID:17360644; http://dx.doi.org/10. 1073/pnas.0611511104
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 3312-3317
-
-
Bischof, J.1
Maeda, R.K.2
Hediger, M.3
Karch, F.4
Basler, K.5
-
71
-
-
77749264562
-
Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies
-
PMID:20203043
-
Lee JH, Budanov AV, Park EJ, Birse R, Kim TE, Perkins GA, et al. Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies. Science 2010; 327:1223-8; PMID:20203043; http://dx.doi. org/10.1126/science.1182228
-
(2010)
Science
, vol.327
, pp. 1223-1228
-
-
Lee, J.H.1
Budanov, A.V.2
Park, E.J.3
Birse, R.4
Kim, T.E.5
Perkins, G.A.6
-
72
-
-
61949220840
-
Genetic manipulation and monitoring of autophagy in Drosophila
-
PMID:19185744
-
Neufeld TP. Genetic manipulation and monitoring of autophagy in Drosophila. Methods Enzymol 2008; 451:653-67; PMID:19185744; http://dx.doi. org/10.1016/S0076-6879(08)03236-9
-
(2008)
Methods Enzymol
, vol.451
, pp. 653-667
-
-
Neufeld, T.P.1
-
73
-
-
0142102536
-
In vivo p53 function is indispensable for DNA damageinduced apoptotic signaling in Drosophila
-
PMID:12935877
-
Lee JH, Lee E, Park J, Kim E, Kim J, Chung J. In vivo p53 function is indispensable for DNA damageinduced apoptotic signaling in Drosophila. FEBS Lett 2003; 550:5-10; PMID:12935877; http://dx.doi.org/10.1016/S0014-5793(03)00771-3
-
(2003)
FEBS Lett
, vol.550
, pp. 5-10
-
-
Lee, J.H.1
Lee, E.2
Park, J.3
Kim, E.4
Kim, J.5
Chung, J.6
-
74
-
-
33745212865
-
JNK pathway mediates apoptotic cell death induced by tumor suppressor LKB1 in Drosophila
-
PMID:16273080
-
Lee JH, Koh H, Kim M, Park J, Lee SY, Lee S, et al. JNK pathway mediates apoptotic cell death induced by tumor suppressor LKB1 in Drosophila. Cell Death Differ 2006; 13:1110-22; PMID:16273080; http://dx.doi.org/10.1038/sj.cdd.4401790
-
(2006)
Cell Death Differ
, vol.13
, pp. 1110-1122
-
-
Lee, J.H.1
Koh, H.2
Kim, M.3
Park, J.4
Lee, S.Y.5
Lee, S.6
-
75
-
-
33746322707
-
Inhibition of ERK-MAP kinase signaling by RSK during Drosophila development
-
PMID:16763554
-
Kim M, Lee JH, Koh H, Lee SY, Jang C, Chung CJ, et al. Inhibition of ERK-MAP kinase signaling by RSK during Drosophila development. EMBO J 2006; 25:3056-67; PMID:16763554; http://dx.doi. org/10.1038/sj.emboj.7601180
-
(2006)
EMBO J
, vol.25
, pp. 3056-3067
-
-
Kim, M.1
Lee, J.H.2
Koh, H.3
Lee, S.Y.4
Jang, C.5
Chung, C.J.6
-
76
-
-
34250827107
-
Energy-dependent regulation of cell structure by AMP-activated protein kinase
-
PMID:17486097
-
Lee JH, Koh H, Kim M, Kim Y, Lee SY, Karess RE, et al. Energy-dependent regulation of cell structure by AMP-activated protein kinase. Nature 2007; 447:1017-20; PMID:17486097; http://dx.doi. org/10.1038/nature05828
-
(2007)
Nature
, vol.447
, pp. 1017-1020
-
-
Lee, J.H.1
Koh, H.2
Kim, M.3
Kim, Y.4
Lee, S.Y.5
Karess, R.E.6
|