IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome

Journal of Cell Biology

Volumn 187, Issue 7, 2009, Pages 1083-1099

  Thompson, Leslie Michels ^a   Aiken, Charity T ^b   Kaltenbach, Linda S ^c   Agrawal, Namita ^b   Illes, Katalin ^a   Khoshnan, Ali ^d   Martinez Vincente, Marta ^e,f   Arrasate, Montserrat ^g   O'Rourke, Jacqueline Gire ^a   Khashwji, Hasan ^a   Lukacsovich, Tamas ^b   Zhu, Ya Zhen ^a   Lau, Alice L ^a   Massey, Ashish ^e   Hayden, Michael R ^h   Zeitlin, Scott O ⁱ   Finkbeiner, Steven ^j   Green, Kim N ^a   LaFerla, Frank M ^a   Bates, Gillian ^k   Huang, Lan ^a,b   Patterson, Paul H ^d   Lo, Donald C ^c   Cuervo, Ana Maria ^e   Marsh, J Lawrence ^b   Steffan, Joan S ^a   more..

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^e ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^f HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^g UNIVERSITY OF NAVARRA   (Spain)

^h UNIVERSITY OF BRITISH COLUMBIA   (Canada)

ⁱ UNIVERSITY OF VIRGINIA   (United States)

^j UNIVERSITY OF CALIFORNIA   (United States)

^k KING'S COLLEGE LONDON   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

HUNTINGTIN; I KAPPA B KINASE; MUTANT PROTEIN; PROTEASOME;

ACETYLATION; ARTICLE; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; LYSOSOME; NEUROTOXICITY; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN PROCESSING; SUMOYLATION; UBIQUITINATION;

ANIMALS; BRAIN; CELL LINE; HUMANS; I-KAPPA B KINASE; LYSOSOMES; MICE; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN STRUCTURE, TERTIARY; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; UBIQUITINATION;

EID: 72149124383     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.200909067     Document Type: Article

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